{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T11:47:03Z","timestamp":1782560823070,"version":"3.54.5"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T00:00:00Z","timestamp":1781913600000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005230","name":"Chongqing Natural Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005230","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Advanced Research"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.jare.2026.06.018","type":"journal-article","created":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T22:09:59Z","timestamp":1782079799000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Physical exercise mitigates amyloid beta-driven muscle degeneration in Alzheimer\u2019s disease"],"prefix":"10.1016","author":[{"given":"Ling-Ling","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Xi","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Huan","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Heng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Han","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Xing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Hui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng-Xi","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Le","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan-Chuan","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gong-Wei","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0292-2792","authenticated-orcid":false,"given":"Xiu-Qing","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jare.2026.06.018_b0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2022.108966","article-title":"Exploring the dual character of metformin in Alzheimer's disease","volume":"207","author":"Ning","year":"2022","journal-title":"Neuropharmacology"},{"issue":"1","key":"10.1016\/j.jare.2026.06.018_b0010","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1186\/s40001-024-02006-z","article-title":"Efficacy of selective serotonin reuptake inhibitors-related antidepressants in Alzheimer's disease: a meta-analysis","volume":"29","author":"Wang","year":"2024","journal-title":"Eur J Med Res"},{"key":"10.1016\/j.jare.2026.06.018_b0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2023.102113","article-title":"Recent advancement in therapeutic strategies for Alzheimer's disease: insights from clinical trials","volume":"92","author":"Khan","year":"2023","journal-title":"Ageing Res Rev"},{"issue":"10","key":"10.1016\/j.jare.2026.06.018_b0020","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1038\/nrneurol.2017.111","article-title":"A systemic view of Alzheimer disease - insights from amyloid-beta metabolism beyond the brain","volume":"13","author":"Wang","year":"2017","journal-title":"Nat Rev Neurol"},{"issue":"11","key":"10.1016\/j.jare.2026.06.018_b0025","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci14111054","article-title":"Alzheimer's disease: understanding motor impairments","volume":"14","author":"Andrade-Guerrero","year":"2024","journal-title":"Brain Sci"},{"issue":"6","key":"10.1016\/j.jare.2026.06.018_b0030","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1007\/s12603-016-0798-7","article-title":"Frailty in relation to the risk of Alzheimer's disease, dementia, and death in older chinese adults: a seven-year prospective study","volume":"21","author":"Wang","year":"2017","journal-title":"J Nutr Health Aging"},{"issue":"3","key":"10.1016\/j.jare.2026.06.018_b0035","doi-asserted-by":"crossref","first-page":"251","DOI":"10.3988\/jcn.2022.0219","article-title":"Relationships of fall risk with Frailty, Sarcopenia, and balance disturbances in mild-to-moderate Alzheimer's disease","volume":"19","author":"Guner Oytun","year":"2023","journal-title":"J Clin Neurol"},{"issue":"7","key":"10.1016\/j.jare.2026.06.018_b0040","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.jamda.2018.03.009","article-title":"Predictors of falls and fractures leading to hospitalization in people with dementia: a representative cohort study","volume":"19","author":"Sharma","year":"2018","journal-title":"J Am Med Dir Assoc"},{"issue":"1","key":"10.1016\/j.jare.2026.06.018_b0045","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1186\/s12877-024-05589-8","article-title":"Evaluation of Sarcopenia screening indices as predictors of mortality in older patients with Alzheimer's disease","volume":"24","author":"Song","year":"2024","journal-title":"BMC Geriatr"},{"issue":"4","key":"10.1016\/j.jare.2026.06.018_b0050","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1002\/jcsm.13482","article-title":"Accelerated sarcopenia precedes learning and memory impairments in the P301S mouse model of tauopathies and Alzheimer's disease","volume":"15","author":"Longo","year":"2024","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.jare.2026.06.018_b0055","article-title":"Neuromuscular dysfunction precedes cognitive impairment in a mouse model of Alzheimer's disease","volume":"5(1):zqad066","author":"Brisendine","year":"2024","journal-title":"Function (Oxf)"},{"issue":"1","key":"10.1016\/j.jare.2026.06.018_b0060","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41392-025-02329-1","article-title":"Organ cross-talk: molecular mechanisms, biological functions, and therapeutic interventions for diseases","volume":"11","author":"Che","year":"2026","journal-title":"Signal Transduct Target Ther"},{"issue":"2","key":"10.1016\/j.jare.2026.06.018_b0065","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s00395-026-01163-y","article-title":"Amyloid beta 42 disrupts cardiac function in Alzheimer's disease mice via SLC31A1 upregulation-mediated cuproptosis","volume":"121","author":"Xiong","year":"2026","journal-title":"Basic Res Cardiol"},{"issue":"20","key":"10.1016\/j.jare.2026.06.018_b0070","article-title":"Amyloid beta instigates cardiac neurotrophic signaling impairment, driving Alzheimer's associated heart disease","volume":"13","author":"Elia","year":"2026","journal-title":"Adv Sci (Weinh)"},{"issue":"12","key":"10.1016\/j.jare.2026.06.018_b0075","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1172\/JCI10498","article-title":"Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier","volume":"106","author":"Shibata","year":"2000","journal-title":"J Clin Invest"},{"issue":"6","key":"10.1016\/j.jare.2026.06.018_b0080","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1016\/S0002-9440(10)65682-9","article-title":"Amyloid-beta deposition in skeletal muscle of transgenic mice: possible model of inclusion body myopathy","volume":"153","author":"Fukuchi","year":"1998","journal-title":"Am J Pathol"},{"issue":"5","key":"10.1016\/j.jare.2026.06.018_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.lanhl.2025.100715","article-title":"Blood biomarkers of Alzheimer's disease and 12-year muscle strength trajectories in community-dwelling older adults: a cohort study","volume":"6","author":"Ornago","year":"2025","journal-title":"Lancet Healthy Longev"},{"issue":"3","key":"10.1016\/j.jare.2026.06.018_b0090","doi-asserted-by":"crossref","first-page":"291","DOI":"10.14283\/jfa.2022.17","article-title":"Grip strength, gait speed and plasma markers of neurodegeneration in asymptomatic middle-aged and older adults","volume":"11","author":"Jacob","year":"2022","journal-title":"J Frailty Aging"},{"key":"10.1016\/j.jare.2026.06.018_b0095","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2022.876816","article-title":"Age related changes in muscle mass and force generation in the triple transgenic (3xTgAD) mouse model of Alzheimer's disease","volume":"14","author":"Xu","year":"2022","journal-title":"Front Aging Neurosci"},{"issue":"2","key":"10.1016\/j.jare.2026.06.018_b0100","doi-asserted-by":"crossref","first-page":"100","DOI":"10.2174\/1567205012666150204124852","article-title":"Age-dependent biochemical dysfunction in skeletal muscle of triple-transgenic mouse model of Alzheimer;s disease","volume":"12","author":"Monteiro-Cardoso","year":"2015","journal-title":"Curr Alzheimer Res"},{"issue":"8","key":"10.1016\/j.jare.2026.06.018_b0105","article-title":"A novel RAGE modulator induces soluble RAGE to reduce BACE1 expression in Alzheimer's disease","volume":"12","author":"Baek","year":"2025","journal-title":"Adv Sci (Weinh)"},{"key":"10.1016\/j.jare.2026.06.018_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2023.102134","article-title":"GLP-1\/Sigma\/RAGE receptors: an evolving picture of Alzheimer's disease pathology and treatment","volume":"93","author":"Neha","year":"2024","journal-title":"Ageing Res Rev"},{"issue":"1","key":"10.1016\/j.jare.2026.06.018_b0115","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1186\/s12974-020-01981-4","article-title":"Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE\/NF-kappaB signaling pathway in vivo and in vitro","volume":"17","author":"Ding","year":"2020","journal-title":"J Neuroinflammation"},{"issue":"24","key":"10.1016\/j.jare.2026.06.018_b0120","doi-asserted-by":"crossref","first-page":"3923","DOI":"10.1007\/s00018-009-0121-4","article-title":"Ectodomain shedding of the receptor for advanced glycation end products: a novel therapeutic target for Alzheimer's disease","volume":"66","author":"Zhang","year":"2009","journal-title":"Cell Mol Life Sci"},{"issue":"1","key":"10.1016\/j.jare.2026.06.018_b0125","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s11481-024-10120-2","article-title":"Cornuside ameliorates cognitive impairments via RAGE\/TXNIP\/NF-kappaB signaling in Abeta(1-42) induced Alzheimer's disease mice","volume":"19","author":"Lian","year":"2024","journal-title":"J Neuroimmune Pharmacol"},{"issue":"1","key":"10.1016\/j.jare.2026.06.018_b0130","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/s41591-018-0275-4","article-title":"Exercise-linked FNDC5\/irisin rescues synaptic plasticity and memory defects in Alzheimer's models","volume":"25","author":"Lourenco","year":"2019","journal-title":"Nat Med"},{"issue":"2","key":"10.1016\/j.jare.2026.06.018_b0135","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jshs.2023.07.003","article-title":"Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain","volume":"13","author":"Norevik","year":"2024","journal-title":"J Sport Health Sci"},{"issue":"3","key":"10.1016\/j.jare.2026.06.018_b0140","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.cmet.2017.02.009","article-title":"Enhanced protein translation underlies improved metabolic and physical adaptations to different exercise training modes in young and old humans","volume":"25","author":"Robinson","year":"2017","journal-title":"Cell Metab"},{"issue":"5","key":"10.1016\/j.jare.2026.06.018_b0145","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1113\/jphysiol.2011.224725","article-title":"Physiological adaptations to low-volume, high-intensity interval training in health and disease","volume":"590","author":"Gibala","year":"2012","journal-title":"J Physiol"},{"key":"10.1016\/j.jare.2026.06.018_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2025.102816","article-title":"Exerkines: potential regulators of diabetic cardiomyopathy","volume":"110","author":"Yu","year":"2025","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.jare.2026.06.018_b0155","article-title":"Serpina1e mediates the exercise-induced enhancement of hippocampal memory in male mice","author":"Kim","year":"2026","journal-title":"Nat Commun"},{"issue":"10","key":"10.1016\/j.jare.2026.06.018_b0160","doi-asserted-by":"crossref","first-page":"2738","DOI":"10.1016\/j.celrep.2019.02.014","article-title":"Exercise alleviates obesity-induced metabolic dysfunction via enhancing FGF21 sensitivity in adipose tissues","volume":"26","author":"Geng","year":"2019","journal-title":"Cell Rep"},{"key":"10.1016\/j.jare.2026.06.018_b0165","article-title":"Activated hepatic stellate cells maintain liver bile acid homeostasis through paracrine FGF10\/FGFR2 signaling","author":"Li","year":"2026","journal-title":"J Hepatol"},{"issue":"5","key":"10.1016\/j.jare.2026.06.018_b0170","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.metabol.2016.02.009","article-title":"Exercise-stimulated FGF23 promotes exercise performance via controlling the excess reactive oxygen species production and enhancing mitochondrial function in skeletal muscle","volume":"65","author":"Li","year":"2016","journal-title":"Metabolism"},{"issue":"1","key":"10.1016\/j.jare.2026.06.018_b0175","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1186\/s12877-025-06269-x","article-title":"Reproducibility and validity of adapted clinical tests for the assessment of muscle strength in community-dwelling older adults living with Alzheimer's disease","volume":"25","author":"de Oliveira","year":"2025","journal-title":"BMC Geriatr"},{"issue":"10","key":"10.1016\/j.jare.2026.06.018_b0180","doi-asserted-by":"crossref","first-page":"3434","DOI":"10.7150\/thno.81951","article-title":"High-intensity interval training ameliorates Alzheimer's disease-like pathology by regulating astrocyte phenotype-associated AQP4 polarization","volume":"13","author":"Feng","year":"2023","journal-title":"Theranostics"},{"issue":"D1","key":"10.1016\/j.jare.2026.06.018_b0185","doi-asserted-by":"crossref","first-page":"D380","DOI":"10.1093\/nar\/gkx1013","article-title":"TRRUST v2: an expanded reference database of human and mouse transcriptional regulatory interactions","volume":"46","author":"Han","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jare.2026.06.018_b0190","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/1471-2105-14-128","article-title":"Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool","volume":"14","author":"Chen","year":"2013","journal-title":"BMC Bioinf"},{"issue":"W1","key":"10.1016\/j.jare.2026.06.018_b0195","doi-asserted-by":"crossref","first-page":"W90","DOI":"10.1093\/nar\/gkw377","article-title":"Enrichr: a comprehensive gene set enrichment analysis web server 2016 update","volume":"44","author":"Kuleshov","year":"2016","journal-title":"Nucleic Acids Res"},{"issue":"3","key":"10.1016\/j.jare.2026.06.018_b0200","doi-asserted-by":"crossref","first-page":"e90","DOI":"10.1002\/cpz1.90","article-title":"Gene set knowledge discovery with enrichr","volume":"1","author":"Xie","year":"2021","journal-title":"Curr Protoc"},{"issue":"12","key":"10.1016\/j.jare.2026.06.018_b0205","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25126766","article-title":"Behaviour hallmarks in Alzheimer's disease 5xFAD mouse model","volume":"25","author":"Padua","year":"2024","journal-title":"Int J Mol Sci"},{"issue":"3","key":"10.1016\/j.jare.2026.06.018_b0210","doi-asserted-by":"crossref","DOI":"10.1111\/gbb.12538","article-title":"Age-related deterioration of motor function in male and female 5xFAD mice from 3 to 16 months of age","volume":"19","author":"O'Leary","year":"2020","journal-title":"Genes Brain Behav"},{"issue":"1","key":"10.1016\/j.jare.2026.06.018_b0215","doi-asserted-by":"crossref","first-page":"7448","DOI":"10.1038\/s41598-025-90624-w","article-title":"AKT activation triggers Rab14-mediated ADAM10 translocation to the cell surface in human aortic endothelial cells","volume":"15","author":"Baek","year":"2025","journal-title":"Sci Rep"},{"issue":"10","key":"10.1016\/j.jare.2026.06.018_b0220","doi-asserted-by":"crossref","first-page":"e3090","DOI":"10.1038\/cddis.2017.490","article-title":"Neuron and microglia\/macrophage-derived FGF10 activate neuronal FGFR2\/PI3K\/Akt signaling and inhibit microglia\/macrophages TLR4\/NF-kappaB-dependent neuroinflammation to improve functional recovery after spinal cord injury","volume":"8","author":"Chen","year":"2017","journal-title":"Cell Death Dis"},{"issue":"9","key":"10.1016\/j.jare.2026.06.018_b0225","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci11091245","article-title":"Peripheral nerve impairment in a mouse model of Alzheimer's disease","volume":"11","author":"Torcinaro","year":"2021","journal-title":"Brain Sci"},{"issue":"2","key":"10.1016\/j.jare.2026.06.018_b0230","doi-asserted-by":"crossref","DOI":"10.1111\/cns.70221","article-title":"Effects of pretreatment with coenzyme Q10 (CoQ10) and high-intensity interval training (HIIT) on FNDC5, Irisin, and BDNF levels, and amyloid-beta (Abeta) plaque formation in the hippocampus of abeta-induced Alzheimer's disease rats","volume":"31","author":"Puoyan-Majd","year":"2025","journal-title":"CNS Neurosci Ther"},{"issue":"13","key":"10.1016\/j.jare.2026.06.018_b0235","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph18137201","article-title":"Evidence-based effects of high-intensity interval training on exercise capacity and health: a review with historical perspective","volume":"18","author":"Atakan","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.jare.2026.06.018_b0240","article-title":"Effects of high-intensity interval training and moderate-intensity continuous training on mitochondrial dynamics in human skeletal muscle","volume":"16","author":"Li","year":"2025","journal-title":"Front Physiol"},{"issue":"2","key":"10.1016\/j.jare.2026.06.018_b0245","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1097\/JES.0b013e318168ec1f","article-title":"Metabolic adaptations to short-term high-intensity interval training: a little pain for a lot of gain?","volume":"36","author":"Gibala","year":"2008","journal-title":"Exerc Sport Sci Rev"},{"issue":"9","key":"10.1016\/j.jare.2026.06.018_b0250","doi-asserted-by":"crossref","DOI":"10.1111\/acel.13937","article-title":"Fibroblast growth factor 10 ameliorates neurodegeneration in mouse and cellular models of Alzheimer's disease via reducing tau hyperphosphorylation and neuronal apoptosis","volume":"22","author":"Guo","year":"2023","journal-title":"Aging Cell"},{"issue":"1","key":"10.1016\/j.jare.2026.06.018_b0255","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1186\/s12916-025-04168-x","article-title":"Lactate links exercise to synaptic protection and cognitive enhancement in Alzheimer's disease models","volume":"23","author":"Han","year":"2025","journal-title":"BMC Med"},{"issue":"3","key":"10.1016\/j.jare.2026.06.018_b0260","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/s43587-026-01075-5","article-title":"Exercise alleviates cognitive dysfunction in Alzheimer's disease mice via skeletal muscle-derived extracellular vesicles that enhance plaque clearance by microglia","volume":"6","author":"Lin","year":"2026","journal-title":"Nat Aging"},{"issue":"5","key":"10.1016\/j.jare.2026.06.018_b0265","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1001\/jamaneurol.2026.0359","article-title":"Effects of exercise and intensive vascular risk reduction on cognitive function in older adults: a randomized clinical trial","volume":"83","author":"Zhang","year":"2026","journal-title":"JAMA Neurol"}],"container-title":["Journal of Advanced Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S209012322600500X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S209012322600500X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T11:28:38Z","timestamp":1782559718000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S209012322600500X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":53,"alternative-id":["S209012322600500X"],"URL":"https:\/\/doi.org\/10.1016\/j.jare.2026.06.018","relation":{},"ISSN":["2090-1232"],"issn-type":[{"value":"2090-1232","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Physical exercise mitigates amyloid beta-driven muscle degeneration in Alzheimer\u2019s disease","name":"articletitle","label":"Article Title"},{"value":"Journal of Advanced Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jare.2026.06.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V. on behalf of Cairo University.","name":"copyright","label":"Copyright"}]}}