{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T10:51:33Z","timestamp":1787655093241,"version":"build-2736575974"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"OPUS","award":["2012\/07\/B\/NZ5\/02506"],"award-info":[{"award-number":["2012\/07\/B\/NZ5\/02506"]}]},{"name":"Faculty of Biochemistry, Biophysics and Biotechnology of Jagiellonian University"},{"name":"National Research Center"},{"DOI":"10.13039\/501100004569","name":"Ministry of Science and Higher Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004569","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Autoimmunity"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.jaut.2018.07.012","type":"journal-article","created":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T09:21:41Z","timestamp":1532337701000},"page":"56-69","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"special_numbering":"C","title":["Molecular profiling of regulatory T cells in pulmonary sarcoidosis"],"prefix":"10.1016","volume":"94","author":[{"given":"Neli","family":"Kachamakova-Trojanowska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Jazwa-Kusior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Szade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukasz","family":"Kasper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerzy","family":"Soja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Andrychiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogdan","family":"Jakiela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Plutecka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Sanak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicja","family":"Jozkowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Sladek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jozef","family":"Dulak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaut.2018.07.012_bib1","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.bbrc.2011.12.068","article-title":"Differential expression of microRNA and predicted targets in pulmonary sarcoidosis","volume":"417","author":"Crouser","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jaut.2018.07.012_bib2","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s00005-014-0315-9","article-title":"Differential inflammatory microRNA and cytokine expression in pulmonary sarcoidosis","volume":"63","author":"Jazwa","year":"2015","journal-title":"Arch. Immunol. Ther. Exp. (Warsz.)"},{"key":"10.1016\/j.jaut.2018.07.012_bib3","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12881-016-0266-6","article-title":"Altered miRNA expression in pulmonary sarcoidosis","volume":"17","author":"Kisza\u0142kiewicz","year":"2016","journal-title":"BMC Med. Genet."},{"key":"10.1016\/j.jaut.2018.07.012_bib4","doi-asserted-by":"crossref","first-page":"7853","DOI":"10.1073\/pnas.1121072109","article-title":"Common patterns and disease-related signatures in tuberculosis and sarcoidosis","volume":"109","author":"Maertzdorf","year":"2012","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.jaut.2018.07.012_bib5","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01124-2017","article-title":"Increased T-helper 17.1 cells in sarcoidosis mediastinal lymph nodes","volume":"51","author":"Broos","year":"2018","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.jaut.2018.07.012_bib6","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jaut.2017.12.012","article-title":"Th17-lineage cells in pulmonary sarcoidosis and L\u00f6fgren's syndrome: friend or foe?","volume":"87","author":"Miedema","year":"2018","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.jaut.2018.07.012_bib7","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1084\/jem.20050648","article-title":"The immune paradox of sarcoidosis and regulatory T cells","volume":"203","author":"Miyara","year":"2006","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jaut.2018.07.012_bib8","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1097\/MCP.0000000000000303","article-title":"T-cell immunology in sarcoidosis: disruption of a delicate balance between helper and regulatory T-cells","volume":"22","author":"Broos","year":"2016","journal-title":"Curr. Opin. Pulm. Med."},{"key":"10.1016\/j.jaut.2018.07.012_bib9","doi-asserted-by":"crossref","DOI":"10.1186\/s41038-015-0001-0","article-title":"Pathological conditions re-shape physiological Tregs into pathological Tregs","volume":"3","author":"Yang","year":"2015","journal-title":"Burns Trauma"},{"key":"10.1016\/j.jaut.2018.07.012_bib10","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1038\/nri3494","article-title":"MicroRNA-mediated regulation of T helper cell differentiation and plasticity","volume":"13","author":"Baumjohann","year":"2013","journal-title":"Nat. Rev. Immunol."},{"issue":"190","key":"10.1016\/j.jaut.2018.07.012_bib11","first-page":"5446","article-title":"Reversal of global CD4+ subset dysfunction is associated with spontaneous clinical resolution of pulmonary sarcoidosis","volume":"1950","author":"Oswald-Richter","year":"2013","journal-title":"J. Immunol. Baltim. Md."},{"key":"10.1016\/j.jaut.2018.07.012_bib12","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s12931-015-0265-8","article-title":"Impaired survival of regulatory T cells in pulmonary sarcoidosis","volume":"16","author":"Broos","year":"2015","journal-title":"Respir. Res."},{"key":"10.1016\/j.jaut.2018.07.012_bib13","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1034\/j.1399-3003.1999.14d02.x","article-title":"ATS\/ers\/wasog statement on sarcoidosis. Sarcoidosis statement committee. American thoracic society. European respiratory society. World association for sarcoidosis and other granulomatous disorders","volume":"14","author":"Costabel","year":"1999","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.jaut.2018.07.012_bib14","doi-asserted-by":"crossref","first-page":"374","DOI":"10.2144\/03342mt01","article-title":"TM4: a free, open-source system for microarray data management and analysis","volume":"34","author":"Saeed","year":"2003","journal-title":"BioTechniques"},{"key":"10.1016\/j.jaut.2018.07.012_bib15","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/nprot.2014.006","article-title":"Full-length RNA-seq from single cells using Smart-seq2","volume":"9","author":"Picelli","year":"2014","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.jaut.2018.07.012_bib16","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.jaut.2018.07.012_bib17","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1038\/nprot.2013.092","article-title":"Large-scale gene function analysis with the PANTHER classification system","volume":"8","author":"Mi","year":"2013","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.jaut.2018.07.012_bib18","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/nprot.2006.83","article-title":"The single-step method of RNA isolation by acid guanidinium thiocyanate\u2013phenol\u2013chloroform extraction: twenty-something years on","volume":"1","author":"Chomczynski","year":"2006","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.jaut.2018.07.012_bib19","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.virol.2003.11.005","article-title":"Interferon-inducible MyD88 protein inhibits hepatitis B virus replication","volume":"319","author":"Xiong","year":"2004","journal-title":"Virology"},{"key":"10.1016\/j.jaut.2018.07.012_bib20","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1183\/09031936.00028209","article-title":"Multiplex immune serum biomarker profiling in sarcoidosis and systemic sclerosis","volume":"34","author":"Beirne","year":"2009","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.jaut.2018.07.012_bib21","first-page":"102","article-title":"Soluble interleukin-2 receptor in blood from patients with sarcoidosis and idiopathic pulmonary fibrosis","volume":"11","author":"Tsutsumi","year":"1994","journal-title":"Sarcoidosis"},{"key":"10.1016\/j.jaut.2018.07.012_bib22","doi-asserted-by":"crossref","first-page":"W460","DOI":"10.1093\/nar\/gkv403","article-title":"DIANA-miRPath v3.0: deciphering microRNA function with experimental support","volume":"43","author":"Vlachos","year":"2015","journal-title":"Nucleic Acids Res."},{"issue":"177","key":"10.1016\/j.jaut.2018.07.012_bib23","first-page":"2186","article-title":"Defective activation of protein kinase C and Ras-ERK pathways limits IL-2 production and proliferation by CD4+CD25+ regulatory T cells","volume":"1950","author":"Hickman","year":"2006","journal-title":"J. Immunol. Baltim. Md."},{"key":"10.1016\/j.jaut.2018.07.012_bib24","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1111\/cei.12138","article-title":"Disordered Toll-like receptor 2 responses in the pathogenesis of pulmonary sarcoidosis","volume":"173","author":"Gabrilovich","year":"2013","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.jaut.2018.07.012_bib25","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.it.2013.01.004","article-title":"Regulation of NF-\u03baB in autoimmunity","volume":"34","author":"Sun","year":"2013","journal-title":"Trends Immunol."},{"key":"10.1016\/j.jaut.2018.07.012_bib26","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1172\/JCI25439","article-title":"Toll-like receptor 2 controls expansion and function of regulatory T cells","volume":"116","author":"Sutmuller","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jaut.2018.07.012_bib27","doi-asserted-by":"crossref","first-page":"3325","DOI":"10.1093\/emboj\/19.13.3325","article-title":"The apoptotic signaling pathway activated by Toll-like receptor-2","volume":"19","author":"Aliprantis","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/j.jaut.2018.07.012_bib28","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.intimp.2009.01.027","article-title":"Regulatory T cells and Toll-like receptors: what is the missing link?","volume":"9","author":"Dai","year":"2009","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jaut.2018.07.012_bib29","doi-asserted-by":"crossref","first-page":"26","DOI":"10.25100\/cm.v46i1.1570","article-title":"Microarray analysis of the in vitro granulomatous response to Mycobacterium tuberculosis H37Ra","volume":"46","author":"Reyes","year":"2015","journal-title":"Colomb. Med. Cali Colomb."},{"issue":"Suppl 3","key":"10.1016\/j.jaut.2018.07.012_bib30","article-title":"Regulatory T cells and toll-like receptors: regulating the regulators","volume":"66","author":"Sutmuller","year":"2007","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2018.07.012_bib31","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/nri3605","article-title":"Homeostatic control of regulatory T cell diversity","volume":"14","author":"Liston","year":"2014","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jaut.2018.07.012_bib32","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1038\/ni.2649","article-title":"Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells","volume":"14","author":"Pierson","year":"2013","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jaut.2018.07.012_bib33","doi-asserted-by":"crossref","first-page":"4237","DOI":"10.1038\/s41598-017-04109-6","article-title":"Identification of Jak-STAT signaling involvement in sarcoidosis severity via a novel microRNA-regulated peripheral blood mononuclear cell gene signature","volume":"7","author":"Zhou","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jaut.2018.07.012_bib34","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1038\/icb.2014.51","article-title":"STAT1 plays a role in TLR signal transduction and inflammatory responses","volume":"92","author":"Luu","year":"2014","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.jaut.2018.07.012_bib35","doi-asserted-by":"crossref","first-page":"945169","DOI":"10.1155\/2014\/945169","article-title":"MicroRNAs: new regulators of Toll-like receptor signalling pathways","volume":"2014","author":"He","year":"2014","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.jaut.2018.07.012_bib36","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/nri2708","article-title":"Physiological and pathological roles for microRNAs in the immune system","volume":"10","author":"O'Connell","year":"2010","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jaut.2018.07.012_bib37","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1128\/MCB.01206-10","article-title":"Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival","volume":"31","author":"Beier","year":"2011","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.jaut.2018.07.012_bib38","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1016\/j.cellsig.2013.06.007","article-title":"Antagonistic crosstalk between NF-\u03baB and SIRT1 in the regulation of inflammation and metabolic disorders","volume":"25","author":"Kauppinen","year":"2013","journal-title":"Cell. Signal."},{"key":"10.1016\/j.jaut.2018.07.012_bib39","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1038\/sj.emboj.7600244","article-title":"Modulation of NF-\u03baB-dependent transcription and cell survival by the SIRT1 deacetylase","volume":"23","author":"Yeung","year":"2004","journal-title":"EMBO J."},{"key":"10.1016\/j.jaut.2018.07.012_bib40","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1038\/icb.2011.102","article-title":"Sirtuin 1 in immune regulation and autoimmunity","volume":"90","author":"Kong","year":"2012","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.jaut.2018.07.012_bib41","doi-asserted-by":"crossref","DOI":"10.1186\/s12974-016-0712-6","article-title":"miR-124a and miR-155 enhance differentiation of regulatory T cells in patients with neuropathic pain","volume":"13","author":"Heyn","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.jaut.2018.07.012_bib42","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1471-2199-13-4","article-title":"Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells","volume":"13","author":"Li","year":"2012","journal-title":"BMC Mol. Biol."},{"key":"10.1016\/j.jaut.2018.07.012_bib43","doi-asserted-by":"crossref","first-page":"13421","DOI":"10.1073\/pnas.0801613105","article-title":"miR-34a repression of SIRT1 regulates apoptosis","volume":"105","author":"Yamakuchi","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A"}],"container-title":["Journal of Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841118302373?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841118302373?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T08:20:42Z","timestamp":1760257242000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896841118302373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":43,"alternative-id":["S0896841118302373"],"URL":"https:\/\/doi.org\/10.1016\/j.jaut.2018.07.012","relation":{},"ISSN":["0896-8411"],"issn-type":[{"value":"0896-8411","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular profiling of regulatory T cells in pulmonary sarcoidosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Autoimmunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaut.2018.07.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}