{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T08:11:33Z","timestamp":1793175093620,"version":"4.5.0"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Autoimmunity"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1016\/j.jaut.2013.01.013","type":"journal-article","created":{"date-parts":[[2013,3,13]],"date-time":"2013-03-13T15:45:18Z","timestamp":1363189518000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":127,"special_numbering":"C","title":["PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis"],"prefix":"10.1016","volume":"43","author":[{"given":"H. Benjamin","family":"Larman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uri","family":"Laserson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Querol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrijn","family":"Verhaeghen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole L.","family":"Solimini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George Jing","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul L.","family":"Klarenbeek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George M.","family":"Church","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Hafler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert M.","family":"Plenge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Nigrovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip L.","family":"De Jager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilse","family":"Weets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geert A.","family":"Martens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin C.","family":"O'Connor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Elledge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaut.2013.01.013_bib1","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/nbt.1856","article-title":"Autoantigen discovery with a synthetic human peptidome","volume":"29","author":"Larman","year":"2011","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.jaut.2013.01.013_bib2","unstructured":"HB Larman, M Salajegheh, R Nazareno, T Lam, J Sauld, H Steen, et\u00a0al. Cytosolic 5\u2032-nucleotidase 1a autoimmunity in sporadic inclusion body myositis, annals of neurology, in press."},{"key":"10.1016\/j.jaut.2013.01.013_bib3","doi-asserted-by":"crossref","first-page":"e1000024","DOI":"10.1371\/journal.pgen.1000024","article-title":"Defining the role of the MHC in autoimmunity: a review and pooled analysis","volume":"4","author":"Fernando","year":"2008","journal-title":"PLoS Genet"},{"key":"10.1016\/j.jaut.2013.01.013_bib4","first-page":"48","article-title":"Prediction and prevention of type 1 diabetes mellitus","volume":"3","author":"Zhang","year":"2011","journal-title":"J\u00a0Diabetes"},{"key":"10.1016\/j.jaut.2013.01.013_bib5","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/j.1750-3639.2004.tb00049.x","article-title":"Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis","volume":"14","author":"Serafini","year":"2004","journal-title":"Brain Pathol"},{"key":"10.1016\/j.jaut.2013.01.013_bib6","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jneuroim.2006.07.006","article-title":"Oligoclonal bands in multiple sclerosis cerebrospinal fluid: an update on methodology and clinical usefulness","volume":"180","author":"Link","year":"2006","journal-title":"J\u00a0Neuroimmunol"},{"key":"10.1016\/j.jaut.2013.01.013_bib7","doi-asserted-by":"crossref","first-page":"2572","DOI":"10.1056\/NEJMoa032534","article-title":"Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis","volume":"350","author":"Edwards","year":"2004","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jaut.2013.01.013_bib8","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/art.23721","article-title":"American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis","volume":"59","author":"Saag","year":"2008","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jaut.2013.01.013_bib9","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1056\/NEJMoa0904452","article-title":"Rituximab, B-lymphocyte depletion, and preservation of beta-cell function","volume":"361","author":"Pescovitz","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jaut.2013.01.013_bib10","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1056\/NEJMoa0706383","article-title":"B-cell depletion with rituximab in relapsing-remitting multiple sclerosis","volume":"358","author":"Hauser","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jaut.2013.01.013_bib11","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s00125-009-1618-y","volume":"53","author":"De Grijse","year":"2010","journal-title":"Diabetologia"},{"key":"10.1016\/j.jaut.2013.01.013_bib12","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.2337\/dc10-2268","article-title":"Contribution of antibodies against IA-2beta and zinc transporter 8 to classification of diabetes diagnosed under 40 years of age","volume":"34","author":"Vermeulen","year":"2011","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jaut.2013.01.013_bib13","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.2337\/db08-0522","article-title":"A\u00a0common nonsynonymous single nucleotide polymorphism in the SLC30A8 gene determines ZnT8 autoantibody specificity in type 1 diabetes","volume":"57","author":"Wenzlau","year":"2008","journal-title":"Diabetes"},{"key":"10.1016\/j.jaut.2013.01.013_bib14","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/nm1488","article-title":"Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein","volume":"13","author":"O'connor","year":"2007","journal-title":"Nat Med"},{"key":"10.1016\/j.jaut.2013.01.013_bib15","doi-asserted-by":"crossref","DOI":"10.1101\/pdb.prot5448","article-title":"Illumina sequencing library preparation for highly multiplexed target capture and sequencing","volume":"2010","author":"Meyer","year":"2010","journal-title":"Cold Spring Harbor Protoc"},{"key":"10.1016\/j.jaut.2013.01.013_bib16","doi-asserted-by":"crossref","first-page":"5116","DOI":"10.1073\/pnas.091062498","article-title":"Significance analysis of microarrays applied to the ionizing radiation response","volume":"98","author":"Tusher","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jaut.2013.01.013_bib17","series-title":"An introduction to the bootstrap","author":"Efron","year":"1993"},{"key":"10.1016\/j.jaut.2013.01.013_bib18","first-page":"28","article-title":"Fitting a mixture model by expectation maximization to discover motifs in biopolymers","volume":"2","author":"Bailey","year":"1994","journal-title":"Proc Int Conf Intell Syst Mol Biol"},{"key":"10.1016\/j.jaut.2013.01.013_bib19","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1172\/JCI200523661","article-title":"Identification of Epstein\u2013Barr virus proteins as putative targets of the immune response in multiple sclerosis","volume":"115","author":"Cepok","year":"2005","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.jaut.2013.01.013_bib20","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1126\/science.1103492","article-title":"The human polyomavirus, JCV, uses serotonin receptors to infect cells","volume":"306","author":"Elphick","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.jaut.2013.01.013_bib21","doi-asserted-by":"crossref","first-page":"11063","DOI":"10.1073\/pnas.93.20.11063","article-title":"Identification of peptides specific for cerebrospinal fluid antibodies in multiple sclerosis by using phage libraries","volume":"93","author":"Cortese","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jaut.2013.01.013_bib22","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1136\/jnnp.65.1.48","article-title":"Molecular approach to find target(s) for oligoclonal bands in multiple sclerosis","volume":"65","author":"Rand","year":"1998","journal-title":"J\u00a0Neurol Neurosurg Psychiatr"},{"key":"10.1016\/j.jaut.2013.01.013_bib23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJMoa1110740","article-title":"Potassium channel KIR4.1 as an immune target in multiple sclerosis","volume":"367","author":"Srivastava","year":"2012","journal-title":"N\u00a0Engl J Med"}],"container-title":["Journal of Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089684111300019X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089684111300019X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T08:07:04Z","timestamp":1760256424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S089684111300019X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":23,"alternative-id":["S089684111300019X"],"URL":"https:\/\/doi.org\/10.1016\/j.jaut.2013.01.013","relation":{},"ISSN":["0896-8411"],"issn-type":[{"value":"0896-8411","type":"print"}],"subject":[],"published":{"date-parts":[[2013,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis","name":"articletitle","label":"Article Title"},{"value":"Journal of Autoimmunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaut.2013.01.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}