{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T03:29:41Z","timestamp":1792553381803,"version":"4.5.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T00:00:00Z","timestamp":1694995200000},"content-version":"am","delay-in-days":291,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Autoimmunity"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.jaut.2022.102907","type":"journal-article","created":{"date-parts":[[2022,9,18]],"date-time":"2022-09-18T06:24:39Z","timestamp":1663482279000},"page":"102907","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Control of naive and effector CD4 T cell receptor repertoires by rheumatoid-arthritis-risk HLA alleles"],"prefix":"10.1016","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1316-8035","authenticated-orcid":false,"given":"Yasuo","family":"Nagafuchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mineto","family":"Ota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Hatano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariko","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satomi","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai","family":"Okubo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Sugimori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeko","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryochi","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumi","family":"Tsuchida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiko","family":"Iwasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirofumi","family":"Shoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukinori","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiko","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuyoshi","family":"Ishigaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohisa","family":"Okamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keishi","family":"Fujio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaut.2022.102907_bib1","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/nri.2017.143","article-title":"HLA variation and disease","volume":"18","author":"Dendrou","year":"2018","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jaut.2022.102907_bib2","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1038\/ng.3379","article-title":"Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases","volume":"47","author":"Lenz","year":"2015","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jaut.2022.102907_bib3","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1136\/annrheumdis-2018-213678","article-title":"Genetics of rheumatoid arthritis: 2018 status","volume":"78","author":"Okada","year":"2019","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2022.102907_bib4","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/ng.1076","article-title":"Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis","volume":"44","author":"Raychaudhuri","year":"2012","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jaut.2022.102907_bib5","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1084\/jem.20131241","article-title":"A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis","volume":"210","author":"Scally","year":"2013","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jaut.2022.102907_bib6","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/nri1292","article-title":"The many important facets of T-cell repertoire diversity","volume":"4","author":"Nikolich-Zugich","year":"2004","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jaut.2022.102907_bib7","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/gm502","article-title":"Sequence analysis of T-cell repertoires in health and disease","volume":"5","author":"Woodsworth","year":"2013","journal-title":"Genome Med."},{"key":"10.1016\/j.jaut.2022.102907_bib8","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1136\/annrheumdis-2019-215442","article-title":"T cell receptor beta repertoires as novel diagnostic markers for systemic lupus erythematosus and rheumatoid arthritis","volume":"78","author":"Liu","year":"2019","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2022.102907_bib9","doi-asserted-by":"crossref","DOI":"10.1038\/srep12937","article-title":"Quantitative and qualitative characterization of expanded CD4(+) T cell clones in rheumatoid arthritis patients","volume":"5","author":"Ishigaki","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jaut.2022.102907_bib10","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1136\/annrheumdis-2014-206226","article-title":"A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment","volume":"75","author":"Spreafico","year":"2016","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2022.102907_bib11","doi-asserted-by":"crossref","first-page":"905","DOI":"10.3899\/jrheum.170909","article-title":"HLA-DRB1 shared epitope alleles and disease activity are correlated with reduced T cell receptor repertoire diversity in CD4+ T cells in rheumatoid arthritis","volume":"45","author":"Sakurai","year":"2018","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.jaut.2022.102907_bib12","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1038\/ng.3625","article-title":"Genetic variation in MHC proteins is associated with T cell receptor expression biases","volume":"48","author":"Sharon","year":"2016","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jaut.2022.102907_bib13","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.3389\/fimmu.2019.02064","article-title":"Germline-encoded TCR-MHC contacts promote TCR V gene bias in umbilical cord blood T cell repertoire","volume":"10","author":"Gao","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jaut.2022.102907_bib14","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/ng.3822","article-title":"Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire","volume":"49","author":"Emerson","year":"2017","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jaut.2022.102907_bib15","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.1016\/j.cell.2021.03.056","article-title":"Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases","volume":"184","author":"Ota","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.jaut.2022.102907_bib16","first-page":"15","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics (Oxford, England)"},{"key":"10.1016\/j.jaut.2022.102907_bib17","first-page":"166","article-title":"HTSeq--a Python framework to work with high-throughput sequencing data","volume":"31","author":"Anders","year":"2015","journal-title":"Bioinformatics (Oxford, England)"},{"key":"10.1016\/j.jaut.2022.102907_bib18","first-page":"139","article-title":"edgeR: a Bioconductor package for differential expression analysis of digital gene expression data","volume":"26","author":"Robinson","year":"2010","journal-title":"Bioinformatics (Oxford, England)"},{"key":"10.1016\/j.jaut.2022.102907_bib19","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/nprot.2011.457","article-title":"Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses","volume":"7","author":"Stegle","year":"2012","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.jaut.2022.102907_bib20","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1186\/1471-2105-9-559","article-title":"WGCNA: an R package for weighted correlation network analysis","volume":"9","author":"Langfelder","year":"2008","journal-title":"BMC Bioinf."},{"key":"10.1016\/j.jaut.2022.102907_bib21","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1039\/C5MB00663E","article-title":"ReactomePA: an R\/Bioconductor package for reactome pathway analysis and visualization","volume":"12","author":"Yu","year":"2016","journal-title":"Mol. Biosyst."},{"key":"10.1016\/j.jaut.2022.102907_bib22","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/nmeth.3364","article-title":"MiXCR: software for comprehensive adaptive immunity profiling","volume":"12","author":"Bolotin","year":"2015","journal-title":"Nat. Methods"},{"key":"10.1016\/j.jaut.2022.102907_bib23","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/ng.806","article-title":"A framework for variation discovery and genotyping using next-generation DNA sequencing data","volume":"43","author":"DePristo","year":"2011","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jaut.2022.102907_bib24","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13059-018-1388-2","article-title":"Kourami: graph-guided assembly for novel human leukocyte antigen allele discovery","volume":"19","author":"Lee","year":"2018","journal-title":"Genome Biol."},{"key":"10.1016\/j.jaut.2022.102907_bib25","doi-asserted-by":"crossref","first-page":"4394","DOI":"10.1093\/bioinformatics\/btz235","article-title":"HLA*LA-HLA typing from linearly projected graph alignments","volume":"35","author":"Dilthey","year":"2019","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaut.2022.102907_bib26","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.ajhg.2016.06.019","article-title":"Contribution of a non-classical HLA gene, HLA-DOA, to the risk of rheumatoid arthritis","volume":"99","author":"Okada","year":"2016","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jaut.2022.102907_bib27","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms15452","article-title":"A complete tool set for molecular QTL discovery and analysis","volume":"8","author":"Delaneau","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jaut.2022.102907_bib28","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1093\/bioinformatics\/btq419","article-title":"LocusZoom: regional visualization of genome-wide association scan results","volume":"26","author":"Pruim","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaut.2022.102907_bib29","doi-asserted-by":"crossref","first-page":"6916","DOI":"10.1093\/hmg\/ddu387","article-title":"Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations","volume":"23","author":"Okada","year":"2014","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.jaut.2022.102907_bib30","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.38358","article-title":"Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity","volume":"7","author":"DeWitt","year":"2018","journal-title":"Elife"},{"key":"10.1016\/j.jaut.2022.102907_bib31","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1038\/ng.3885","article-title":"Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis","volume":"49","author":"Ishigaki","year":"2017","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jaut.2022.102907_bib32","article-title":"Imputing amino acid polymorphisms in human leukocyte antigens","volume":"8","author":"Jia","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jaut.2022.102907_bib33","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1038\/ng.3310","article-title":"Construction of a population-specific HLA imputation reference panel and its application to Graves' disease risk in Japanese","volume":"47","author":"Okada","year":"2015","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jaut.2022.102907_bib34","series-title":"Combining Genotypes and T Cell Receptor Distributions to Infer Genetic Loci Determining V(D)J Recombination Probabilities","first-page":"11","author":"Russell","year":"2022"},{"key":"10.1016\/j.jaut.2022.102907_bib35","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1136\/annrheumdis-2017-211300","article-title":"Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis","volume":"76","author":"Scally","year":"2017","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2022.102907_bib36","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1002\/art.42021","article-title":"Identification of shared and Asian-specific loci for systemic lupus erythematosus and evidence for roles of type III interferon signaling and lysosomal function in the disease: a multi-ancestral genome-wide association study","volume":"74","author":"Wang","year":"2022","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.jaut.2022.102907_bib37","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1158\/2326-6066.CIR-19-0608","article-title":"CAMK1D triggers immune resistance of human tumor cells refractory to anti-PD-L1 treatment","volume":"8","author":"Volpin","year":"2020","journal-title":"Cancer Immunol. Res."},{"key":"10.1016\/j.jaut.2022.102907_bib38","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.immuni.2009.03.019","article-title":"Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor","volume":"30","author":"Miyara","year":"2009","journal-title":"Immunity"},{"key":"10.1016\/j.jaut.2022.102907_bib39","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1038\/s41588-022-01032-z","article-title":"HLA autoimmune risk alleles restrict the hypervariable region of T cell receptors","volume":"54","author":"Ishigaki","year":"2022","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jaut.2022.102907_bib40","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature12873","article-title":"Genetics of rheumatoid arthritis contributes to biology and drug discovery","volume":"506","author":"Okada","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.jaut.2022.102907_bib41","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.ajhg.2019.03.012","article-title":"IMPACT: genomic annotation of cell-state-specific regulatory elements inferred from the epigenome of bound transcription factors","volume":"104","author":"Amariuta","year":"2019","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jaut.2022.102907_bib42","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1186\/s13075-019-2069-6","article-title":"High-throughput sequencing of CD4","volume":"21","author":"Wang","year":"2019","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.jaut.2022.102907_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2020.102972","article-title":"Ultra-efficient sequencing of T Cell receptor repertoires reveals shared responses in muscle from patients with Myositis","volume":"59","author":"Montagne","year":"2020","journal-title":"EBioMedicine"},{"key":"10.1016\/j.jaut.2022.102907_bib44","doi-asserted-by":"crossref","first-page":"2642","DOI":"10.1172\/JCI98819","article-title":"Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease","volume":"128","author":"Risnes","year":"2018","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jaut.2022.102907_bib45","first-page":"10","article-title":"TCR meta-clonotypes for biomarker discovery with","author":"Mayer-Blackwell","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.jaut.2022.102907_bib46","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1038\/nrd3794","article-title":"Targeting IL-17 and TH17 cells in chronic inflammation","volume":"11","author":"Miossec","year":"2012","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jaut.2022.102907_bib47","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/j.immuni.2015.12.003","article-title":"Th17 cell pathway in human immunity: lessons from genetics and therapeutic interventions","volume":"43","author":"Patel","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.jaut.2022.102907_bib48","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.90045","article-title":"A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22","volume":"1","author":"Chang","year":"2016","journal-title":"JCI Insight"},{"key":"10.1016\/j.jaut.2022.102907_bib49","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/ni.3579","article-title":"Regulation of autoantibody activity by the IL-23-T","volume":"18","author":"Pfeifle","year":"2017","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jaut.2022.102907_bib50","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/art.30093","article-title":"Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production","volume":"63","author":"van Hamburg","year":"2011","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2022.102907_bib51","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.637829","article-title":"Role of the IL-23\/IL-17 pathway in rheumatic diseases: an overview","volume":"12","author":"Schinocca","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jaut.2022.102907_bib52","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1007\/s00296-016-3480-9","article-title":"Anti-IL-17 therapy in treatment of rheumatoid arthritis: a systematic literature review and meta-analysis of randomized controlled trials","volume":"36","author":"Kunwar","year":"2016","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.jaut.2022.102907_bib53","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1007\/s10067-019-04608-z","article-title":"Meta-analysis of IL-17 inhibitors in two populations of rheumatoid arthritis patients: biologic-na\u00efve or tumor necrosis factor inhibitor inadequate responders","volume":"38","author":"Wu","year":"2019","journal-title":"Clin. Rheumatol."}],"container-title":["Journal of Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841122001159?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841122001159?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T08:30:09Z","timestamp":1760257809000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896841122001159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":53,"alternative-id":["S0896841122001159"],"URL":"https:\/\/doi.org\/10.1016\/j.jaut.2022.102907","relation":{},"ISSN":["0896-8411"],"issn-type":[{"value":"0896-8411","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Control of naive and effector CD4 T cell receptor repertoires by rheumatoid-arthritis-risk HLA alleles","name":"articletitle","label":"Article Title"},{"value":"Journal of Autoimmunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaut.2022.102907","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102907"}}