{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T16:20:33Z","timestamp":1784737233338,"version":"3.55.0"},"reference-count":281,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T00:00:00Z","timestamp":1742774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012127","name":"Augusta University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012127","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01AG083947"],"award-info":[{"award-number":["R01AG083947"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01AG081874"],"award-info":[{"award-number":["R01AG081874"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["IGPP00059"],"award-info":[{"award-number":["IGPP00059"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01AG082207"],"award-info":[{"award-number":["R01AG082207"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["RF1NS135548"],"award-info":[{"award-number":["RF1NS135548"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Research"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.jare.2025.03.046","type":"journal-article","created":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T18:58:21Z","timestamp":1743706701000},"page":"343-362","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Comprehensive insights into emerging advances in the Neurobiology of anorexia"],"prefix":"10.1016","volume":"79","author":[{"given":"Liwei","family":"Mao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihai","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Kang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorelei","family":"Tucker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quanguang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"14","key":"10.1016\/j.jare.2025.03.046_b0005","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1056\/NEJMcp1803175","article-title":"Anorexia nervosa","volume":"382","author":"Mitchell","year":"2020","journal-title":"N Engl J Med"},{"issue":"7599","key":"10.1016\/j.jare.2025.03.046_b0010","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1136\/bmj.39171.616840.BE","article-title":"Anorexia nervosa","volume":"334","author":"Morris","year":"2007","journal-title":"BMJ"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0015","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.biopsych.2018.03.014","article-title":"Prevalence and correlates of DSM-5-defined eating disorders in a nationally representative sample of U.S. adults","volume":"84","author":"Udo","year":"2018","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.jare.2025.03.046_b0020","doi-asserted-by":"crossref","first-page":"15074","DOI":"10.1038\/nrdp.2015.74","article-title":"Anorexia nervosa","volume":"1","author":"Treasure","year":"2015","journal-title":"Nat Rev Dis Primers"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0025","first-page":"164","article-title":"The diagnosis and treatment of anorexia nervosa in childhood and adolescence","volume":"121","author":"Hebebrand","year":"2024","journal-title":"Dtsch Arztebl Int"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0030","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1097\/YCO.0000000000000739","article-title":"Incidence, prevalence and mortality of anorexia nervosa and bulimia nervosa","volume":"34","author":"van Eeden","year":"2021","journal-title":"Curr Opin Psychiatry"},{"issue":"9714","key":"10.1016\/j.jare.2025.03.046_b0035","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0140-6736(09)61748-7","article-title":"Eating disorders","volume":"375","author":"Treasure","year":"2010","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0040","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1192\/bjp.2019.113","article-title":"Anorexia nervosa: 30-year outcome","volume":"216","author":"Dobrescu","year":"2020","journal-title":"Br J Psychiatry"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0045","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1111\/j.1600-0447.2010.01641.x","article-title":"A comprehensive meta-analysis of the risk of suicide in eating disorders","volume":"124","author":"Preti","year":"2011","journal-title":"Acta Psychiatr Scand"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0050","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/wps.20128","article-title":"Risks of all-cause and suicide mortality in mental disorders: a meta-review","volume":"13","author":"Chesney","year":"2014","journal-title":"World Psychiatry"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0055","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1097\/YCO.0000000000000641","article-title":"Review of the burden of eating disorders: mortality, disability, costs, quality of life, and family burden","volume":"33","author":"van Hoeken","year":"2020","journal-title":"Curr Opin Psychiatry"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b0060","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/S2215-0366(15)00356-9","article-title":"Anorexia nervosa: aetiology, assessment, and treatment","volume":"2","author":"Zipfel","year":"2015","journal-title":"Lancet Psychiatry"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b0065","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.dld.2010.03.018","article-title":"Esophageal motility and symptoms in restricting and binge-eating\/purging anorexia","volume":"42","author":"Benini","year":"2010","journal-title":"Dig Liver Dis"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b0070","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.comppsych.2011.04.062","article-title":"Emotional eating in anorexia nervosa and bulimia nervosa","volume":"53","author":"Ricca","year":"2012","journal-title":"Compr Psychiatry"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0075","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.comppsych.2007.12.007","article-title":"Compulsive exercise to control shape or weight in eating disorders: prevalence, associated features, and treatment outcome","volume":"49","author":"Dalle Grave","year":"2008","journal-title":"Compr Psychiatry"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b0080","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1037\/h0025205","article-title":"Self-starvation of rats living in activity wheels on a restricted feeding schedule","volume":"64","author":"Routtenberg","year":"1967","journal-title":"J Comp Physiol Psychol"},{"issue":"3\u20134","key":"10.1016\/j.jare.2025.03.046_b0085","first-page":"203","article-title":"Excessive food aversion, compulsive exercise and decreased height gain due to fear of obesity in a prepubertal girl","volume":"62","author":"Ohzeki","year":"1994","journal-title":"Psychother Psychosom"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0090","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1002\/eat.10042","article-title":"Excessive exercise in anorexia nervosa and bulimia nervosa: relation to eating characteristics and general psychopathology","volume":"31","author":"Pe\u00f1as-Lled\u00f3","year":"2002","journal-title":"Int J Eat Disord"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b0095","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1002\/eat.22796","article-title":"Characterization and correlates of exercise among adolescents with anorexia nervosa and bulimia nervosa","volume":"50","author":"Nagata","year":"2017","journal-title":"Int J Eat Disord"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b0100","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1159\/000504583","article-title":"Efficacy of a specialized group intervention for compulsive exercise in inpatients with anorexia nervosa: a randomized controlled trial","volume":"89","author":"Dittmer","year":"2020","journal-title":"Psychother Psychosom"},{"key":"10.1016\/j.jare.2025.03.046_b0105","article-title":"Chronic food restriction in mice and increased systemic ghrelin induce preference for running wheel activity","volume":"155","author":"Tezenas du Montcel","year":"2023","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jare.2025.03.046_b0110","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.euroneuro.2023.02.014","article-title":"Engagement of the brain orexin system in activity-based anorexia behaviour in mice","volume":"70","author":"Sch\u00e9le","year":"2023","journal-title":"Eur Neuropsychopharmacol"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0115","doi-asserted-by":"crossref","first-page":"7233","DOI":"10.1038\/s41598-018-25548-9","article-title":"Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia","volume":"8","author":"Nobis","year":"2018","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0120","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1177\/070674377902400207","article-title":"Anorexia nervosa: death from complications of ruptured gastric ulcer","volume":"24","author":"Kline","year":"1979","journal-title":"Can J Psychiatry"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0125","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/eat.22548","article-title":"Solitary rectal ulcer syndrome in a patient with anorexia nervosa: a case report","volume":"49","author":"El Ghoch","year":"2016","journal-title":"Int J Eat Disord"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b0130","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1136\/gut.22.11.978","article-title":"Acute gastric dilatation with infarction and perforation. report of fatal outcome in patient with anorexia nervosa","volume":"22","author":"Saul","year":"1981","journal-title":"Gut"},{"issue":"10","key":"10.1016\/j.jare.2025.03.046_b0135","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1007\/BF01946155","article-title":"Running activity and gastric ulcers in the rat","volume":"28","author":"Barboriak","year":"1972","journal-title":"Experientia"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0140","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/0031-9384(91)90419-O","article-title":"Activity-based anorexia: relationship to gender and activity-stress ulcers","volume":"50","author":"Doerries","year":"1991","journal-title":"Physiol Behav"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0145","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0031-9384(93)90126-Z","article-title":"Stress ulcers in rats: the role of food intake, body weight, and time of day","volume":"54","author":"Yi","year":"1993","journal-title":"Physiol Behav"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0150","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0031-9384(97)00427-7","article-title":"The effects of food deprivation, nutritive and non-nutritive feeding and wheel running on gastric stress ulcers in rats","volume":"63","author":"Yi","year":"1998","journal-title":"Physiol Behav"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0155","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1016\/j.fertnstert.2005.10.048","article-title":"The psychobiology and diagnostic significance of amenorrhea in patients with anorexia nervosa","volume":"85","author":"Gendall","year":"2006","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0160","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/1098-108X(199407)16:1<53::AID-EAT2260160105>3.0.CO;2-V","article-title":"Amenorrhea in anorexia nervosa. Neuroendocrine control of hypothalamic dysfunction","volume":"16","author":"Golden","year":"1994","journal-title":"Int J Eat Disord"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0165","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1093\/jn\/123.7.1217","article-title":"Activity of the hypothalamic-pituitary-adrenal axis is elevated in rats with activity-based anorexia","volume":"123","author":"Burden","year":"1993","journal-title":"J Nutr"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0170","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.metabol.2011.11.016","article-title":"The effect of gonadal and adrenal steroid therapy on skeletal health in adolescents and young women with anorexia nervosa","volume":"61","author":"Divasta","year":"2012","journal-title":"Metabolism"},{"key":"10.1016\/j.jare.2025.03.046_b0175","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.bone.2018.02.021","article-title":"Magnetic resonance imaging and spectroscopy evidence of efficacy for adrenal and gonadal hormone replacement therapy in anorexia nervosa","volume":"110","author":"Vajapeyam","year":"2018","journal-title":"Bone"},{"key":"10.1016\/j.jare.2025.03.046_b0180","article-title":"Animal models for anorexia nervosa-a systematic review","volume":"14","author":"Scharner","year":"2020","journal-title":"Front Hum Neurosci"},{"key":"10.1016\/j.jare.2025.03.046_b0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.physbeh.2016.12.014","article-title":"Sex differences in response to activity-based anorexia model in C57Bl\/6 mice","volume":"170","author":"Achamrah","year":"2017","journal-title":"Physiol Behav"},{"issue":"13","key":"10.1016\/j.jare.2025.03.046_b0190","doi-asserted-by":"crossref","DOI":"10.3390\/cells12131710","article-title":"Establishment of a murine chronic anorexia nervosa model","volume":"12","author":"Staffeld","year":"2023","journal-title":"Cells"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b0195","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.biopsych.2020.06.030","article-title":"Vulnerable and resilient phenotypes in a mouse model of anorexia nervosa","volume":"90","author":"Beeler","year":"2021","journal-title":"Biol Psychiatry"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0200","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1093\/oxfordjournals.jhered.a109987","article-title":"Anorexia, a recessive mutation causing starvation in preweanling mice","volume":"75","author":"Maltais","year":"1984","journal-title":"J Hered"},{"key":"10.1016\/j.jare.2025.03.046_b0205","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3389\/fnins.2019.00059","article-title":"The anx\/anx mouse - a valuable resource in anorexia nervosa research","volume":"13","author":"Nilsson","year":"2019","journal-title":"Front Neurosci"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0210","doi-asserted-by":"crossref","first-page":"E418","DOI":"10.1152\/ajpendo.00081.2015","article-title":"Glucose intolerance and pancreatic \u03b2-cell dysfunction in the anorectic anx\/anx mouse","volume":"309","author":"Lindfors","year":"2015","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"52","key":"10.1016\/j.jare.2025.03.046_b0215","doi-asserted-by":"crossref","first-page":"14265","DOI":"10.1523\/JNEUROSCI.3308-07.2007","article-title":"Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity","volume":"27","author":"Unger","year":"2007","journal-title":"J Neurosci"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0220","doi-asserted-by":"crossref","DOI":"10.3390\/biom13050822","article-title":"Regulation of satiety by BDNF-e2-expressing neurons through TrkB activation in ventromedial hypothalamus","volume":"13","author":"Chu","year":"2023","journal-title":"Biomolecules"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0225","doi-asserted-by":"crossref","first-page":"444","DOI":"10.3109\/15622975.2011.562244","article-title":"A meta-analysis of circulating BDNF concentrations in anorexia nervosa","volume":"12","author":"Brandys","year":"2011","journal-title":"World J Biol Psychiatry"},{"issue":"9","key":"10.1016\/j.jare.2025.03.046_b0230","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1017\/S0033291724000394","article-title":"Longitudinal changes in brain-derived neurotrophic factor (BDNF) but not cytokines contribute to hippocampal recovery in anorexia nervosa above increases in body mass index","volume":"54","author":"Keeler","year":"2024","journal-title":"Psychol Med"},{"key":"10.1016\/j.jare.2025.03.046_b0235","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.pnpbp.2014.05.006","article-title":"Serum brain-derived neurotrophic factor and cognitive functioning in underweight, weight-recovered and partially weight-recovered females with anorexia nervosa","volume":"54","author":"Zwipp","year":"2014","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0240","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1139\/jpn.0942","article-title":"Serum brain-derived neurotrophic factor and peripheral indicators of the serotonin system in underweight and weight-recovered adolescent girls and women with anorexia nervosa","volume":"34","author":"Ehrlich","year":"2009","journal-title":"J Psychiatry Neurosci"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b0245","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1038\/sj.mp.4001281","article-title":"Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type","volume":"8","author":"Ribas\u00e9s","year":"2003","journal-title":"Mol Psychiatry"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0250","first-page":"153","article-title":"Brain derived neurotrophic factor gene Val66Met and -270C\/T polymorphisms and personality traits predisposing to anorexia nervosa","volume":"28","author":"Rybakowski","year":"2007","journal-title":"Neuro Endocrinol Lett"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b0255","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s00787-013-0495-6","article-title":"BDNF genetic variability modulates psychopathological symptoms in patients with eating disorders","volume":"23","author":"Gamero-Villarroel","year":"2014","journal-title":"Eur Child Adolesc Psychiatry"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b0260","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1111\/j.1601-183X.2007.00301.x","article-title":"Altered brain-derived neurotrophic factor blood levels and gene variability are associated with anorexia and bulimia","volume":"6","author":"Mercader","year":"2007","journal-title":"Genes Brain Behav"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0265","doi-asserted-by":"crossref","first-page":"e829","DOI":"10.1038\/tp.2016.98","article-title":"Higher reward value of starvation imagery in anorexia nervosa and association with the Val66Met BDNF polymorphism","volume":"6","author":"Clarke","year":"2016","journal-title":"Transl Psychiatry"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b0270","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1093\/hmg\/ddh137","article-title":"Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations","volume":"13","author":"Ribas\u00e9s","year":"2004","journal-title":"Hum Mol Genet"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0275","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1038\/sj.ejhg.5201351","article-title":"Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations","volume":"13","author":"Ribas\u00e9s","year":"2005","journal-title":"Eur J Hum Genet"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b0280","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/ajmg.b.32771","article-title":"5-HT2AR and BDNF gene variants in eating disorders susceptibility","volume":"183","author":"Ceccarini","year":"2020","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"issue":"9","key":"10.1016\/j.jare.2025.03.046_b0285","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1038\/sj.mp.4001670","article-title":"Contribution of NTRK2 to the genetic susceptibility to anorexia nervosa, harm avoidance and minimum body mass index","volume":"10","author":"Ribases","year":"2005","journal-title":"Mol Psychiatry"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0290","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/ajmg.b.32000","article-title":"No association of brain-derived neurotrophic factor Val66Met polymorphism with anorexia nervosa in Japanese","volume":"159b","author":"Ando","year":"2012","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0295","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.psyneuen.2006.11.003","article-title":"Family trios analysis of common polymorphisms in the obestatin\/ghrelin, BDNF and AGRP genes in patients with Anorexia nervosa: association with subtype, body-mass index, severity and age of onset","volume":"32","author":"Dardennes","year":"2007","journal-title":"Psychoneuroendocrinology"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0300","doi-asserted-by":"crossref","first-page":"441","DOI":"10.3109\/15622975.2011.605470","article-title":"The Val66Met polymorphism of the BDNF gene in anorexia nervosa: new data and a meta-analysis","volume":"14","author":"Brandys","year":"2013","journal-title":"World J Biol Psychiatry"},{"key":"10.1016\/j.jare.2025.03.046_b0305","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2022.1087075","article-title":"Long-lasting BDNF signaling alterations in the amygdala of adolescent female rats exposed to the activity-based anorexia model","volume":"16","author":"Mottarlini","year":"2022","journal-title":"Front Behav Neurosci"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b0310","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0166756","article-title":"Activity-based anorexia alters the expression of BDNF transcripts in the mesocorticolimbic reward circuit","volume":"11","author":"Ho","year":"2016","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0315","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1111\/j.1601-183X.2008.00394.x","article-title":"Dopaminergic and brain-derived neurotrophic factor signalling in inbred mice exposed to a restricted feeding schedule","volume":"7","author":"Gelegen","year":"2008","journal-title":"Genes Brain Behav"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0320","article-title":"The BDNF Val66Met polymorphism does not increase susceptibility to activity-based anorexia in rats","volume":"11","author":"Pietrucci","year":"2022","journal-title":"Biology (Basel)"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0325","doi-asserted-by":"crossref","first-page":"e776","DOI":"10.1038\/tp.2016.35","article-title":"BDNF-Val66Met variant and adolescent stress interact to promote susceptibility to anorexic behavior in mice","volume":"6","author":"Madra","year":"2016","journal-title":"Transl Psychiatry"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0330","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.beem.2017.10.011","article-title":"Human studies on hypothalamo-pituitary-adrenal (HPA) axis","volume":"31","author":"Liyanarachchi","year":"2017","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0335","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/s41398-020-00955-7","article-title":"Cortisol reactivity in patients with anorexia nervosa after stress induction","volume":"10","author":"Schmalbach","year":"2020","journal-title":"Transl Psychiatry"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0340","doi-asserted-by":"crossref","first-page":"E685","DOI":"10.1152\/ajpendo.00121.2011","article-title":"Decreased plasma ghrelin contributes to anorexia following novelty stress","volume":"301","author":"Saegusa","year":"2011","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jare.2025.03.046_b0345","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.70271","article-title":"Assessing the effects of stress on feeding behaviors in laboratory mice","volume":"11","author":"Francois","year":"2022","journal-title":"Elife"},{"issue":"20","key":"10.1016\/j.jare.2025.03.046_b0350","doi-asserted-by":"crossref","first-page":"4666","DOI":"10.1111\/bph.15219","article-title":"Vulnerability to psychological stress-induced anorexia in female mice depends on blockade of ghrelin signal in nucleus tractus solitarius","volume":"177","author":"Yamada","year":"2020","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.jare.2025.03.046_b0355","doi-asserted-by":"crossref","first-page":"587","DOI":"10.3389\/fphar.2019.00587","article-title":"Beyond the activity-based anorexia model: reinforcing values of exercise and feeding examined in stressed adolescent male and female mice","volume":"10","author":"Hurel","year":"2019","journal-title":"Front Pharmacol"},{"issue":"13","key":"10.1016\/j.jare.2025.03.046_b0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2024.03.027","article-title":"Repeated stress triggers seeking of a starvation-like state in anxiety-prone female mice","volume":"112","author":"Kucukdereli","year":"2024","journal-title":"Neuron"},{"key":"10.1016\/j.jare.2025.03.046_b0365","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molmet.2018.08.005","article-title":"Sex dependent impact of gestational stress on predisposition to eating disorders and metabolic disease","volume":"17","author":"Schroeder","year":"2018","journal-title":"Mol Metab"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0370","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1038\/s41467-018-03836-2","article-title":"Placental miR-340 mediates vulnerability to activity based anorexia in mice","volume":"9","author":"Schroeder","year":"2018","journal-title":"Nat Commun"},{"issue":"23","key":"10.1016\/j.jare.2025.03.046_b0375","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21238928","article-title":"Tumor necrosis factor \u03b1 and interleukin-1\u03b2 acutely inhibit AgRP neurons in the arcuate nucleus of the hypothalamus","volume":"21","author":"Chaves","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b0380","doi-asserted-by":"crossref","first-page":"5091","DOI":"10.1523\/JNEUROSCI.22-12-05091.2002","article-title":"Involvement of the arcuate nucleus of the hypothalamus in interleukin-1-induced anorexia","volume":"22","author":"Reyes","year":"2002","journal-title":"J Neurosci"},{"issue":"10","key":"10.1016\/j.jare.2025.03.046_b0385","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1139\/apnm-2018-0019","article-title":"The role of IL-6 in exercise-induced anorexia in normal-weight boys","volume":"43","author":"Hunschede","year":"2018","journal-title":"Appl Physiol Nutr Metab"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b0390","first-page":"697","article-title":"Health-related quality of life and inflammatory markers in malignant pleural mesothelioma","volume":"21","author":"Kao","year":"2013","journal-title":"Support Care Cancer"},{"issue":"9","key":"10.1016\/j.jare.2025.03.046_b0395","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0162971","article-title":"Gender difference in bacteria endotoxin-induced inflammatory and anorexic responses","volume":"11","author":"Kuo","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jare.2025.03.046_b0400","doi-asserted-by":"crossref","first-page":"29424","DOI":"10.1038\/srep29424","article-title":"Hypothalamic TLR2 triggers sickness behavior via a microglia-neuronal axis","volume":"6","author":"Jin","year":"2016","journal-title":"Sci Rep"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0405","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1210\/en.2015-2081","article-title":"Lipopolysacharide rapidly and completely suppresses AgRP neuron-mediated food intake in male mice","volume":"157","author":"Liu","year":"2016","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0410","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s11739-023-03374-w","article-title":"Gut microbiota, intestinal permeability, and systemic inflammation: a narrative review","volume":"19","author":"Di Vincenzo","year":"2024","journal-title":"Intern Emerg Med"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0415","doi-asserted-by":"crossref","first-page":"G559","DOI":"10.1152\/ajpgi.00066.2017","article-title":"Changes in intestinal microbiota composition and metabolism coincide with increased intestinal permeability in young adults under prolonged physiological stress","volume":"312","author":"Karl","year":"2017","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0420","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus","volume":"12","author":"Fearon","year":"2011","journal-title":"Lancet Oncol"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0425","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1002\/jcsm.12618","article-title":"Characterization of cachexia in the human fibrosarcoma HT-1080 mouse tumour model","volume":"11","author":"Bernardo","year":"2020","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0430","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.bbi.2010.01.006","article-title":"Deletion of the gene encoding MyD88 protects from anorexia in a mouse tumor model","volume":"24","author":"Ruud","year":"2010","journal-title":"Brain Behav Immun"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0435","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1002\/jcsm.12377","article-title":"MyD88 signalling is critical in the development of pancreatic cancer cachexia","volume":"10","author":"Zhu","year":"2019","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0440","doi-asserted-by":"crossref","first-page":"R403","DOI":"10.1152\/ajpregu.00395.2009","article-title":"MyD88 plays a key role in LPS-induced Stat3 activation in the hypothalamus","volume":"298","author":"Yamawaki","year":"2010","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0445","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1096\/fj.12-225433","article-title":"Inflammation- and tumor-induced anorexia and weight loss require MyD88 in hematopoietic\/myeloid cells but not in brain endothelial or neural cells","volume":"27","author":"Ruud","year":"2013","journal-title":"Faseb j"},{"key":"10.1016\/j.jare.2025.03.046_b0450","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2021.102147","article-title":"Endothelial peroxynitrite causes disturbance of neuronal oscillations by targeting caspase-1 in the arcuate nucleus","volume":"47","author":"Sun","year":"2021","journal-title":"Redox Biol"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0455","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1038\/bjc.2013.525","article-title":"Proteomic profiling of the hypothalamus in a mouse model of cancer-induced anorexia-cachexia","volume":"109","author":"Ihnatko","year":"2013","journal-title":"Br J Cancer"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0460","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.3892\/or.2016.4558","article-title":"MCG101-induced cancer anorexia-cachexia features altered expression of hypothalamic Nucb2 and Cartpt and increased plasma levels of cocaine- and amphetamine-regulated transcript peptides","volume":"35","author":"Burgos","year":"2016","journal-title":"Oncol Rep"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0465","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1002\/jcsm.12008","article-title":"Differences in food intake of tumour-bearing cachectic mice are associated with hypothalamic serotonin signalling","volume":"6","author":"Dwarkasing","year":"2015","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0470","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s13539-013-0121-y","article-title":"Hypothalamic food intake regulation in a cancer-cachectic mouse model","volume":"5","author":"Dwarkasing","year":"2014","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0475","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1038\/nn.4574","article-title":"Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus","volume":"20","author":"Campos","year":"2017","journal-title":"Nat Neurosci"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b0480","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.3390\/toxins7082845","article-title":"Murine anorectic response to deoxynivalenol (Vomitoxin) is sex-dependent","volume":"7","author":"Clark","year":"2015","journal-title":"Toxins (Basel)"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0485","doi-asserted-by":"crossref","first-page":"875","DOI":"10.2131\/jts.39.875","article-title":"Role of tumor necrosis factor-\u03b1 and interleukin-1\u03b2 in anorexia induction following oral exposure to the trichothecene deoxynivalenol (vomitoxin) in the mouse","volume":"39","author":"Wu","year":"2014","journal-title":"J Toxicol Sci"},{"key":"10.1016\/j.jare.2025.03.046_b0490","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.ecoenv.2018.06.005","article-title":"Anorectic responses to T-2 toxin, HT-2 toxin, diacetoxyscirpenol and neosolaniol correspond to plasma elevations of neurotransmitters 5-hydroxytryptamine and substance P","volume":"161","author":"Zhang","year":"2018","journal-title":"Ecotoxicol Environ Saf"},{"key":"10.1016\/j.jare.2025.03.046_b0495","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.taap.2017.09.020","article-title":"Gut satiety hormones cholecystokinin and glucagon-like Peptide-1(7-36) amide mediate anorexia induction by trichothecenes T-2 toxin, HT-2 toxin, diacetoxyscirpenol and neosolaniol","volume":"335","author":"Zhang","year":"2017","journal-title":"Toxicol Appl Pharmacol"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0500","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1093\/toxsci\/kft335","article-title":"Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol","volume":"138","author":"Wu","year":"2014","journal-title":"Toxicol Sci"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b0505","doi-asserted-by":"crossref","DOI":"10.3390\/toxins13080512","article-title":"Deoxynivalenol (Vomitoxin)-induced anorexia is induced by the release of intestinal hormones in mice","volume":"13","author":"Yue","year":"2021","journal-title":"Toxins (Basel)"},{"key":"10.1016\/j.jare.2025.03.046_b0510","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.tox.2018.04.007","article-title":"Anorectic response to the trichothecene T-2 toxin correspond to plasma elevations of the satiety hormone glucose-dependent insulinotropic polypeptide and peptide YY(3-36)","volume":"402\u2013403","author":"Sheng","year":"2018","journal-title":"Toxicology"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0515","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1093\/toxsci\/kfx128","article-title":"Role of peptide YY3-36 and glucose-dependent insulinotropic polypeptide in anorexia induction by trichothecences T-2 toxin, HT-2 toxin, diacetoxyscirpenol, and neosolaniol","volume":"159","author":"Zhang","year":"2017","journal-title":"Toxicol Sci"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0520","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s00204-016-1687-x","article-title":"Potential roles for calcium-sensing receptor (CaSR) and transient receptor potential ankyrin-1 (TRPA1) in murine anorectic response to deoxynivalenol (vomitoxin)","volume":"91","author":"Wu","year":"2017","journal-title":"Arch Toxicol"},{"issue":"10","key":"10.1016\/j.jare.2025.03.046_b0525","doi-asserted-by":"crossref","first-page":"4199","DOI":"10.3390\/toxins7104199","article-title":"High sensitivity of aged mice to deoxynivalenol (vomitoxin)-induced anorexia corresponds to elevated proinflammatory cytokine and satiety hormone responses","volume":"7","author":"Clark","year":"2015","journal-title":"Toxins (Basel)"},{"key":"10.1016\/j.jare.2025.03.046_b0530","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.116612","article-title":"The role of gut microbiota in anorexia induced by T-2 toxin","volume":"281","author":"Huang","year":"2024","journal-title":"Ecotoxicol Environ Saf"},{"issue":"10","key":"10.1016\/j.jare.2025.03.046_b0535","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0026134","article-title":"The food-contaminant deoxynivalenol modifies eating by targeting anorexigenic neurocircuitry","volume":"6","author":"Girardet","year":"2011","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0540","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2019.12.004","article-title":"GDF15 Induces Anorexia through Nausea and Emesis","volume":"31","author":"Borner","year":"2020","journal-title":"Cell Metab"},{"issue":"10","key":"10.1016\/j.jare.2025.03.046_b0545","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1038\/nm.4392","article-title":"GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates","volume":"23","author":"Mullican","year":"2017","journal-title":"Nat Med"},{"issue":"7675","key":"10.1016\/j.jare.2025.03.046_b0550","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/nature24042","article-title":"Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15","volume":"550","author":"Hsu","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.jare.2025.03.046_b0555","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.55164","article-title":"The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling","volume":"9","author":"Worth","year":"2020","journal-title":"Elife"},{"issue":"7928","key":"10.1016\/j.jare.2025.03.046_b0560","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1038\/s41586-022-05161-7","article-title":"Brainstem ADCYAP1(+) neurons control multiple aspects of sickness behaviour","volume":"609","author":"Ilanges","year":"2022","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0565","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1016\/j.celrep.2018.01.044","article-title":"Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15","volume":"22","author":"Jones","year":"2018","journal-title":"Cell Rep"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0570","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20231395","article-title":"Hepatic IRE1\u03b1-XBP1 signaling promotes GDF15-mediated anorexia and body weight loss in chemotherapy","volume":"221","author":"Tang","year":"2024","journal-title":"J Exp Med"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b0575","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201948804","article-title":"Muscle-derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress","volume":"21","author":"Ost","year":"2020","journal-title":"EMBO Rep"},{"key":"10.1016\/j.jare.2025.03.046_b0580","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.1037948","article-title":"GDF15 is an exercise-induced hepatokine regulated by glucagon and insulin in humans","volume":"13","author":"Plomgaard","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0585","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.cmet.2018.03.001","article-title":"Mechanisms of action and therapeutic application of glucagon-like peptide-1","volume":"27","author":"Drucker","year":"2018","journal-title":"Cell Metab"},{"issue":"40","key":"10.1016\/j.jare.2025.03.046_b0590","doi-asserted-by":"crossref","first-page":"16199","DOI":"10.1073\/pnas.1306799110","article-title":"Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6","volume":"110","author":"Shirazi","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0595","doi-asserted-by":"crossref","first-page":"E677","DOI":"10.1152\/ajpendo.00446.2012","article-title":"Central glucagon-like peptide 1 receptor-induced anorexia requires glucose metabolism-mediated suppression of AMPK and is impaired by central fructose","volume":"304","author":"Burmeister","year":"2013","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0600","doi-asserted-by":"crossref","first-page":"E651","DOI":"10.1152\/ajpendo.00113.2017","article-title":"The glucagon-like peptide-1 receptor in the ventromedial hypothalamus reduces short-term food intake in male mice by regulating nutrient sensor activity","volume":"313","author":"Burmeister","year":"2017","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.jare.2025.03.046_b0605","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.ecoenv.2018.02.003","article-title":"Potential roles for glucagon-like peptide-1(7-36) amide and cholecystokinin in anorectic response to the trichothecene mycotoxin T-2 toxin","volume":"153","author":"Wu","year":"2018","journal-title":"Ecotoxicol Environ Saf"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0610","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/toxsci\/kfx112","article-title":"Role of glucagon-like peptide-1 and gastric inhibitory peptide in anorexia induction following oral exposure to the trichothecene mycotoxin deoxynivalenol (Vomitoxin)","volume":"159","author":"Jia","year":"2017","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.jare.2025.03.046_b0615","doi-asserted-by":"crossref","first-page":"575","DOI":"10.2147\/DMSO.S387116","article-title":"The efficacy of GLP-1 analogues on appetite parameters, gastric emptying, food preference and taste among adults with obesity: systematic review of randomized controlled trials","volume":"16","author":"Aldawsari","year":"2023","journal-title":"Diabetes Metab Syndr Obes"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0620","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2023.01.001","article-title":"Activity-balanced GLP-1\/GDF15 dual agonist reduces body weight and metabolic disorder in mice and non-human primates","volume":"35","author":"Zhang","year":"2023","journal-title":"Cell Metab"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b0625","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1038\/s42255-023-00931-7","article-title":"Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice","volume":"5","author":"Liskiewicz","year":"2023","journal-title":"Nat Metab"},{"key":"10.1016\/j.jare.2025.03.046_b0630","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.foodchem.2018.01.107","article-title":"A casein hydrolysate increases GLP-1 secretion and reduces food intake","volume":"252","author":"O'Halloran","year":"2018","journal-title":"Food Chem"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0635","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.bbrc.2014.12.065","article-title":"Paraventricular NUCB2\/nesfatin-1 is directly targeted by leptin and mediates its anorexigenic effect","volume":"456","author":"Darambazar","year":"2015","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jare.2025.03.046_b0640","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1038\/ncomms2896","article-title":"Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway","volume":"4","author":"Gil","year":"2013","journal-title":"Nat Commun"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0645","doi-asserted-by":"crossref","first-page":"801","DOI":"10.15252\/embr.201338317","article-title":"Clusterin\/ApoJ enhances central leptin signaling through Lrp2-mediated endocytosis","volume":"15","author":"Byun","year":"2014","journal-title":"EMBO Rep"},{"key":"10.1016\/j.jare.2025.03.046_b0650","doi-asserted-by":"crossref","DOI":"10.1038\/s41586-024-08108-2","article-title":"Leptin-activated hypothalamic BNC2 neurons acutely suppress food intake","author":"Tan","year":"2024","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b0655","doi-asserted-by":"crossref","first-page":"3624","DOI":"10.1523\/JNEUROSCI.2742-12.2013","article-title":"Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively","volume":"33","author":"Zhan","year":"2013","journal-title":"J Neurosci"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0660","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1172\/JCI69395","article-title":"Leptin-promoted cilia assembly is critical for normal energy balance","volume":"124","author":"Han","year":"2014","journal-title":"J Clin Invest"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b0665","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1016\/j.ebiom.2015.09.044","article-title":"Mimecan, a hormone abundantly expressed in adipose tissue, reduced food intake independently of leptin signaling","volume":"2","author":"Cao","year":"2015","journal-title":"EBioMedicine"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0670","doi-asserted-by":"crossref","first-page":"3014","DOI":"10.1002\/jcsm.13093","article-title":"Lipopolysaccharide-induced hypothalamic inflammation in cancer cachexia-anorexia is amplified by tumour-derived prostaglandin E2","volume":"13","author":"Li","year":"2022","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.jare.2025.03.046_b0675","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.bbi.2016.06.014","article-title":"The involvement of prostaglandin E(2) in interleukin-1\u03b2 evoked anorexia is strain dependent","volume":"60","author":"Nilsson","year":"2017","journal-title":"Brain Behav Immun"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0680","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/s41556-020-00628-z","article-title":"Tumour-derived Dilp8\/INSL3 induces cancer anorexia by regulating feeding neuropeptides via Lgr3\/8 in the brain","volume":"23","author":"Yeom","year":"2021","journal-title":"Nat Cell Biol"},{"issue":"7645","key":"10.1016\/j.jare.2025.03.046_b0685","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/nature21697","article-title":"MC4R-dependent suppression of appetite by bone-derived lipocalin 2","volume":"543","author":"Mosialou","year":"2017","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0690","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1038\/s41467-021-22361-3","article-title":"Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia","volume":"12","author":"Olson","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.jare.2025.03.046_b0695","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.54095","article-title":"Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer","volume":"9","author":"Burfeind","year":"2020","journal-title":"Elife"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0700","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2019.07.010","article-title":"Acyl-CoA-binding protein is a lipogenic factor that triggers food intake and obesity","volume":"30","author":"Bravo-San Pedro","year":"2019","journal-title":"Cell Metab"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0705","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/s41419-019-2205-x","article-title":"Acyl-CoA-binding protein (ACBP): a phylogenetically conserved appetite stimulator","volume":"11","author":"Charmpilas","year":"2020","journal-title":"Cell Death Dis"},{"issue":"760","key":"10.1016\/j.jare.2025.03.046_b0710","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.adl0715","article-title":"Acyl-CoA binding protein for the experimental treatment of anorexia","volume":"16","author":"Chen","year":"2024","journal-title":"Sci Transl Med"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b0715","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1080\/15548627.2024.2402162","article-title":"The autophagy-repressive tissue hormone DBI\/ACBP (diazepam binding inhibitor, acyl-CoA binding protein) suppresses anorexia","volume":"20","author":"Chen","year":"2024","journal-title":"Autophagy"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b0720","doi-asserted-by":"crossref","first-page":"4706","DOI":"10.1172\/JCI71400","article-title":"Eating disorder predisposition is associated with ESRRA and HDAC4 mutations","volume":"123","author":"Cui","year":"2013","journal-title":"J Clin Invest"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b0725","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.celrep.2015.03.032","article-title":"Behavioral disturbances in estrogen-related receptor alpha-null mice","volume":"11","author":"Cui","year":"2015","journal-title":"Cell Rep"},{"key":"10.1016\/j.jare.2025.03.046_b0730","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.neuroscience.2016.04.054","article-title":"Loss of estrogen-related receptor alpha disrupts ventral-striatal synaptic function in female mice","volume":"329","author":"De Jes\u00fas-Cort\u00e9s","year":"2016","journal-title":"Neuroscience"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b0735","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1016\/j.metabol.2014.07.015","article-title":"GPR30 mediates anorectic estrogen-induced STAT3 signaling in the hypothalamus","volume":"63","author":"Kwon","year":"2014","journal-title":"Metabolism"},{"key":"10.1016\/j.jare.2025.03.046_b0740","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1146\/annurev.nutr.27.061406.093726","article-title":"Mechanisms of food intake repression in indispensable amino acid deficiency","volume":"27","author":"Gietzen","year":"2007","journal-title":"Annu Rev Nutr"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0745","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1007\/s00726-011-0836-z","article-title":"Somatostatin is involved in anorexia in mice fed a valine-deficient diet","volume":"42","author":"Nakahara","year":"2012","journal-title":"Amino Acids"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b0750","doi-asserted-by":"crossref","first-page":"E1446","DOI":"10.1152\/ajpendo.00427.2012","article-title":"Hypothalamic signaling in anorexia induced by indispensable amino acid deficiency","volume":"303","author":"Zhu","year":"2012","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b0755","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.celrep.2014.01.006","article-title":"Hypothalamic eIF2\u03b1 signaling regulates food intake","volume":"6","author":"Maurin","year":"2014","journal-title":"Cell Rep"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b0760","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1080\/15548627.2016.1215382","article-title":"Hypothalamic AMPK-induced autophagy increases food intake by regulating NPY and POMC expression","volume":"12","author":"Oh","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.jare.2025.03.046_b0765","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.neuroscience.2014.02.033","article-title":"Thiamine deficiency induces anorexia by inhibiting hypothalamic AMPK","volume":"267","author":"Liu","year":"2014","journal-title":"Neuroscience"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0770","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1002\/eat.23435","article-title":"Gut microbiota alteration in adolescent anorexia nervosa does not normalize with short-term weight restoration","volume":"54","author":"Schulz","year":"2021","journal-title":"Int J Eat Disord"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b0775","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.clnu.2013.11.006","article-title":"Alteration of intestinal barrier function during activity-based anorexia in mice","volume":"33","author":"J\u00e9sus","year":"2014","journal-title":"Clin Nutr"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0780","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/sj.mp.4001374","article-title":"Intestinal permeability is decreased in anorexia nervosa","volume":"9","author":"Monteleone","year":"2004","journal-title":"Mol Psychiatry"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b0785","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1016\/j.clnu.2022.06.036","article-title":"Intestinal permeability and appetite regulating peptides-reactive immunoglobulins in severely malnourished women with anorexia nervosa","volume":"41","author":"Grigioni","year":"2022","journal-title":"Clin Nutr"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0790","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.clnu.2020.05.002","article-title":"Gut microbiota alteration in a mouse model of Anorexia Nervosa","volume":"40","author":"Breton","year":"2021","journal-title":"Clin Nutr"},{"key":"10.1016\/j.jare.2025.03.046_b0795","article-title":"Proteome modifications of gut microbiota in mice with activity-based anorexia and starvation: role in ATP production","volume":"67\u201368","author":"Breton","year":"2019","journal-title":"Nutrition"},{"key":"10.1016\/j.jare.2025.03.046_b0800","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2024.106460","article-title":"Influence of the gut microbiome on appetite-regulating neuropeptides in the hypothalamus: Insight from conventional, antibiotic-treated, and germ-free mouse models of anorexia nervosa","volume":"193","author":"Roubalov\u00e1","year":"2024","journal-title":"Neurobiol Dis"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0805","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1016\/j.clnu.2021.04.014","article-title":"Gut microbiota depletion affects nutritional and behavioral responses to activity-based anorexia model in a sex-dependent manner","volume":"40","author":"Tirelle","year":"2021","journal-title":"Clin Nutr"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0810","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/s41564-023-01355-5","article-title":"The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice","volume":"8","author":"Fan","year":"2023","journal-title":"Nat Microbiol"},{"issue":"10","key":"10.1016\/j.jare.2025.03.046_b0815","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1210\/en.2019-00408","article-title":"The gut microbiome derived from anorexia nervosa patients impairs weight gain and behavioral performance in female mice","volume":"160","author":"Hata","year":"2019","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0820","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2021.1897216","article-title":"Gut microbial communities from patients with anorexia nervosa do not influence body weight in recipient germ-free mice","volume":"13","author":"Glenny","year":"2021","journal-title":"Gut Microbes"},{"issue":"10","key":"10.1016\/j.jare.2025.03.046_b0825","doi-asserted-by":"crossref","first-page":"e458","DOI":"10.1038\/tp.2014.98","article-title":"Bacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide \u03b1-MSH, at the origin of eating disorders","volume":"4","author":"Tennoune","year":"2014","journal-title":"Transl Psychiatry"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b0830","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1002\/eat.22531","article-title":"Elevated plasma concentrations of bacterial ClpB protein in patients with eating disorders","volume":"49","author":"Breton","year":"2016","journal-title":"Int J Eat Disord"},{"issue":"10","key":"10.1016\/j.jare.2025.03.046_b0835","doi-asserted-by":"crossref","DOI":"10.3390\/nu11102514","article-title":"Changes in microbiota and bacterial protein caseinolytic peptidase b during food restriction in mice: relevance for the onset and perpetuation of anorexia nervosa","volume":"11","author":"Dominique","year":"2019","journal-title":"Nutrients"},{"issue":"6590","key":"10.1016\/j.jare.2025.03.046_b0840","doi-asserted-by":"crossref","DOI":"10.1126\/science.abj3986","article-title":"Bacterial sensing via neuronal Nod2 regulates appetite and body temperature","volume":"376","author":"Gabanyi","year":"2022","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0845","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1002\/eat.23271","article-title":"Epigenetic regulation of the cannabinoid receptor CB1 in an activity-based rat model of anorexia nervosa","volume":"53","author":"D'Addario","year":"2020","journal-title":"Int J Eat Disord"},{"issue":"16","key":"10.1016\/j.jare.2025.03.046_b0850","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1111\/bph.13892","article-title":"Cannabinoid CB(1) \/CB(2) receptor agonists attenuate hyperactivity and body weight loss in a rat model of activity-based anorexia","volume":"174","author":"Scherma","year":"2017","journal-title":"Br J Pharmacol"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b0855","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.biopsych.2011.05.010","article-title":"Brain type 1 cannabinoid receptor availability in patients with anorexia and bulimia nervosa","volume":"70","author":"G\u00e9rard","year":"2011","journal-title":"Biol Psychiatry"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0860","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2016.118","article-title":"Association between cerebral cannabinoid 1 receptor availability and body mass index in patients with food intake disorders and healthy subjects: a [(18)F]MK-9470 PET study","volume":"6","author":"Ceccarini","year":"2016","journal-title":"Transl Psychiatry"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b0865","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s00259-013-2522-8","article-title":"Small animal PET imaging of the type 1 cannabinoid receptor in a rodent model for anorexia nervosa","volume":"41","author":"Casteels","year":"2014","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0870","doi-asserted-by":"crossref","first-page":"2814","DOI":"10.1038\/s41467-020-16348-9","article-title":"SIRT1 accelerates the progression of activity-based anorexia","volume":"11","author":"Robinette","year":"2020","journal-title":"Nat Commun"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b0875","doi-asserted-by":"crossref","DOI":"10.1111\/gbb.12765","article-title":"The role of SIRT1 in the basolateral amygdala in depression-like behaviors in mice","volume":"20","author":"Guo","year":"2021","journal-title":"Genes Brain Behav"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0880","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1038\/s42255-021-00398-4","article-title":"Central anorexigenic actions of bile acids are mediated by TGR5","volume":"3","author":"Perino","year":"2021","journal-title":"Nat Metab"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0885","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1016\/j.cell.2009.04.022","article-title":"Loss of GABAergic signaling by AgRP neurons to the parabrachial nucleus leads to starvation","volume":"137","author":"Wu","year":"2009","journal-title":"Cell"},{"issue":"590","key":"10.1016\/j.jare.2025.03.046_b0890","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abd6434","article-title":"The melanocortin-3 receptor is a pharmacological target for the regulation of anorexia","volume":"13","author":"Sweeney","year":"2021","journal-title":"Sci Transl Med"},{"issue":"36","key":"10.1016\/j.jare.2025.03.046_b0895","doi-asserted-by":"crossref","first-page":"14765","DOI":"10.1073\/pnas.1314137110","article-title":"NR2B subunit of the NMDA glutamate receptor regulates appetite in the parabrachial nucleus","volume":"110","author":"Wu","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7391","key":"10.1016\/j.jare.2025.03.046_b0900","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1038\/nature10899","article-title":"Deciphering a neuronal circuit that mediates appetite","volume":"483","author":"Wu","year":"2012","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b0905","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aav1640","article-title":"A lateral hypothalamus to basal forebrain neurocircuit promotes feeding by suppressing responses to anxiogenic environmental cues","volume":"5","author":"Cassidy","year":"2019","journal-title":"Sci Adv"},{"issue":"36","key":"10.1016\/j.jare.2025.03.046_b0910","doi-asserted-by":"crossref","first-page":"8678","DOI":"10.1523\/JNEUROSCI.0798-17.2017","article-title":"AgRP neurons can increase food intake during conditions of appetite suppression and inhibit anorexigenic parabrachial neurons","volume":"37","author":"Essner","year":"2017","journal-title":"J Neurosci"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0915","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.cmet.2016.04.006","article-title":"Parabrachial CGRP neurons control meal termination","volume":"23","author":"Campos","year":"2016","journal-title":"Cell Metab"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b0920","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1038\/s42255-020-00300-8","article-title":"AgRP neurons control compulsive exercise and survival in an activity-based anorexia model","volume":"2","author":"Miletta","year":"2020","journal-title":"Nat Metab"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0925","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1038\/s41380-022-01932-w","article-title":"AgRP neurons coordinate the mitigation of activity-based anorexia","volume":"28","author":"Sutton Hickey","year":"2023","journal-title":"Mol Psychiatry"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0930","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112789","article-title":"AgRP neurons are not indispensable for body weight maintenance in adult mice","volume":"42","author":"Cai","year":"2023","journal-title":"Cell Rep"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0935","doi-asserted-by":"crossref","first-page":"2200","DOI":"10.1038\/s41467-023-37912-z","article-title":"The melanocortin action is biased toward protection from weight loss in mice","volume":"14","author":"Li","year":"2023","journal-title":"Nat Commun"},{"issue":"8041","key":"10.1016\/j.jare.2025.03.046_b0940","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/s41586-024-08098-1","article-title":"A subcortical feeding circuit linking an interoceptive node to jaw movement","volume":"636","author":"Kosse","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.jare.2025.03.046_b0945","doi-asserted-by":"crossref","first-page":"10188","DOI":"10.1038\/ncomms10188","article-title":"An excitatory ventral hippocampus to lateral septum circuit that suppresses feeding","volume":"6","author":"Sweeney","year":"2015","journal-title":"Nat Commun"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0950","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.biopsych.2022.08.022","article-title":"Identification of a stress-sensitive anorexigenic neurocircuit from medial prefrontal cortex to lateral hypothalamus","volume":"93","author":"Clarke","year":"2023","journal-title":"Biol Psychiatry"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b0955","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2023.11.001","article-title":"An excitatory projection from the basal forebrain to the ventral tegmental area that underlies anorexia-like phenotypes","volume":"112","author":"Cai","year":"2024","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b0960","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s12868-016-0260-0","article-title":"Increased hypothalamic serotonin turnover in inflammation-induced anorexia","volume":"17","author":"Dwarkasing","year":"2016","journal-title":"BMC Neurosci"},{"key":"10.1016\/j.jare.2025.03.046_b0965","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.psyneuen.2015.02.006","article-title":"Serotonin 2C receptor contributes to gender differences in stress-induced hypophagia in aged mice","volume":"55","author":"Yamada","year":"2015","journal-title":"Psychoneuroendocrinology"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b0970","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s00360-016-0961-9","article-title":"Food intake inhibition in rainbow trout induced by activation of serotonin 5-HT2C receptors is associated with increases in POMC, CART and CRF mRNA abundance in hypothalamus","volume":"186","author":"P\u00e9rez-Maceira","year":"2016","journal-title":"J Comp Physiol B"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b0975","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109997","article-title":"G\u03b1(i\/o)-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents","volume":"37","author":"Yoo","year":"2021","journal-title":"Cell Rep"},{"issue":"44","key":"10.1016\/j.jare.2025.03.046_b0980","doi-asserted-by":"crossref","first-page":"14630","DOI":"10.1523\/JNEUROSCI.5412-09.2010","article-title":"A serotonin and melanocortin circuit mediates D-fenfluramine anorexia","volume":"30","author":"Xu","year":"2010","journal-title":"J Neurosci"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b0985","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.npep.2014.07.003","article-title":"The effects of serotonin1A receptor on female mice body weight and food intake are associated with the differential expression of hypothalamic neuropeptides and the GABAA receptor","volume":"48","author":"Butt","year":"2014","journal-title":"Neuropeptides"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b0990","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.celrep.2017.10.003","article-title":"Adaptive control of dorsal raphe by 5-HT4 in the prefrontal cortex prevents persistent hypophagia following stress","volume":"21","author":"Jean","year":"2017","journal-title":"Cell Rep"},{"issue":"30","key":"10.1016\/j.jare.2025.03.046_b0995","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.2192-23.2024","article-title":"A light-responsive neural circuit suppresses feeding","volume":"44","author":"Liu","year":"2024","journal-title":"J Neurosci"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b1000","doi-asserted-by":"crossref","first-page":"e203","DOI":"10.1038\/tp.2012.131","article-title":"The nucleus accumbens 5-HTR4-CART pathway ties anorexia to hyperactivity","volume":"2","author":"Jean","year":"2012","journal-title":"Transl Psychiatry"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b1005","doi-asserted-by":"crossref","first-page":"3765","DOI":"10.1038\/s41380-019-0633-8","article-title":"Dopamine D2 receptor overexpression in the nucleus accumbens core induces robust weight loss during scheduled fasting selectively in female mice","volume":"26","author":"Welch","year":"2021","journal-title":"Mol Psychiatry"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b1010","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1038\/s41467-024-46874-9","article-title":"Nucleus accumbens D1- and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure","volume":"15","author":"Walle","year":"2024","journal-title":"Nat Commun"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b1015","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1016\/j.euroneuro.2016.09.003","article-title":"Chemogenetic activation of dopamine neurons in the ventral tegmental area, but not substantia nigra, induces hyperactivity in rats","volume":"26","author":"Boekhoudt","year":"2016","journal-title":"Eur Neuropsychopharmacol"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b1020","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.1038\/npp.2017.63","article-title":"The role of mesolimbic reward neurocircuitry in prevention and rescue of the activity-based anorexia (ABA) phenotype in rats","volume":"42","author":"Foldi","year":"2017","journal-title":"Neuropsychopharmacology"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b1025","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1038\/s41593-022-01062-0","article-title":"A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice","volume":"25","author":"Cai","year":"2022","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.jare.2025.03.046_b1030","doi-asserted-by":"crossref","first-page":"11905","DOI":"10.1038\/ncomms11905","article-title":"Genetically and functionally defined NTS to PBN brain circuits mediating anorexia","volume":"7","author":"Roman","year":"2016","journal-title":"Nat Commun"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b1035","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2019.12.012","article-title":"Calcitonin receptor neurons in the mouse nucleus tractus solitarius control energy balance via the non-aversive suppression of feeding","volume":"31","author":"Cheng","year":"2020","journal-title":"Cell Metab"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b1040","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s13578-022-00914-3","article-title":"Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake","volume":"12","author":"Singh","year":"2022","journal-title":"Cell Biosci"},{"issue":"9","key":"10.1016\/j.jare.2025.03.046_b1045","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1038\/nn.3767","article-title":"Central amygdala PKC-\u03b4(+) neurons mediate the influence of multiple anorexigenic signals","volume":"17","author":"Cai","year":"2014","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.jare.2025.03.046_b1050","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2022.101443","article-title":"Dissecting a disynaptic central amygdala-parasubthalamic nucleus neural circuit that mediates cholecystokinin-induced eating suppression","volume":"58","author":"Sanchez","year":"2022","journal-title":"Mol Metab"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b1055","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1038\/s41467-019-10715-x","article-title":"A bed nucleus of stria terminalis microcircuit regulating inflammation-associated modulation of feeding","volume":"10","author":"Wang","year":"2019","journal-title":"Nat Commun"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b1060","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2024.113933","article-title":"Development of activity-based anorexia requires PKC-\u03b4 neurons in two central extended amygdala nuclei","volume":"43","author":"Schnapp","year":"2024","journal-title":"Cell Rep"},{"issue":"7871","key":"10.1016\/j.jare.2025.03.046_b1065","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/s41586-021-03769-9","article-title":"Structural basis of ketamine action on human NMDA receptors","volume":"596","author":"Zhang","year":"2021","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b1070","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/eat.22937","article-title":"Single injection of ketamine during mid-adolescence promotes long-lasting resilience to activity-based anorexia of female mice by increasing food intake and attenuating hyperactivity as well as anxiety-like behavior","volume":"51","author":"Chen","year":"2018","journal-title":"Int J Eat Disord"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b1075","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s00429-023-02740-w","article-title":"Ketamine ameliorates activity-based anorexia of adolescent female mice through changes in GluN2B-containing NMDA receptors at postsynaptic cytoplasmic locations of pyramidal neurons and interneurons of medial prefrontal cortex","volume":"229","author":"Li","year":"2024","journal-title":"Brain Struct Funct"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b1080","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1002\/eat.24036","article-title":"Three daily intraperitoneal injections of sub-anesthetic ketamine ameliorate activity-based anorexia vulnerability of adult female mice","volume":"57","author":"Goodwin-Groen","year":"2024","journal-title":"Int J Eat Disord"},{"key":"10.1016\/j.jare.2025.03.046_b1085","doi-asserted-by":"crossref","first-page":"763","DOI":"10.3389\/fpsyt.2020.00763","article-title":"Remission from chronic anorexia nervosa with ketogenic diet and ketamine: case report","volume":"11","author":"Scolnick","year":"2020","journal-title":"Front Psychiatry"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b1090","doi-asserted-by":"crossref","first-page":"3751","DOI":"10.1007\/s40519-022-01455-x","article-title":"Ketogenic diet and ketamine infusiontreatment to target chronic persistent eating disorder psychopathologyin anorexia nervosa: a pilot study","volume":"27","author":"Calabrese","year":"2022","journal-title":"Eat Weight Disord"},{"key":"10.1016\/j.jare.2025.03.046_b1095","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.neulet.2018.04.019","article-title":"Effects of a histamine H(4) receptor antagonist on cisplatin-induced anorexia in mice","volume":"676","author":"Yamamoto","year":"2018","journal-title":"Neurosci Lett"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b1100","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1007\/s00535-012-0746-1","article-title":"Aprepitant plus granisetron and dexamethasone for prevention of chemotherapy-induced nausea and vomiting in patients with gastric cancer treated with S-1 plus cisplatin","volume":"48","author":"Oyama","year":"2013","journal-title":"J Gastroenterol"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b1105","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1007\/s00210-019-01646-x","article-title":"Activation of orexinergic and histaminergic pathway involved in therapeutic effect of histamine H(4) receptor antagonist against cisplatin-induced anorexia in mice","volume":"392","author":"Yamamoto","year":"2019","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b1110","doi-asserted-by":"crossref","first-page":"e613","DOI":"10.1038\/tp.2015.109","article-title":"Dopamine D2\/3 receptor antagonism reduces activity-based anorexia","volume":"5","author":"Klenotich","year":"2015","journal-title":"Transl Psychiatry"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b1115","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S0278-5846(01)00174-9","article-title":"A single blind comparison of amisulpride, fluoxetine and clomipramine in the treatment of restricting anorectics","volume":"25","author":"Ruggiero","year":"2001","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"7","key":"10.1016\/j.jare.2025.03.046_b1120","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1038\/npp.2012.7","article-title":"Olanzapine, but not fluoxetine, treatment increases survival in activity-based anorexia in mice","volume":"37","author":"Klenotich","year":"2012","journal-title":"Neuropsychopharmacology"},{"issue":"14","key":"10.1016\/j.jare.2025.03.046_b1125","doi-asserted-by":"crossref","first-page":"2617","DOI":"10.1200\/JCO.22.01997","article-title":"Randomized double-blind placebo-controlled study of olanzapine for chemotherapy-related anorexia in patients with locally advanced or metastatic gastric, hepatopancreaticobiliary, and lung cancer","volume":"41","author":"Sandhya","year":"2023","journal-title":"J Clin Oncol"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b1130","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1176\/appi.ajp.2018.18101125","article-title":"Olanzapine versus placebo in adult outpatients with anorexia nervosa: a randomized clinical trial","volume":"176","author":"Attia","year":"2019","journal-title":"Am J Psychiatry"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b1135","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s13539-012-0084-4","article-title":"Protective effects of an anti-melanocortin-4 receptor scFv derivative in lipopolysaccharide-induced cachexia in rats","volume":"4","author":"Peter","year":"2013","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b1140","doi-asserted-by":"crossref","DOI":"10.3390\/nu13020709","article-title":"A systematic review and meta-analysis finds increased blood levels of all forms of ghrelin in both restricting and binge-eating\/purging subtypes of anorexia nervosa","volume":"13","author":"Seidel","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.jare.2025.03.046_b1145","doi-asserted-by":"crossref","DOI":"10.1016\/j.appet.2024.107259","article-title":"Anorexia of ageing is associated with elevated fasted and lower post-prandial ghrelin, independent of ghrelin O-acyltransferase","volume":"196","author":"Holliday","year":"2024","journal-title":"Appetite"},{"issue":"16","key":"10.1016\/j.jare.2025.03.046_b1150","doi-asserted-by":"crossref","first-page":"2814","DOI":"10.1017\/S0033291720001440","article-title":"Dissociable hormonal profiles for psychopathology and stress in anorexia and bulimia nervosa","volume":"51","author":"Westwater","year":"2021","journal-title":"Psychol Med"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b1155","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1503\/jpn.190031","article-title":"Metabolic state and value-based decision-making in acute and recovered female patients with anorexia nervosa","volume":"45","author":"Bernardoni","year":"2020","journal-title":"J Psychiatry Neurosci"},{"issue":"9","key":"10.1016\/j.jare.2025.03.046_b1160","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9092782","article-title":"Unexpected association of desacyl-ghrelin with physical activity and chronic food restriction: a translational study on anorexia nervosa","volume":"9","author":"Duriez","year":"2020","journal-title":"J Clin Med"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b1165","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1055\/s-0030-1252017","article-title":"Changes in acyl ghrelin, des-acyl ghrelin, and ratio of acyl ghrelin to total ghrelin with short-term refeeding in female inpatients with restricting-type anorexia nervosa","volume":"42","author":"Koyama","year":"2010","journal-title":"Horm Metab Res"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b1170","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.euroneuro.2016.03.010","article-title":"Ghrelin treatment prevents development of activity based anorexia in mice","volume":"26","author":"Legrand","year":"2016","journal-title":"Eur Neuropsychopharmacol"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b1175","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1124\/jpet.118.249086","article-title":"In vitro and in vivo characterization of novel stable peptidic ghrelin analogs: beneficial effects in the settings of lipopolysaccharide-induced anorexia in mice","volume":"366","author":"Holubov\u00e1","year":"2018","journal-title":"J Pharmacol Exp Ther"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b1180","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202201482R","article-title":"Soy-fortelin: A ghrelin sensitivity-enhancing peptide that stimulates food intake in aged mice","volume":"37","author":"Shimizu","year":"2023","journal-title":"Faseb j"},{"issue":"10","key":"10.1016\/j.jare.2025.03.046_b1185","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1002\/mnfr.201400100","article-title":"Orally administered \u03b4 opioid agonist peptide rubiscolin-6 stimulates food intake in aged mice with ghrelin resistance","volume":"58","author":"Miyazaki","year":"2014","journal-title":"Mol Nutr Food Res"},{"key":"10.1016\/j.jare.2025.03.046_b1190","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.ejphar.2017.10.047","article-title":"Z-505 hydrochloride ameliorates chemotherapy-induced anorexia in rodents via activation of the ghrelin receptor, GHSR1a","volume":"818","author":"Shiomi","year":"2018","journal-title":"Eur J Pharmacol"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b1195","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18050986","article-title":"Oral treatment with the ghrelin receptor agonist HM01 attenuates cachexia in mice bearing colon-26 (C26) tumors","volume":"18","author":"Villars","year":"2017","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b1200","doi-asserted-by":"crossref","first-page":"4633","DOI":"10.1038\/s41467-022-32135-0","article-title":"Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer","volume":"13","author":"Queiroz","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.jare.2025.03.046_b1205","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2021.101327","article-title":"LEAP2 deletion in mice enhances ghrelin's actions as an orexigen and growth hormone secretagogue","volume":"53","author":"Shankar","year":"2021","journal-title":"Mol Metab"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b1210","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqae132","article-title":"The LEAP2 response to cancer-related anorexia-cachexia syndrome in male mice and patients","volume":"165","author":"Varshney","year":"2024","journal-title":"Endocrinology"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b1215","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1093\/annonc\/mdx192","article-title":"ROMANA 3: a phase 3 safety extension study of anamorelin in advanced non-small-cell lung cancer (NSCLC) patients with cachexia","volume":"28","author":"Currow","year":"2017","journal-title":"Ann Oncol"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b1220","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S1470-2045(15)00558-6","article-title":"Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials","volume":"17","author":"Temel","year":"2016","journal-title":"Lancet Oncol"},{"issue":"1","key":"10.1016\/j.jare.2025.03.046_b1225","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.17m11585","article-title":"Treatment with a ghrelin agonist in outpatient women with anorexia nervosa: a randomized clinical trial","volume":"79","author":"Fazeli","year":"2018","journal-title":"J Clin Psychiatry"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b1230","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2020.10.023","article-title":"GDF-15 neutralization alleviates platinum-based chemotherapy-induced emesis, anorexia, and weight loss in mice and nonhuman primates","volume":"32","author":"Breen","year":"2020","journal-title":"Cell Metab"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b1235","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1038\/s41591-020-0945-x","article-title":"Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice","volume":"26","author":"Suriben","year":"2020","journal-title":"Nat Med"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b1240","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1002\/jcsm.13219","article-title":"GDNF family receptor alpha-like antagonist antibody alleviates chemotherapy-induced cachexia in melanoma-bearing mice","volume":"14","author":"Lee","year":"2023","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b1245","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1158\/1078-0432.CCR-23-1631","article-title":"A phase Ib first-in-patient study assessing the safety, tolerability, pharmacokinetics, and pharmacodynamics of ponsegromab in participants with cancer and cachexia","volume":"30","author":"Crawford","year":"2024","journal-title":"Clin Cancer Res"},{"issue":"19","key":"10.1016\/j.jare.2025.03.046_b1250","doi-asserted-by":"crossref","DOI":"10.1172\/JCI162365","article-title":"TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons","volume":"132","author":"Xie","year":"2022","journal-title":"J Clin Invest"},{"issue":"16","key":"10.1016\/j.jare.2025.03.046_b1255","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2300015120","article-title":"A small-molecule degrader of TET3 as treatment for anorexia nervosa in an animal model","volume":"120","author":"Lv","year":"2023","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jare.2025.03.046_b1260","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.bbrc.2022.08.011","article-title":"Atractylodin alleviates cancer anorexia-cachexia syndrome by regulating NPY through hypothalamic Sirt1\/AMPK axis-induced autophagy","volume":"625","author":"Yu","year":"2022","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jare.2025.03.046_b1265","doi-asserted-by":"crossref","DOI":"10.1016\/j.npep.2021.102180","article-title":"Onion component, isoalliin, stimulates feeding and activates the arcuate nucleus neuropeptide Y, ghrelin- and Ninjin'yoeito-responsive neurons","volume":"89","author":"Wang","year":"2021","journal-title":"Neuropeptides"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b1270","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1002\/ptr.5585","article-title":"Effect of embelin against lipopolysaccharide-induced sickness behaviour in mice","volume":"30","author":"Shaikh","year":"2016","journal-title":"Phytother Res"},{"key":"10.1016\/j.jare.2025.03.046_b1275","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/j.biopha.2018.10.004","article-title":"Bioactive phenolic fraction of Citrus maxima abate lipopolysaccharide-induced sickness behaviour and anorexia in mice: in-silico molecular docking and dynamic studies of biomarkers against NF-\u03baB","volume":"108","author":"Nandeesh","year":"2018","journal-title":"Biomed Pharmacother"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b1280","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1002\/ptr.3495","article-title":"Saffron (Crocus sativus) aqueous extract and its constituent crocin reduces stress-induced anorexia in mice","volume":"25","author":"Halataei","year":"2011","journal-title":"Phytother Res"},{"issue":"2","key":"10.1016\/j.jare.2025.03.046_b1285","first-page":"2665","article-title":"Novel herbal medicine LA16001 ameliorates cisplatin-induced anorexia","volume":"17","author":"Woo","year":"2018","journal-title":"Mol Med Rep"},{"issue":"9","key":"10.1016\/j.jare.2025.03.046_b1290","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0139325","article-title":"Patterns of brain activation and meal reduction induced by abdominal surgery in mice and modulation by rikkunshito","volume":"10","author":"Wang","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jare.2025.03.046_b1295","doi-asserted-by":"crossref","first-page":"27516","DOI":"10.1038\/srep27516","article-title":"CRF receptor 1 antagonism and brain distribution of active components contribute to the ameliorative effect of rikkunshito on stress-induced anorexia","volume":"6","author":"Mogami","year":"2016","journal-title":"Sci Rep"},{"issue":"11","key":"10.1016\/j.jare.2025.03.046_b1300","doi-asserted-by":"crossref","DOI":"10.1111\/nmo.14900","article-title":"Rikkunshito improves anorexia through ghrelin- and orexin-dependent activation of the brain hypothalamus and mesolimbic dopaminergic pathway in rats","volume":"36","author":"Yakabi","year":"2024","journal-title":"Neurogastroenterol Motil"},{"issue":"4","key":"10.1016\/j.jare.2025.03.046_b1305","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.3892\/mmr.2016.4889","article-title":"Sip-jeon-dea-bo-tang, a traditional herbal medicine, ameliorates cisplatin-induced anorexia via the activation of JAK1\/STAT3-mediated leptin and IL-6 production in the fat tissue of mice","volume":"13","author":"Woo","year":"2016","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.jare.2025.03.046_b1310","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/736563","article-title":"Effect of Sipjeondaebo-tang on cancer-induced anorexia and cachexia in CT-26 tumor-bearing mice","volume":"2014","author":"Choi","year":"2014","journal-title":"Mediators Inflamm"},{"key":"10.1016\/j.jare.2025.03.046_b1315","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.npep.2019.03.001","article-title":"Ninjin-yoeito activates ghrelin-responsive and unresponsive NPY neurons in the arcuate nucleus and counteracts cisplatin-induced anorexia","volume":"75","author":"Goswami","year":"2019","journal-title":"Neuropeptides"},{"key":"10.1016\/j.jare.2025.03.046_b1320","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3389\/fnut.2020.00104","article-title":"Ninjin'yoeito targets distinct Ca(2+) channels to activate ghrelin-responsive vs. unresponsive NPY neurons in the arcuate nucleus","volume":"7","author":"Goswami","year":"2020","journal-title":"Front Nutr"},{"key":"10.1016\/j.jare.2025.03.046_b1325","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.bbi.2014.01.005","article-title":"Calorie restriction dose-dependently abates lipopolysaccharide-induced fever, sickness behavior, and circulating interleukin-6 while increasing corticosterone","volume":"40","author":"MacDonald","year":"2014","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.jare.2025.03.046_b1330","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.bbi.2021.04.018","article-title":"Type I interferon mediated induction of somatostatin leads to suppression of ghrelin and appetite thereby promoting viral immunity in mice","volume":"95","author":"Stutte","year":"2021","journal-title":"Brain Behav Immun"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b1335","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112814","article-title":"CD4+ Tcells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection","volume":"42","author":"Redford","year":"2023","journal-title":"Cell Rep"},{"issue":"40","key":"10.1016\/j.jare.2025.03.046_b1340","doi-asserted-by":"crossref","first-page":"24998","DOI":"10.1073\/pnas.2003656117","article-title":"CD8 T cells drive anorexia, dysbiosis, and blooms of a commensal with immunosuppressive potential after viral infection","volume":"117","author":"Labarta-Bajo","year":"2020","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b1345","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2016.07.026","article-title":"Opposing effects of fasting metabolism on tissue tolerance in bacterial and viral inflammation","volume":"166","author":"Wang","year":"2016","journal-title":"Cell"},{"issue":"10","key":"10.1016\/j.jare.2025.03.046_b1350","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20202151","article-title":"Hepatic FGF21 preserves thermoregulation and cardiovascular function during bacterial inflammation","volume":"218","author":"Huen","year":"2021","journal-title":"J Exp Med"},{"issue":"3","key":"10.1016\/j.jare.2025.03.046_b1355","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2017.01.006","article-title":"Pathogen-mediated inhibition of anorexia promotes host survival and transmission","volume":"168","author":"Rao","year":"2017","journal-title":"Cell"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b1360","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1038\/s41366-019-0365-5","article-title":"GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP\/NTS","volume":"43","author":"Tsai","year":"2019","journal-title":"Int J Obes (Lond)"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b1365","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.cmet.2016.04.013","article-title":"Adult NG2-glia are required for median eminence-mediated leptin sensing and body weight control","volume":"23","author":"Djogo","year":"2016","journal-title":"Cell Metab"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b1370","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.2337\/db18-1009","article-title":"Long-acting neurotensin synergizes with liraglutide to reverse obesity through a melanocortin-dependent pathway","volume":"68","author":"Ratner","year":"2019","journal-title":"Diabetes"},{"issue":"9","key":"10.1016\/j.jare.2025.03.046_b1375","doi-asserted-by":"crossref","first-page":"4638","DOI":"10.1021\/acs.jmedchem.9b00241","article-title":"Novel tetrahydroquinazolinamines as selective histamine 3 receptor antagonists for the treatment of obesity","volume":"62","author":"Kumar","year":"2019","journal-title":"J Med Chem"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b1380","doi-asserted-by":"crossref","DOI":"10.15252\/emmm.202318024","article-title":"HMBA ameliorates obesity by MYH9- and ACTG1-dependent regulation of hypothalamic neuropeptides","volume":"15","author":"Park","year":"2023","journal-title":"EMBO Mol Med"},{"issue":"6","key":"10.1016\/j.jare.2025.03.046_b1385","doi-asserted-by":"crossref","DOI":"10.3390\/nu13061902","article-title":"The probiotic strain H. alvei HA4597(\u00ae) improves weight loss in overweight subjects under moderate hypocaloric diet: a proof-of-concept, multicenter randomized, double-blind placebo-controlled study","volume":"13","author":"D\u00e9chelotte","year":"2021","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.jare.2025.03.046_b1390","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1038\/s41366-019-0515-9","article-title":"Commensal Hafnia alvei strain reduces food intake and fat mass in obese mice-a new potential probiotic for appetite and body weight management","volume":"44","author":"Legrand","year":"2020","journal-title":"Int J Obes (Lond)"},{"issue":"10278","key":"10.1016\/j.jare.2025.03.046_b1395","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S0140-6736(21)00213-0","article-title":"Semaglutide 2\u00b74 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial","volume":"397","author":"Davies","year":"2021","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/j.jare.2025.03.046_b1400","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25084346","article-title":"Assessment of thyroid carcinogenic risk and safety profile of GLP1-RA semaglutide (Ozempic) therapy for diabetes mellitus and obesity: a systematic literature review","volume":"25","author":"Feier","year":"2024","journal-title":"Int J Mol Sci"},{"issue":"12","key":"10.1016\/j.jare.2025.03.046_b1405","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1007\/s00228-024-03755-w","article-title":"The cost-effectiveness analysis of semaglutide for the treatment of adult and adolescent patients with overweight and obesity: a systematic review","volume":"80","author":"Asiabar","year":"2024","journal-title":"Eur J Clin Pharmacol"}],"container-title":["Journal of Advanced Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123225002061?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123225002061?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T08:58:50Z","timestamp":1778835530000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2090123225002061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":281,"alternative-id":["S2090123225002061"],"URL":"https:\/\/doi.org\/10.1016\/j.jare.2025.03.046","relation":{},"ISSN":["2090-1232"],"issn-type":[{"value":"2090-1232","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comprehensive insights into emerging advances in the Neurobiology of anorexia","name":"articletitle","label":"Article Title"},{"value":"Journal of Advanced Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jare.2025.03.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V. on behalf of Cairo University.","name":"copyright","label":"Copyright"}]}}