{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T07:48:12Z","timestamp":1785916092296,"version":"3.56.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Autoimmunity"],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1016\/j.jaut.2008.04.023","type":"journal-article","created":{"date-parts":[[2008,6,10]],"date-time":"2008-06-10T04:33:36Z","timestamp":1213072416000},"page":"136-141","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"title":["PDIA3, HSPA5 and vimentin, proteins identified by 2-DE in the valvular tissue, are the target antigens of peripheral and heart infiltrating T cells from chronic rheumatic heart disease patients"],"prefix":"10.1016","volume":"31","author":[{"given":"Kellen C.","family":"Fa\u00e9","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Diefenbach da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelina M.B.","family":"Bilate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana C.","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo M.A.","family":"Pomerantzeff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Helena","family":"Kiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clovis A.A.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edecio","family":"Cunha-Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Kalil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiza","family":"Guilherme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaut.2008.04.023_bib1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1056\/NEJM200101183440308","article-title":"Acute pharyngitis","volume":"344","author":"Bisno","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaut.2008.04.023_bib2","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1128\/CMR.13.3.470","article-title":"Pathogenesis of group A streptococcal infections","volume":"13","author":"Cunningham","year":"2000","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.jaut.2008.04.023_bib3","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1161\/01.CIR.92.3.415","article-title":"Human heart-infiltrating T cell clones from rheumatic heart disease patients recognize both streptococcal and cardiac proteins","volume":"92","author":"Guilherme","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.jaut.2008.04.023_bib4","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1172\/JCI7132","article-title":"Cytotoxicity mAb from rheumatic carditis recognizes heart valves and laminin","volume":"106","author":"Galvin","year":"2000","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jaut.2008.04.023_bib5","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1086\/318076","article-title":"Pathogenic mechanisms in rheumatic carditis: focus on valvular endothelium","volume":"183","author":"Roberts","year":"2001","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jaut.2008.04.023_bib6","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/0002-9343(83)91124-5","article-title":"Tissue distribution of lymphocytes in rheumatic heart valves as defined by monoclonal anti-T cell antibodies","volume":"74","author":"Raizada","year":"1983","journal-title":"Am J Med"},{"key":"10.1016\/j.jaut.2008.04.023_bib7","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0090-1229(89)90174-8","article-title":"Identification of mononuclear cells and T cell subsets in rheumatic valvulitis","volume":"52","author":"Kemeny","year":"1989","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1016\/j.jaut.2008.04.023_bib8","doi-asserted-by":"crossref","first-page":"5448","DOI":"10.4049\/jimmunol.175.8.5448","article-title":"T cell mimicry and epitope specificity of cross-reactive T cell clones from rheumatic heart disease","volume":"175","author":"Ellis","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.jaut.2008.04.023_bib9","doi-asserted-by":"crossref","first-page":"5662","DOI":"10.4049\/jimmunol.176.9.5662","article-title":"Mimicry in recognition of cardiac myosin peptides by heart-intralesional T cell clones from rheumatic heart disease","volume":"176","author":"Fae","year":"2006","journal-title":"J Immunol"},{"key":"10.1016\/j.jaut.2008.04.023_bib10","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/S0002-9440(10)63415-3","article-title":"Rheumatic heart disease: proinflammatory cytokines play a role in the progression and maintenance of valvular lesions","volume":"165","author":"Guilherme","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jaut.2008.04.023_bib11","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1126\/science.2578225","article-title":"Myosin: a link between streptococci and heart","volume":"227","author":"Krisher","year":"1985","journal-title":"Science"},{"key":"10.1016\/j.jaut.2008.04.023_bib12","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.4049\/jimmunol.143.8.2677","article-title":"Human and murine antibodies cross-reactive with streptococcal M protein and myosin recognize the sequence GLN-LYS-SER-LYS-GLN in M protein","volume":"143","author":"Cunningham","year":"1989","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.jaut.2008.04.023_bib13","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.4049\/jimmunol.151.7.3902","article-title":"A subset of mouse monoclonal antibodies cross-reactive with cytoskeletal proteins and group A streptococcal M proteins recognizes N-acetyl-beta-d-glucosamine","volume":"151","author":"Shikhman","year":"1993","journal-title":"J Immunol"},{"key":"10.1016\/j.jaut.2008.04.023_bib14","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1161\/01.CIR.89.2.916","article-title":"Guidelines for long-term management of patients with Kawasaki disease. Report from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association","volume":"89","author":"Dajani","year":"1994","journal-title":"Circulation"},{"key":"10.1016\/j.jaut.2008.04.023_bib15","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.yexcr.2003.11.029","article-title":"Changes in protein expression in p53 deleted spontaneous thymic lymphomas","volume":"295","author":"Honore","year":"2004","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.jaut.2008.04.023_bib16","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/0022-1759(87)90429-7","article-title":"A simple new method for using antigens separated by polyacrylamide gel electrophoresis to stimulate lymphocytes \u201cin vitro\u201d after converting bands cut from Western blots into antigen-bearing particles","volume":"98","author":"Abou-Zeid","year":"1987","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.jaut.2008.04.023_bib17","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1084\/jem.164.4.998","article-title":"Polyspecificity of antistreptococcal murine monoclonal antibodies and their implications in autoimmunity","volume":"164","author":"Cunningham","year":"1986","journal-title":"J Exp Med"},{"key":"10.1016\/j.jaut.2008.04.023_bib18","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.4049\/jimmunol.146.9.3132","article-title":"Epitopes of group A streptococcal M protein shared with antigens of articular cartilage and synovium","volume":"146","author":"Baird","year":"1991","journal-title":"J Immunol"},{"key":"10.1016\/j.jaut.2008.04.023_bib19","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1038\/ni1485","article-title":"Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer","volume":"8","author":"Wearsch","year":"2007","journal-title":"Nat Immunol"},{"key":"10.1016\/j.jaut.2008.04.023_bib20","doi-asserted-by":"crossref","DOI":"10.1186\/ar2085","article-title":"Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach","volume":"8","author":"Matsuo","year":"2006","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.jaut.2008.04.023_bib21","doi-asserted-by":"crossref","first-page":"30873","DOI":"10.1074\/jbc.272.49.30873","article-title":"BiP, a major chaperone protein of the endoplasmic reticulum lumen, plays a direct and important role in the storage of the rapidly exchanging pool of Ca2+","volume":"272","author":"Lievremont","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jaut.2008.04.023_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1615\/CritRevEukarGeneExpr.v4.i1.10","article-title":"The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications","volume":"4","author":"Little","year":"1994","journal-title":"Crit Rev Eukaryot Gene Expr"},{"key":"10.1016\/j.jaut.2008.04.023_bib23","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1016\/S0021-9258(17)42090-4","article-title":"A set of endoplasmic reticulum proteins possessing properties of molecular chaperones includes Ca(2+)-binding proteins and members of the thioredoxin superfamily","volume":"269","author":"Nigam","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jaut.2008.04.023_bib24","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1006\/exnr.1998.7002","article-title":"The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis","volume":"155","author":"Yu","year":"1999","journal-title":"Exp Neurol"},{"key":"10.1016\/j.jaut.2008.04.023_bib25","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1046\/j.1365-2249.2000.01283.x","article-title":"Autoantibodies in the sera of patients with rheumatic heart disease: characterization of myocardial antigens by two-dimensional immunoblotting and N-terminal sequence analysis","volume":"121","author":"Tontsch","year":"2000","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jaut.2008.04.023_bib26","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/art.21550","article-title":"Production of a novel class of polyreactive pathogenic autoantibodies in BXD2 mice causes glomerulonephritis and arthritis","volume":"54","author":"Hsu","year":"2006","journal-title":"Arthritis Rheum"}],"container-title":["Journal of Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841108000681?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841108000681?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T07:59:13Z","timestamp":1760255953000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896841108000681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["S0896841108000681"],"URL":"https:\/\/doi.org\/10.1016\/j.jaut.2008.04.023","relation":{},"ISSN":["0896-8411"],"issn-type":[{"value":"0896-8411","type":"print"}],"subject":[],"published":{"date-parts":[[2008,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PDIA3, HSPA5 and vimentin, proteins identified by 2-DE in the valvular tissue, are the target antigens of peripheral and heart infiltrating T cells from chronic rheumatic heart disease patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Autoimmunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaut.2008.04.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}