{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T22:01:30Z","timestamp":1775167290656,"version":"3.50.1"},"reference-count":11,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","ashjournal.com","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the American Society of Hypertension"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.jash.2017.01.012","type":"journal-article","created":{"date-parts":[[2017,2,3]],"date-time":"2017-02-03T16:17:39Z","timestamp":1486138659000},"page":"136-139","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["The importance of genetic counseling and genetic screening: a case report of a 16-year-old boy with resistant hypertension and severe hypokalemia"],"prefix":"10.1016","volume":"11","author":[{"given":"Ze-Min","family":"Kuang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia-Jie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing-Hua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen-Qiu","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1506-7385","authenticated-orcid":false,"given":"Long","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jash.2017.01.012_bib1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ijcard.2007.01.119","article-title":"Secondary hypertension: current diagnosis and treatment","volume":"124","author":"Chiong","year":"2008","journal-title":"Int J Cardiol"},{"issue":"11","key":"10.1016\/j.jash.2017.01.012_bib2","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1007\/s00467-008-0744-y","article-title":"The bottom of the differential diagnosis list: unusual causes of pediatric hypertension","volume":"24","author":"Grinsell","year":"2009","journal-title":"Pediatr Nephrol"},{"issue":"5","key":"10.1016\/j.jash.2017.01.012_bib3","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1210\/jc.2015-4061","article-title":"The management of primary aldosteronism: case detection, diagnosis, and treatment: an Endocrine Society Clinical Practice Guideline","volume":"101","author":"Funder","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"issue":"8","key":"10.1016\/j.jash.2017.01.012_bib4","first-page":"1401","article-title":"Genetic diagnosis of Liddle's syndrome by mutation analysis of SCNN1B and SCNN1G in a Chinese family","volume":"125","author":"Wang","year":"2012","journal-title":"Chin Med J (Engl)"},{"issue":"8","key":"10.1016\/j.jash.2017.01.012_bib5","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1097\/00004872-199816080-00008","article-title":"Genetic analysis of the epithelial sodium channel in Liddle's syndrome","volume":"16","author":"Uehara","year":"1998","journal-title":"J Hypertens"},{"issue":"2","key":"10.1016\/j.jash.2017.01.012_bib6","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.gene.2015.12.061","article-title":"Epithelial sodium channel (ENaC) family: phylogeny, structure-function, tissue distribution, and associated inherited diseases","volume":"579","author":"Hanukoglu","year":"2016","journal-title":"Gene"},{"issue":"11","key":"10.1016\/j.jash.2017.01.012_bib7","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1111\/jch.12598","article-title":"Prevalence of Liddle syndrome among young hypertension patients of undetermined cause in a Chinese population","volume":"17","author":"Wang","year":"2015","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"10.1016\/j.jash.2017.01.012_bib8","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/367463a0","article-title":"Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits","volume":"367","author":"Canessa","year":"1994","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.jash.2017.01.012_bib9","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/nrneph.2013.275","article-title":"Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells","volume":"10","author":"Warnock","year":"2014","journal-title":"Nat Rev Nephrol"},{"issue":"8","key":"10.1016\/j.jash.2017.01.012_bib10","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1038\/ajh.2011.76","article-title":"A clinical phenotype mimicking essential hypertension in a newly discovered family with Liddle\u2019s syndrome","volume":"24","author":"Rossi","year":"2011","journal-title":"Am J Hypertens"},{"issue":"25","key":"10.1016\/j.jash.2017.01.012_bib11","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.cca.2014.05.015","article-title":"Molecular genetics of Liddle's syndrome","volume":"436","author":"Yang","year":"2014","journal-title":"Clin Chim Acta"}],"container-title":["Journal of the American Society of Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933171117300372?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1933171117300372?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T13:45:43Z","timestamp":1549287943000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1933171117300372"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["S1933171117300372"],"URL":"https:\/\/doi.org\/10.1016\/j.jash.2017.01.012","relation":{},"ISSN":["1933-1711"],"issn-type":[{"value":"1933-1711","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The importance of genetic counseling and genetic screening: a case report of a 16-year-old boy with resistant hypertension and severe hypokalemia","name":"articletitle","label":"Article Title"},{"value":"Journal of the American Society of Hypertension","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jash.2017.01.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 American Society of Hypertension. All rights reserved.","name":"copyright","label":"Copyright"}]}}