{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T14:14:46Z","timestamp":1793196886753,"version":"4.5.0"},"reference-count":134,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T00:00:00Z","timestamp":1776556800000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32371022"],"award-info":[{"award-number":["32371022"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"publisher","award":["2022ZD0204700"],"award-info":[{"award-number":["2022ZD0204700"]}],"id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Zhejiang Province Natural Science Foundation","doi-asserted-by":"publisher","award":["LY24C090006"],"award-info":[{"award-number":["LY24C090006"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Research"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jare.2026.04.052","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T23:38:41Z","timestamp":1777073921000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["New Perspectives on oligodendrocytes: Guardians of iron homeostasis and defenders against ferroptosis"],"prefix":"10.1016","author":[{"given":"Fang","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shutian","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sitong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiantian","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengsheng","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7910-0407","authenticated-orcid":false,"given":"Xiaofeng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jare.2026.04.052_b0005","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.devcel.2015.01.016","article-title":"Dynamics and mechanisms of CNS myelination","volume":"32","author":"Bercury","year":"2015","journal-title":"Dev Cell"},{"key":"10.1016\/j.jare.2026.04.052_b0010","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1002\/glia.24426","article-title":"The committed oligodendrocyte precursor cell, a newly-defined intermediate progenitor cell type in oligodendroglial lineage","volume":"71","author":"Fang","year":"2023","journal-title":"Glia"},{"key":"10.1016\/j.jare.2026.04.052_b0015","doi-asserted-by":"crossref","first-page":"812","DOI":"10.3390\/cells9040812","article-title":"Myelin fat facts: an overview of lipids and fatty acid metabolism","volume":"9","author":"Poitelon","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.jare.2026.04.052_b0020","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.cell.2010.06.028","article-title":"Two to tango: regulation of mammalian iron metabolism","volume":"142","author":"Hentze","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.jare.2026.04.052_b0025","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1182\/blood-2007-01-068148","article-title":"Direct interorganellar transfer of iron from endosome to mitochondrion","volume":"110","author":"Sheftel","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.jare.2026.04.052_b0030","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/glia.20784","article-title":"Oligodendrocytes and myelination: the role of iron","volume":"57","author":"Todorich","year":"2009","journal-title":"Glia"},{"key":"10.1016\/j.jare.2026.04.052_b0035","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.tins.2019.03.009","article-title":"Iron, myelin, and the brain: neuroimaging meets neurobiology","volume":"42","author":"M\u00f6ller","year":"2019","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0040","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/0306-4522(84)90046-0","article-title":"The regional distribution and cellular localization of iron in the rat brain","volume":"11","author":"Hill","year":"1984","journal-title":"Neuroscience"},{"key":"10.1016\/j.jare.2026.04.052_b0045","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0022-510X(95)00206-H","article-title":"Cellular management of iron in the brain","volume":"134","author":"Connor","year":"1995","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.jare.2026.04.052_b0050","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s12868-019-0507-7","article-title":"Iron concentrations in neurons and glial cells with estimates on ferritin concentrations","volume":"20","author":"Reinert","year":"2019","journal-title":"BMC Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0055","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/cne.903380108","article-title":"Ferritin, transferrin, and iron in selected regions of the adult and aged rat brain","volume":"338","author":"Benkovic","year":"1993","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.jare.2026.04.052_b0060","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1152\/physrev.2001.81.2.871","article-title":"Biology of oligodendrocyte and myelin in the mammalian central nervous system","volume":"81","author":"Baumann","year":"2001","journal-title":"Physiol Rev"},{"key":"10.1016\/j.jare.2026.04.052_b0065","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1046\/j.1471-4159.1994.63020709.x","article-title":"Iron, transferrin, and ferritin in the rat brain during development and aging","volume":"63","author":"Roskams","year":"1994","journal-title":"J Neurochem"},{"key":"10.1016\/j.jare.2026.04.052_b0070","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/s00216-004-2697-8","article-title":"Regional distribution of manganese, iron, copper, and zinc in the rat brain during development","volume":"380","author":"Tarohda","year":"2004","journal-title":"Anal Bioanal Chem"},{"key":"10.1016\/j.jare.2026.04.052_b0075","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1159\/000073507","article-title":"Pre- and postweaning iron deficiency alters myelination in Sprague-Dawley rats","volume":"25","author":"Beard","year":"2003","journal-title":"Dev Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0080","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/ajcn\/68.3.683","article-title":"Evidence of altered central nervous system development in infants with iron deficiency anemia at 6 mo: delayed maturation of auditory brainstem responses","volume":"68","author":"Roncagliolo","year":"1998","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jare.2026.04.052_b0085","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.1002\/jnr.21709","article-title":"Effect of transferrin on hypomyelination induced by iron deficiency","volume":"86","author":"Badaracco","year":"2008","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jare.2026.04.052_b0090","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1002\/jnr.22348","article-title":"Oligodendrogenesis in iron-deficient rats: effect of apotransferrin","volume":"88","author":"Rosato-Siri","year":"2010","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jare.2026.04.052_b0095","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1203\/01.PDR.0000047657.23156.55","article-title":"Iron deficiency anemia in infancy: long-lasting effects on auditory and visual system functioning","volume":"53","author":"Algar\u00edn","year":"2003","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jare.2026.04.052_b0100","doi-asserted-by":"crossref","first-page":"649S","DOI":"10.1093\/jn\/131.2.649S","article-title":"A review of studies on the effect of iron deficiency on cognitive development in children","volume":"131","author":"Grantham-McGregor","year":"2001","journal-title":"J Nutr"},{"key":"10.1016\/j.jare.2026.04.052_b0105","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1542\/peds.71.6.877","article-title":"Effect of iron therapy on behavior performance in nonanemic, iron-deficient infants","volume":"71","author":"Oski","year":"1983","journal-title":"Pediatrics"},{"key":"10.1016\/j.jare.2026.04.052_b0110","doi-asserted-by":"crossref","first-page":"S34","DOI":"10.1301\/nr.2006.may.S34-S43","article-title":"Long-lasting neural and behavioral effects of iron deficiency in infancy","volume":"64","author":"Lozoff","year":"2006","journal-title":"Nutr Rev"},{"key":"10.1016\/j.jare.2026.04.052_b0115","doi-asserted-by":"crossref","first-page":"524S","DOI":"10.1093\/jn\/137.2.524S","article-title":"Recent evidence from human and animal studies regarding iron status and infant development","volume":"137","author":"Beard","year":"2007","journal-title":"J Nutr"},{"key":"10.1016\/j.jare.2026.04.052_b0120","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/s41580-023-00648-1","article-title":"Mechanisms controlling cellular and systemic iron homeostasis","volume":"25","author":"Galy","year":"2024","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.jare.2026.04.052_b0125","first-page":"3614","article-title":"Transferrin receptor is necessary for proper oligodendrocyte iron homeostasis and development","volume":"43","author":"Cheli","year":"2023","journal-title":"J Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0130","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1152\/physrev.00008.2013","article-title":"Systemic iron homeostasis","volume":"93","author":"Ganz","year":"2013","journal-title":"Physiol Rev"},{"key":"10.1016\/j.jare.2026.04.052_b0135","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1038\/ng1658","article-title":"Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells","volume":"37","author":"Ohgami","year":"2005","journal-title":"Nat Genet"},{"key":"10.1016\/j.jare.2026.04.052_b0140","doi-asserted-by":"crossref","first-page":"9142","DOI":"10.1523\/JNEUROSCI.1447-18.2018","article-title":"The divalent metal transporter 1 (DMT1) is required for iron uptake and normal development of oligodendrocyte progenitor cells","volume":"38","author":"Cheli","year":"2018","journal-title":"J Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0145","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1023\/A:1020702213099","article-title":"DMT1: a mammalian transporter for multiple metals","volume":"16","author":"Garrick","year":"2003","journal-title":"Biometals"},{"key":"10.1016\/j.jare.2026.04.052_b0150","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.freeradbiomed.2025.06.055","article-title":"Oligodendrocyte-specific knockout of FPN1 affects CNS myelination defects and depression-like behavior in mice","volume":"238","author":"Zhang","year":"2025","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.jare.2026.04.052_b0155","doi-asserted-by":"crossref","DOI":"10.1177\/1759091420962681","article-title":"Iron metabolism in oligodendrocytes and astrocytes, implications for myelination and remyelination","volume":"12","author":"Cheli","year":"2020","journal-title":"ASN Neuro"},{"key":"10.1016\/j.jare.2026.04.052_b0160","doi-asserted-by":"crossref","first-page":"7609","DOI":"10.1523\/JNEUROSCI.1281-20.2020","article-title":"Impaired postnatal myelination in a conditional knockout mouse for the ferritin heavy chain in oligodendroglial cells","volume":"40","author":"Wan","year":"2020","journal-title":"J Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0165","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1126\/science.2452485","article-title":"Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation","volume":"240","author":"Casey","year":"1988","journal-title":"Science"},{"key":"10.1016\/j.jare.2026.04.052_b0170","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0092-8674(04)00343-5","article-title":"Balancing acts: molecular control of mammalian iron metabolism","volume":"117","author":"Hentze","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.jare.2026.04.052_b0175","first-page":"1468","article-title":"Mammalian iron metabolism and its control by iron regulatory proteins","volume":"2012","author":"Anderson","year":"1823","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.jare.2026.04.052_b0180","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.cell.2016.12.034","article-title":"A Red carpet for iron metabolism","volume":"168","author":"Muckenthaler","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.jare.2026.04.052_b0185","doi-asserted-by":"crossref","first-page":"4713","DOI":"10.1007\/s12035-015-9389-6","article-title":"Hypoxia-induced iron accumulation in oligodendrocytes mediates apoptosis by eliciting endoplasmic reticulum stress","volume":"53","author":"Rathnasamy","year":"2016","journal-title":"Mol Neurobiol"},{"key":"10.1016\/j.jare.2026.04.052_b0190","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1159\/000064945","article-title":"Apotransferrin decreases migration and enhances differentiation of oligodendroglial progenitor cells in an in vitro system","volume":"24","author":"Paez","year":"2002","journal-title":"Dev Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0195","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.neuint.2006.02.009","article-title":"Apotransferrin decreases the response of oligodendrocyte progenitors to PDGF and inhibits the progression of the cell cycle","volume":"49","author":"Paez","year":"2006","journal-title":"Neurochem Int"},{"key":"10.1016\/j.jare.2026.04.052_b0200","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/jnr.20741","article-title":"Oligodendrocyte differentiation is increased in transferrin transgenic mice","volume":"83","author":"Sow","year":"2006","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jare.2026.04.052_b0205","first-page":"248","article-title":"Single intracerebral injection of apotransferrin in young rats induces increased myelination","volume":"16","author":"Escobar Cabrera","year":"1994","journal-title":"Dev Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0210","doi-asserted-by":"crossref","unstructured":"O.E. Escobar Cabrera, M.M. Zakin, E.F. Soto, J.M. Pasquini, Single intracranial injection of apotransferrin in young rats increases the expression of specific myelin protein mRNA, J. Neurosci. Res. 47 (1997) 603-608. doi:10.1002\/(SICI)1097-4547(19970301)47:5<603::AID-JNR10>3.0.CO;2-O.","DOI":"10.1002\/(SICI)1097-4547(19970315)47:6<603::AID-JNR5>3.0.CO;2-H"},{"key":"10.1016\/j.jare.2026.04.052_b0215","doi-asserted-by":"crossref","unstructured":"M.C. Saleh, A. Espinosa de los Monteros, G.A. de Arriba Zerpa, I. Fontaine, O. Piaud, D. Djordjijevic, et al., Myelination and motor coordination are increased in transferrin transgenic mice, J. Neurosci. Res. 72 (2003) 587-594. doi:10.1002\/jnr.10619.","DOI":"10.1002\/jnr.10619"},{"key":"10.1016\/j.jare.2026.04.052_b0220","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.expneurol.2005.12.027","article-title":"Remyelination after cuprizone-induced demyelination in the rat is stimulated by apotransferrin","volume":"198","author":"Adamo","year":"2006","journal-title":"Exp Neurol"},{"key":"10.1016\/j.jare.2026.04.052_b0225","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1182\/blood.2019002907","article-title":"Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis","volume":"136","author":"Yu","year":"2020","journal-title":"Blood"},{"key":"10.1016\/j.jare.2026.04.052_b0230","doi-asserted-by":"crossref","first-page":"6706","DOI":"10.1073\/pnas.82.19.6706","article-title":"Transferrin gene expression visualized in oligodendrocytes of the rat brain by using in situ hybridization and immunohistochemistry","volume":"82","author":"Bloch","year":"1985","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.jare.2026.04.052_b0235","doi-asserted-by":"crossref","unstructured":"A. Espinosa de los Monteros, F. Chiapelli, R.S. Fisher, J. de Vellis, Transferrin: an early marker of oligodendrocytes in culture, Int. J. Dev. Neurosci. 6 (1988) 167-175. doi:10.1016\/0736-5748(88)90042-1.","DOI":"10.1016\/0736-5748(88)90042-1"},{"key":"10.1016\/j.jare.2026.04.052_b0240","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1038\/nrneurol.2014.118","article-title":"Iron in multiple sclerosis: roles in neurodegeneration and repair","volume":"10","author":"Stephenson","year":"2014","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.jare.2026.04.052_b0245","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1002\/hep.23058","article-title":"Conditional deletion of ferritin H in mice induces loss of iron storage and liver damage","volume":"50","author":"Darshan","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.jare.2026.04.052_b0250","first-page":"274","article-title":"The expression of ferritin subunits and iron in oligodendrocytes in neonatal porcine brains","volume":"18","author":"Blissman","year":"1996","journal-title":"Dev Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0255","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/(SICI)1097-4547(19961015)46:2<187::AID-JNR6>3.0.CO;2-D","article-title":"Differential expression of the heavy-chain ferritin gene in non-adhered and adhered oligodendrocytes","volume":"46","author":"Sanyal","year":"1996","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jare.2026.04.052_b0260","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1046\/j.1471-4159.1994.63041485.x","article-title":"Hypoxia specifically and reversibly induces the synthesis of ferritin in oligodendrocytes and human oligodendrogliomas","volume":"63","author":"Qi","year":"1994","journal-title":"J Neurochem"},{"key":"10.1016\/j.jare.2026.04.052_b0265","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1002\/jnr.20207","article-title":"Effect of manipulation of iron storage, transport, or availability on myelin composition and brain iron content in three different animal models","volume":"77","author":"Ortiz","year":"2004","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jare.2026.04.052_b0270","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.cmet.2020.05.019","article-title":"Oligodendrocytes provide antioxidant defense function for neurons by secreting ferritin heavy chain","volume":"32","author":"Mukherjee","year":"2020","journal-title":"Cell Metab"},{"key":"10.1016\/j.jare.2026.04.052_b0275","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/jnr.10463","article-title":"Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress","volume":"71","author":"Thompson","year":"2003","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.jare.2026.04.052_b0280","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1007\/s00415-008-0945-0","article-title":"Increased serum ferritin levels in amyotrophic lateral sclerosis (ALS) patients","volume":"255","author":"Goodall","year":"2008","journal-title":"J Neurol"},{"key":"10.1016\/j.jare.2026.04.052_b0285","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1038\/s41418-021-00910-z","article-title":"Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis","volume":"29","author":"Wang","year":"2022","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.jare.2026.04.052_b0290","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.jare.2026.04.052_b0295","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2025.1587986","article-title":"Insights into targeted ferroptosis in mechanisms, biology, and role of Alzheimer's disease: an update","volume":"17","author":"Zhou","year":"2025","journal-title":"Front Aging Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0300","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41580-020-00324-8","article-title":"Ferroptosis: mechanisms, biology and role in disease","volume":"22","author":"Jiang","year":"2021","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.jare.2026.04.052_b0305","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.redox.2017.01.021","article-title":"Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration","volume":"12","author":"Hambright","year":"2017","journal-title":"Redox Biol"},{"key":"10.1016\/j.jare.2026.04.052_b0310","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.cell.2017.09.021","article-title":"Ferroptosis: a regulated cell death nexus linking metabolism redox biology, and disease","volume":"171","author":"Stockwell","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.jare.2026.04.052_b0315","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.1093\/brain\/awab236","article-title":"Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease","volume":"144","author":"Doppler","year":"2021","journal-title":"Brain"},{"key":"10.1016\/j.jare.2026.04.052_b0320","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1002\/alz.12282","article-title":"Regional brain iron associated with deterioration in Alzheimer's disease: a large cohort study and theoretical significance","volume":"17","author":"Ayton","year":"2021","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.jare.2026.04.052_b0325","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.cell.2013.12.010","article-title":"Regulation of ferroptotic cancer cell death by GPX4","volume":"156","author":"Yang","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.jare.2026.04.052_b0330","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1038\/ncb3064","article-title":"Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice","volume":"16","author":"Friedmann Angeli","year":"2014","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.jare.2026.04.052_b0335","doi-asserted-by":"crossref","first-page":"6241","DOI":"10.1523\/JNEUROSCI.18-16-06241.1998","article-title":"Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion","volume":"18","author":"Back","year":"1998","journal-title":"J Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0340","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1046\/j.1471-4159.1996.67031014.x","article-title":"Low glutathione and high iron govern the susceptibility of oligodendroglial precursors to oxidative stress","volume":"67","author":"Thorburne","year":"1996","journal-title":"J Neurochem"},{"key":"10.1016\/j.jare.2026.04.052_b0345","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/(SICI)1098-1136(199804)22:4<371::AID-GLIA6>3.0.CO;2-6","article-title":"Peroxide-scavenging deficit underlies oligodendrocyte susceptibility to oxidative stress","volume":"22","author":"Juurlink","year":"1998","journal-title":"Glia"},{"key":"10.1016\/j.jare.2026.04.052_b0350","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/cns.12690","article-title":"Roles of NG2-glia in ischemic stroke","volume":"23","author":"Song","year":"2017","journal-title":"CNS Neurosci Ther"},{"key":"10.1016\/j.jare.2026.04.052_b0355","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1101\/gad.344218.120","article-title":"Cell of all trades: oligodendrocyte precursor cells in synaptic, vascular, and immune function","volume":"35","author":"Akay","year":"2021","journal-title":"Genes Dev"},{"key":"10.1016\/j.jare.2026.04.052_b0360","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1002\/2211-5463.12923","article-title":"Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line","volume":"10","author":"Hoshino","year":"2020","journal-title":"FEBS Open Bio"},{"key":"10.1016\/j.jare.2026.04.052_b0365","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/s41419-022-04712-0","article-title":"Ferroptosis in oligodendrocyte progenitor cells mediates white matter injury after hemorrhagic stroke","volume":"13","author":"Shen","year":"2022","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.jare.2026.04.052_b0370","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.4103\/NRR.NRR-D-23-01540","article-title":"Perilipin-2 mediates ferroptosis in oligodendrocyte progenitor cells and myelin injury after ischemic stroke","volume":"20","author":"Yang","year":"2025","journal-title":"Neural Regen Res"},{"key":"10.1016\/j.jare.2026.04.052_b0375","doi-asserted-by":"crossref","DOI":"10.1016\/j.abb.2025.110509","article-title":"Iron and selenium: at the crossroads of development and death in oligodendrocytes","volume":"771","author":"Ma","year":"2025","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.jare.2026.04.052_b0380","doi-asserted-by":"crossref","DOI":"10.1016\/j.abb.2022.109376","article-title":"Selenoprotein I (selenoi) as a critical enzyme in the central nervous system","volume":"729","author":"Nunes","year":"2022","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.jare.2026.04.052_b0385","doi-asserted-by":"crossref","first-page":"11174","DOI":"10.3390\/ijms222011174","article-title":"Roles for selenoprotein I and ethanolamine phospholipid synthesis in T cell activation","volume":"22","author":"Ma","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jare.2026.04.052_b0390","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2024.107259","article-title":"Selenoprotein \u2160 is indispensable for ether lipid homeostasis and proper myelination","volume":"300","author":"Nunes","year":"2024","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jare.2026.04.052_b0395","doi-asserted-by":"crossref","DOI":"10.26508\/lsa.202101291","article-title":"The expression of essential selenoproteins during development requires SECIS-binding protein 2-like","volume":"5","author":"Kiledjian","year":"2022","journal-title":"Life Sci Alliance"},{"key":"10.1016\/j.jare.2026.04.052_b0400","doi-asserted-by":"crossref","first-page":"5860","DOI":"10.1523\/JNEUROSCI.2141-21.2022","article-title":"SECISBP2L-mediated selenoprotein synthesis is essential for autonomous regulation of oligodendrocyte differentiation","volume":"42","author":"Dai","year":"2022","journal-title":"J Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0405","doi-asserted-by":"crossref","unstructured":"M. Yugami, Y. Hayakawa-Yano, T. Ogasawara, K. Yokoyama, T. Furukawa, H. Hara, et al., Sbp2l contributes to oligodendrocyte maturation through translational control in Tcf7l2 signaling, iScience 26 (2023) 108451. doi:10.1016\/j.isci.2023.108451.","DOI":"10.1016\/j.isci.2023.108451"},{"key":"10.1016\/j.jare.2026.04.052_b0410","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1023\/A:1021635826032","article-title":"Turnover of myelin lipids in aging brain","volume":"28","author":"Ando","year":"2003","journal-title":"Neurochem Res"},{"key":"10.1016\/j.jare.2026.04.052_b0415","doi-asserted-by":"crossref","first-page":"3046","DOI":"10.1002\/cne.22379","article-title":"Age changes in myelinated nerve fibers of the cingulate bundle and corpus callosum in the rhesus monkey","volume":"518","author":"Bowley","year":"2010","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.jare.2026.04.052_b0420","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1038\/nn.4325","article-title":"Age-related myelin degradation burdens the clearance function of microglia during aging","volume":"19","author":"Safaiyan","year":"2016","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0425","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1038\/s41593-023-01366-9","article-title":"Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease","volume":"26","author":"Sch\u00e4ffner","year":"2023","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0430","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1093\/brain\/awae029","article-title":"Prolonged myelin deficits contribute to neuron loss and functional impairments after ischaemic stroke","volume":"147","author":"Cheng","year":"2024","journal-title":"Brain"},{"key":"10.1016\/j.jare.2026.04.052_b0435","doi-asserted-by":"crossref","first-page":"4241","DOI":"10.1093\/brain\/awaf398","article-title":"Iron on trial: recasting the role of iron in neurodegeneration","volume":"148","author":"Ayton","year":"2025","journal-title":"Brain"},{"key":"10.1016\/j.jare.2026.04.052_b0440","doi-asserted-by":"crossref","DOI":"10.1016\/j.msard.2023.104934","article-title":"Iron in multiple sclerosis-Neuropathology, immunology, and real-world considerations","volume":"78","author":"Zierfuss","year":"2023","journal-title":"Mult Scler Relat Disord"},{"key":"10.1016\/j.jare.2026.04.052_b0445","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1007\/s00401-023-02627-4","article-title":"Myeloid cell iron uptake pathways and paramagnetic rim formation in multiple sclerosis","volume":"146","author":"Hofmann","year":"2023","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.jare.2026.04.052_b0450","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s40478-025-02020-0","article-title":"Inflammation alters myeloid cell and oligodendroglial iron-handling in multiple sclerosis","volume":"13","author":"Riedl","year":"2025","journal-title":"Acta Neuropathol Commun"},{"key":"10.1016\/j.jare.2026.04.052_b0455","doi-asserted-by":"crossref","first-page":"9327","DOI":"10.1523\/JNEUROSCI.1749-20.2020","article-title":"Ferroptosis Mediates cuprizone-induced loss of oligodendrocytes and demyelination","volume":"40","author":"Jhelum","year":"2020","journal-title":"J Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0460","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1111\/jnc.14604","article-title":"Reduced expression of the ferroptosis inhibitor glutathione peroxidase-4 in multiple sclerosis and experimental autoimmune encephalomyelitis","volume":"148","author":"Hu","year":"2019","journal-title":"J Neurochem"},{"key":"10.1016\/j.jare.2026.04.052_b0465","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1038\/s41418-023-01195-0","article-title":"Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression","volume":"30","author":"Van San","year":"2023","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.jare.2026.04.052_b0470","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103463","article-title":"AKRs confer oligodendrocytes resistance to differentiation-stimulated ferroptosis","volume":"79","author":"Saverio","year":"2025","journal-title":"Redox Biol"},{"key":"10.1016\/j.jare.2026.04.052_b0475","doi-asserted-by":"crossref","first-page":"12890","DOI":"10.1038\/s41598-021-92369-8","article-title":"Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice","volume":"11","author":"Chen","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.jare.2026.04.052_b0480","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.stem.2019.09.003","article-title":"Oligodendrocyte death in Pelizaeus-merzbacher disease is rescued by iron chelation","volume":"25","author":"Nobuta","year":"2019","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.jare.2026.04.052_b0485","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1471-4159.1989.tb09150.x","article-title":"Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains","volume":"52","author":"Riederer","year":"1989","journal-title":"J Neurochem"},{"key":"10.1016\/j.jare.2026.04.052_b0490","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1111\/j.1471-4159.1989.tb07264.x","article-title":"Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson\u2019s disease","volume":"52","author":"Dexter","year":"1989","journal-title":"J Neurochem"},{"key":"10.1016\/j.jare.2026.04.052_b0495","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1148\/radiol.10100495","article-title":"Quantitative MR imaging of brain iron: a postmortem validation study","volume":"257","author":"Langkammer","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.jare.2026.04.052_b0500","doi-asserted-by":"crossref","first-page":"17013","DOI":"10.1038\/nrdp.2017.13","article-title":"Parkinson disease","volume":"3","author":"Poewe","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.jare.2026.04.052_b0505","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1093\/brain\/awab446","article-title":"Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state","volume":"145","author":"Smaji\u0107","year":"2022","journal-title":"Brain"},{"key":"10.1016\/j.jare.2026.04.052_b0510","doi-asserted-by":"crossref","first-page":"890","DOI":"10.3174\/ajnr.A2860","article-title":"White matter alteration of the cingulum in Parkinson disease with and without dementia: evaluation by diffusion tensor tract-specific analysis","volume":"33","author":"Kamagata","year":"2012","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.jare.2026.04.052_b0515","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.nicl.2017.07.011","article-title":"Diffusion tensor imaging in Parkinson\u2019s disease: review and meta-analysis","volume":"16","author":"Atkinson-Clement","year":"2017","journal-title":"Neuroimage Clin"},{"key":"10.1016\/j.jare.2026.04.052_b0520","doi-asserted-by":"crossref","first-page":"3591","DOI":"10.1523\/JNEUROSCI.3439-14.2015","article-title":"Parkinson\u2019s disease iron deposition caused by nitric oxide-induced loss of \u03b2-amyloid precursor protein","volume":"35","author":"Ayton","year":"2015","journal-title":"J Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0525","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/sj.mp.4001937","article-title":"The 5\u2019-untranslated region of Parkinson\u2019s disease alpha-synuclein messenger RNA contains a predicted iron responsive element","volume":"12","author":"Friedlich","year":"2007","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.jare.2026.04.052_b0530","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/900a5247-7d03-4686-a544-5f7f64c0aac5","article-title":"Alpha-synuclein is a cellular ferrireductase","volume":"6","author":"Davies","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jare.2026.04.052_b0535","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/j.1440-1789.2006.00713.x","article-title":"Cellular pathology in multiple system atrophy","volume":"26","author":"Wakabayashi","year":"2006","journal-title":"Neuropathology"},{"key":"10.1016\/j.jare.2026.04.052_b0540","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s004010050001","article-title":"Sequestration of iron by Lewy bodies in Parkinson\u2019s disease","volume":"100","author":"Castellani","year":"2000","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.jare.2026.04.052_b0545","doi-asserted-by":"crossref","first-page":"5541","DOI":"10.2147\/IJN.S200490","article-title":"Alzheimer's disease: pathogenesis, diagnostics, and therapeutics","volume":"14","author":"Tiwari","year":"2019","journal-title":"Int J Nanomed"},{"key":"10.1016\/j.jare.2026.04.052_b0550","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00308809","article-title":"Neuropathological stageing of Alzheimer-related changes","volume":"82","author":"Braak","year":"1991","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.jare.2026.04.052_b0555","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1046\/j.1471-4159.2000.0740270.x","article-title":"In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals","volume":"74","author":"Sayre","year":"2000","journal-title":"J Neurochem"},{"key":"10.1016\/j.jare.2026.04.052_b0560","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1148\/radiol.2020201603","article-title":"Quantitative susceptibility mapping of brain iron and \u03b2-Amyloid in MRI and PET relating to cognitive performance in cognitively normal older adults","volume":"298","author":"Chen","year":"2021","journal-title":"Radiology"},{"key":"10.1016\/j.jare.2026.04.052_b0565","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1523\/JNEUROSCI.1907-15.2016","article-title":"In Vivo MRI mapping of brain iron deposition across the adult lifespan","volume":"36","author":"Acosta-Cabronero","year":"2016","journal-title":"J Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0570","doi-asserted-by":"crossref","first-page":"6984","DOI":"10.1002\/alz.14188","article-title":"Distinct regional vulnerability to A\u03b2 and iron accumulation in post mortem AD brains","volume":"20","author":"Yao","year":"2024","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.jare.2026.04.052_b0575","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1038\/s41586-019-1195-2","article-title":"Single-cell transcriptomic analysis of Alzheimer's disease","volume":"570","author":"Mathys","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.jare.2026.04.052_b0580","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.cell.2020.06.038","article-title":"Spatial Transcriptomics and in situ sequencing to study Alzheimer's disease","author":"Chen","year":"2020","journal-title":"Cell 182"},{"key":"10.1016\/j.jare.2026.04.052_b0585","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/s41591-019-0695-9","article-title":"Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease","volume":"26","author":"Zhou","year":"2020","journal-title":"Nat Med"},{"key":"10.1016\/j.jare.2026.04.052_b0590","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1038\/s41593-022-01104-7","article-title":"A shared disease-associated oligodendrocyte signature among multiple CNS pathologies","volume":"25","author":"Kenigsbuch","year":"2022","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.jare.2026.04.052_b0595","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/s41586-025-09063-2","article-title":"Maternal iron deficiency causes male-to-female sex reversal in mouse embryos","volume":"643","author":"Okashita","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.jare.2026.04.052_b0600","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1177\/1352458507078916","article-title":"Deferiprone, an orally deliverable iron chelator, ameliorates experimental autoimmune encephalomyelitis","volume":"13","author":"Mitchell","year":"2007","journal-title":"Mult Scler"},{"key":"10.1016\/j.jare.2026.04.052_b0605","doi-asserted-by":"crossref","first-page":"11664","DOI":"10.1038\/s41598-019-48087-3","article-title":"Dexras1 deletion and iron chelation promote neuroprotection in experimental optic neuritis","volume":"9","author":"Khan","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.jare.2026.04.052_b0610","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/s00210-024-03314-1","article-title":"Deferiprone promoted remyelination and functional recovery through enhancement of oligodendrogenesis in experimental demyelination animal model","volume":"398","author":"Rayatpour","year":"2025","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.1016\/j.jare.2026.04.052_b0615","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1056\/NEJMoa2209254","article-title":"Trial of deferiprone in Parkinson\u2019s disease","volume":"387","author":"Devos","year":"2022","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jare.2026.04.052_b0620","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.3390\/antiox10081270","article-title":"Targeting pro-oxidant iron with deferoxamine as a treatment for ischemic stroke: safety and optimal dose selection in a randomized clinical trial","volume":"10","author":"Mill\u00e1n","year":"2021","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.jare.2026.04.052_b0625","doi-asserted-by":"crossref","first-page":"7533","DOI":"10.2147\/IJN.S516316","article-title":"Platelet membrane-based nanoparticles for targeted delivery of deferoxamine to alleviate brain injury induced by ischemic stroke","volume":"20","author":"Wang","year":"2025","journal-title":"Int J Nanomed"},{"key":"10.1016\/j.jare.2026.04.052_b0630","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuint.2025.105934","article-title":"TDP-43 transports ferritin heavy chain mRNA to regulate oxidative stress in neuronal axons","volume":"184","author":"Jinno","year":"2025","journal-title":"Neurochem Int"},{"key":"10.1016\/j.jare.2026.04.052_b0635","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2023.137314","article-title":"Selenium mitigates ferroptosis-mediated dopaminergic cell death by regulating the Nrf2\/GPX4 pathway","volume":"810","author":"Jin Jung","year":"2023","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.jare.2026.04.052_b0640","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1016\/j.cell.2019.03.032","article-title":"Selenium drives a transcriptional adaptive program to block ferroptosis and treat stroke","volume":"177","author":"Alim","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.jare.2026.04.052_b0645","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103268","article-title":"BSA-stabilized selenium nanoparticles ameliorate intracerebral hemorrhage\u2019s-like pathology by inhibiting ferroptosis-mediated neurotoxicology via Nrf2\/GPX4 axis activation","volume":"75","author":"Li","year":"2024","journal-title":"Redox Biol"},{"key":"10.1016\/j.jare.2026.04.052_b0650","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1002\/ana.25356","article-title":"N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice","volume":"84","author":"Karuppagounder","year":"2018","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jare.2026.04.052_b0655","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1080\/15384101.2022.2155016","article-title":"Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2\/SLC7A11\/HO-1 axis","volume":"22","author":"Qi","year":"2023","journal-title":"Cell Cycle"},{"key":"10.1016\/j.jare.2026.04.052_b0660","doi-asserted-by":"crossref","first-page":"4599","DOI":"10.3390\/nu14214599","article-title":"The ferroptosis inhibitor liproxstatin-1 ameliorates LPS-induced cognitive impairment in mice","volume":"14","author":"Li","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.jare.2026.04.052_b0665","doi-asserted-by":"crossref","first-page":"20180","DOI":"10.1038\/s41598-024-70926-1","article-title":"UAMC-3203 inhibits ferroptosis and promotes functional recovery in rats with spinal cord injury","volume":"14","author":"Kan","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.jare.2026.04.052_b0670","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/nchembio.2239","article-title":"ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition","volume":"13","author":"Doll","year":"2017","journal-title":"Nat Chem Biol"}],"container-title":["Journal of Advanced Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123226003565?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2090123226003565?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T17:14:16Z","timestamp":1782494056000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2090123226003565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":134,"alternative-id":["S2090123226003565"],"URL":"https:\/\/doi.org\/10.1016\/j.jare.2026.04.052","relation":{},"ISSN":["2090-1232"],"issn-type":[{"value":"2090-1232","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"New Perspectives on oligodendrocytes: Guardians of iron homeostasis and defenders against ferroptosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Advanced Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jare.2026.04.052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier B.V. on behalf of Cairo University.","name":"copyright","label":"Copyright"}]}}