{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T02:02:41Z","timestamp":1792202561585,"version":"4.4.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Autoimmunity"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.jaut.2022.102795","type":"journal-article","created":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T04:11:47Z","timestamp":1643602307000},"page":"102795","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Gluten-free diet reduces autoimmune diabetes mellitus in mice across multiple generations in a microbiota-independent manner"],"prefix":"10.1016","volume":"127","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1860-385X","authenticated-orcid":false,"given":"Camilla H.F.","family":"Hansen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian S.","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Line F.","family":"Zachariassen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline M.J.","family":"Mentzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Laigaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukasz","family":"Krych","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis S.","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Gobbi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Haupt-Jorgensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karsten","family":"Buschard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel K.","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaut.2022.102795_bib1","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/(SICI)1520-7560(199909\/10)15:5<323::AID-DMRR53>3.0.CO;2-P","article-title":"Gluten-free diet prevents diabetes in NOD mice","volume":"15","author":"Funda","year":"1999","journal-title":"Diabetes Metab. Res. Rev."},{"key":"10.1016\/j.jaut.2022.102795_bib2","article-title":"Gluten-free diet modulates inflammation in salivary glands and pancreatic islets","author":"Haupt-Jorgensen","year":"2021","journal-title":"Oral Dis."},{"key":"10.1016\/j.jaut.2022.102795_bib3","doi-asserted-by":"crossref","first-page":"3047574","DOI":"10.1155\/2016\/3047574","article-title":"Gluten-free diet only during pregnancy efficiently prevents diabetes in NOD mouse offspring","volume":"2016","author":"Antvorskov","year":"2016","journal-title":"J. Diabetes Res."},{"key":"10.1016\/j.jaut.2022.102795_bib4","doi-asserted-by":"crossref","first-page":"2821","DOI":"10.2337\/db13-1612","article-title":"A maternal gluten-free diet reduces inflammation and diabetes incidence in the offspring of NOD mice","volume":"63","author":"Hansen","year":"2014","journal-title":"Diabetes"},{"key":"10.1016\/j.jaut.2022.102795_bib5","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1399-5448.2007.00311.x","article-title":"Maternal diet during pregnancy and islet autoimmunity in offspring","volume":"9","author":"Lamb","year":"2008","journal-title":"Pediatr. Diabetes"},{"key":"10.1016\/j.jaut.2022.102795_bib6","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1399-5448.2010.00668.x","article-title":"Maternal food consumption during pregnancy and risk of advanced beta-cell autoimmunity in the offspring","volume":"12","author":"Virtanen","year":"2011","journal-title":"Pediatr. Diabetes"},{"key":"10.1016\/j.jaut.2022.102795_bib7","doi-asserted-by":"crossref","first-page":"k3547","DOI":"10.1136\/bmj.k3547","article-title":"Association between maternal gluten intake and type 1 diabetes in offspring: national prospective cohort study in Denmark","volume":"362","author":"Antvorskov","year":"2018","journal-title":"BMJ"},{"key":"10.1016\/j.jaut.2022.102795_bib8","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1001\/jamapediatrics.2019.2564","article-title":"Association of cereal, gluten, and dietary fiber intake with islet autoimmunity and type 1 diabetes","volume":"173","author":"Hakola","year":"2019","journal-title":"JAMA Pediatr."},{"key":"10.1016\/j.jaut.2022.102795_bib9","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1111\/dom.13974","article-title":"Gluten-free diet in children with recent-onset type 1 diabetes: a 12-month intervention trial","volume":"22","author":"Neuman","year":"2020","journal-title":"Diabetes Obes. Metabol."},{"key":"10.1016\/j.jaut.2022.102795_bib10","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1136\/gutjnl-2017-314508","article-title":"Akkermansia muciniphila induces gut microbiota remodelling and controls islet autoimmunity in NOD mice","volume":"67","author":"Hanninen","year":"2018","journal-title":"Gut"},{"key":"10.1016\/j.jaut.2022.102795_bib11","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1007\/s00125-012-2564-7","article-title":"Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse","volume":"55","author":"Hansen","year":"2012","journal-title":"Diabetologia"},{"key":"10.1016\/j.jaut.2022.102795_bib12","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1053\/j.gastro.2016.06.041","article-title":"Duodenal bacteria from patients with celiac disease and healthy subjects distinctly affect gluten breakdown and immunogenicity","volume":"151","author":"Caminero","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jaut.2022.102795_bib13","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/nature18846","article-title":"Diet-microbiota interactions as moderators of human metabolism","volume":"535","author":"Sonnenburg","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.jaut.2022.102795_bib14","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.ebiom.2019.06.031","article-title":"Microbiome and type 1 diabetes","volume":"46","author":"Siljander","year":"2019","journal-title":"EBioMedicine"},{"key":"10.1016\/j.jaut.2022.102795_bib15","doi-asserted-by":"crossref","first-page":"701","DOI":"10.4049\/jimmunol.1502465","article-title":"Cutting edge: commensal microbiota has disparate effects on manifestations of polyglandular autoimmune inflammation","volume":"197","author":"Hansen","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2022.102795_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0078687","article-title":"Low incidence of spontaneous type 1 diabetes in non-obese diabetic mice raised on gluten-free diets is associated with changes in the intestinal microbiome","volume":"8","author":"Marietta","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jaut.2022.102795_bib17","doi-asserted-by":"crossref","first-page":"21204","DOI":"10.1038\/s41598-020-78404-0","article-title":"Dietary prebiotics promote intestinal Prevotella in association with a low-responding phenotype in a murine oxazolone-induced model of atopic dermatitis","volume":"10","author":"Laigaard","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jaut.2022.102795_bib18","doi-asserted-by":"crossref","first-page":"e2987","DOI":"10.1002\/dmrr.2987","article-title":"Gluten-free diet during pregnancy alleviates signs of diabetes and celiac disease in NOD mouse offspring","volume":"34","author":"Haupt-Jorgensen","year":"2018","journal-title":"Diabetes Metab. Res. Rev."},{"key":"10.1016\/j.jaut.2022.102795_bib19","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1007\/s00125-019-4910-5","article-title":"Targeting gut microbiota and barrier function with prebiotics to alleviate autoimmune manifestations in NOD mice","volume":"62","author":"Hansen","year":"2019","journal-title":"Diabetologia"},{"key":"10.1016\/j.jaut.2022.102795_bib20","doi-asserted-by":"crossref","first-page":"113285","DOI":"10.1016\/j.physbeh.2020.113285","article-title":"Effects of delivery mode on behavior in mouse offspring","volume":"230","author":"Zachariassen","year":"2021","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.jaut.2022.102795_bib21","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1038\/nmeth.2604","article-title":"UPARSE: highly accurate OTU sequences from microbial amplicon reads","volume":"10","author":"Edgar","year":"2013","journal-title":"Nat. Methods"},{"key":"10.1016\/j.jaut.2022.102795_bib22","series-title":"UNOISE2: Improved Error\u2010correction for Illumina 16S and ITS Amplicon Sequencing","author":"Edgar","year":"2016"},{"key":"10.1016\/j.jaut.2022.102795_bib23","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/s41587-019-0209-9","article-title":"Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2","volume":"37","author":"Bolyen","year":"2019","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.jaut.2022.102795_bib24","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/eji.201242462","article-title":"Gut microbiota regulates NKG2D ligand expression on intestinal epithelial cells","volume":"43","author":"Hansen","year":"2013","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jaut.2022.102795_bib25","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1177\/1753425915615195","article-title":"Oral antibiotics increase blood neutrophil maturation and reduce bacteremia and necrotizing enterocolitis in the immediate postnatal period of preterm pigs","volume":"22","author":"Nguyen","year":"2016","journal-title":"Innate Immun."},{"key":"10.1016\/j.jaut.2022.102795_bib26","doi-asserted-by":"crossref","first-page":"533","DOI":"10.3945\/jn.112.172361","article-title":"Dietary xylooligosaccharide downregulates IFN-\u03b3 and the low-grade inflammatory cytokine IL-1\u03b2 systemically in mice","volume":"143","author":"Hansen","year":"2013","journal-title":"J. Nutr."},{"key":"10.1016\/j.jaut.2022.102795_bib27","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.jaut.2022.102795_bib28","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1021\/acs.jproteome.8b00702","article-title":"Cytoscape StringApp: network analysis and visualization of proteomics data","volume":"18","author":"Doncheva","year":"2019","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.jaut.2022.102795_bib29","series-title":"Enrichment-visualizer","author":"Corsi","year":"2020"},{"key":"10.1016\/j.jaut.2022.102795_bib30","doi-asserted-by":"crossref","first-page":"D447","DOI":"10.1093\/nar\/gku1003","article-title":"STRING v10: protein-protein interaction networks, integrated over the tree of life","volume":"43","author":"Szklarczyk","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jaut.2022.102795_bib31","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0167-5699(93)90160-M","article-title":"NOD mouse colonies around the world--recent facts and figures","volume":"14","author":"Pozzilli","year":"1993","journal-title":"Immunol. Today"},{"key":"10.1016\/j.jaut.2022.102795_bib32","doi-asserted-by":"crossref","first-page":"11548","DOI":"10.1073\/pnas.1108924108","article-title":"Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice","volume":"108","author":"Kriegel","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jaut.2022.102795_bib33","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/dmrr.609","article-title":"Diabetes preventive gluten-free diet decreases the number of caecal bacteria in non-obese diabetic mice","volume":"22","author":"Hansen","year":"2006","journal-title":"Diabetes Metab. Res. Rev."},{"key":"10.1016\/j.jaut.2022.102795_bib34","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.cell.2005.05.007","article-title":"An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system","volume":"122","author":"Mazmanian","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.jaut.2022.102795_bib35","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1053\/j.gastro.2008.03.023","article-title":"Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3","volume":"135","author":"Lammers","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jaut.2022.102795_bib36","doi-asserted-by":"crossref","first-page":"12475","DOI":"10.1073\/pnas.0604317103","article-title":"Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes","volume":"103","author":"Chaparro","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jaut.2022.102795_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0066474","article-title":"Gliadin fragments and a specific gliadin 33-mer peptide close KATP channels and induce insulin secretion in INS-1E cells and rat islets of langerhans","volume":"8","author":"Dall","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jaut.2022.102795_bib38","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/(SICI)1099-0895(199612)12:4<341::AID-DMR173>3.0.CO;2-O","article-title":"Food-induced type 1 diabetes in the BB rat","volume":"12","author":"Scott","year":"1996","journal-title":"Diabetes Metab. Rev."},{"key":"10.1016\/j.jaut.2022.102795_bib39","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.3390\/nu10111746","article-title":"Possible prevention of diabetes with a gluten-free diet","volume":"10","author":"Haupt-Jorgensen","year":"2018","journal-title":"Nutrients"},{"key":"10.1016\/j.jaut.2022.102795_bib40","doi-asserted-by":"crossref","first-page":"12204","DOI":"10.1073\/pnas.0909122107","article-title":"Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota","volume":"107","author":"Round","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jaut.2022.102795_bib41","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/j.1365-2567.2010.03293.x","article-title":"Autoreactive natural killer T cells: promoting immune protection and immune tolerance through varied interactions with myeloid antigen-presenting cells","volume":"130","author":"Hegde","year":"2010","journal-title":"Immunology"},{"key":"10.1016\/j.jaut.2022.102795_bib42","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/nri1028","article-title":"Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity","volume":"3","author":"Wilson","year":"2003","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jaut.2022.102795_bib43","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/nri2904","article-title":"Presumed guilty: natural killer T cell defects and human disease","volume":"11","author":"Berzins","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jaut.2022.102795_bib44","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1189\/jlb.1106654","article-title":"Reduced CD4+ subset and Th1 bias of the human iNKT cells in Type 1 diabetes mellitus","volume":"81","author":"Kis","year":"2007","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.jaut.2022.102795_bib45","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.4049\/jimmunol.171.3.1266","article-title":"CD4+ NKT cells, but not conventional CD4+ T cells, are required to generate efferent CD8+ T regulatory cells following antigen inoculation in an immune-privileged site","volume":"171","author":"Nakamura","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2022.102795_bib46","doi-asserted-by":"crossref","first-page":"3138","DOI":"10.4049\/jimmunol.1101390","article-title":"CD4(+) type II NKT cells mediate ICOS and programmed death-1-dependent regulation of type 1 diabetes","volume":"188","author":"Kadri","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2022.102795_bib47","doi-asserted-by":"crossref","first-page":"499","DOI":"10.3390\/genes4030499","article-title":"Genes involved in type 1 diabetes: an update","volume":"4","author":"Bakay","year":"2013","journal-title":"Genes"},{"key":"10.1016\/j.jaut.2022.102795_bib48","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1080\/08820139.2019.1590395","article-title":"Association of CTLA-4 and CD28 gene polymorphisms with type 1 diabetes in south Indian population","volume":"48","author":"Gunavathy","year":"2019","journal-title":"Immunol. Invest."},{"key":"10.1016\/j.jaut.2022.102795_bib49","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/BF00271265","article-title":"TNF-alpha gene polymorphisms in type 1 (insulin-dependent) diabetes mellitus","volume":"32","author":"Badenhoop","year":"1989","journal-title":"Diabetologia"},{"key":"10.1016\/j.jaut.2022.102795_bib50","doi-asserted-by":"crossref","first-page":"14","DOI":"10.2337\/db11-1213","article-title":"Central role for interleukin-2 in type 1 diabetes","volume":"61","author":"Hulme","year":"2012","journal-title":"Diabetes"},{"key":"10.1016\/j.jaut.2022.102795_bib51","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.intimp.2019.02.018","article-title":"Interleukin-33 prevents the development of autoimmune diabetes in NOD mice","volume":"70","author":"Lu","year":"2019","journal-title":"Int. Immunopharm."},{"key":"10.1016\/j.jaut.2022.102795_bib52","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.4049\/jimmunol.1001036","article-title":"CD4+ CD25+ regulatory T cells prevent type 1 diabetes preceded by dendritic cell-dominant invasive insulitis by affecting chemotaxis and local invasiveness of dendritic cells","volume":"185","author":"Lee","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2022.102795_bib53","doi-asserted-by":"crossref","first-page":"894","DOI":"10.4049\/jimmunol.1700410","article-title":"On the role IL-4\/IL-13 heteroreceptor plays in regulation of type 1 diabetes","volume":"199","author":"Ukah","year":"2017","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2022.102795_bib54","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.4049\/jimmunol.173.3.1757","article-title":"Antigen presentation to celiac lesion-derived T cells of a 33-mer gliadin peptide naturally formed by gastrointestinal digestion","volume":"173","author":"Qiao","year":"2004","journal-title":"J. Immunol."}],"container-title":["Journal of Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841122000038?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841122000038?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T08:29:04Z","timestamp":1760257744000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896841122000038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":54,"alternative-id":["S0896841122000038"],"URL":"https:\/\/doi.org\/10.1016\/j.jaut.2022.102795","relation":{},"ISSN":["0896-8411"],"issn-type":[{"value":"0896-8411","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gluten-free diet reduces autoimmune diabetes mellitus in mice across multiple generations in a microbiota-independent manner","name":"articletitle","label":"Article Title"},{"value":"Journal of Autoimmunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaut.2022.102795","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102795"}}