{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T20:43:47Z","timestamp":1792701827580,"version":"4.5.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","jamda.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Medical Directors Association"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.jamda.2024.105335","type":"journal-article","created":{"date-parts":[[2024,11,2]],"date-time":"2024-11-02T21:34:26Z","timestamp":1730583266000},"page":"105335","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Higher Magnesium Intake Is Associated with a Lower Risk of Frailty in Older Adults"],"prefix":"10.1016","volume":"26","author":[{"given":"Ligia J.","family":"Dominguez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana M.","family":"M\u00e9rida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Donat-Vargas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 R.","family":"Banegas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Veronese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Barbagallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Rodr\u00edguez-Artalejo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Guallar-Castill\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jamda.2024.105335_bib1","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/S0140-6736(12)62167-9","article-title":"Frailty in elderly people","volume":"381","author":"Clegg","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.jamda.2024.105335_bib2","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.jamda.2013.03.022","article-title":"Frailty consensus: a call to action","volume":"14","author":"Morley","year":"2013","journal-title":"J\u00a0Am Med Dir Assoc"},{"key":"10.1016\/j.jamda.2024.105335_bib3","doi-asserted-by":"crossref","first-page":"M146","DOI":"10.1093\/gerona\/56.3.M146","article-title":"Frailty in older adults: evidence for a phenotype","volume":"56","author":"Fried","year":"2001","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jamda.2024.105335_bib4","doi-asserted-by":"crossref","first-page":"1163.e1","DOI":"10.1016\/j.jamda.2016.09.010","article-title":"Frailty and the prediction of negative health outcomes: a meta-analysis","volume":"17","author":"Vermeiren","year":"2016","journal-title":"J\u00a0Am Med Dir Assoc"},{"key":"10.1016\/j.jamda.2024.105335_bib5","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1093\/ageing\/afaa219","article-title":"Prevalence of frailty in 62 countries across the world: a systematic review and meta-analysis of population-level studies","volume":"50","author":"O'Caoimh","year":"2021","journal-title":"Age Ageing"},{"key":"10.1016\/j.jamda.2024.105335_bib6","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1016\/S0140-6736(15)00516-4","article-title":"The world report on ageing and health: a policy framework for healthy ageing","volume":"387","author":"Beard","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.jamda.2024.105335_bib7","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s12603-021-1703-6","article-title":"Editorial: anorexia of ageing: pathway to frailty and Sarcopenia","volume":"26","author":"Merchant","year":"2022","journal-title":"J\u00a0Nutr Health Aging"},{"key":"10.1016\/j.jamda.2024.105335_bib8","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3390\/nu13010139","article-title":"Magnesium and hypertension in old age","volume":"13","author":"Dominguez","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.jamda.2024.105335_bib9","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0098-2997(02)00090-0","article-title":"Role of magnesium in insulin action, diabetes and cardio-metabolic syndrome X","volume":"24","author":"Barbagallo","year":"2003","journal-title":"Mol Aspects Med"},{"key":"10.1016\/j.jamda.2024.105335_bib10","doi-asserted-by":"crossref","first-page":"714","DOI":"10.3390\/nu14030714","article-title":"Magnesium in type 2 diabetes mellitus, obesity, and metabolic syndrome","volume":"14","author":"Barbagallo","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.jamda.2024.105335_bib11","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.3389\/fphys.2019.01454","article-title":"Age and muscle function are more closely associated with intracellular magnesium, as assessed by (31)P magnetic resonance spectroscopy, than with serum magnesium","volume":"10","author":"Cameron","year":"2019","journal-title":"Front Physiol"},{"key":"10.1016\/j.jamda.2024.105335_bib12","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/ajcn\/84.2.419","article-title":"Magnesium and muscle performance in older persons: the InCHIANTI study","volume":"84","author":"Dominguez","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jamda.2024.105335_bib13","doi-asserted-by":"crossref","first-page":"974","DOI":"10.3945\/ajcn.113.080168","article-title":"Effect of oral magnesium supplementation on physical performance in healthy elderly women involved in a weekly exercise program: a randomized controlled trial","volume":"100","author":"Veronese","year":"2014","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jamda.2024.105335_bib14","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/jbmr.2692","article-title":"Dietary magnesium is positively associated with skeletal muscle power and indices of muscle mass and may attenuate the association between circulating C-reactive protein and muscle mass in women","volume":"31","author":"Welch","year":"2016","journal-title":"J\u00a0Bone Miner Res"},{"key":"10.1016\/j.jamda.2024.105335_bib15","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.3390\/nu9111253","article-title":"Dietary magnesium and incident frailty in older people at risk for knee osteoarthritis: an eight-year longitudinal study","volume":"9","author":"Veronese","year":"2017","journal-title":"Nutrients"},{"key":"10.1016\/j.jamda.2024.105335_bib16","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/s12603-023-1979-9","article-title":"Association between elevated magnesium intake and reduced risk of recurrent falls and frailty in osteoarthritis: data from the osteoarthritis Initiative","volume":"27","author":"Zheng","year":"2023","journal-title":"J\u00a0Nutr Health Aging"},{"key":"10.1016\/j.jamda.2024.105335_bib17","first-page":"876","article-title":"[Rationale and methods of the study on nutrition and cardiovascular risk in Spain (ENRICA)]","volume":"64","author":"Rodriguez-Artalejo","year":"2011","journal-title":"Rev Esp Cardiol"},{"key":"10.1016\/j.jamda.2024.105335_bib18","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12916-014-0255-6","article-title":"Major dietary patterns and risk of frailty in older adults: a prospective cohort study","volume":"13","author":"Leon-Munoz","year":"2015","journal-title":"BMC Med"},{"key":"10.1016\/j.jamda.2024.105335_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0086074","article-title":"Validity and reproducibility of a Spanish dietary history","volume":"9","author":"Guallar-Castillon","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jamda.2024.105335_bib20","series-title":"Tablas de Composici\u00f3n de Alimentos","author":"Moreiras","year":"2007"},{"key":"10.1016\/j.jamda.2024.105335_bib21","series-title":"Tablas de Composici\u00f3n de Alimentos del Centro de Ense\u00f1anza Superior de Nutrici\u00f3n y Diet\u00e9tica (CESNID); Sociedad Espa\u00f1ola de Nutrici\u00f3n","author":"Farr\u00e1n","year":"2004"},{"key":"10.1016\/j.jamda.2024.105335_bib22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0045413","article-title":"Validation of the Spanish center for epidemiological studies depression and zung self-rating depression scales: a comparative validation study","volume":"7","author":"Ruiz-Grosso","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jamda.2024.105335_bib23","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1007\/s12603-011-0075-8","article-title":"The prevalence of frailty syndrome in an older population from Spain. The toledo study for healthy aging","volume":"15","author":"Garcia-Garcia","year":"2011","journal-title":"J\u00a0Nutr Health Aging"},{"key":"10.1016\/j.jamda.2024.105335_bib24","doi-asserted-by":"crossref","first-page":"M85","DOI":"10.1093\/geronj\/49.2.M85","article-title":"A\u00a0short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission","volume":"49","author":"Guralnik","year":"1994","journal-title":"J\u00a0Gerontol"},{"key":"10.1016\/j.jamda.2024.105335_bib25","doi-asserted-by":"crossref","first-page":"2599","DOI":"10.1056\/NEJMoa025039","article-title":"Adherence to a mediterranean diet and survival in a Greek population","volume":"348","author":"Trichopoulou","year":"2003","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jamda.2024.105335_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2023.112180","article-title":"Rationale of the association between mediterranean diet and the risk of frailty in older adults and systematic review and meta-analysis","volume":"177","author":"Dominguez","year":"2023","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.jamda.2024.105335_bib27","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1093\/gerona\/gly148","article-title":"Consensus on shared measures of mobility and cognition: from the Canadian consortium on neurodegeneration in aging (CCNA)","volume":"74","author":"Montero-Odasso","year":"2019","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.jamda.2024.105335_bib28","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.cger.2010.03.001","article-title":"Epidemiology of osteoarthritis","volume":"26","author":"Zhang","year":"2010","journal-title":"Clin Geriatr Med"},{"key":"10.1016\/j.jamda.2024.105335_bib29","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3390\/nu13020463","article-title":"Magnesium in aging, health and diseases","volume":"13","author":"Barbagallo","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.jamda.2024.105335_bib30","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1007\/s12603-014-0568-3","article-title":"Frailty and nutrition: searching for evidence","volume":"19","author":"Bonnefoy","year":"2015","journal-title":"J\u00a0Nutr Health Aging"},{"key":"10.1016\/j.jamda.2024.105335_bib31","doi-asserted-by":"crossref","first-page":"496","DOI":"10.3390\/nu16040496","article-title":"Magnesium and the hallmarks of aging","volume":"16","author":"Dominguez","year":"2024","journal-title":"Nutrients"},{"key":"10.1016\/j.jamda.2024.105335_bib32","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.clnu.2018.01.014","article-title":"Cross-sectional associations of dietary and circulating magnesium with skeletal muscle mass in the EPIC-Norfolk cohort","volume":"38","author":"Hayhoe","year":"2019","journal-title":"Clin Nutr"},{"key":"10.1016\/j.jamda.2024.105335_bib33","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.clnu.2015.11.013","article-title":"Nutritional status, body composition, and quality of life in community-dwelling sarcopenic and non-sarcopenic older adults: a case-control study","volume":"36","author":"Verlaan","year":"2017","journal-title":"Clin Nutr"},{"key":"10.1016\/j.jamda.2024.105335_bib34","first-page":"930","article-title":"Dietary magnesium depletion affects metabolic responses during submaximal exercise in postmenopausal women","volume":"132","author":"Lukaski","year":"2002","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.jamda.2024.105335_bib35","first-page":"2879","article-title":"Dietary magnesium intake in a national sample of US adults","volume":"133","author":"Ford","year":"2003","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.jamda.2024.105335_bib36","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.abb.2006.03.031","article-title":"Magnesium and the inflammatory response: potential physiopathological implications","volume":"458","author":"Mazur","year":"2007","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.jamda.2024.105335_bib37","doi-asserted-by":"crossref","first-page":"679","DOI":"10.3390\/nu14030679","article-title":"Effect of magnesium supplementation on inflammatory parameters: a meta-analysis of randomized controlled trials","volume":"14","author":"Veronese","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.jamda.2024.105335_bib38","doi-asserted-by":"crossref","first-page":"262","DOI":"10.5582\/bst.2023.01184","article-title":"Geriatric syndromes, chronic inflammation, and advances in the management of frailty: a review with new insights","volume":"17","author":"Li","year":"2023","journal-title":"Biosci Trends"},{"key":"10.1016\/j.jamda.2024.105335_bib39","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1038\/s43587-021-00082-y","article-title":"An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging","volume":"1","author":"Sayed","year":"2021","journal-title":"Nat Aging"},{"key":"10.1016\/j.jamda.2024.105335_bib40","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jamda.2017.08.006","article-title":"The relationship between the dietary inflammatory index and incident frailty: a longitudinal cohort study","volume":"19","author":"Shivappa","year":"2018","journal-title":"J\u00a0Am Med Dir Assoc"}],"container-title":["Journal of the American Medical Directors Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525861024007576?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525861024007576?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,25]],"date-time":"2024-12-25T01:01:02Z","timestamp":1735088462000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525861024007576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S1525861024007576"],"URL":"https:\/\/doi.org\/10.1016\/j.jamda.2024.105335","relation":{},"ISSN":["1525-8610"],"issn-type":[{"value":"1525-8610","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Higher Magnesium Intake Is Associated with a Lower Risk of Frailty in Older Adults","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Medical Directors Association","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jamda.2024.105335","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Post-Acute and Long-Term Care Medical Association.","name":"copyright","label":"Copyright"}],"article-number":"105335"}}