{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T13:08:39Z","timestamp":1789650519188,"version":"4.0.0"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Autoimmunity"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.jaut.2018.09.004","type":"journal-article","created":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T19:22:00Z","timestamp":1537212120000},"page":"134-141","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"special_numbering":"C","title":["Increased ischemic stroke, acute coronary artery disease and mortality in patients with granulomatosis with polyangiitis and microscopic polyangiitis"],"prefix":"10.1016","volume":"96","author":[{"given":"M.","family":"Mourguet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Chauveau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Faguer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.B.","family":"Ruidavets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"B\u00e9jot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Ribes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Huart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Alric","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Balardy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Astudillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Adoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Sailler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Pugnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaut.2018.09.004_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/art.37715","article-title":"2012 revised international Chapel Hill consensus conference nomenclature of vasculitides","volume":"65","author":"Jennette","year":"2013","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2018.09.004_bib2","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1056\/NEJMoa0909905","article-title":"Rituximab versus cyclophosphamide for ANCA-associated vasculitis","volume":"363","author":"Stone","year":"2010","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jaut.2018.09.004_bib3","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1056\/NEJMoa1404231","article-title":"Rituximab versus azathioprine for maintenance in ANCA-associated vasculitis","volume":"371","author":"Guillevin","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jaut.2018.09.004_bib4","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1136\/ard.2007.071936","article-title":"Outcomes from studies of antineutrophil cytoplasm antibody associated vasculitis: a systematic review by the European League against Rheumatism systemic vasculitis task force","volume":"67","author":"Mukhtyar","year":"2008","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2018.09.004_bib5","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1002\/art.21117","article-title":"Damage caused by Wegener's granulomatosis and its treatment: prospective data from the Wegener's Granulomatosis Etanercept Trial (WGET)","volume":"52","author":"Seo","year":"2005","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2018.09.004_bib6","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.amjmed.2008.06.010","article-title":"Subclinical atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus","volume":"121","author":"Salmon","year":"2008","journal-title":"Am. J. Med."},{"key":"10.1016\/j.jaut.2018.09.004_bib7","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1161\/ATVBAHA.114.303567","article-title":"IL-17 and Th17 cells in atherosclerosis: subtle and contextual roles","volume":"35","author":"Taleb","year":"2015","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.jaut.2018.09.004_bib8","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1023\/B:THRO.0000037664.77460.d8","article-title":"Evidence for C-reactive protein's role in (CRP) vascular disease: atherothrombosis, immuno-regulation and CRP","volume":"17","author":"Mazer","year":"2004","journal-title":"J. Thromb. Thrombolysis"},{"key":"10.1016\/j.jaut.2018.09.004_bib9","first-page":"96","article-title":"Increased prevalence of subclinical atherosclerosis in patients with small-vessel vasculitis","volume":"93","author":"Chironi","year":"2007","journal-title":"Heart Br. Card Soc."},{"key":"10.1016\/j.jaut.2018.09.004_bib10","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1136\/ard.2004.029033","article-title":"Accelerated atherosclerosis in patients with Wegener's granulomatosis","volume":"64","author":"de Leeuw","year":"2005","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2018.09.004_bib11","doi-asserted-by":"crossref","first-page":"723","DOI":"10.3899\/jrheum.130882","article-title":"Factors associated with major cardiovascular events in patients with systemic necrotizing vasculitides: results of a longterm followup study","volume":"41","author":"Terrier","year":"2014","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.jaut.2018.09.004_bib12","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1196\/annals.1381.002","article-title":"Atherosclerosis in ANCA-associated vasculitides","volume":"1107","author":"Pagnoux","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.jaut.2018.09.004_bib13","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1002\/1529-0131(200112)44:12<2737::AID-ART460>3.0.CO;2-#","article-title":"High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors","volume":"44","author":"del Rinc\u00f3n","year":"2001","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2018.09.004_bib14","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1161\/01.CIR.0000054612.26458.B2","article-title":"Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis","volume":"107","author":"Solomon","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jaut.2018.09.004_bib15","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1093\/oxfordjournals.aje.a009122","article-title":"Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study","volume":"145","author":"Manzi","year":"1997","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.jaut.2018.09.004_bib16","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1002\/1529-0131(199902)42:2<338::AID-ANR17>3.0.CO;2-U","article-title":"Premature morbidity from cardiovascular and cerebrovascular diseases in women with systemic lupus erythematosus","volume":"42","author":"Ward","year":"1999","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2018.09.004_bib17","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1002\/art.24386","article-title":"Increased morbidity from ischemic heart disease in patients with Wegener's granulomatosis","volume":"60","author":"Faurschou","year":"2009","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2018.09.004_bib18","doi-asserted-by":"crossref","first-page":"3493","DOI":"10.1002\/art.24957","article-title":"Increased incidence of cardiovascular events in patients with antineutrophil cytoplasmic antibody-associated vasculitides: a matched-pair cohort study","volume":"60","author":"Morgan","year":"2009","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2018.09.004_bib19","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1002\/acr.20433","article-title":"A model to predict cardiovascular events in patients with newly diagnosed Wegener's granulomatosis and microscopic polyangiitis","volume":"63","author":"Suppiah","year":"2011","journal-title":"Arthritis Care Res."},{"key":"10.1016\/j.jaut.2018.09.004_bib20","doi-asserted-by":"crossref","first-page":"2752","DOI":"10.1002\/art.39762","article-title":"Risk of myocardial infarction and stroke in patients with granulomatosis with polyangiitis (Wegener's): a population-based study","volume":"68","author":"Avi\u00f1a-Zubieta","year":"2016","journal-title":"Arthr. Rheumatol. Hoboken NJ"},{"key":"10.1016\/j.jaut.2018.09.004_bib21","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.ijcard.2015.06.087","article-title":"Prevalence and prognostic relevance of cardiac involvement in ANCA-associated vasculitis: eosinophilic granulomatosis with polyangiitis and granulomatosis with polyangiitis","volume":"199","author":"Hazebroek","year":"2015","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.jaut.2018.09.004_bib22","first-page":"671","article-title":"Birmingham vasculitis activity score (BVAS) in systemic necrotizing vasculitis","volume":"87","author":"Luqmani","year":"1994","journal-title":"QJM Mon J. Assoc. Phys."},{"key":"10.1016\/j.jaut.2018.09.004_bib23","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1093\/eurheartj\/ehs184","article-title":"Third universal definition of myocardial infarction","volume":"33","author":"Thygesen","year":"2012","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.jaut.2018.09.004_bib24","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1161\/CIR.0b013e31828b82aa","article-title":"Management of patients with peripheral artery disease (compilation of 2005 and 2011 ACCF\/AHA guideline recommendations): a report of the American college of cardiology foundation\/American heart association task force on Practice guidelines","volume":"127","author":"Anderson","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.jaut.2018.09.004_bib25","first-page":"171","article-title":"Incidence, recurrence, and case fatality rates for myocardial infarction in southwestern France, 1985 to 1993","volume":"84","author":"Marques-Vidal","year":"2000","journal-title":"Heart Br. Card Soc."},{"key":"10.1016\/j.jaut.2018.09.004_bib26","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1177\/2047487312452967","article-title":"Gender- and age-specific trends in coronary heart disease mortality in France from 2000 to 2007: results from the MONICA registers","volume":"21","author":"Wagner","year":"2014","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.jaut.2018.09.004_bib27","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1136\/jnnp-2014-307614","article-title":"Stroke associated with giant cell arteritis: a population-based study","volume":"86","author":"Samson","year":"2015","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jaut.2018.09.004_bib28","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1080\/07853890.2016.1217035","article-title":"Impact of cardiovascular risk factor control on long-term cardiovascular and all-cause mortality in the general population","volume":"48","author":"B\u00e9rard","year":"2016","journal-title":"Ann. Med."},{"key":"10.1016\/j.jaut.2018.09.004_bib29","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/0140-6736(92)91277-F","article-title":"Wine, alcohol, platelets, and the French paradox for coronary heart disease","volume":"339","author":"Renaud","year":"1992","journal-title":"Lancet Lond. Engl."},{"key":"10.1016\/j.jaut.2018.09.004_bib30","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/MD.0b013e318205a4c6","article-title":"The Five-Factor Score revisited: assessment of prognoses of systemic necrotizing vasculitides based on the French Vasculitis Study Group (FVSG) cohort","volume":"90","author":"Guillevin","year":"2011","journal-title":"Medicine (Baltim.)"},{"key":"10.1016\/j.jaut.2018.09.004_bib31","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/art.20082","article-title":"Predicting mortality in systemic Wegener's granulomatosis: a survival analysis based on 93 patients","volume":"51","author":"Bligny","year":"2004","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2018.09.004_bib32","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/art.27763","article-title":"Improved outcome in 445 patients with Wegener's granulomatosis in a German vasculitis center over four decades","volume":"63","author":"Holle","year":"2011","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2018.09.004_bib33","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1093\/rheumatology\/kev286","article-title":"Clinical presentation and long-term outcome of 144 patients with microscopic polyangiitis in a monocentric German cohort","volume":"55","author":"Schirmer","year":"2016","journal-title":"Rheumatol. Oxf. Engl."},{"key":"10.1016\/j.jaut.2018.09.004_bib34","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1002\/acr.22423","article-title":"High risk of pulmonary embolism and deep venous thrombosis but not of stroke in granulomatosis with polyangiitis (Wegener's)","volume":"66","author":"Faurschou","year":"2014","journal-title":"Arthritis Care Res."},{"key":"10.1016\/j.jaut.2018.09.004_bib35","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1093\/rheumatology\/kex338","article-title":"Cardiovascular events in anti-neutrophil cytoplasmic antibody-associated vasculitis: a meta-analysis of observational studies","volume":"57","author":"Houben","year":"2018","journal-title":"Rheumatology"},{"key":"10.1016\/j.jaut.2018.09.004_bib36","first-page":"996","article-title":"Pathophysiology of ANCA-associated vasculitides","volume":"41","author":"Mouthon","year":"2012","journal-title":"Presse Med. Paris Fr 1983"},{"key":"10.1016\/j.jaut.2018.09.004_bib37","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1136\/ard.62.2.162","article-title":"Diffuse endothelial dysfunction is common to ANCA associated systemic vasculitis and polyarteritis nodosa","volume":"62","author":"Filer","year":"2003","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2018.09.004_bib38","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1016\/j.amjcard.2008.07.060","article-title":"The case for chronic kidney disease, diabetes mellitus, and myocardial infarction being equivalent risk factors for cardiovascular mortality in patients older than 65 years","volume":"102","author":"Rashidi","year":"2008","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.jaut.2018.09.004_bib39","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1136\/pgmj.70.830.863","article-title":"Corticosteroids: do they damage the cardiovascular system?","volume":"70","author":"Maxwell","year":"1994","journal-title":"Postgrad. Med. J."},{"key":"10.1016\/j.jaut.2018.09.004_bib40","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0163-7258(02)00297-8","article-title":"Mechanisms involved in the side effects of glucocorticoids","volume":"96","author":"Sch\u00e4cke","year":"2002","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.jaut.2018.09.004_bib41","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.cardiores.2004.07.006","article-title":"Does altered glucocorticoid homeostasis increase cardiovascular risk?","volume":"64","author":"Girod","year":"2004","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.jaut.2018.09.004_bib42","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1136\/hrt.2003.020180","article-title":"Use of oral glucocorticoids and risk of cardiovascular and cerebrovascular disease in a population based case-control study","volume":"90","author":"Souverein","year":"2004","journal-title":"Heart Br. Card Soc."},{"key":"10.1016\/j.jaut.2018.09.004_bib43","doi-asserted-by":"crossref","first-page":"764","DOI":"10.7326\/0003-4819-141-10-200411160-00007","article-title":"Taking glucocorticoids by prescription is associated with subsequent cardiovascular disease","volume":"141","author":"Wei","year":"2004","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.jaut.2018.09.004_bib44","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1093\/rheumatology\/41.5.572","article-title":"Predictors of survival and organ damage in Wegener's granulomatosis","volume":"41","author":"Koldingsnes","year":"2002","journal-title":"Rheumatol. Oxf. Engl."},{"key":"10.1016\/j.jaut.2018.09.004_bib45","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1002\/acr.22976","article-title":"Nationwide trends in hospitalizations and in-hospital mortality in granulomatosis with polyangiitis (Wegener's)","volume":"69","author":"Wallace","year":"2017","journal-title":"Arthritis Care Res."},{"key":"10.1016\/j.jaut.2018.09.004_bib46","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1093\/rheumatology\/kev390","article-title":"Impact of pre-existing co-morbidities on mortality in granulomatosis with polyangiitis: a cohort study","volume":"55","author":"Faurschou","year":"2016","journal-title":"Rheumatol. Oxf. Engl."},{"key":"10.1016\/j.jaut.2018.09.004_bib47","first-page":"589","article-title":"The incidence, prevalence and mortality of granulomatosis with polyangiitis in the UK Clinical Practice Research Datalink","volume":"56","author":"Pearce","year":"2017","journal-title":"Rheumatol. Oxf. Engl."},{"key":"10.1016\/j.jaut.2018.09.004_bib48","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1136\/ard.2010.137778","article-title":"Long-term patient survival in ANCA-associated vasculitis","volume":"70","author":"Flossmann","year":"2011","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2018.09.004_bib49","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1136\/ard.2009.109389","article-title":"Early mortality in systemic vasculitis: relative contribution of adverse events and active vasculitis","volume":"69","author":"Little","year":"2010","journal-title":"Ann. Rheum. Dis."}],"container-title":["Journal of Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841118304116?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841118304116?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T08:21:15Z","timestamp":1760257275000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896841118304116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":49,"alternative-id":["S0896841118304116"],"URL":"https:\/\/doi.org\/10.1016\/j.jaut.2018.09.004","relation":{},"ISSN":["0896-8411"],"issn-type":[{"value":"0896-8411","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased ischemic stroke, acute coronary artery disease and mortality in patients with granulomatosis with polyangiitis and microscopic polyangiitis","name":"articletitle","label":"Article Title"},{"value":"Journal of Autoimmunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaut.2018.09.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}