{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T01:38:45Z","timestamp":1789609125690,"version":"build-2803163510"},"reference-count":44,"publisher":"Elsevier BV","issue":"3-4","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Autoimmunity"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1016\/j.jaut.2009.02.008","type":"journal-article","created":{"date-parts":[[2009,3,27]],"date-time":"2009-03-27T06:01:51Z","timestamp":1238133711000},"page":"240-245","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":317,"title":["Catastrophic antiphospholipid syndrome (CAPS): Descriptive analysis of a series of 280 patients from the \u201cCAPS Registry\u201d"],"prefix":"10.1016","volume":"32","author":[{"given":"Ricard","family":"Cervera","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Bucciarelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A.","family":"Plas\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 A.","family":"G\u00f3mez-Puerta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Plaza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Pons-Estel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yehuda","family":"Shoenfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Ingelmo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"Espinos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaut.2009.02.008_bib1","first-page":"508","article-title":"The catastrophic antiphospholipid antibody syndrome","volume":"19","author":"Asherson","year":"1992","journal-title":"J Rheumatol"},{"key":"10.1016\/j.jaut.2009.02.008_bib2","first-page":"95","article-title":"The catastrophic antiphospholipid syndrome \u2013 Asherson's syndrome","volume":"154","author":"Piette","year":"2003","journal-title":"Ann Med Intern"},{"key":"10.1016\/j.jaut.2009.02.008_bib3","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/00005792-199805000-00005","article-title":"Catastrophic antibody syndrome. Clinical and laboratory features of 50 patients","volume":"77","author":"Asherson","year":"1998","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.jaut.2009.02.008_bib4","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/00005792-200111000-00002","article-title":"Catastrophic antiphospholipid syndrome: clues to the pathogenesis from a series of 80 patients","volume":"80","author":"Asherson","year":"2001","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.jaut.2009.02.008_bib5","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1002\/art.10187","article-title":"Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1000 patients","volume":"46","author":"Cervera","year":"2002","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jaut.2009.02.008_bib6","doi-asserted-by":"crossref","first-page":"2568","DOI":"10.1002\/art.22018","article-title":"Mortality in the catastrophic antiphospholipid syndrome: causes of death and prognostic factors in a series of 250 patients","volume":"54","author":"Bucciarelli","year":"2006","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jaut.2009.02.008_bib7","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.autrev.2006.01.001","article-title":"V Meeting of the European Forum on Antiphospholipid Antibodies","volume":"5","author":"Cervera","year":"2006","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jaut.2009.02.008_bib8","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1136\/ard.2006.061671","article-title":"Catastrophic antiphospholipid syndrome during pregnancy and puerperium: maternal and fetal characteristics of 15 cases","volume":"66","author":"G\u00f3mez-Puerta","year":"2007","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jaut.2009.02.008_bib9","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1136\/ard.2004.026377","article-title":"Disseminated intravascular coagulation in catastrophic antiphospholipid syndrome: clinical and haematological characteristics of 23 patients","volume":"64","author":"Asherson","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jaut.2009.02.008_bib10","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1136\/ard.62.6.530","article-title":"Long term outcome of catastrophic antiphospholipid syndrome survivors","volume":"62","author":"Erkan","year":"2003","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jaut.2009.02.008_bib11","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1136\/ard.2005.037671","volume":"65","year":"2006","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jaut.2009.02.008_bib12","first-page":"346","article-title":"The clinical spectrum of catastrophic antiphospholipid syndrome in the absence and presence of lupus","volume":"34","author":"Bayraktar","year":"2007","journal-title":"J Rheumatol"},{"key":"10.1016\/j.jaut.2009.02.008_bib13","doi-asserted-by":"crossref","first-page":"3320","DOI":"10.1002\/art.11359","article-title":"Catastrophic antiphospholipid syndrome. Where do we stand?","volume":"48","author":"Erkan","year":"2003","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jaut.2009.02.008_bib14","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1191\/0961203303lu394oa","article-title":"Catastrophic antiphospholipid syndrome: international consensus statement on classification criteria and treatment guidelines","volume":"12","author":"Asherson","year":"2003","journal-title":"Lupus"},{"key":"10.1016\/j.jaut.2009.02.008_bib15","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1136\/ard.2004.025759","article-title":"Validation of the preliminary criteria for the classification of catastrophic antiphospholipid syndrome","volume":"64","author":"Cervera","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jaut.2009.02.008_bib16","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1056\/NEJM199908193410807","article-title":"Disseminated intravascular coagulation","volume":"341","author":"Levi","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jaut.2009.02.008_bib17","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1136\/ard.2003.007245","article-title":"Thrombotic microangiopathic haemolytic anaemia and antiphospholipid antibodies","volume":"63","author":"Espinosa","year":"2004","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jaut.2009.02.008_bib18","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0165-2478(99)00004-8","article-title":"Molecular mimicry between host and pathogen: examples from parasites and implication","volume":"67","author":"Abu Shakra","year":"1999","journal-title":"Immunol Lett"},{"key":"10.1016\/j.jaut.2009.02.008_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/vim.1995.8.1","article-title":"The viral autoimmunity relationship","volume":"8","author":"Cohen","year":"1995","journal-title":"Viral Immunol"},{"key":"10.1016\/j.jaut.2009.02.008_bib20","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1006\/jaut.1996.0029","article-title":"Common infections, idiotypic dysregulation, autoantibody spread and induction of autoimmune diseases","volume":"9","author":"Shoenfeld","year":"1996","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jaut.2009.02.008_bib21","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1177\/096120339400300615","article-title":"Anticardiolipin antibodies in infections are heterogeneous in their dependency on (2-glycoprotein I): analysis of anticardiolipin antibodies in leprosy","volume":"3","author":"Hojnik","year":"1994","journal-title":"Lupus"},{"key":"10.1016\/j.jaut.2009.02.008_bib22","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1136\/ard.2003.014175","article-title":"Antiphospholipid syndrome associated with infections: clinical and microbiological characteristics of 100 patients","volume":"63","author":"Cervera","year":"2004","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jaut.2009.02.008_bib23","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0049-3848(99)00059-6","article-title":"Different types of antiphospholipid antibodies in AIDS: a comparison with syphilis and the antiphospholipid syndrome","volume":"95","author":"De Larra\u00f1aga","year":"1999","journal-title":"Thromb Res"},{"key":"10.1016\/j.jaut.2009.02.008_bib24","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1002\/(SICI)1098-2825(1999)13:2<59::AID-JCLA3>3.0.CO;2-Q","article-title":"Antiphosphatidylserine antibodies in patients with autoimmune diseases and HIV-infected patients: effects of Tween 20 and relationship with antibodies to beta2-glycoprotein I","volume":"13","author":"Gonz\u00e1lez","year":"1999","journal-title":"J Clin Lab Anal"},{"key":"10.1016\/j.jaut.2009.02.008_bib25","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1006\/jaut.1999.0324","article-title":"Antiphospholipid antibodies in HIV infection and SLE with or without anti-phospholipid syndrome; comparisons of phospholipid specificity, avidity and reactivity with beta2-GPI","volume":"13","author":"Petrovas","year":"1999","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jaut.2009.02.008_bib26","doi-asserted-by":"crossref","first-page":"5185","DOI":"10.1182\/blood.V87.12.5185.bloodjournal87125185","article-title":"Antiphosphatidylserine antibodies in human immunodeficiency virus-1 patients with evidence of T-cell apoptosis and mediate antibody-dependence cellular cytotoxicity","volume":"87","author":"Silvestris","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.jaut.2009.02.008_bib27","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1093\/clinids\/24.2.197","article-title":"Antiphospholipid syndrome associated with cytomegalovirus infection: case report and review","volume":"24","author":"Labarca","year":"1997","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jaut.2009.02.008_bib28","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1191\/096120399678841034","article-title":"Hughes syndrome associated with cytomegalovirus infection","volume":"8","author":"Uthman","year":"1999","journal-title":"Lupus"},{"key":"10.1016\/j.jaut.2009.02.008_bib29","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1006\/jaut.2000.0403","article-title":"New developments in viral peptides and APL induction","volume":"15","author":"Gharavi","year":"2000","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jaut.2009.02.008_bib30","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1177\/096120339900800607","article-title":"Induction of antiphospholipid antibodies by immunization with viral peptides","volume":"8","author":"Gharavi","year":"1999","journal-title":"Lupus"},{"key":"10.1016\/j.jaut.2009.02.008_bib31","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1136\/ard.2005.045443","article-title":"Infectious origin of the antiphospholipid syndrome","volume":"65","author":"Shoenfeld","year":"2006","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jaut.2009.02.008_bib32","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1023\/B:JOCI.0000018058.28764.ce","article-title":"Antiphospholipid syndrome infectious origin","volume":"24","author":"Blank","year":"2004","journal-title":"J Clin Immunol"},{"key":"10.1016\/j.jaut.2009.02.008_bib33","doi-asserted-by":"crossref","first-page":"5751","DOI":"10.4049\/jimmunol.158.12.5751","article-title":"Stress and autoimmunity: the neuropeptides corticotropin-releasing and urocortin suppress encephalomyelitis via effects on both the hypothalamic-pituitary-adrenal axis and the immune system","volume":"158","author":"Poliak","year":"1997","journal-title":"J Immunol"},{"key":"10.1016\/j.jaut.2009.02.008_bib34","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1006\/jaut.2000.0397","article-title":"Tissue factor pathway and the antiphospholipid syndrome","volume":"15","author":"Roubey","year":"2000","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jaut.2009.02.008_bib35","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1002\/art.23109","article-title":"A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies","volume":"57","author":"Ruiz-Irastorza","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jaut.2009.02.008_bib36","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.autrev.2008.08.001","article-title":"Predictive, protective, orphan autoantibodies: the example of anti-phospholipid antibodies","volume":"7","author":"Meroni","year":"2008","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jaut.2009.02.008_bib37","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.autrev.2007.10.001","article-title":"Antiphospholipid antibodies, antiphospholipid syndrome and infections","volume":"7","author":"Sene","year":"2008","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jaut.2009.02.008_bib38","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.jaut.2007.11.014","article-title":"Pathogenesis of the antiphospholipid syndrome: an additional example of the mosaic of autoimmunity","volume":"30","author":"Meroni","year":"2008","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jaut.2009.02.008_bib39","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jaut.2007.11.004","volume":"30","author":"Andreoli","year":"2008","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jaut.2009.02.008_bib40","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.autrev.2007.11.017","article-title":"Hughes syndrome (the antiphospholipid syndrome): ten clinical lessons","volume":"7","author":"Hughes","year":"2008","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jaut.2009.02.008_bib41","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.autrev.2007.11.009","article-title":"Microvascular and microangiopathic antiphospholipid-associated syndromes (\u201cMAPS\u201d): semantic or antisemantic?","volume":"7","author":"Asherson","year":"2008","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jaut.2009.02.008_bib42","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jaut.2007.11.011","article-title":"Autoantibody explosion in antiphospholipid syndrome","volume":"30","author":"Shoenfeld","year":"2008","journal-title":"J Autoimmun"},{"key":"10.1016\/j.jaut.2009.02.008_bib43","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.autrev.2007.06.003","article-title":"OxLDL\/beta2GPI-anti-oxLDL\/beta2GPI complex and atherosclerosis in SLE patients","volume":"7","author":"Bassi","year":"2007","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jaut.2009.02.008_bib44","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.autrev.2007.06.002","article-title":"Insights into atherosclerosis therapy in antiphospholipid syndrome","volume":"7","author":"Belizna","year":"2007","journal-title":"Autoimmun Rev"}],"container-title":["Journal of Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841109000353?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841109000353?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T08:00:42Z","timestamp":1760256042000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896841109000353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":44,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["S0896841109000353"],"URL":"https:\/\/doi.org\/10.1016\/j.jaut.2009.02.008","relation":{},"ISSN":["0896-8411"],"issn-type":[{"value":"0896-8411","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Catastrophic antiphospholipid syndrome (CAPS): Descriptive analysis of a series of 280 patients from the \u201cCAPS Registry\u201d","name":"articletitle","label":"Article Title"},{"value":"Journal of Autoimmunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaut.2009.02.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}