{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:09:00Z","timestamp":1783487340349,"version":"3.55.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Research"],"published-print":{"date-parts":[[2015,11]]},"DOI":"10.1016\/j.jare.2014.10.007","type":"journal-article","created":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T12:33:23Z","timestamp":1414845203000},"page":"941-948","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"title":["Microwave assisted one-pot catalyst free green synthesis of new methyl-7-amino-4-oxo-5-phenyl-2-thioxo-2,3,4,5-tetrahydro-1H-pyrano[2,3-d]pyrimidine-6-carboxylates as potent in vitro antibacterial and antifungal activity"],"prefix":"10.1016","volume":"6","author":[{"given":"Ajmal R.","family":"Bhat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aabid H.","family":"Shalla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajendra S.","family":"Dongre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jare.2014.10.007_b0005","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1002\/(SICI)1097-4660(199704)68:4<381::AID-JCTB620>3.0.CO;2-3","article-title":"Catalysis: the key to waste minimization","volume":"68","author":"Sheldon","year":"1997","journal-title":"J Chem Technol Biotechnol"},{"key":"10.1016\/j.jare.2014.10.007_b0010","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1080\/17518251003749353","article-title":"Novel pyrimidine derivatives by sonication and traditional thermal methods","volume":"3","author":"Dabholkar","year":"2010","journal-title":"Green Chem Lett Rev"},{"issue":"1","key":"10.1016\/j.jare.2014.10.007_b0015","first-page":"422","article-title":"Potent in-vitro antibacterial and antifungal activities of pyrano[2,3-d]pyrimidine derivatives with quantitative yield","volume":"5","author":"Ajmal","year":"2014","journal-title":"Int J Pharm Bio Sci"},{"issue":"13","key":"10.1016\/j.jare.2014.10.007_b0020","doi-asserted-by":"crossref","first-page":"6678","DOI":"10.1016\/j.bmc.2005.07.043","article-title":"Dihydropyrido [2,3-d]pyrimidines as a new class of antileishmanial agents","volume":"24","author":"Agarwal","year":"2005","journal-title":"J Bio-org Med Chem"},{"key":"10.1016\/j.jare.2014.10.007_b0025","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1021\/jm00278a009","article-title":"Antimalarial and antimetabolite effects of 2,4-diamino-6-[(benzyl)amino]pyrido [2,3-d]-pyrimidines","volume":"15","author":"Davoll","year":"1972","journal-title":"J Med Chem"},{"key":"10.1016\/j.jare.2014.10.007_b0030","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1021\/jm00177a025","article-title":"Synthesis and antitumor activity of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine","volume":"23","author":"Grivsky","year":"1980","journal-title":"J Med Chem"},{"key":"10.1016\/j.jare.2014.10.007_b0035","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/ardp.200700005","article-title":"Synthesis of pyrazolo[4,3:5,6]pyrano[2,3-d]pyrimidine derivatives for antiviral evaluation","volume":"340","author":"Shamroukh","year":"2007","journal-title":"Arch Pharm"},{"key":"10.1016\/j.jare.2014.10.007_b0040","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1021\/jm00136a006","article-title":"Antihypertensive activity of 6-arylpyrido[2,3-d]pyrimidin-7-amine derivatives","volume":"24","author":"Bennett","year":"1981","journal-title":"J Med Chem"},{"key":"10.1016\/j.jare.2014.10.007_b0045","series-title":"Organic synthesis in water","author":"Grieco","year":"1998"},{"key":"10.1016\/j.jare.2014.10.007_b0050","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1021\/cr030009u","article-title":"Organic reactions in aqueous media with a focus on carbon\u2013carbon bond formations: a decade update","volume":"105","author":"Li","year":"2005","journal-title":"Chem Rev"},{"key":"10.1016\/j.jare.2014.10.007_b0055","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1021\/cr800448q","article-title":"Organic synthesis on water","volume":"109","author":"Chanda","year":"2009","journal-title":"Chem Rev"},{"key":"10.1016\/j.jare.2014.10.007_b0060","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/17518250701882441","article-title":"Green chemistry: the emergence of a transformative framework","volume":"1","author":"Anastasa","year":"2007","journal-title":"Green Chem Lett Rev"},{"key":"10.1016\/j.jare.2014.10.007_b0065","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1021\/ar700238s","article-title":"Microwave assisted organic synthesis and transformations using benign reaction media","volume":"41","author":"Polshettiwar","year":"2008","journal-title":"Acc Chem Res"},{"key":"10.1016\/j.jare.2014.10.007_b0070","doi-asserted-by":"crossref","first-page":"340","DOI":"10.2174\/1389557510909030340","article-title":"The application of microwave irradiation as new convenient synthetic procedure in drug discovery","volume":"9","author":"Santagada","year":"2009","journal-title":"Mini Rev Med Chem"},{"key":"10.1016\/j.jare.2014.10.007_b0075","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1021\/op050227k","article-title":"Green chemistry, a pharmaceutical","volume":"10","author":"Tucker","year":"2006","journal-title":"Org Process Res Dev"},{"key":"10.1016\/j.jare.2014.10.007_b0080","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1039\/C1GC15837F","article-title":"Environmentally benign synthesis of heterocyclic compounds by combined microwave-assisted heterogeneous catalytic approaches","volume":"14","author":"Dastan","year":"2012","journal-title":"Green Chem"},{"key":"10.1016\/j.jare.2014.10.007_b0085","volume":"vol. 147","author":"Loupy","year":"2002"},{"issue":"1","key":"10.1016\/j.jare.2014.10.007_b0090","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1039\/a808223e","article-title":"Solvent-free organic syntheses. using supported reagents and microwave irradiation","volume":"1","author":"Varma","year":"1999","journal-title":"Green Chem"},{"issue":"46","key":"10.1016\/j.jare.2014.10.007_b0095","doi-asserted-by":"crossref","first-page":"6250","DOI":"10.1002\/anie.200400655","article-title":"Controlled microwave heating in modern organic synthesis","volume":"43","author":"Kappe","year":"2004","journal-title":"Angew Chem Int Ed"},{"key":"10.1016\/j.jare.2014.10.007_b0100","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/15533171003629121","article-title":"Eco-friendly and efficient synthesis of Pyrano[2,3-d] pyrimidinone and Tetrahydrobenzo[b]pyran derivatives in water","volume":"40","author":"Akbar","year":"2010","journal-title":"Synth React Inorg Met-Org Nano-Met Chem"},{"key":"10.1016\/j.jare.2014.10.007_b0105","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1081\/SCC-120030318","article-title":"Effective synthesis of 7-amino-6-cyano-5-aryl-5H-pyrano[2,3-d]pyrimidine-2,4(1H,3H)-diones under microwave irradiation","volume":"34","author":"Gao","year":"2004","journal-title":"Synth Commun"},{"key":"10.1016\/j.jare.2014.10.007_b0110","doi-asserted-by":"crossref","first-page":"162","DOI":"10.3184\/0308234054213672","article-title":"Clean one-pot synthesis of 7-amino-5-aryl-6-cyano-1,5-dihydro-2H-pyrano[2,3-d]pyrimidine-2,4(3H)-diones in aqueous media under ultrasonic irradiation","volume":"3","author":"Jin","year":"2005","journal-title":"J Chem Res"},{"key":"10.1016\/j.jare.2014.10.007_b0115","doi-asserted-by":"crossref","first-page":"474","DOI":"10.3390\/molecules14010474","article-title":"Mechanochemical solvent-free and catalyst-free one-pot synthesis of Pyrano[2,3-d]Pyrimidine-2,4(1H,3H)-Diones with quantitative yields","volume":"14","author":"Sara","year":"2009","journal-title":"Molecules"},{"key":"10.1016\/j.jare.2014.10.007_b0120","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1039\/c2gc35135h","article-title":"Glycerol as a biodegradable and reusable promoting medium for the catalyst free one-pot three component synthesis of 4H-pyrans","volume":"14","author":"Hamid","year":"2012","journal-title":"Green Chem"},{"key":"10.1016\/j.jare.2014.10.007_b0125","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1080\/00397910903174390","article-title":"Zn [(L) proline]2: an efficient catalyst for the synthesis of biologically active pyrano[2,3-d]pyrimidine derivatives","volume":"40","author":"Heravi","year":"2010","journal-title":"Synth Commun"},{"key":"10.1016\/j.jare.2014.10.007_b0130","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s11030-008-9079-7","article-title":"Diammonium hydrogen phosphate as a versatile and efficient catalyst for the one-pot synthesis of pyrano[2,3-d]pyrimidinone derivatives in aqueous media","volume":"12","author":"Balalaie","year":"2008","journal-title":"Mol Diver"},{"key":"10.1016\/j.jare.2014.10.007_b0135","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1007\/BF03245854","article-title":"Amani AM one pot synthesis of pyrano[2,3-d]pyrimidinone derivatives catalyzed by L-proline in aqueous media","volume":"6","author":"Bararjanian","year":"2009","journal-title":"J Iran Chem Soc"},{"key":"10.1016\/j.jare.2014.10.007_b0140","doi-asserted-by":"crossref","first-page":"3133","DOI":"10.1080\/00397910500282661","article-title":"Green synthesis of pyrano[2,3-d]-pyrimidine derivatives in ionic liquids","volume":"35","author":"Yu","year":"2005","journal-title":"Synth Commun"},{"issue":"5","key":"10.1016\/j.jare.2014.10.007_b0145","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.jscs.2011.10.023","article-title":"DABCO promoted one-pot synthesis of dihydropyrano(c) chromene and pyrano[2,3-d]pyrimidine derivatives and their biological activities","volume":"18","author":"Shubha","year":"2014","journal-title":"J Saudi Chem Soc"},{"key":"10.1016\/j.jare.2014.10.007_b0150","unstructured":"Barry AL. The antimicrobial susceptibility test: principle and practices, Illus Lea & Febiger Philadelphia; 1976. p. 180."},{"key":"10.1016\/j.jare.2014.10.007_b0155","doi-asserted-by":"crossref","unstructured":"European Committee for Antimicrobial Susceptibility Testing (EUCAST) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Determination of minimum inhibitory concentrations (MICs) of antibacterial agents by agar dilution, Clin Microbiol Infect Suppl 2000; 6: 509\u2013515.","DOI":"10.1046\/j.1469-0691.2000.00142.x"}],"container-title":["Journal of Advanced Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123214001301?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123214001301?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T20:42:02Z","timestamp":1761856922000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2090123214001301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["S2090123214001301"],"URL":"https:\/\/doi.org\/10.1016\/j.jare.2014.10.007","relation":{},"ISSN":["2090-1232"],"issn-type":[{"value":"2090-1232","type":"print"}],"subject":[],"published":{"date-parts":[[2015,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Microwave assisted one-pot catalyst free green synthesis of new methyl-7-amino-4-oxo-5-phenyl-2-thioxo-2,3,4,5-tetrahydro-1H-pyrano[2,3-d]pyrimidine-6-carboxylates as potent in vitro antibacterial and antifungal activity","name":"articletitle","label":"Article Title"},{"value":"Journal of Advanced Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jare.2014.10.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Production and hosting by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}