{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:46:31Z","timestamp":1789519591101,"version":"build-2803163510"},"reference-count":141,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T00:00:00Z","timestamp":1731369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Research"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.jare.2024.11.022","type":"journal-article","created":{"date-parts":[[2024,11,17]],"date-time":"2024-11-17T15:47:58Z","timestamp":1731858478000},"page":"119-133","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Transient receptor potential channels in viral infectious diseases: Biological characteristics and regulatory mechanisms"],"prefix":"10.1016","volume":"76","author":[{"given":"Wen-Hui","family":"Qi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Jing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2463-8298","authenticated-orcid":false,"given":"Xiao-Qiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6571","key":"10.1016\/j.jare.2024.11.022_b0005","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1126\/science.abj7965","article-title":"Mechanisms of viral inflammation and disease in humans","volume":"374","author":"Casanova","year":"2021","journal-title":"Science (New York, NY)"},{"issue":"3","key":"10.1016\/j.jare.2024.11.022_b0010","doi-asserted-by":"crossref","DOI":"10.1128\/MMBR.00053-21","article-title":"The baltimore classification of viruses 50 years later: How does it stand in the light of virus evolution?","volume":"85","author":"Koonin","year":"2021","journal-title":"Microbiol Mol Biol Rev"},{"issue":"6","key":"10.1016\/j.jare.2024.11.022_b0015","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1016\/j.cell.2021.02.013","article-title":"Antivirals with common targets against highly pathogenic viruses","volume":"184","author":"Lu","year":"2021","journal-title":"Cell"},{"issue":"11","key":"10.1016\/j.jare.2024.11.022_b0020","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1016\/j.cmi.2022.02.023","article-title":"Genetic susceptibility to viral disease in humans","volume":"28","author":"Mogensen","year":"2022","journal-title":"Clin Microbiol Infect"},{"issue":"7504","key":"10.1016\/j.jare.2024.11.022_b0025","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1136\/bmj.330.7504.1341","article-title":"Highly active antiretroviral therapy","volume":"330","author":"Moerman","year":"2005","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0030","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/s41591-021-01643-9","article-title":"A guide to immunotherapy for COVID-19","volume":"28","author":"van de Veerdonk","year":"2022","journal-title":"Nat Med"},{"issue":"5","key":"10.1016\/j.jare.2024.11.022_b0035","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/0092-8674(95)90180-9","article-title":"Calcium ions as extracellular messengers","volume":"83","author":"Brown","year":"1995","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0040","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1146\/annurev-virology-100114-054846","article-title":"Pathophysiological consequences of calcium-conducting viroporins","volume":"2","author":"Hyser","year":"2015","journal-title":"Annu Rev Virol"},{"issue":"6298","key":"10.1016\/j.jare.2024.11.022_b0045","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/348192a0","article-title":"Calcium channels. Gating for the physiologist","volume":"348","author":"Bean","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.jare.2024.11.022_b0050","doi-asserted-by":"crossref","unstructured":"Wu L J, Sweet T B and Clapham D E. International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family. Pharmacol Rev. 2010; 62(3): 381-404.","DOI":"10.1124\/pr.110.002725"},{"issue":"5","key":"10.1016\/j.jare.2024.11.022_b0055","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/S0092-8674(02)00670-0","article-title":"The TRP channels, a remarkably functional family","volume":"108","author":"Montell","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.jare.2024.11.022_b0060","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1146\/annurev-pharmtox-010617-052832","article-title":"TRP channels as potential drug targets","volume":"58","author":"Moran","year":"2018","journal-title":"Annu Rev Pharmacol Toxicol"},{"issue":"5216","key":"10.1016\/j.jare.2024.11.022_b0065","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/224285a0","article-title":"Abnormal electroretinogram from a Drosophila mutant","volume":"224","author":"Cosens","year":"1969","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0070","doi-asserted-by":"crossref","DOI":"10.3390\/cells9010094","article-title":"Host calcium channels and pumps in viral infections","volume":"9","author":"Chen","year":"2019","journal-title":"Cells"},{"issue":"2","key":"10.1016\/j.jare.2024.11.022_b0075","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1152\/physrev.00001.2002","article-title":"TRP channel proteins and signal transduction","volume":"82","author":"Minke","year":"2002","journal-title":"Physiol Rev"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0080","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/s41573-021-00268-4","article-title":"Advances in TRP channel drug discovery: From target validation to clinical studies","volume":"21","author":"Koivisto","year":"2022","journal-title":"Nat Rev Drug Discov"},{"issue":"5530","key":"10.1016\/j.jare.2024.11.022_b0085","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/258084a0","article-title":"Induction of photoreceptor voltage noise in the dark in Drosophila mutant","volume":"258","author":"Minke","year":"1975","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.jare.2024.11.022_b0090","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.1073\/pnas.96.5.2060","article-title":"Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative Ca2+ entry channel","volume":"96","author":"Vannier","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jare.2024.11.022_b0095","doi-asserted-by":"crossref","unstructured":"Storch U, Forst A L, Philipp M, Gudermann T, and Mederos y Schnitzler M. Transient receptor potential channel 1 (TRPC1) reduces calcium permeability in heteromeric channel complexes. J Biol Chem. 2012; 287(5): 3530-3540.","DOI":"10.1074\/jbc.M111.283218"},{"issue":"9","key":"10.1016\/j.jare.2024.11.022_b0100","doi-asserted-by":"crossref","DOI":"10.3390\/cells9091983","article-title":"Transient Receptor Potential Canonical (TRPC) channels: Then and now","volume":"9","author":"Chen","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.jare.2024.11.022_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2022.106262","article-title":"TRPC1 contributes to endotoxemia-induced myocardial dysfunction via mediating myocardial apoptosis and autophagy","volume":"181","author":"Tian","year":"2022","journal-title":"Pharmacol Res"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0110","doi-asserted-by":"crossref","first-page":"7455","DOI":"10.1038\/s41467-022-35242-0","article-title":"TRPC channels blockade abolishes endotoxemic cardiac dysfunction by hampering intracellular inflammation and Ca(2+) leakage","volume":"13","author":"Tang","year":"2022","journal-title":"Nat Commun"},{"issue":"S3","key":"10.1016\/j.jare.2024.11.022_b0115","doi-asserted-by":"crossref","first-page":"108","DOI":"10.33594\/000000358","article-title":"Beyond hot and spicy: TRPV channels and their pharmacological modulation","volume":"55","author":"Seebohm","year":"2021","journal-title":"Cell Physiol Biochem"},{"issue":"17","key":"10.1016\/j.jare.2024.11.022_b0120","doi-asserted-by":"crossref","first-page":"2192","DOI":"10.2174\/156802611796904834","article-title":"Disease-related changes in TRPV1 expression and its implications for drug development","volume":"11","author":"Premkumar","year":"2011","journal-title":"Curr Top Med Chem"},{"key":"10.1016\/j.jare.2024.11.022_b0125","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/978-3-642-54215-2_23","article-title":"TRPA1","volume":"222","author":"Zygmunt","year":"2014","journal-title":"Handb Exp Pharmacol"},{"issue":"4","key":"10.1016\/j.jare.2024.11.022_b0130","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1073\/pnas.0808487106","article-title":"TRPA1 acts as a cold sensor in vitro and in vivo","volume":"106","author":"Karashima","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"44","key":"10.1016\/j.jare.2024.11.022_b0135","doi-asserted-by":"crossref","first-page":"38168","DOI":"10.1074\/jbc.M111.288993","article-title":"Molecular architecture and subunit organization of TRPA1 ion channel revealed by electron microscopy","volume":"286","author":"Cvetkov","year":"2011","journal-title":"J Biol Chem"},{"issue":"70","key":"10.1016\/j.jare.2024.11.022_b0140","doi-asserted-by":"crossref","first-page":"ra21","DOI":"10.1126\/scisignal.2000146","article-title":"TRPM1 forms ion channels associated with melanin content in melanocytes","volume":"2","author":"Oancea","year":"2009","journal-title":"Sci Signal"},{"issue":"5","key":"10.1016\/j.jare.2024.11.022_b0145","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1007\/s00432-019-02898-z","article-title":"TRPM2 mediates distruption of autophagy machinery and correlates with the grade level in prostate cancer","volume":"145","author":"Tektemur","year":"2019","journal-title":"J Cancer Res Clin Oncol"},{"issue":"10","key":"10.1016\/j.jare.2024.11.022_b0150","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1016\/j.dld.2020.05.027","article-title":"TRPM7 is overexpressed in human IBD-related and sporadic colorectal cancer and correlates with tumor grade","volume":"52","author":"Pugliese","year":"2020","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.jare.2024.11.022_b0155","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3390\/cells9122604","article-title":"TRPM channels in human diseases","volume":"9","author":"Jimenez","year":"2020","journal-title":"Cells"},{"issue":"8","key":"10.1016\/j.jare.2024.11.022_b0160","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.bbadis.2007.01.004","article-title":"TRPML and lysosomal function","volume":"1772","author":"Zeevi","year":"2007","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.jare.2024.11.022_b0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/biom11010065","article-title":"Endolysosomal TRPMLs in cancer","volume":"11","author":"Xu","year":"2021","journal-title":"Biomolecules"},{"issue":"6","key":"10.1016\/j.jare.2024.11.022_b0170","first-page":"650","article-title":"TRPP subfamily and kidney diseases","volume":"39","author":"Zhao","year":"2010","journal-title":"Zhejiang Da Xue Xue Bao Yi Xue Ban"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0175","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s00424-005-1469-4","article-title":"Cellular and molecular function of mucolipins (TRPML) and polycystin 2 (TRPP2)","volume":"451","author":"Qian","year":"2005","journal-title":"Pflugers Arch"},{"issue":"8","key":"10.1016\/j.jare.2024.11.022_b0180","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1042\/BC20100152","article-title":"Remodelling of the endoplasmic reticulum during store-operated calcium entry","volume":"103","author":"Shen","year":"2011","journal-title":"Biol Cell"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0185","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/s41392-023-01464-x","article-title":"TRP (transient receptor potential) ion channel family: Structures, biological functions and therapeutic interventions for diseases","volume":"8","author":"Zhang","year":"2023","journal-title":"Signal Transduct Target Ther"},{"issue":"3","key":"10.1016\/j.jare.2024.11.022_b0190","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s40256-018-00320-6","article-title":"Clinical pharmacokinetics, safety, and tolerability of a novel, first-in-class TRPV4 ion channel inhibitor, GSK2798745, in healthy and heart failure subjects","volume":"19","author":"Goyal","year":"2019","journal-title":"Am J Cardiovasc Drugs"},{"key":"10.1016\/j.jare.2024.11.022_b0195","doi-asserted-by":"crossref","unstructured":"Li T, Jiang S, Ni B, et al. Discontinued Drugs for the Treatment of Cardiovascular Disease from 2016 to 2018. Int J Mol Sci. 2019; 20(18).","DOI":"10.3390\/ijms20184513"},{"issue":"17","key":"10.1016\/j.jare.2024.11.022_b0200","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.7150\/jca.20639","article-title":"Inhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft model","volume":"9","author":"Xue","year":"2018","journal-title":"J Cancer"},{"issue":"3","key":"10.1016\/j.jare.2024.11.022_b0205","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1007\/s10637-017-0438-z","article-title":"First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors","volume":"35","author":"Fu","year":"2017","journal-title":"Invest New Drugs"},{"issue":"20","key":"10.1016\/j.jare.2024.11.022_b0210","doi-asserted-by":"crossref","first-page":"3845","DOI":"10.1523\/JNEUROSCI.3048-18.2019","article-title":"A human TRPA1-specific pain model","volume":"39","author":"Heber","year":"2019","journal-title":"J Neurosci"},{"issue":"6","key":"10.1016\/j.jare.2024.11.022_b0215","doi-asserted-by":"crossref","first-page":"e738","DOI":"10.1097\/j.pain.0000000000002470","article-title":"Randomized, double-blind, placebo-controlled trial of ISC 17536, an oral inhibitor of transient receptor potential ankyrin 1, in patients with painful diabetic peripheral neuropathy: impact of preserved small nerve fiber function","volume":"163","author":"Jain","year":"2022","journal-title":"Pain"},{"issue":"5","key":"10.1016\/j.jare.2024.11.022_b0220","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1002\/cpt.3024","article-title":"TRPA1 antagonist LY3526318 inhibits the cinnamaldehyde-evoked dermal blood flow increase: Translational proof of pharmacology","volume":"114","author":"Bamps","year":"2023","journal-title":"Clin Pharmacol Ther"},{"issue":"12","key":"10.1016\/j.jare.2024.11.022_b0225","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1007\/s40263-023-01042-3","article-title":"Effect of BI 1358894 on cholecystokinin-tetrapeptide (CCK-4)-induced anxiety, panic symptoms, and stress biomarkers: A phase I randomized trial in healthy males","volume":"37","author":"Goettel","year":"2023","journal-title":"CNS Drugs"},{"issue":"18","key":"10.1016\/j.jare.2024.11.022_b0230","doi-asserted-by":"crossref","first-page":"3723","DOI":"10.1111\/bph.14777","article-title":"Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes","volume":"176","author":"Nishiyama","year":"2019","journal-title":"Br J Pharmacol"},{"issue":"4","key":"10.1016\/j.jare.2024.11.022_b0235","doi-asserted-by":"crossref","DOI":"10.1002\/jmv.29510","article-title":"TRPV4 promotes HBV replication and capsid assembly via methylation modification of H3K4 and HBc ubiquitin","volume":"96","author":"Zhang","year":"2024","journal-title":"J Med Virol"},{"key":"10.1016\/j.jare.2024.11.022_b0240","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.coviro.2021.08.003","article-title":"Molecular dynamics of the viral life cycle: Progress and prospects","volume":"50","author":"Jones","year":"2021","journal-title":"Curr Opin Virol"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0245","doi-asserted-by":"crossref","DOI":"10.3390\/cells9010126","article-title":"TRPC channels in the SOCE scenario","volume":"9","author":"Lopez","year":"2020","journal-title":"Cells"},{"issue":"2","key":"10.1016\/j.jare.2024.11.022_b0250","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.ceca.2007.03.004","article-title":"TRPC channels as STIM1-regulated store-operated channels","volume":"42","author":"Worley","year":"2007","journal-title":"Cell Calcium"},{"issue":"12","key":"10.1016\/j.jare.2024.11.022_b0255","doi-asserted-by":"crossref","first-page":"eaaz3367","DOI":"10.1126\/sciadv.aaz3367","article-title":"TRPC1 participates in the HSV-1 infection process by facilitating viral entry","volume":"6","author":"He","year":"2020","journal-title":"Sci Adv"},{"key":"10.1016\/j.jare.2024.11.022_b0260","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/978-3-642-54215-2_2","article-title":"TRPC1","volume":"222","author":"Nesin","year":"2014","journal-title":"Handb Exp Pharmacol"},{"key":"10.1016\/j.jare.2024.11.022_b0265","article-title":"Clinical characteristics of 113 deceased patients with coronavirus disease 2019: Retrospective study","volume":"368","author":"Chen","year":"2020","journal-title":"BMJ"},{"issue":"5","key":"10.1016\/j.jare.2024.11.022_b0270","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.1002\/jmv.26750","article-title":"Predictors of mortality in 217 COVID-19 patients in Northwest Ohio, United States: A retrospective study","volume":"93","author":"Merugu","year":"2021","journal-title":"J Med Virol"},{"issue":"3","key":"10.1016\/j.jare.2024.11.022_b0275","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.cmi.2020.11.005","article-title":"Neurologic manifestations associated with COVID-19: a multicentre registry","volume":"27","author":"Meppiel","year":"2021","journal-title":"Clin Microbiol Infect"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0280","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24010102","article-title":"TRPC3-Nox2 protein complex formation increases the risk of SARS-CoV-2 spike protein-induced cardiomyocyte dysfunction through ACE2 upregulation","volume":"24","author":"Kato","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"15","key":"10.1016\/j.jare.2024.11.022_b0285","doi-asserted-by":"crossref","first-page":"7379","DOI":"10.7150\/thno.58781","article-title":"TRPV2-spike protein interaction mediates the entry of SARS-CoV-2 into macrophages in febrile conditions","volume":"11","author":"Xu","year":"2021","journal-title":"Theranostics"},{"issue":"9","key":"10.1016\/j.jare.2024.11.022_b0290","doi-asserted-by":"crossref","first-page":"C881","DOI":"10.1152\/ajpcell.00182.2012","article-title":"Involvement of TRPV2 and SOCE in calcium influx disorder in DMD primary human myotubes with a specific contribution of \u03b11-syntrophin and PLC\/PKC in SOCE regulation","volume":"304","author":"Harisseh","year":"2013","journal-title":"Am J Physiol Cell Physiol"},{"issue":"34","key":"10.1016\/j.jare.2024.11.022_b0295","article-title":"The transient receptor potential vanilloid 2 (TRPV2) channel facilitates virus infection through the Ca(2+) -LRMDA axis in myeloid cells","volume":"9","author":"Guo","year":"2022","journal-title":"Adv Sci (Weinh)"},{"key":"10.1016\/j.jare.2024.11.022_b0300","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.78840","article-title":"Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion","volume":"11","author":"Zhang","year":"2022","journal-title":"Elife"},{"key":"10.1016\/j.jare.2024.11.022_b0305","doi-asserted-by":"crossref","first-page":"739","DOI":"10.3389\/fimmu.2020.00739","article-title":"Involvement of the TRPML mucolipin channels in viral infections and anti-viral innate immune responses","volume":"11","author":"Santoni","year":"2020","journal-title":"Front Immunol"},{"issue":"4","key":"10.1016\/j.jare.2024.11.022_b0310","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1080\/15548627.2022.2116676","article-title":"A plant virus hijacks phosphatidylinositol-3,5-bisphosphate to escape autophagic degradation in its insect vector","volume":"19","author":"Wang","year":"2023","journal-title":"Autophagy"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0315","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02314-17","article-title":"Mucolipin-2 cation channel increases trafficking efficiency of endocytosed viruses","volume":"9","author":"Rinkenberger","year":"2018","journal-title":"MBio"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0320","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1080\/22221751.2021.1941276","article-title":"Berbamine inhibits Japanese encephalitis virus (JEV) infection by compromising TPRMLs-mediated endolysosomal trafficking of low-density lipoprotein receptor (LDLR)","volume":"10","author":"Huang","year":"2021","journal-title":"Emerg Microbes Infect"},{"key":"10.1016\/j.jare.2024.11.022_b0325","doi-asserted-by":"crossref","DOI":"10.1016\/j.antiviral.2020.104922","article-title":"ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity","volume":"182","author":"Xia","year":"2020","journal-title":"Antiviral Res"},{"key":"10.1016\/j.jare.2024.11.022_b0330","doi-asserted-by":"crossref","DOI":"10.1016\/j.antiviral.2021.105193","article-title":"ML-SA1 and SN-2 inhibit endocytosed viruses through regulating TRPML channel expression and activity","volume":"195","author":"Xia","year":"2021","journal-title":"Antiviral Res"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0335","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1083\/jcb.137.1.93","article-title":"Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cells","volume":"137","author":"Rodr\u00edguez","year":"1997","journal-title":"J Cell Biol"},{"issue":"6","key":"10.1016\/j.jare.2024.11.022_b0340","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.cell.2015.05.009","article-title":"A TRP channel senses lysosome neutralization by pathogens to trigger their expulsion","volume":"161","author":"Miao","year":"2015","journal-title":"Cell"},{"issue":"23","key":"10.1016\/j.jare.2024.11.022_b0345","doi-asserted-by":"crossref","first-page":"3250","DOI":"10.1016\/j.devcel.2021.10.006","article-title":"ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress","volume":"56","author":"Chen","year":"2021","journal-title":"Dev Cell"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0350","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1080\/21505594.2019.1605803","article-title":"The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections","volume":"10","author":"Mehrbod","year":"2019","journal-title":"Virulence"},{"issue":"8","key":"10.1016\/j.jare.2024.11.022_b0355","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1111\/jvh.13710","article-title":"TRPM2 regulates autophagy to participate in hepatitis B virus replication","volume":"29","author":"Chen","year":"2022","journal-title":"J Viral Hepat"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0360","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1136\/thoraxjnl-2013-203894","article-title":"Rhinovirus upregulates transient receptor potential channels in a human neuronal cell line: Implications for respiratory virus-induced cough reflex sensitivity","volume":"69","author":"Abdullah","year":"2014","journal-title":"Thorax"},{"key":"10.1016\/j.jare.2024.11.022_b0365","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1171275","article-title":"Coxsackievirus B3 infects and disrupts human induced-pluripotent stem cell derived brain-like endothelial cells","volume":"13","author":"Mamana","year":"2023","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.jare.2024.11.022_b0370","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/bs.enz.2021.09.005","article-title":"RNA helicases required for viral propagation in humans","volume":"50","author":"Marecki","year":"2021","journal-title":"Enzymes"},{"issue":"6","key":"10.1016\/j.jare.2024.11.022_b0375","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.00495-23","article-title":"Interaction of teleost fish TRPV4 with DEAD box RNA helicase 1 regulates iridovirus replication","volume":"97","author":"Luo","year":"2023","journal-title":"J Virol"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0380","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1038\/s41467-018-04776-7","article-title":"The TRPV4 channel links calcium influx to DDX3X activity and viral infectivity","volume":"9","author":"Donate-Macian","year":"2018","journal-title":"Nat Commun"},{"issue":"14","key":"10.1016\/j.jare.2024.11.022_b0385","doi-asserted-by":"crossref","first-page":"3576","DOI":"10.1111\/bph.15267","article-title":"Structural determinants of TRPV4 inhibition and identification of new antagonists with antiviral activity","volume":"179","author":"Do\u00f1ate-Macian","year":"2022","journal-title":"Br J Pharmacol"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0390","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1146\/annurev-virology-100114-055226","article-title":"Innate and adaptive immune regulation during chronic viral infections","volume":"2","author":"Zuniga","year":"2015","journal-title":"Annu Rev Virol"},{"issue":"6","key":"10.1016\/j.jare.2024.11.022_b0395","doi-asserted-by":"crossref","first-page":"920","DOI":"10.3390\/v3060920","article-title":"Pattern recognition receptors and the innate immune response to viral infection","volume":"3","author":"Thompson","year":"2011","journal-title":"Viruses"},{"issue":"10","key":"10.1016\/j.jare.2024.11.022_b0400","doi-asserted-by":"crossref","first-page":"4922","DOI":"10.4049\/jimmunol.1500163","article-title":"Novel role of TRPML2 in the regulation of the innate immune response","volume":"195","author":"Sun","year":"2015","journal-title":"J Immunol"},{"issue":"2","key":"10.1016\/j.jare.2024.11.022_b0405","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s00424-015-1732-2","article-title":"The mucolipin-2 (TRPML2) ion channel: A tissue-specific protein crucial to normal cell function","volume":"468","author":"Cuajungco","year":"2016","journal-title":"Pflugers Arch"},{"issue":"2","key":"10.1016\/j.jare.2024.11.022_b0410","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.gene.2014.11.003","article-title":"PAX5 is the transcriptional activator of mucolipin-2 (MCOLN2) gene","volume":"555","author":"Valadez","year":"2015","journal-title":"Gene"},{"key":"10.1016\/j.jare.2024.11.022_b0415","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.ijbiomac.2021.10.014","article-title":"The crosstalk between pattern-recognition receptor signaling and calcium signaling","volume":"192","author":"Kong","year":"2021","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/j.jare.2024.11.022_b0420","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.bbrc.2021.04.065","article-title":"Inhibition of the transient receptor potential vanilloid 3 channel attenuates carbon tetrachloride-induced hepatic fibrosis","volume":"558","author":"Yan","year":"2021","journal-title":"Biochem Biophys Res Commun"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0425","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.jaci.2017.07.015","article-title":"Asthma predisposition and respiratory syncytial virus infection modulate transient receptor potential vanilloid 1 function in children's airways","volume":"141","author":"Harford","year":"2018","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"10.1016\/j.jare.2024.11.022_b0430","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02410-22","article-title":"C-fiber degeneration enhances alveolar macrophage-mediated IFN-\u03b1\/\u03b2 response to respiratory syncytial virus","volume":"10","author":"He","year":"2022","journal-title":"Microbiol Spectr"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0435","doi-asserted-by":"crossref","DOI":"10.1186\/s12974-016-0677-5","article-title":"Secreted herpes simplex virus-2 glycoprotein G alters thermal pain sensitivity by modifying NGF effects on TRPV1","volume":"13","author":"Cabrera","year":"2016","journal-title":"J Neuroinflamm"},{"key":"10.1016\/j.jare.2024.11.022_b0440","unstructured":"A Phase II, Double-Blind Trial of Recombinant Human Nerve Growth Factor for Treatment of HIV-Associated Sensory Neuropathy. (2021-11-04)[2024-08-14]. https:\/\/www.clinicaltrials.gov\/study\/NCT00000842."},{"key":"10.1016\/j.jare.2024.11.022_b0445","doi-asserted-by":"crossref","DOI":"10.1016\/j.mehy.2021.110685","article-title":"Transient Receptor Potential Vanilloid 1 (TRPV1) as a plausible novel therapeutic target for treating neurological complications in ZikaVirus","volume":"156","author":"Bhandari","year":"2021","journal-title":"Med Hypotheses"},{"issue":"23","key":"10.1016\/j.jare.2024.11.022_b0450","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/0024-3205(92)90045-Q","article-title":"Mechanism of action of capsaicin-like molecules on sensory neurons","volume":"51","author":"Dray","year":"1992","journal-title":"Life Sci"},{"issue":"9019","key":"10.1016\/j.jare.2024.11.022_b0455","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0140-6736(96)09058-7","article-title":"HIV as the cause of AIDS","volume":"348","author":"Barr\u00e9-Sinoussi","year":"1996","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.jare.2024.11.022_b0460","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1084\/jem.20122349","article-title":"Calcitonin gene-related peptide inhibits Langerhans cell-mediated HIV-1 transmission","volume":"210","author":"Ganor","year":"2013","journal-title":"J Exp Med"},{"issue":"5","key":"10.1016\/j.jare.2024.11.022_b0465","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1038\/mi.2010.32","article-title":"Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans-T cell conjugates","volume":"3","author":"Ganor","year":"2010","journal-title":"Mucosal Immunol"},{"issue":"22","key":"10.1016\/j.jare.2024.11.022_b0470","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2302509120","article-title":"TRPV1 activation in human Langerhans cells and T cells inhibits mucosal HIV-1 infection via CGRP-dependent and independent mechanisms","volume":"120","author":"Mariotton","year":"2023","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jare.2024.11.022_b0475","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbi.2014.10.008","article-title":"Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications","volume":"45","author":"Hong","year":"2015","journal-title":"Brain Behav Immun"},{"issue":"6","key":"10.1016\/j.jare.2024.11.022_b0480","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02939-20","article-title":"HIV-1 Vpr-induced proinflammatory response and apoptosis are mediated through the Sur1-Trpm4 channel in astrocytes","volume":"11","author":"Li","year":"2020","journal-title":"MBio"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0485","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1038\/s41467-017-01795-8","article-title":"HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration","volume":"8","author":"Chai","year":"2017","journal-title":"Nat Commun"},{"issue":"34","key":"10.1016\/j.jare.2024.11.022_b0490","doi-asserted-by":"crossref","first-page":"11485","DOI":"10.1523\/JNEUROSCI.0210-14.2014","article-title":"Activation of TRPML1 clears intraneuronal Abeta in preclinical models of HIV infection","volume":"34","author":"Bae","year":"2014","journal-title":"J Neurosci"},{"issue":"5","key":"10.1016\/j.jare.2024.11.022_b0495","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1038\/s41423-020-00630-3","article-title":"Necroptosis, pyroptosis and apoptosis: An intricate game of cell death","volume":"18","author":"Bertheloot","year":"2021","journal-title":"Cell Mol Immunol"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0500","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/s41392-023-01556-8","article-title":"SARS-CoV-2 spike protein receptor-binding domain perturbates intracellular calcium homeostasis and impairs pulmonary vascular endothelial cells","volume":"8","author":"Yang","year":"2023","journal-title":"Signal Transduct Target Ther"},{"issue":"23","key":"10.1016\/j.jare.2024.11.022_b0505","doi-asserted-by":"crossref","first-page":"4811","DOI":"10.1021\/bi00720a020","article-title":"Calcium uptake and membrane potential in mitochondria","volume":"13","author":"Rottenberg","year":"1974","journal-title":"Biochemistry"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0510","doi-asserted-by":"crossref","first-page":"11","DOI":"10.5483\/BMBRep.2008.41.1.011","article-title":"The role of mitochondria in apoptosis","volume":"41","author":"Jeong","year":"2008","journal-title":"BMB Rep"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0515","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1093\/cvr\/cvu112","article-title":"TNF-\u03b1-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes","volume":"103","author":"Roberge","year":"2014","journal-title":"Cardiovasc Res"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0520","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s00232-005-0839-3","article-title":"The role of TRP channels in oxidative stress-induced cell death","volume":"209","author":"Miller","year":"2006","journal-title":"J Membr Biol"},{"issue":"5381","key":"10.1016\/j.jare.2024.11.022_b0525","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1126\/science.281.5381.1309","article-title":"Mitochondria and apoptosis","volume":"281","author":"Green","year":"1998","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.jare.2024.11.022_b0530","doi-asserted-by":"crossref","first-page":"L1239","DOI":"10.1152\/ajplung.00161.2020","article-title":"Urgent reconsideration of lung edema as a preventable outcome in COVID-19: Inhibition of TRPV4 represents a promising and feasible approach","volume":"318","author":"Kuebler","year":"2020","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"5","key":"10.1016\/j.jare.2024.11.022_b0535","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1038\/emboj.2008.307","article-title":"TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum","volume":"28","author":"Wegierski","year":"2009","journal-title":"EMBO J"},{"issue":"3","key":"10.1016\/j.jare.2024.11.022_b0540","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1001025","article-title":"Local Ca2+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca2+ signals required for specific cell functions","volume":"9","author":"Cheng","year":"2011","journal-title":"PLoS Biol"},{"issue":"16","key":"10.1016\/j.jare.2024.11.022_b0545","doi-asserted-by":"crossref","first-page":"7470","DOI":"10.1128\/JVI.74.16.7470-7477.2000","article-title":"Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: novel mechanism for killing virus-infected cells","volume":"74","author":"Li","year":"2000","journal-title":"J Virol"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0550","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.chom.2013.12.003","article-title":"Cellular inhibitor of apoptosis protein cIAP2 protects against pulmonary tissue necrosis during influenza virus infection to promote host survival","volume":"15","author":"Rodrigue-Gervais","year":"2014","journal-title":"Cell Host Microbe"},{"issue":"2","key":"10.1016\/j.jare.2024.11.022_b0555","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.molcel.2014.01.027","article-title":"Staying alive: Cell death in antiviral immunity","volume":"54","author":"Upton","year":"2014","journal-title":"Mol Cell"},{"issue":"9","key":"10.1016\/j.jare.2024.11.022_b0560","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/s41419-018-0917-y","article-title":"SARS-coronavirus open reading frame-3a drives multimodal necrotic cell death","volume":"9","author":"Yue","year":"2018","journal-title":"Cell Death Dis"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0565","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/ncb2883","article-title":"Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis","volume":"16","author":"Cai","year":"2014","journal-title":"Nat Cell Biol"},{"issue":"8","key":"10.1016\/j.jare.2024.11.022_b0570","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.7150\/ijbs.59918","article-title":"The Impact of TRPV1 on cancer pathogenesis and therapy: A systematic review","volume":"17","author":"Li","year":"2021","journal-title":"Int J Biol Sci"},{"issue":"13","key":"10.1016\/j.jare.2024.11.022_b0575","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20133328","article-title":"The NLRP3 inflammasome: An overview of mechanisms of activation and regulation","volume":"20","author":"Kelley","year":"2019","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0580","doi-asserted-by":"crossref","first-page":"4664","DOI":"10.1038\/s41467-021-25015-6","article-title":"SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation","volume":"12","author":"Pan","year":"2021","journal-title":"Nat Commun"},{"issue":"7914","key":"10.1016\/j.jare.2024.11.022_b0585","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/s41586-022-04802-1","article-title":"Inflammasome activation in infected macrophages drives COVID-19 pathology","volume":"606","author":"Sefik","year":"2022","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.jare.2024.11.022_b0590","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/s41422-021-00519-4","article-title":"SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target","volume":"31","author":"Xia","year":"2021","journal-title":"Cell Res"},{"issue":"2","key":"10.1016\/j.jare.2024.11.022_b0595","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1159\/000488242","article-title":"Angiotensin II stimulates the NLRP3 inflammasome to induce podocyte injury and mitochondrial dysfunction","volume":"4","author":"Zhao","year":"2018","journal-title":"Kidney Dis (Basel)"},{"key":"10.1016\/j.jare.2024.11.022_b0600","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1038\/ncomms2608","article-title":"TRPM2 links oxidative stress to NLRP3 inflammasome activation","volume":"4","author":"Zhong","year":"2013","journal-title":"Nat Commun"},{"key":"10.1016\/j.jare.2024.11.022_b0605","doi-asserted-by":"crossref","first-page":"35016","DOI":"10.1038\/srep35016","article-title":"TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells","volume":"6","author":"Tseng","year":"2016","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0610","doi-asserted-by":"crossref","first-page":"3816","DOI":"10.1038\/s41467-024-48055-0","article-title":"Fatal COVID-19 pulmonary disease involves ferroptosis","volume":"15","author":"Qiu","year":"2024","journal-title":"Nat Commun"},{"key":"10.1016\/j.jare.2024.11.022_b0615","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102752","article-title":"SARS-CoV-2 ORF3a sensitizes cells to ferroptosis via Keap1-NRF2 axis","volume":"63","author":"Liu","year":"2023","journal-title":"Redox Biol"},{"key":"10.1016\/j.jare.2024.11.022_b0620","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102689","article-title":"HIV-1 Tat-mediated microglial ferroptosis involves the miR-204-ACSL4 signaling axis","volume":"62","author":"Kannan","year":"2023","journal-title":"Redox Biol"},{"issue":"19","key":"10.1016\/j.jare.2024.11.022_b0625","doi-asserted-by":"crossref","DOI":"10.3390\/ijms231911025","article-title":"Molecular mechanisms underlying Ca(2+)\/calmodulin-dependent protein kinase kinase signal transduction","volume":"23","author":"Tokumitsu","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"4","key":"10.1016\/j.jare.2024.11.022_b0630","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41580-020-00324-8","article-title":"Ferroptosis: Mechanisms, biology and role in disease","volume":"22","author":"Jiang","year":"2021","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"7","key":"10.1016\/j.jare.2024.11.022_b0635","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/j.cub.2023.02.060","article-title":"Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis","volume":"33","author":"Hirata","year":"2023","journal-title":"Curr Biol"},{"issue":"1","key":"10.1016\/j.jare.2024.11.022_b0640","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/s41392-022-01230-5","article-title":"CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis","volume":"7","author":"Wu","year":"2022","journal-title":"Signal Transduct Target Ther"},{"issue":"6","key":"10.1016\/j.jare.2024.11.022_b0645","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1002\/hep.22265","article-title":"The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells","volume":"47","author":"Mart\u00edn-V\u00edlchez","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.jare.2024.11.022_b0650","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.ceca.2019.05.007","article-title":"Focus on TRP channels in cystic fibrosis","volume":"81","author":"Grebert","year":"2019","journal-title":"Cell Calcium"},{"issue":"7","key":"10.1016\/j.jare.2024.11.022_b0655","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1038\/nm.2807","article-title":"Mechanisms of fibrosis: Therapeutic translation for fibrotic disease","volume":"18","author":"Wynn","year":"2012","journal-title":"Nat Med"},{"issue":"9","key":"10.1016\/j.jare.2024.11.022_b0660","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1038\/labinvest.2014.85","article-title":"TRPA1 is required for TGF-\u03b2 signaling and its loss blocks inflammatory fibrosis in mouse corneal stroma","volume":"94","author":"Okada","year":"2014","journal-title":"Lab Invest"},{"issue":"12","key":"10.1016\/j.jare.2024.11.022_b0665","doi-asserted-by":"crossref","first-page":"5225","DOI":"10.1172\/JCI75331","article-title":"TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice","volume":"124","author":"Rahaman","year":"2014","journal-title":"J Clin Invest"},{"issue":"2","key":"10.1016\/j.jare.2024.11.022_b0670","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jdermsci.2019.12.011","article-title":"Transient receptor potential vanilloid-3 (TRPV3) channel induces dermal fibrosis via the TRPV3\/TSLP\/Smad2\/3 pathways in dermal fibroblasts","volume":"97","author":"Um","year":"2020","journal-title":"J Dermatol Sci"},{"issue":"2","key":"10.1016\/j.jare.2024.11.022_b0675","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.taap.2014.08.006","article-title":"TGF-\u03b21-elevated TRPM7 channel regulates collagen expression in hepatic stellate cells via TGF-\u03b21\/Smad pathway","volume":"280","author":"Fang","year":"2014","journal-title":"Toxicol Appl Pharmacol"},{"issue":"3","key":"10.1016\/j.jare.2024.11.022_b0680","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10030483","article-title":"TRPM5 rs886277 polymorphism predicts hepatic fibrosis progression in non-cirrhotic HCV-infected patients","volume":"10","author":"Resino","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.jare.2024.11.022_b0685","doi-asserted-by":"crossref","unstructured":"zur Hausen H and de Villiers E M. Cancer \u201ccausation\u201d by infections--individual contributions and synergistic networks. Semin Oncol. 2014; 41(6): 860-875.","DOI":"10.1053\/j.seminoncol.2014.10.003"},{"key":"10.1016\/j.jare.2024.11.022_b0690","doi-asserted-by":"crossref","unstructured":"zur Hausen H. Viruses in human cancers. Science. 1991; 254(5035): 1167-1173.","DOI":"10.1126\/science.1659743"},{"key":"10.1016\/j.jare.2024.11.022_b0695","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/8114327","article-title":"Involvement of TRPC7-AS1 expression in hepatitis B virus-related hepatocellular carcinoma","volume":"2021","author":"Zhu","year":"2021","journal-title":"J Oncol"},{"key":"10.1016\/j.jare.2024.11.022_b0700","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.biopha.2015.02.024","article-title":"Silencing of TRPC1 regulates store-operated calcium entry and proliferation in Huh7 hepatocellular carcinoma cells","volume":"71","author":"Selli","year":"2015","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.jare.2024.11.022_b0705","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.biopha.2018.03.014","article-title":"Pharmacological inhibition of TRPV4 channel suppresses malignant biological behavior of hepatocellular carcinoma via modulation of ERK signaling pathway","volume":"101","author":"Fang","year":"2018","journal-title":"Biomed Pharmacother"}],"container-title":["Journal of Advanced Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123224005411?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123224005411?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T21:05:44Z","timestamp":1759784744000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2090123224005411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":141,"alternative-id":["S2090123224005411"],"URL":"https:\/\/doi.org\/10.1016\/j.jare.2024.11.022","relation":{},"ISSN":["2090-1232"],"issn-type":[{"value":"2090-1232","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transient receptor potential channels in viral infectious diseases: Biological characteristics and regulatory mechanisms","name":"articletitle","label":"Article Title"},{"value":"Journal of Advanced Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jare.2024.11.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V. on behalf of Cairo University.","name":"copyright","label":"Copyright"}]}}