{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:53:38Z","timestamp":1790816018020,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T00:00:00Z","timestamp":1723680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","award":["2018ZX09734003"],"award-info":[{"award-number":["2018ZX09734003"]}],"id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004000","name":"Guangzhou Science and Technology Program Key Projects","doi-asserted-by":"publisher","award":["201804010485"],"award-info":[{"award-number":["201804010485"]}],"id":[{"id":"10.13039\/501100004000","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82073917"],"award-info":[{"award-number":["82073917"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81872902"],"award-info":[{"award-number":["81872902"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82300217"],"award-info":[{"award-number":["82300217"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Research"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.jare.2024.08.023","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T19:27:27Z","timestamp":1724095647000},"page":"631-644","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Dialog between mantle cell lymphoma cells and lymphoma-associated macrophages underlies ibrutinib resistance"],"prefix":"10.1016","volume":"73","author":[{"given":"Xiaoqing","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caiqin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianghua","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianqiu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajia","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Peter Gale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jare.2024.08.023_b0005","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1093\/annonc\/mdv111","article-title":"Patients with mantle cell lymphoma failing ibrutinib are unlikely to respond to salvage chemotherapy and have poor outcomes","volume":"26","author":"Cheah","year":"2015","journal-title":"Ann Oncol"},{"key":"10.1016\/j.jare.2024.08.023_b0010","doi-asserted-by":"crossref","unstructured":"Saleh K, Cheminant M, Chiron D, Burroni B, Ribrag V, Sarkozy C. Tumor Microenvironment and Immunotherapy-Based Approaches in Mantle Cell Lymphoma. Cancers (Basel) 2022;14.DOI: 10.3390\/cancers14133229.","DOI":"10.3390\/cancers14133229"},{"key":"10.1016\/j.jare.2024.08.023_b0015","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/s12943-023-01805-y","article-title":"Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer","volume":"22","author":"Ye","year":"2023","journal-title":"Mol Cancer"},{"key":"10.1016\/j.jare.2024.08.023_b0020","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1158\/2159-8290.CD-16-0850","article-title":"Overcoming the immunosuppressive tumor microenvironment of hodgkin lymphoma using chimeric antigen receptor T Cells","volume":"7","author":"Ruella","year":"2017","journal-title":"Cancer Discov"},{"key":"10.1016\/j.jare.2024.08.023_b0025","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22136995","article-title":"Macrophage Polarization States in the Tumor Microenvironment","volume":"22","author":"Boutilier","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jare.2024.08.023_b0030","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1080\/21645515.2015.1009814","article-title":"Clinically feasible approaches to potentiating cancer cell-based immunotherapies","volume":"11","author":"Seledtsov","year":"2015","journal-title":"Hum Vaccin Immunother"},{"key":"10.1016\/j.jare.2024.08.023_b0035","article-title":"CC chemokines in a tumor: a review of pro-cancer and anti-cancer properties of the ligands of receptors CCR1, CCR2, CCR3, and CCR4","volume":"21","author":"Korbecki","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jare.2024.08.023_b0040","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/cac2.12010","article-title":"CXCL5\/CXCR2 axis in tumor microenvironment as potential diagnostic biomarker and therapeutic target","volume":"40","author":"Zhang","year":"2020","journal-title":"Cancer Commun (Lond)"},{"key":"10.1016\/j.jare.2024.08.023_b0045","doi-asserted-by":"crossref","first-page":"6735","DOI":"10.1158\/1078-0432.CCR-07-4843","article-title":"The interleukin-8 pathway in cancer","volume":"14","author":"Waugh","year":"2008","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.jare.2024.08.023_b0050","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1186\/s12935-022-02717-5","article-title":"Crosstalk between tumor-associated macrophages and tumor cells promotes chemoresistance via CXCL5\/PI3K\/AKT\/mTOR pathway in gastric cancer","volume":"22","author":"Su","year":"2022","journal-title":"Cancer Cell Int"},{"key":"10.1016\/j.jare.2024.08.023_b0055","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1161\/ATVBAHA.111.225508","article-title":"C-reactive protein polarizes human macrophages to an M1 phenotype and inhibits transformation to the M2 phenotype","volume":"31","author":"Devaraj","year":"2011","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jare.2024.08.023_b0060","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s41556-021-00818-3","article-title":"PKC\u03b2II phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis","volume":"24","author":"Zhang","year":"2022","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.jare.2024.08.023_b0065","doi-asserted-by":"crossref","first-page":"15208","DOI":"10.1038\/ncomms15208","article-title":"Senescent tumor cells lead the collective invasion in thyroid cancer","volume":"8","author":"Kim","year":"2017","journal-title":"Nat Commun"},{"key":"10.1016\/j.jare.2024.08.023_b0070","doi-asserted-by":"crossref","first-page":"G22","DOI":"10.1152\/ajpgi.00229.2017","article-title":"Macrophage depletion using clodronate liposomes decreases tumorigenesis and alters gut microbiota in the AOM\/DSS mouse model of colon cancer","volume":"314","author":"Bader","year":"2018","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.jare.2024.08.023_b0075","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/s41591-018-0243-z","article-title":"Dynamic molecular monitoring reveals that SWI-SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma","volume":"25","author":"Agarwal","year":"2019","journal-title":"Nat Med"},{"key":"10.1016\/j.jare.2024.08.023_b0080","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nm.3435","article-title":"Pharmacological and genomic profiling identifies NF-\u03baB-targeted treatment strategies for mantle cell lymphoma","volume":"20","author":"Rahal","year":"2014","journal-title":"Nat Med"},{"key":"10.1016\/j.jare.2024.08.023_b0085","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241713287","article-title":"Bioinformatic analysis of the CXCR2 ligands in cancer processes","volume":"24","author":"Korbecki","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jare.2024.08.023_b0090","doi-asserted-by":"crossref","first-page":"5122","DOI":"10.1038\/onc.2017.108","article-title":"A positive crosstalk between CXCR4 and CXCR2 promotes gastric cancer metastasis","volume":"36","author":"Xiang","year":"2017","journal-title":"Oncogene"},{"key":"10.1016\/j.jare.2024.08.023_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2019.165551","article-title":"Chronic inhibition of chemokine receptor CXCR2 attenuates cardiac remodeling and dysfunction in spontaneously hypertensive rats","volume":"1865","author":"Zhang","year":"2019","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"10.1016\/j.jare.2024.08.023_b0100","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1038\/onc.2016.367","article-title":"CXCL2\/MIF-CXCR2 signaling promotes the recruitment of myeloid-derived suppressor cells and is correlated with prognosis in bladder cancer","volume":"36","author":"Zhang","year":"2017","journal-title":"Oncogene"},{"key":"10.1016\/j.jare.2024.08.023_b0105","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/s41389-020-00249-z","article-title":"CXCL5 promotes gastric cancer metastasis by inducing epithelial-mesenchymal transition and activating neutrophils","volume":"9","author":"Mao","year":"2020","journal-title":"Oncogenesis"},{"key":"10.1016\/j.jare.2024.08.023_b0110","article-title":"Modified Bushen Yiqi Formula mitigates pulmonary inflammation and airway remodeling by inhibiting neutrophils chemotaxis and IL17 signaling pathway in rats with COPD","volume":"321","author":"Kong","year":"2023","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.jare.2024.08.023_b0115","unstructured":"Johnson P et al. 2019 ASH abstract 354. 2019:"},{"key":"10.1016\/j.jare.2024.08.023_b0120","doi-asserted-by":"crossref","first-page":"2442","DOI":"10.1038\/s41375-019-0463-3","article-title":"CSF1R and BTK inhibitions as novel strategies to disrupt the dialog between mantle cell lymphoma and macrophages","volume":"33","author":"Papin","year":"2019","journal-title":"Leukemia"},{"key":"10.1016\/j.jare.2024.08.023_b0125","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a021857","article-title":"CSF-1 receptor signaling in myeloid cells","volume":"6","author":"Stanley","year":"2014","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"10.1016\/j.jare.2024.08.023_b0130","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1111\/his.12407","article-title":"High intratumoral macrophage content is an adverse prognostic feature in anaplastic large cell lymphoma","volume":"65","author":"Pedersen","year":"2014","journal-title":"Histopathology"},{"key":"10.1016\/j.jare.2024.08.023_b0135","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1158\/1535-7163.MCT-20-0591","article-title":"CSF1\/CSF1R Signaling Inhibitor Pexidartinib (PLX3397) Reprograms Tumor-Associated Macrophages and Stimulates T-cell Infiltration in the Sarcoma Microenvironment","volume":"20","author":"Fujiwara","year":"2021","journal-title":"Mol Cancer Ther"},{"key":"10.1016\/j.jare.2024.08.023_b0140","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2022-005610","article-title":"Silence of a dependence receptor CSF1R in colorectal cancer cells activates tumor-associated macrophages","volume":"10","author":"Zhu","year":"2022","journal-title":"J Immunother Cancer"},{"key":"10.1016\/j.jare.2024.08.023_b0145","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1038\/s41419-019-1837-1","article-title":"CXCR2 expression on granulocyte and macrophage progenitors under tumor conditions contributes to mo-MDSC generation via SAP18\/ERK\/STAT3","volume":"10","author":"Han","year":"2019","journal-title":"Cell Death Dis"}],"container-title":["Journal of Advanced Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123224003667?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123224003667?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T10:52:56Z","timestamp":1762599176000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2090123224003667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":29,"alternative-id":["S2090123224003667"],"URL":"https:\/\/doi.org\/10.1016\/j.jare.2024.08.023","relation":{},"ISSN":["2090-1232"],"issn-type":[{"value":"2090-1232","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dialog between mantle cell lymphoma cells and lymphoma-associated macrophages underlies ibrutinib resistance","name":"articletitle","label":"Article Title"},{"value":"Journal of Advanced Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jare.2024.08.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V. on behalf of Cairo University.","name":"copyright","label":"Copyright"}]}}