{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:30:45Z","timestamp":1762079445629,"version":"build-2065373602"},"reference-count":87,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Society of Hypertension"],"published-print":{"date-parts":[[2014,10]]},"DOI":"10.1016\/j.jash.2014.06.005","type":"journal-article","created":{"date-parts":[[2014,7,15]],"date-time":"2014-07-15T17:31:54Z","timestamp":1405445514000},"page":"743-757","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"title":["Detection, evaluation, and treatment of severe and resistant hypertension"],"prefix":"10.1016","volume":"8","author":[{"given":"William B.","family":"White","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Rick","family":"Turner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenic A.","family":"Sica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John D.","family":"Bisognano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Calhoun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond R.","family":"Townsend","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert D.","family":"Aronow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak L.","family":"Bhatt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George L.","family":"Bakris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jash.2014.06.005_bib1","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1093\/eurheartj\/ehs368","article-title":"Resistant hypertension: a frequent and ominous finding among hypertensive patients with atherothrombosis","volume":"34","author":"Kumbhani","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jash.2014.06.005_bib2","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.jash.2013.07.003","article-title":"Review of the state of renal nerve ablation for patients with severe and resistant hypertension","volume":"7","author":"Gulati","year":"2013","journal-title":"J Am Soc Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib3","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1056\/NEJMoa1402670","article-title":"A controlled trial of renal denervation for resistant hypertension","volume":"370","author":"Bhatt","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jash.2014.06.005_bib4","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s11906-009-0013-x","article-title":"Baroreflex device therapy in the treatment of hypertension","volume":"11","author":"Uppuluri","year":"2009","journal-title":"Curr Hypertens Rep"},{"key":"10.1016\/j.jash.2014.06.005_bib5","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1161\/HYPERTENSIONAHA.108.119859","article-title":"Chronic lowering of blood pressure by carotid baroreflex activation: mechanisms and potential for hypertension therapy","volume":"57","author":"Lohmeier","year":"2011","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib6","doi-asserted-by":"crossref","first-page":"587194","DOI":"10.1155\/2012\/587194","article-title":"Baroreflex activation therapy for the treatment of drug-resistant hypertension: new developments","volume":"2012","author":"Alnima","year":"2012","journal-title":"Cardiol Res Pract"},{"key":"10.1016\/j.jash.2014.06.005_bib7","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1161\/HYPERTENSIONAHA.108.189141","article-title":"Resistant hypertension: diagnosis, evaluation, and treatment\u2013a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research","volume":"51","author":"Calhoun","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib8","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1161\/01.HYP.0000107251.49515.c2","article-title":"Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure","volume":"42","author":"Chobanian","year":"2003","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib9","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1097\/HJH.0b013e3281fc975a","article-title":"2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)","volume":"25","author":"Mancia","year":"2007","journal-title":"J Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib10","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1097\/01.hjh.0000431740.32696.cc","article-title":"2013 ESH\/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)","volume":"31","author":"Mancia","year":"2013","journal-title":"J Hypertens"},{"issue":"Suppl R","key":"10.1016\/j.jash.2014.06.005_bib11","doi-asserted-by":"crossref","first-page":"R58","DOI":"10.4244\/EIJV9SRA11","article-title":"Updated ESH position paper on interventional therapy of resistant hypertension","volume":"9","author":"Schmieder","year":"2013","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jash.2014.06.005_bib12","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1161\/HYPERTENSIONAHA.111.170118","article-title":"High prevalence of white-coat hypertension in Spanish resistant hypertensive patients","volume":"57","author":"Elliott","year":"2011","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib13","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1111\/jch.12200","article-title":"Diagnosis and treatment of resistant hypertension: the critical role of ambulatory blood pressure monitoring","volume":"15","author":"Turner","year":"2013","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"10.1016\/j.jash.2014.06.005_bib14","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1001\/jama.2010.650","article-title":"US trends in prevalence, awareness, treatment, and control of hypertension, 1988-2008","volume":"303","author":"Egan","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.jash.2014.06.005_bib15","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1161\/CIRCULATIONAHA.111.030189","article-title":"Uncontrolled and apparent treatment resistant hypertension in the United States, 1988 to 2008","volume":"124","author":"Egan","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.jash.2014.06.005_bib16","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.jash.2013.06.004","article-title":"Characteristics, drug combinations and dosages of primary care patients with uncontrolled ambulatory blood pressure and high medication adherence","volume":"7","author":"Grigoryan","year":"2013","journal-title":"J Am Soc Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib17","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1161\/HYPERTENSIONAHA.113.01448","article-title":"Prevalence of optimal treatment regimens in patients with apparent treatment-resistant hypertension based on office blood pressure in a community-based practice network","volume":"62","author":"Egan","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib18","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/HJH.0000000000000023","article-title":"Dynamic resistant hypertension patterns as predictors of cardiovascular morbidity: a 4-year prospective study","volume":"32","author":"Tsioufis","year":"2014","journal-title":"J Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib19","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.jash.2013.05.006","article-title":"Prevalence and characteristics of pseudohypertension in patients with \u201cresistant hypertension\u201d","volume":"7","author":"Kleman","year":"2013","journal-title":"J Am Soc Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib20","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.jash.2013.07.007","article-title":"Apparent and true resistant hypertension: why not the same?","volume":"7","author":"Calhoun","year":"2013","journal-title":"J Am Soc Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib21","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1097\/HJH.0b013e32831b9e6b","article-title":"Use of automated office blood pressure measurement to reduce the white coat response","volume":"27","author":"Myers","year":"2009","journal-title":"J Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib22","doi-asserted-by":"crossref","first-page":"185","DOI":"10.7326\/0003-4819-159-3-201308060-00008","article-title":"Self-measured blood pressure monitoring in the management of hypertension: a systematic review and meta-analysis","volume":"159","author":"Uhlig","year":"2013","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jash.2014.06.005_bib23","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1097\/HJH.0b013e328363e964","article-title":"European Society of Hypertension Position Paper on ambulatory blood pressure monitoring","volume":"31","author":"O'Brien","year":"2013","journal-title":"J Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib24","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1097\/HJH.0b013e328352c3c7","article-title":"Should ambulatory blood pressure monitoring be mandatory for future studies in resistant hypertension: a perspective","volume":"30","author":"Doumas","year":"2012","journal-title":"J Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib25","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1097\/HJH.0b013e328364d3f1","article-title":"Interventional hypertension: a new hope or a new hype? The need to redefine resistant hypertension","volume":"31","author":"Campese","year":"2013","journal-title":"J Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib26","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1136\/heartjnl-2013-304238","article-title":"Size of blood pressure reduction from renal denervation: insights from meta-analysis of antihypertensive drug trials of 4121 patients with focus on trial design: the CONVERGE report","volume":"99","author":"Howard","year":"2013","journal-title":"Heart"},{"issue":"3","key":"10.1016\/j.jash.2014.06.005_bib27","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/s11906-013-0349-0","article-title":"Role of ambulatory blood pressure monitoring in resistant hypertension","volume":"15","author":"Grassi","year":"2011","journal-title":"Curr Hypertens Rep"},{"key":"10.1016\/j.jash.2014.06.005_bib28","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1093\/eurheartj\/eht154","article-title":"Expert consensus document from the European Society of Cardiology on catheter-based renal denervation","volume":"34","author":"Mahfoud","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jash.2014.06.005_bib29","first-page":"2013","article-title":"International Expert Consensus Statement: percutaneous transluminal renal denervation for the treatment of resistant hypertension","volume":"62","author":"Schlaich","year":"2013","journal-title":"JCAA"},{"key":"10.1016\/j.jash.2014.06.005_bib30","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1161\/HYPERTENSIONAHA.113.01275","article-title":"White-coat hypertension: new insights from recent studies","volume":"62","author":"Franklin","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib31","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/nrcardio.2011.115","article-title":"Diagnosis and management of patients with white-coat and masked hypertension","volume":"8","author":"Mancia","year":"2011","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jash.2014.06.005_bib32","doi-asserted-by":"crossref","unstructured":"National Institute for Health and Care Excellence. Clinical guideline 127. Hypertension: clinical management of primary hypertension in adults. August 2011. Available at: http:\/\/guidance.nice.org.uk\/CG127\/Guidance (Accessed 1st May 2014).","DOI":"10.1016\/j.ycar.2012.02.067"},{"key":"10.1016\/j.jash.2014.06.005_bib33","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1161\/CIRCULATIONAHA.107.697086","article-title":"Ambulatory blood pressure for cardiovascular risk stratification","volume":"115","author":"Verdecchia","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jash.2014.06.005_bib34","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1161\/HYPERTENSIONAHA.112.191858","article-title":"Day-night dip and early-morning surge in blood pressure in hypertension: prognostic implications","volume":"60","author":"Verdecchia","year":"2012","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib35","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1097\/00004872-200403000-00001","article-title":"Office compared with ambulatory blood pressure in assessing response to antihypertensive treatment: a meta-analysis","volume":"22","author":"Mancia","year":"2004","journal-title":"J Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib36","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1161\/CIRCULATIONAHA.112.000949","article-title":"Ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension","volume":"128","author":"Mahfoud","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.jash.2014.06.005_bib37","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1161\/HYPERTENSIONAHA.110.156976","article-title":"Divergent results using clinical and ambulatory blood pressures: report of a darusentan-resistant hypertension trial","volume":"56","author":"Bakris","year":"2010","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib38","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1161\/HYPERTENSIONAHA.111.188284","article-title":"Azilsartan medoxomil plus chlorthalidone reduces blood pressure more effectively than olmesartan plus hydrochlorothiazide in stage 2 systolic hypertension","volume":"60","author":"Cushman","year":"2012","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib39","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s40261-012-0003-7","article-title":"Long-term efficacy of olmesartan medoxomil in Chinese hypertensive patients as assessed by clinic, ambulatory and home blood pressure measurements","volume":"32","author":"Wang","year":"2012","journal-title":"Clin Drug Investig"},{"key":"10.1016\/j.jash.2014.06.005_bib40","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jash.2010.02.005","article-title":"Combination therapy in hypertension","volume":"4","author":"Gradman","year":"2010","journal-title":"J Am Soc Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib41","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1751-7176.2010.00387.x","article-title":"Drug therapy for resistant hypertension: a simplified, mechanistic approach","volume":"12","author":"Mann","year":"2011","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"10.1016\/j.jash.2014.06.005_bib42","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1751-7176.2012.00605.x","article-title":"A simplified mechanistic algorithm for treating resistant hypertension: efficacy in a retrospective study","volume":"14","author":"Mann","year":"2012","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"10.1016\/j.jash.2014.06.005_bib43","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1001\/archinte.1991.00400090078014","article-title":"Resistant hypertension in a tertiary care clinic","volume":"151","author":"Yakovlevitch","year":"1991","journal-title":"Arch Intern Med"},{"issue":"5 Pt 1","key":"10.1016\/j.jash.2014.06.005_bib44","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.amjhyper.2004.11.021","article-title":"Resistant hypertension revisited: a comparison of two university-based cohorts","volume":"18","author":"Garg","year":"2005","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib45","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/jch.12105","article-title":"Patient and physician adherence in hypertension management","volume":"15","author":"Turner","year":"2013","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"10.1016\/j.jash.2014.06.005_bib46","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2174\/157340310791162695","article-title":"Physiologic tailoring of treatment in resistant hypertension","volume":"6","author":"Spence","year":"2010","journal-title":"Curr Cardiol Rev"},{"key":"10.1016\/j.jash.2014.06.005_bib47","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/jch.12090","article-title":"Rationale for establishing a mechanism to increase reimbursement to hypertension specialist","volume":"15","author":"Elliott","year":"2013","journal-title":"J Clin Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib48","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1159\/000358603","article-title":"Chlorthalidone for poorly controlled hypertension in chronic kidney disease: an interventional pilot study","volume":"39","author":"Agarwal","year":"2014","journal-title":"Am J Nephrol"},{"key":"10.1016\/j.jash.2014.06.005_bib49","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.ahj.2004.12.005","article-title":"Effects of eplerenone versus losartan in patients with\u00a0low-renin hypertension","volume":"150","author":"Weinberger","year":"2005","journal-title":"Am Heart J"},{"key":"10.1016\/j.jash.2014.06.005_bib50","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1161\/HYPERTENSIONAHA.109.140988","article-title":"Efficacy of spironolactone therapy in patients with true resistant hypertension","volume":"55","author":"de Souza","year":"2010","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib51","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1345\/aph.1R011","article-title":"Safety of mineralocorticoid receptor antagonists in patients receiving hemodialysis","volume":"46","author":"Baker","year":"2012","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.jash.2014.06.005_bib52","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1097\/HJH.0b013e3283455ca5","article-title":"A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism","volume":"29","author":"Parthasarathy","year":"2011","journal-title":"J\u00a0Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib53","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/MBP.0b013e32833c7308","article-title":"Administration-time-dependent effects of blood pressure-lowering medications: basis for the chronotherapy of hypertension","volume":"15","author":"Smolensky","year":"2010","journal-title":"Blood Press Monit"},{"key":"10.1016\/j.jash.2014.06.005_bib54","doi-asserted-by":"crossref","first-page":"209","DOI":"10.2165\/11206770-000000000-00000","article-title":"Olmesartan medoxomil\/amlodipine\/hydrochlorothiazide: fixed-dose combination in hypertension","volume":"71","author":"Deeks","year":"2011","journal-title":"Drugs"},{"key":"10.1016\/j.jash.2014.06.005_bib55","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.amjmed.2012.01.003","article-title":"Financial reinforcers for improving medication adherence: findings from a meta-analysis","volume":"125","author":"Petry","year":"2012","journal-title":"Am J Med"},{"key":"10.1016\/j.jash.2014.06.005_bib56","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1161\/HYPERTENSIONAHA.113.00687","article-title":"Measuring, analyzing, and managing drug adherence in resistant hypertension","volume":"62","author":"Burnier","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib57","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.jash.2013.07.006","article-title":"Perception of uncontrolled blood pressure and non-adherence to anti-hypertensive agents in diabetic hypertensive patients","volume":"7","author":"Ledur","year":"2013","journal-title":"J Am Soc Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib58","series-title":"Encyclopedia of Behavioral Medicine","first-page":"33","article-title":"Adherence","author":"Howren","year":"2013"},{"key":"10.1016\/j.jash.2014.06.005_bib59","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1136\/heartjnl-2013-305063","article-title":"High rates of non-adherence to antihypertensive treatment revealed by high-performance liquid chromatography-tandem mass spectrometry (HP LC-MS\/MS) urine analysis","volume":"100","author":"Tomaszewski","year":"2014","journal-title":"Heart"},{"key":"10.1016\/j.jash.2014.06.005_bib60","first-page":"CD000011","article-title":"Interventions for enhancing medication adherence","author":"Haynes","year":"2008","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jash.2014.06.005_bib61","doi-asserted-by":"crossref","first-page":"785","DOI":"10.7326\/0003-4819-157-11-201212040-00538","article-title":"Interventions to improve adherence to self-administered medications for chronic diseases in the United States: a systematic review","volume":"157","author":"Viswanathan","year":"2012","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jash.2014.06.005_bib62","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/hr.2010.183","article-title":"Difficult-to-control arterial hypertension or uncooperative patients? The assessment of serum antihypertensive drug levels to differentiate non-responsiveness from non-adherence to recommended therapy","volume":"34","author":"Ceral","year":"2011","journal-title":"Hypertens Res"},{"key":"10.1016\/j.jash.2014.06.005_bib63","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1097\/HJH.0b013e32835e2286","article-title":"Resistant hypertension? Assessment of adherence by toxicological urine analysis","volume":"31","author":"Jung","year":"2013","journal-title":"J Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib64","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1161\/HYPERTENSIONAHA.113.01452","article-title":"Renal sympathetic denervation in patients with treatment-resistant hypertension after witnessed intake of medication before qualifying ambulatory blood pressure","volume":"62","author":"Fadl Elmula","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib65","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1093\/eurheartj\/ehs041","article-title":"The human sympathetic nervous system: its relevance in hypertension and heart failure","volume":"33","author":"Parati","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jash.2014.06.005_bib66","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/MNH.0b013e32834db45d","article-title":"Sympathetic nervous system: role in hypertension and in chronic kidney disease","volume":"21","author":"Grassi","year":"2012","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib67","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/B978-0-444-53491-0.00026-2","article-title":"The central sympathetic nervous system in hypertension","volume":"117","author":"Mancia","year":"2013","journal-title":"Handb Clin Neurol"},{"key":"10.1016\/j.jash.2014.06.005_bib68","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1001\/jama.1949.02900420012004","article-title":"Effect of sympathectomy on blood pressure in hypertension: a review of 13 years\u2019 experience of the Massachusetts General Hospital","volume":"140","author":"Evelyn","year":"1949","journal-title":"JAMA"},{"key":"10.1016\/j.jash.2014.06.005_bib69","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1001\/jama.1956.02960470019005","article-title":"Hypertension and associated cardiovascular disease; comparison of male and female mortality rates and their influence on selection of therapy","volume":"160","author":"Smithwick","year":"1956","journal-title":"JAMA"},{"key":"10.1016\/j.jash.2014.06.005_bib70","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1097\/00000658-194111440-00018","article-title":"Total thoracic and partial to total lumbar sympathectomy and celiac ganglionectomy in the treatment of hypertension","volume":"114","author":"Grimson","year":"1941","journal-title":"Ann Surg"},{"key":"10.1016\/j.jash.2014.06.005_bib71","first-page":"65","article-title":"Surgery in hypertension","volume":"2","author":"Smithwick","year":"1948","journal-title":"Lancet"},{"key":"10.1016\/j.jash.2014.06.005_bib72","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1097\/00000658-194906000-00012","article-title":"Results of treatment of patients with hypertension by total thoracic and partial to total lumbar sympathectomy, splanchnicectomy and celiac ganglionectomy","volume":"129","author":"Grimson","year":"1949","journal-title":"Ann Surg"},{"key":"10.1016\/j.jash.2014.06.005_bib73","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1007\/s11886-010-0156-z","article-title":"Premise, promise, and potential limitations of invasive devices to treat hypertension","volume":"13","author":"Martin","year":"2011","journal-title":"Curr Cardiol Rep"},{"key":"10.1016\/j.jash.2014.06.005_bib74","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s11906-009-0087-5","article-title":"Carotid baroreflex activation: past, present, and future","volume":"12","author":"Scheffers","year":"2010","journal-title":"Curr Hypertens Rep"},{"key":"10.1016\/j.jash.2014.06.005_bib75","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.jacc.2011.06.008","article-title":"Baroreflex activation therapy lowers blood pressure in patients with resistant hypertension: results from the double-blind, randomized, placebo-controlled rheos pivotal trial","volume":"58","author":"Bisognano","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jash.2014.06.005_bib76","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1016\/j.jacc.2010.11.048","article-title":"Improved cardiac structure and function with chronic treatment using an implantable device in resistant hypertension: results from European and United States trials of the Rheos system","volume":"57","author":"Bisognano","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jash.2014.06.005_bib77","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jash.2012.01.003","article-title":"Baroreflex activation therapy provides durable benefit in patients with resistant hypertension: results of long-term follow-up in the Rheos Pivotal Trial","volume":"6","author":"Bakris","year":"2012","journal-title":"J Am Soc Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib78","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.jash.2012.04.004","article-title":"Minimally invasive system for baroreflex activation therapy chronically lowers blood pressure with pacemaker-like safety profile: results from the Barostim neo trial","volume":"6","author":"Hoppe","year":"2012","journal-title":"J Am Soc Hypertens"},{"key":"10.1016\/j.jash.2014.06.005_bib79","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/S0140-6736(09)60566-3","article-title":"Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study","volume":"373","author":"Krum","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.jash.2014.06.005_bib80","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1161\/HYPERTENSIONAHA.110.163014","article-title":"Catheter-based renal sympathetic denervation for resistant hypertension: durability of blood pressure reduction out to 24 months","volume":"57","year":"2011","journal-title":"Hypertension"},{"key":"10.1016\/j.jash.2014.06.005_bib81","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1016\/S0140-6736(10)62039-9","article-title":"Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial","volume":"376","author":"Esler","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.jash.2014.06.005_bib82","doi-asserted-by":"crossref","first-page":"2132","DOI":"10.1093\/eurheartj\/eht197","article-title":"Safety and efficacy of a multi-electrode renal sympathetic denervation system in resistant hypertension: the EnligHTN I trial","volume":"34","author":"Worthley","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jash.2014.06.005_bib83","unstructured":"REDUCE-HTN trial (annual meeting of Transcatheter Cardiovascular Therapeutics (TCT) (TCT, San Francisco, October\u00a02013."},{"key":"10.1016\/j.jash.2014.06.005_bib84","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1016\/j.jacc.2013.06.023","article-title":"Renal denervation in moderate treatment resistant hypertension","volume":"62","author":"Ott","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jash.2014.06.005_bib85","doi-asserted-by":"crossref","first-page":"484","DOI":"10.4244\/EIJV9I4A78","article-title":"Rationale and design of a large registry on renal denervation: the Global SYMPLICITY registry","volume":"9","author":"B\u00f6hm","year":"2013","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jash.2014.06.005_bib86","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1093\/eurheartj\/eht141","article-title":"Vascular lesions induced by renal nerve ablation as assessed by optical coherence tomography: pre- and post-procedural comparison with the Simplicity catheter\u00a0system and the EnligHTN multi-electrode renal denervation catheter","volume":"34","author":"Templin","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jash.2014.06.005_bib87","unstructured":"Dawood O, Gertner M, Brinton T. Ultrasonic renal denervation in severe hypertension (annual meeting of the Cardiovascular Research Technology (CRT), Washington, D.C. February 25,\u00a02014."}],"container-title":["Journal of the American Society of Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933171114006330?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933171114006330?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T13:31:38Z","timestamp":1761831098000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1933171114006330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":87,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["S1933171114006330"],"URL":"https:\/\/doi.org\/10.1016\/j.jash.2014.06.005","relation":{},"ISSN":["1933-1711"],"issn-type":[{"type":"print","value":"1933-1711"}],"subject":[],"published":{"date-parts":[[2014,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Detection, evaluation, and treatment of severe and resistant hypertension","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Society of Hypertension","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jash.2014.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}