{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T23:28:57Z","timestamp":1792970937132,"version":"4.5.0"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,18]],"date-time":"2024-02-18T00:00:00Z","timestamp":1708214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32272894"],"award-info":[{"award-number":["32272894"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2023A1515010646"],"award-info":[{"award-number":["2023A1515010646"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515010944"],"award-info":[{"award-number":["2021A1515010944"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFD1300401"],"award-info":[{"award-number":["2021YFD1300401"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2023M741224"],"award-info":[{"award-number":["2023M741224"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["GZB20230230"],"award-info":[{"award-number":["GZB20230230"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Research"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.jare.2024.02.014","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T21:56:49Z","timestamp":1708379809000},"page":"131-146","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"special_numbering":"C","title":["Melatonin alleviates high temperature exposure induced fetal growth restriction via the gut-placenta-fetus axis in pregnant mice"],"prefix":"10.1016","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2780-8272","authenticated-orcid":false,"given":"Jia-Jin","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caichi","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulong","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangfang","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shihai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wutai","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1154-0438","authenticated-orcid":false,"given":"Fang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jare.2024.02.014_b0005","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.fertnstert.2022.06.005","article-title":"Systematic review of climate change effects on reproductive health","volume":"118","author":"Segal","year":"2022","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jare.2024.02.014_b0010","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1038\/s41559-023-02055-3","article-title":"Species-specific traits mediate avian demographic responses under past climate change","volume":"7","author":"Germain","year":"2023","journal-title":"Nat Ecol Evol"},{"key":"10.1016\/j.jare.2024.02.014_b0015","article-title":"Associations between high temperatures in pregnancy and risk of preterm birth, low birth weight, and stillbirths: systematic review and meta-analysis","volume":"371","author":"Chersich","year":"2020","journal-title":"BMJ"},{"key":"10.1016\/j.jare.2024.02.014_b0020","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.envint.2017.11.004","article-title":"Heat and pregnancy-related emergencies: Risk of placental abruption during hot weather","volume":"111","author":"He","year":"2018","journal-title":"Environ Int"},{"key":"10.1016\/j.jare.2024.02.014_b0025","doi-asserted-by":"crossref","first-page":"853","DOI":"10.3390\/ijerph14080853","article-title":"Heat exposure and maternal health in the face of climate change","volume":"14","author":"Kuehn","year":"2017","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.jare.2024.02.014_b0030","doi-asserted-by":"crossref","first-page":"e968","DOI":"10.1016\/S2542-5196(22)00242-X","article-title":"Environmental heat stress on maternal physiology and fetal blood flow in pregnant subsistence farmers in The Gambia, west Africa: an observational cohort study","volume":"6","author":"Bonell","year":"2022","journal-title":"Lancet Planet Health"},{"key":"10.1016\/j.jare.2024.02.014_b0035","doi-asserted-by":"crossref","first-page":"10333","DOI":"10.1073\/pnas.1820130116","article-title":"Heat stress directly impairs gut integrity and recruits distinct immune cell populations into the bovine intestine","volume":"116","author":"Koch","year":"2019","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jare.2024.02.014_b0040","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1007\/s00018-020-03674-w","article-title":"Regulation of maternal-fetal metabolic communication","volume":"78","author":"Bowman","year":"2021","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.jare.2024.02.014_b0045","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/nri.2017.7","article-title":"Dysbiosis and the immune system","volume":"17","author":"Levy","year":"2017","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.jare.2024.02.014_b0050","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.chom.2017.07.006","article-title":"The gut microbiota, food science, and human nutrition: a timely marriage","volume":"22","author":"Barratt","year":"2017","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jare.2024.02.014_b0055","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1136\/gutjnl-2019-319101","article-title":"Gut dysbiosis induces the development of pre-eclampsia through bacterial translocation","volume":"69","author":"Chen","year":"2020","journal-title":"Gut"},{"key":"10.1016\/j.jare.2024.02.014_b0060","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00076-23","article-title":"Alterations in the gut microbiome and metabolisms in pregnancies with fetal growth restriction","volume":"11","author":"Tao","year":"2023","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.jare.2024.02.014_b0065","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/s41564-018-0278-4","article-title":"The role of the microbiota in infectious diseases","volume":"4","author":"Libertucci","year":"2019","journal-title":"Nat Microbiol"},{"key":"10.1016\/j.jare.2024.02.014_b0070","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.arr.2018.04.004","article-title":"Dysbiosis of gut microbiota and microbial metabolites in Parkinson's Disease","volume":"45","author":"Sun","year":"2018","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.jare.2024.02.014_b0075","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/6367264","article-title":"The gut microbiota dysbiosis in preeclampsia contributed to trophoblast cell proliferation, invasion, and migration via lncRNA BC030099\/NF-\u03baB pathway","volume":"2022","author":"Tang","year":"2022","journal-title":"Mediators Inflamm"},{"key":"10.1016\/j.jare.2024.02.014_b0080","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/pr.2016.176","article-title":"Ureaplasma infection-mediated release of matrix metalloproteinase-9 and PGP: a novel mechanism of preterm rupture of membranes and chorioamnionitis","volume":"81","author":"Lal","year":"2017","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jare.2024.02.014_b0085","doi-asserted-by":"crossref","DOI":"10.1111\/aji.13402","article-title":"Melatonin for the prevention of fetal injury associated with intrauterine inflammation","volume":"86","author":"Kim","year":"2021","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.jare.2024.02.014_b0090","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/biof.1690","article-title":"Ischemic stroke, obesity, and the anti-inflammatory role of melatonin","volume":"47","author":"Yawoot","year":"2021","journal-title":"Biofactors"},{"key":"10.1016\/j.jare.2024.02.014_b0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jare.2022.01.015","article-title":"The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT(1) receptor to promote lung adenocarcinoma growth","volume":"41","author":"Sun","year":"2022","journal-title":"J Adv Res"},{"key":"10.1016\/j.jare.2024.02.014_b0100","article-title":"Assessment of the iodine status of children of pre-school age (6 months\u20135 years) in Rivers State","volume":"3","author":"Orisa","year":"2022","journal-title":"Nigeria eFood"},{"key":"10.1016\/j.jare.2024.02.014_b0105","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/fft2.180","article-title":"Effect of exogenous melatonin in fruit postharvest, crosstalk with hormones, and defense mechanism for oxidative stress management","volume":"4","author":"Sati","year":"2023","journal-title":"Food Frontiers"},{"key":"10.1016\/j.jare.2024.02.014_b0110","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1002\/fft2.207","article-title":"An emerging natural antioxidant therapy for COVID-19 infection patients: current and future directions","volume":"4","author":"Shrivastava","year":"2023","journal-title":"Food Frontiers"},{"key":"10.1016\/j.jare.2024.02.014_b0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-079X.2011.00916.x","article-title":"Melatonin as a natural ally against oxidative stress: a physicochemical examination","volume":"51","author":"Galano","year":"2011","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jare.2024.02.014_b0120","article-title":"In pre-clinical study fetal hypoxia caused autophagy and mitochondrial impairment in ovary granulosa cells mitigated by melatonin supplement","author":"Zhang","year":"2023","journal-title":"J Adv Res"},{"key":"10.1016\/j.jare.2024.02.014_b0125","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/jpi.12075","article-title":"The role of melatonin in the cells of the innate immunity: a review","volume":"55","author":"Calvo","year":"2013","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jare.2024.02.014_b0130","doi-asserted-by":"crossref","first-page":"228","DOI":"10.2174\/157015910792246155","article-title":"Antiinflammatory activity of melatonin in central nervous system","volume":"8","author":"Esposito","year":"2010","journal-title":"Curr Neuropharmacol"},{"key":"10.1016\/j.jare.2024.02.014_b0135","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/jpi.12354","article-title":"Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR-34a\/silent information regulator 1 pathway","volume":"61","author":"Carloni","year":"2016","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jare.2024.02.014_b0140","first-page":"63","article-title":"Maternal administration of melatonin exerts short- and long-term neuroprotective effects on the offspring from lipopolysaccharide-treated mice","author":"Dom\u00ednguez Rubio","year":"2017","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jare.2024.02.014_b0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.124489","article-title":"Melatonin ameliorates ochratoxin A induced liver inflammation, oxidative stress and mitophagy in mice involving in intestinal microbiota and restoring the intestinal barrier function","volume":"407","author":"Zhang","year":"2021","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jare.2024.02.014_b0150","doi-asserted-by":"crossref","DOI":"10.1186\/s40168-022-01452-3","article-title":"Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation","volume":"11","author":"Wang","year":"2023","journal-title":"Microbiome"},{"key":"10.1016\/j.jare.2024.02.014_b0155","article-title":"Gut microbiota dysbiosis induced by decreasing endogenous melatonin mediates the pathogenesis of Alzheimer's disease and obesity","volume":"13","author":"Zhang","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.jare.2024.02.014_b0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113550","article-title":"Effects of the maternal gut microbiome and gut-placental axis on melatonin efficacy in alleviating cadmium-induced fetal growth restriction","volume":"237","author":"Zhang","year":"2022","journal-title":"Ecotoxicol Environ Saf"},{"key":"10.1016\/j.jare.2024.02.014_b0165","article-title":"Loss of Sc5d results in micrognathia due to a failure in osteoblast differentiation","volume":"10","author":"Iwaya","year":"2023","journal-title":"J Adv Res"},{"key":"10.1016\/j.jare.2024.02.014_b0170","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/fft2.138","article-title":"Apios americana Medikus: a novel and promising food for postpartum uterine involution","volume":"3","author":"Li","year":"2022","journal-title":"Food Front"},{"key":"10.1016\/j.jare.2024.02.014_b0175","article-title":"Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia","volume":"6","author":"Li","year":"2020","journal-title":"Sci Adv"},{"key":"10.1016\/j.jare.2024.02.014_b0180","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.theriogenology.2015.09.028","article-title":"Profiling of differential gene expression in the hypothalamus of broiler-type Taiwan country chickens in response to acute heat stress","volume":"85","author":"Tu","year":"2016","journal-title":"Theriogenology"},{"key":"10.1016\/j.jare.2024.02.014_b0185","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1111\/j.1600-079X.2004.00122.x","article-title":"Melatonin reduces cholesterol accumulation and prooxidant state induced by high cholesterol diet in the plasma, the liver and probably in the aorta of C57BL\/6J mice","volume":"36","author":"Sener","year":"2004","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jare.2024.02.014_b0190","doi-asserted-by":"crossref","DOI":"10.1111\/jpi.12591","article-title":"Melatonin for prevention of placental malperfusion and fetal compromise associated with intrauterine inflammation-induced oxidative stress in a mouse model","volume":"67","author":"Lee","year":"2019","journal-title":"J Pineal Res"},{"key":"10.1016\/j.jare.2024.02.014_b0195","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2023.13101","article-title":"Melatonin alleviates renal injury in diabetic rats by regulating autophagy","volume":"28","author":"Luo","year":"2023","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.jare.2024.02.014_b0200","doi-asserted-by":"crossref","first-page":"10","DOI":"10.14806\/ej.17.1.200","article-title":"Cutadapt removes adapter sequences from high-throughput sequencing reads","volume":"17","author":"Martin","year":"2011","journal-title":"EMBnet J"},{"key":"10.1016\/j.jare.2024.02.014_b0205","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1093\/bioinformatics\/btr507","article-title":"FLASH: fast length adjustment of short reads to improve genome assemblies","volume":"27","author":"Mago\u010d","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jare.2024.02.014_b0210","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/s41587-019-0209-9","article-title":"Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2","volume":"37","author":"Bolyen","year":"2019","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.jare.2024.02.014_b0215","article-title":"Greengenes2 unifies microbial data in a single reference tree","author":"McDonald","year":"2023","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.jare.2024.02.014_b0220","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2011-12-6-r60","article-title":"Metagenomic biomarker discovery and explanation","volume":"12","author":"Segata","year":"2011","journal-title":"Genome Biol"},{"key":"10.1016\/j.jare.2024.02.014_b0225","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.immuni.2018.05.009","article-title":"Critical role for the microbiota in CX(3)CR1(+) intestinal mononuclear phagocyte regulation of intestinal T cell responses","volume":"49","author":"Kim","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.jare.2024.02.014_b0230","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40168-023-01535-9","article-title":"The hindgut microbiome contributes to host oxidative stress in postpartum dairy cows by affecting glutathione synthesis process","volume":"11","author":"Gu","year":"2023","journal-title":"Microbiome"},{"key":"10.1016\/j.jare.2024.02.014_b0235","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2018.03289","article-title":"Comparative evaluation of microbiota engraftment following fecal microbiota transfer in mice models: age, kinetic and microbial status matter","volume":"9","author":"Le Roy","year":"2019","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jare.2024.02.014_b0240","doi-asserted-by":"crossref","first-page":"426","DOI":"10.3109\/14767058.2014.918600","article-title":"Dose-dependent sickness behavior, abortion and inflammation induced by systemic LPS injection in pregnant mice","volume":"28","author":"Toyama","year":"2015","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.jare.2024.02.014_b0245","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.tox.2007.02.010","article-title":"Effects of low-dose lipopolysaccharide (LPS) pretreatment on LPS-induced intra-uterine fetal death and preterm labor","volume":"234","author":"Xu","year":"2007","journal-title":"Toxicology"},{"key":"10.1016\/j.jare.2024.02.014_b0250","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.642071","article-title":"Stimulation of \u03b17 nicotinic acetylcholine receptor by nicotine suppresses decidual M1 macrophage polarization against inflammation in lipopolysaccharide-induced preeclampsia-like mouse model","volume":"12","author":"Han","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.jare.2024.02.014_b0255","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1002\/fft2.238","article-title":"Gymnema sylvestre extract ameliorated streptozotocin-induced hyperglycemia in T2DM rats via gut microbiota","volume":"4","author":"Chen","year":"2023","journal-title":"Food Front"},{"key":"10.1016\/j.jare.2024.02.014_b0260","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1051\/rnd:2000105","article-title":"Uterine blood flow in sows: effects of pregnancy stage and litter size","volume":"40","author":"P\u00e8re","year":"2000","journal-title":"Reprod Nutr Dev"},{"key":"10.1016\/j.jare.2024.02.014_b0265","doi-asserted-by":"crossref","first-page":"66","DOI":"10.21451\/1984-3143-AR2018-0127","article-title":"Intrauterine growth restriction: screening and diagnosis using animal models","volume":"16","author":"Felicioni","year":"2020","journal-title":"Anim Reprod"},{"key":"10.1016\/j.jare.2024.02.014_b0270","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.reprotox.2016.06.010","article-title":"Maternal cadmium exposure reduces placental zinc transport and induces fetal growth restriction in mice","volume":"63","author":"Wang","year":"2016","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.jare.2024.02.014_b0275","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1007\/s11325-021-02529-3","article-title":"Gestational chronic intermittent hypoxia induces hypertension, proteinuria, and fetal growth restriction in mice","volume":"26","author":"Weng","year":"2022","journal-title":"Sleep Breath"},{"key":"10.1016\/j.jare.2024.02.014_b0280","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1136\/gutjnl-2020-323347","article-title":"Disrupted spermatogenesis in a metabolic syndrome model: the role of vitamin A metabolism in the gut-testis axis","volume":"71","author":"Zhang","year":"2022","journal-title":"Gut"},{"key":"10.1016\/j.jare.2024.02.014_b0285","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1007\/s00018-020-03656-y","article-title":"TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling","volume":"78","author":"Ciesielska","year":"2021","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.jare.2024.02.014_b0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.131816","article-title":"Mitigation of maternal fecal microbiota transplantation on neurobehavioral deficits of offspring rats prenatally exposed to arsenic: role of microbiota-gut-brain axis","volume":"457","author":"Zhao","year":"2023","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jare.2024.02.014_b0295","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.placenta.2022.03.007","article-title":"Low-dose aspirin prevents LPS-induced preeclampsia-like phenotype via AQP-1 and the MAPK\/ERK 1\/2 pathway","volume":"121","author":"Zhang","year":"2022","journal-title":"Placenta"},{"key":"10.1016\/j.jare.2024.02.014_b0300","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1016\/j.jtcvs.2022.04.005","article-title":"Steen solution protects pulmonary microvascular endothelial cells and preserves endothelial barrier after lipopolysaccharide-induced injury","volume":"165","author":"Ta","year":"2023","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jare.2024.02.014_b0305","doi-asserted-by":"crossref","DOI":"10.3390\/biom9110735","article-title":"Role of reactive oxygen species in cancer progression: molecular mechanisms and recent advancements","volume":"9","author":"Aggarwal","year":"2019","journal-title":"Biomolecules"},{"key":"10.1016\/j.jare.2024.02.014_b0310","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1159\/000444526","article-title":"R-Ras inhibits VEGF-induced p38MAPK activation and HSP27 phosphorylation in endothelial cells","volume":"52","author":"Sawada","year":"2015","journal-title":"J Vasc Res"},{"key":"10.1016\/j.jare.2024.02.014_b0315","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.670980","article-title":"Mechanistic target of rapamycin complex 2 regulation of the primary human trophoblast cell transcriptome","volume":"9","author":"Rosario","year":"2021","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.jare.2024.02.014_b0320","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/nature18307","article-title":"Paris Agreement climate proposals need a boost to keep warming well below 2 \u00b0C","volume":"534","author":"Rogelj","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.jare.2024.02.014_b0325","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-022-29613-w","article-title":"Solar geoengineering could redistribute malaria risk in developing countries","volume":"13","author":"Carlson","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.jare.2024.02.014_b0330","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-023-37554-1","article-title":"The most at-risk regions in the world for high-impact heatwaves","volume":"14","author":"Thompson","year":"2023","journal-title":"Nat Commun"},{"key":"10.1016\/j.jare.2024.02.014_b0335","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2022.686902","article-title":"Heat stress-induced dysbiosis of porcine colon microbiota plays a role in intestinal damage: a fecal microbiota profile","volume":"9","author":"Hu","year":"2022","journal-title":"Front Vet Sci"},{"key":"10.1016\/j.jare.2024.02.014_b0340","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1113\/JP277353","article-title":"High-fat diet intake modulates maternal intestinal adaptations to pregnancy and results in placental hypoxia, as well as altered fetal gut barrier proteins and immune markers","volume":"597","author":"Gohir","year":"2019","journal-title":"J Physiol"},{"key":"10.1016\/j.jare.2024.02.014_b0345","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.8243","article-title":"Association of air pollution and heat exposure with preterm birth, low birth weight, and stillbirth in the US: a systematic review","volume":"3","author":"Bekkar","year":"2020","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.jare.2024.02.014_b0350","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2021.101854","article-title":"Melatonin protects against environmental stress-induced fetal growth restriction via suppressing ROS-mediated GCN2\/ATF4\/BNIP3-dependent mitophagy in placental trophoblasts","volume":"40","author":"Zhu","year":"2021","journal-title":"Redox Biol"},{"key":"10.1016\/j.jare.2024.02.014_b0355","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.160041","article-title":"Reducing light exposure enhances the circadian rhythm of the biological clock through interactions with the gut microbiota","volume":"858","author":"Zhang","year":"2023","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.jare.2024.02.014_b0360","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2019.01030","article-title":"LPS induces preeclampsia-like phenotype in rats and HTR8\/SVneo cells dysfunction through TLR4\/p38 MAPK pathway","volume":"10","author":"Fan","year":"2019","journal-title":"Front Physiol"},{"key":"10.1016\/j.jare.2024.02.014_b0365","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-21072-y","article-title":"Galectin-3 plays an important role in preterm birth caused by dental infection of Porphyromonas gingivalis","volume":"8","author":"Miyauchi","year":"2018","journal-title":"Sci Rep"}],"container-title":["Journal of Advanced Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123224000766?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123224000766?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T08:56:41Z","timestamp":1778835401000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2090123224000766"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":73,"alternative-id":["S2090123224000766"],"URL":"https:\/\/doi.org\/10.1016\/j.jare.2024.02.014","relation":{},"ISSN":["2090-1232"],"issn-type":[{"value":"2090-1232","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Melatonin alleviates high temperature exposure induced fetal growth restriction via the gut-placenta-fetus axis in pregnant mice","name":"articletitle","label":"Article Title"},{"value":"Journal of Advanced Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jare.2024.02.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Production and hosting by Elsevier B.V. on behalf of Cairo University","name":"copyright","label":"Copyright"}]}}