{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T03:12:05Z","timestamp":1774494725965,"version":"3.50.1"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T00:00:00Z","timestamp":1660780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008368","name":"Gigtforeningen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008368","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Autoimmunity"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.jaut.2022.102884","type":"journal-article","created":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T07:07:35Z","timestamp":1661324855000},"page":"102884","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Left ventricular size and function in patients with systemic lupus erythematosus associate with lupus anticoagulant: An echocardiographic follow-up study"],"prefix":"10.1016","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0838-0987","authenticated-orcid":false,"given":"Katrine A.","family":"Myhr","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2880-1638","authenticated-orcid":false,"given":"Amanda H.","family":"Zinglersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9108-8604","authenticated-orcid":false,"given":"Marie-Louise F.","family":"Hermansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathies M.","family":"Jepsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7182-8954","authenticated-orcid":false,"given":"Katrine K.","family":"Iversen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3406-7209","authenticated-orcid":false,"given":"Anh T.","family":"Ngo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Redi","family":"Pecini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5654-4993","authenticated-orcid":false,"given":"S\u00f8ren","family":"Jacobsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaut.2022.102884_bib1","doi-asserted-by":"crossref","DOI":"10.1136\/lupus-2017-000221","article-title":"Associates and predictors of pleurisy or pericarditis in SLE","volume":"4","author":"Ryu","year":"2017","journal-title":"Lupus Sci. Med."},{"key":"10.1016\/j.jaut.2022.102884_bib2","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1093\/rheumatology\/kem371","article-title":"Associated factors and impact of myocarditis in patients with SLE from LUMINA, a multiethnic US cohort (LV). [corrected]","volume":"47","author":"Apte","year":"2008","journal-title":"Rheumatol. Oxf. Engl."},{"key":"10.1016\/j.jaut.2022.102884_bib3","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1161\/CIRCULATIONAHA.111.028522","article-title":"Increased risk for heart valve disease associated with antiphospholipid antibodies in patients with systemic lupus erythematosus: meta-analysis of echocardiographic studies","volume":"124","author":"Zuily","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.jaut.2022.102884_bib4","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1016\/j.jacc.2021.02.029","article-title":"Long-Term cardiovascular outcomes in systemic lupus erythematosus","volume":"77","author":"Yafasova","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.jaut.2022.102884_bib5","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1002\/acr.23018","article-title":"Risk of myocardial infarction and stroke in newly diagnosed systemic lupus erythematosus: a general population-based study","volume":"69","author":"Avi\u00f1a-Zubieta","year":"2017","journal-title":"Arthritis Care Res."},{"key":"10.1016\/j.jaut.2022.102884_bib6","first-page":"709","article-title":"The risk of cardiovascular morbidity and cardiovascular mortality in systemic lupus erythematosus and lupus nephritis: a Danish nationwide population-based cohort study","volume":"56","author":"Hermansen","year":"2017","journal-title":"Rheumatol. Oxf. Engl."},{"key":"10.1016\/j.jaut.2022.102884_bib7","first-page":"227","article-title":"Incidence and risk of heart failure in systemic lupus erythematosus","volume":"103","author":"Kim","year":"2017","journal-title":"Heart Br. Card. Soc."},{"key":"10.1016\/j.jaut.2022.102884_bib8","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1136\/annrheumdis-2016-210973","article-title":"Stroke in systemic lupus erythematosus: a Swedish population-based cohort study","volume":"76","author":"Arkema","year":"2017","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2022.102884_bib9","doi-asserted-by":"crossref","first-page":"R46","DOI":"10.1186\/ar3759","article-title":"Risk factors for cardiovascular mortality in patients with systemic lupus erythematosus, a prospective cohort study","volume":"14","author":"Gustafsson","year":"2012","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.jaut.2022.102884_bib10","doi-asserted-by":"crossref","first-page":"4238","DOI":"10.1093\/rheumatology\/keaa917","article-title":"Mortality in SLE patients compared with population controls in Finland in years 2000-2015","volume":"60","author":"Elfving","year":"2021","journal-title":"Rheumatol. Oxf. Engl."},{"key":"10.1016\/j.jaut.2022.102884_bib11","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3109\/08916934.2013.794793","article-title":"Evaluation of mortality, disease activity, treatment, clinical and immunological features of adult and late onset systemic Lupus erythematosus","volume":"46","author":"Cartella","year":"2013","journal-title":"Autoimmunity"},{"key":"10.1016\/j.jaut.2022.102884_bib12","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1080\/030097499442522","article-title":"Mortality and causes of death of 513 Danish patients with systemic lupus erythematosus","volume":"28","author":"Jacobsen","year":"1999","journal-title":"Scand. J. Rheumatol."},{"key":"10.1016\/j.jaut.2022.102884_bib13","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1177\/2047487314546826","article-title":"Predictors of cardiovascular events in patients with systemic lupus erythematosus (SLE): a systematic review and meta-analysis","volume":"22","author":"Ballocca","year":"2015","journal-title":"Eur. J. Prev. Cardiol."},{"key":"10.1016\/j.jaut.2022.102884_bib14","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1093\/aje\/kws130","article-title":"Incidence of and risk factors for adverse cardiovascular events among patients with systemic lupus erythematosus","volume":"176","author":"Magder","year":"2012","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.jaut.2022.102884_bib15","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1002\/art.1780251101","article-title":"The 1982 revised criteria for the classification of systemic lupus erythematosus","volume":"25","author":"Tan","year":"1982","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2022.102884_bib16","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1002\/art.1780400928","article-title":"Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus","volume":"40","author":"Hochberg","year":"1997","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2022.102884_bib17","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1093\/rheumatology\/key201","article-title":"Atherosclerosis and renal disease involvement in patients with systemic lupus erythematosus: a cross-sectional cohort study","volume":"57","author":"Hermansen","year":"2018","journal-title":"Rheumatol. Oxf. Engl."},{"key":"10.1016\/j.jaut.2022.102884_bib18","doi-asserted-by":"crossref","DOI":"10.1136\/lupus-2021-000507","article-title":"Characteristics of cardiovascular autonomic dysfunction and association with quality of life in patients with systemic lupus erythematosus","volume":"8","author":"Zinglersen","year":"2021","journal-title":"Lupus Sci. Med."},{"key":"10.1016\/j.jaut.2022.102884_bib19","first-page":"288","article-title":"Systemic lupus erythematosus disease activity index 2000","volume":"29","author":"Gladman","year":"2002","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.jaut.2022.102884_bib20","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/art.1780390303","article-title":"The development and initial validation of the Systemic Lupus International Collaborating Clinics\/American College of Rheumatology damage index for systemic lupus erythematosus","volume":"39","author":"Gladman","year":"1996","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2022.102884_bib21","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1002\/art.1780400928","article-title":"Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus","volume":"40","author":"Hochberg","year":"1997","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2022.102884_bib22","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1093\/ehjci\/jex244","volume":"18","author":"Galderisi","year":"2017","journal-title":"Eur. Heart J. Cardiovasc. Imaging."},{"key":"10.1016\/j.jaut.2022.102884_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2018.06.004","article-title":"Guidelines for performing a comprehensive transthoracic echocardiographic examination in adults: recommendations from the American society of echocardiography","volume":"32","author":"Mitchell","year":"2019","journal-title":"J. Am. Soc. Echocardiogr. Off. Publ. Am. Soc. Echocardiogr."},{"key":"10.1016\/j.jaut.2022.102884_bib24","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.echo.2016.01.011","article-title":"Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American society of echocardiography and the European association of cardiovascular imaging","volume":"29","author":"Nagueh","year":"2016","journal-title":"J. Am. Soc. Echocardiogr. Off. Publ. Am. Soc. Echocardiogr."},{"key":"10.1016\/j.jaut.2022.102884_bib25","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/ejhf.2161","article-title":"Change in ejection fraction and long-term mortality in adults referred for echocardiography","volume":"23","author":"Strange","year":"2021","journal-title":"Eur. J. Heart Fail."},{"key":"10.1016\/j.jaut.2022.102884_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2014.10.003","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"28","author":"Lang","year":"2015","journal-title":"J. Am. Soc. Echocardiogr. Off. Publ. Am. Soc. Echocardiogr."},{"key":"10.1016\/j.jaut.2022.102884_bib27","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1161\/01.CIR.0000036014.90197.FA","article-title":"Left ventricular remodeling after primary coronary angioplasty: patterns of left ventricular dilation and long-term prognostic implications","volume":"106","author":"Bolognese","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jaut.2022.102884_bib28","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1007\/s10067-016-3373-z","article-title":"Heart involvement in systemic lupus erythematosus: a systemic review and meta-analysis","volume":"35","author":"Chen","year":"2016","journal-title":"Clin. Rheumatol."},{"key":"10.1016\/j.jaut.2022.102884_bib29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s10238-019-00600-8","article-title":"Early echocardiographic detection of left ventricular diastolic dysfunction in patients with systemic lupus erythematosus asymptomatic for cardiovascular disease","volume":"20","author":"Leone","year":"2020","journal-title":"Clin. Exp. Med."},{"key":"10.1016\/j.jaut.2022.102884_bib30","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.semarthrit.2013.07.016","article-title":"Evolution of cardiac dysfunction in patients with antiphospholipid antibodies and\/or antiphospholipid syndrome: a 10-year follow-up study","volume":"43","author":"Kampolis","year":"2014","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.jaut.2022.102884_bib31","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/0002-8703(93)90123-Q","article-title":"The left ventricle in systemic lupus erythematosus: initial observations and a five-year follow-up in a university medical center population","volume":"125","author":"Winslow","year":"1993","journal-title":"Am. Heart J."},{"key":"10.1016\/j.jaut.2022.102884_bib32","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1136\/ard.2005.044073","article-title":"Cardiac dysfunction in patients with systemic lupus erythematosus and antiphospholipid syndrome","volume":"66","author":"Paran","year":"2007","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2022.102884_bib33","article-title":"Antiphospholipid syndrome","volume":"4","author":"Schreiber","year":"2018","journal-title":"Nat. Rev. Dis. Prim."},{"key":"10.1016\/j.jaut.2022.102884_bib34","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1002\/acr.22066","article-title":"Estimated frequency of antiphospholipid antibodies in patients with pregnancy morbidity, stroke, myocardial infarction, and deep vein thrombosis: a critical review of the literature","volume":"65","author":"Andreoli","year":"2013","journal-title":"Arthritis Care Res."},{"key":"10.1016\/j.jaut.2022.102884_bib35","doi-asserted-by":"crossref","DOI":"10.1136\/lupus-2020-000406","article-title":"Evaluation of different ways to identify persistent positivity of lupus anticoagulant in systemic lupus erythematosus","volume":"7","author":"Petri","year":"2020","journal-title":"Lupus Sci. Med."},{"key":"10.1016\/j.jaut.2022.102884_bib36","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1016\/S0140-6736(10)60709-X","article-title":"Antiphospholipid syndrome","volume":"376","author":"Ruiz-Irastorza","year":"2010","journal-title":"Lancet Lond. Engl."},{"key":"10.1016\/j.jaut.2022.102884_bib37","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1093\/rheumatology\/keg182","article-title":"Atherosclerosis in premenopausal women with antiphospholipid syndrome and systemic lupus erythematosus: a controlled study","volume":"42","author":"Vlachoyiannopoulos","year":"2003","journal-title":"Rheumatol. Oxf. Engl."},{"key":"10.1016\/j.jaut.2022.102884_bib38","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.120.018555","article-title":"Coronary microvascular dysfunction in systemic lupus erythematosus","volume":"10","author":"Weber","year":"2021","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.jaut.2022.102884_bib39","first-page":"27","article-title":"Myocardial ischemia in the absence of obstructive coronary artery disease in systemic lupus erythematosus., JACC Cardiovasc","volume":"4","author":"Ishimori","year":"2011","journal-title":"Imaging"},{"key":"10.1016\/j.jaut.2022.102884_bib40","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3109\/08916934.2013.856005","article-title":"Definitions of and contributions to cardiovascular disease in systemic lupus erythematosus","volume":"47","author":"Gustafsson","year":"2014","journal-title":"Autoimmunity"},{"key":"10.1016\/j.jaut.2022.102884_bib41","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1161\/CIRCIMAGING.108.838367","article-title":"Influence of myocardial fibrosis on left ventricular diastolic function: noninvasive assessment by cardiac magnetic resonance and echo","volume":"2","author":"Moreo","year":"2009","journal-title":"Circ. Cardiovasc. Imaging."},{"key":"10.1016\/j.jaut.2022.102884_bib42","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1161\/01.RES.0000129254.25507.d6","article-title":"What mechanisms underlie diastolic dysfunction in heart failure?","volume":"94","author":"Kass","year":"2004","journal-title":"Circ. Res."},{"key":"10.1016\/j.jaut.2022.102884_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/pin.12868","article-title":"Inflammation in myocardial disease: from myocarditis to dilated cardiomyopathy","volume":"70","author":"Imanaka-Yoshida","year":"2020","journal-title":"Pathol. Int."},{"key":"10.1016\/j.jaut.2022.102884_bib44","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/art.23352","article-title":"Recent corticosteroid use and recent disease activity: independent determinants of coronary heart disease risk factors in systemic lupus erythematosus?","volume":"59","author":"Karp","year":"2008","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2022.102884_bib45","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3899\/jrheum.190259","article-title":"Effect of disease activity on organ damage progression in systemic lupus erythematosus: university of toronto lupus clinic cohort","volume":"48","author":"Urowitz","year":"2021","journal-title":"J. Rheumatol."}],"container-title":["Journal of Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841122000920?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841122000920?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T08:30:34Z","timestamp":1760257834000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896841122000920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":45,"alternative-id":["S0896841122000920"],"URL":"https:\/\/doi.org\/10.1016\/j.jaut.2022.102884","relation":{},"ISSN":["0896-8411"],"issn-type":[{"value":"0896-8411","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Left ventricular size and function in patients with systemic lupus erythematosus associate with lupus anticoagulant: An echocardiographic follow-up study","name":"articletitle","label":"Article Title"},{"value":"Journal of Autoimmunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaut.2022.102884","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102884"}}