{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T01:10:57Z","timestamp":1781658657968,"version":"3.54.5"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Autoimmunity"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.jaut.2024.103306","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T08:56:27Z","timestamp":1726131387000},"page":"103306","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Alternative splicing and intron retention: Their profiles and roles in cutaneous fibrosis of systemic sclerosis"],"prefix":"10.1016","volume":"149","author":[{"given":"Shasha","family":"Xie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhi","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongdong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muyao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingying","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sijia","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muyuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liqing","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiming","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Liu","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg H.W.","family":"Distler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honglin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"72","key":"10.1016\/j.jaut.2024.103306_bib1","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1136\/annrheumdis-2013-204424","article-title":"Classification criteria for systemic sclerosis: an American college of rheumatology\/European league against rheumatism collaborative initiative","volume":"2013","author":"van den Hoogen","year":"2013","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2024.103306_bib2","article-title":"Systemic sclerosis","volume":"1","author":"Allanore","year":"2015","journal-title":"Nat. Rev. Dis. Prim."},{"key":"10.1016\/j.jaut.2024.103306_bib3","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/nrrheum.2014.53","article-title":"Fibrosis--a lethal component of systemic sclerosis","volume":"10","author":"Ho","year":"2014","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.jaut.2024.103306_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2020.102730","article-title":"Targeted delivery in scleroderma fibrosis","volume":"20","author":"Varrica","year":"2021","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.jaut.2024.103306_bib5","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nature10098","article-title":"Global quantification of mammalian gene expression control","volume":"473","author":"Schwanhausser","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.jaut.2024.103306_bib6","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/s41580-022-00545-z","article-title":"The physiology of alternative splicing","volume":"24","author":"Marasco","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jaut.2024.103306_bib7","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.molcel.2011.12.034","article-title":"Dynamic protein-protein interaction wiring of the human spliceosome","volume":"45","author":"Hegele","year":"2012","journal-title":"Mol Cell"},{"key":"10.1016\/j.jaut.2024.103306_bib8","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1186\/s13059-017-1339-3","article-title":"Intron retention enhances gene regulatory complexity in vertebrates","volume":"18","author":"Schmitz","year":"2017","journal-title":"Genome Biol."},{"key":"10.1016\/j.jaut.2024.103306_bib9","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1126\/science.1228186","article-title":"Evolutionary dynamics of gene and isoform regulation in mammalian tissues","volume":"338","author":"Merkin","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.jaut.2024.103306_bib10","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s13073-015-0168-9","article-title":"Widespread intron retention diversifies most cancer transcriptomes","volume":"7","author":"Dvinge","year":"2015","journal-title":"Genome Med."},{"key":"10.1016\/j.jaut.2024.103306_bib11","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1038\/s41586-018-0859-7","article-title":"Introns are mediators of cell response to starvation","volume":"565","author":"Parenteau","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.jaut.2024.103306_bib12","doi-asserted-by":"crossref","first-page":"6513","DOI":"10.1093\/nar\/gkaa435","article-title":"Macrophage development and activation involve coordinated intron retention in key inflammatory regulators","volume":"48","author":"Green","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jaut.2024.103306_bib13","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/j.neuron.2016.11.032","article-title":"Targeted intron retention and excision for rapid gene regulation in response to neuronal activity","volume":"92","author":"Mauger","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.jaut.2024.103306_bib14","doi-asserted-by":"crossref","first-page":"6817","DOI":"10.1093\/nar\/gkw591","article-title":"Global intron retention mediated gene regulation during CD4+ T cell activation","volume":"44","author":"Ni","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jaut.2024.103306_bib15","doi-asserted-by":"crossref","first-page":"e24","DOI":"10.1182\/blood-2016-01-692764","article-title":"A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages","volume":"127","author":"Edwards","year":"2016","journal-title":"Blood"},{"key":"10.1016\/j.jaut.2024.103306_bib16","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1093\/nar\/gkv1168","article-title":"A dynamic intron retention program enriched in RNA processing genes regulates gene expression during terminal erythropoiesis","volume":"44","author":"Pimentel","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jaut.2024.103306_bib17","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/nature07509","article-title":"Alternative isoform regulation in human tissue transcriptomes","volume":"456","author":"Wang","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.jaut.2024.103306_bib18","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0092-8674(00)00128-8","article-title":"Protein diversity from alternative splicing: a challenge for bioinformatics and post-genome biology","volume":"103","author":"Black","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.jaut.2024.103306_bib19","doi-asserted-by":"crossref","first-page":"4806","DOI":"10.1093\/bioinformatics\/btac561","article-title":"A software package for analyzing various features of gene models","volume":"38","author":"Li","year":"2022","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaut.2024.103306_bib20","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s12864-020-6541-0","article-title":"iREAD: a tool for intron retention detection from RNA-seq data","volume":"21","author":"Li","year":"2020","journal-title":"BMC Genom."},{"key":"10.1016\/j.jaut.2024.103306_bib21","doi-asserted-by":"crossref","DOI":"10.1126\/science.abl4178","article-title":"Complete genomic and epigenetic maps of human centromeres","volume":"376","author":"Altemose","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.jaut.2024.103306_bib22","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1158\/0008-5472.CAN-22-3485","article-title":"Oncogenic transformation drives DNA methylation loss and transcriptional activation at transposable element loci","volume":"83","author":"Kanholm","year":"2023","journal-title":"Cancer Res."},{"key":"10.1016\/j.jaut.2024.103306_bib23","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1002\/alz.12254","article-title":"Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease","volume":"17","author":"Li","year":"2021","journal-title":"Alzheimers Dement"},{"issue":"7","key":"10.1016\/j.jaut.2024.103306_bib24","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1136\/ard-2023-225035","article-title":"Characterised intron retention profiles in muscle tissue of idiopathic inflammatory myopathy subtypes","volume":"83","author":"Xiao","year":"2024","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2024.103306_bib25","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.celrep.2019.08.104","article-title":"Tau-mediated disruption of the spliceosome triggers cryptic RNA splicing and neurodegeneration in Alzheimer's disease","volume":"29","author":"Hsieh","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.jaut.2024.103306_bib26","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2204179119","article-title":"Truncated Tau caused by intron retention is enriched in Alzheimer's disease cortex and exhibits altered biochemical properties","volume":"119","author":"Ngian","year":"2022","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jaut.2024.103306_bib27","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1182\/blood-2005-03-1307","article-title":"Aminoglycoside suppression of nonsense mutations in severe hemophilia","volume":"106","author":"James","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.jaut.2024.103306_bib28","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/nm.4493","article-title":"H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers","volume":"24","author":"Seiler","year":"2018","journal-title":"Nat Med"},{"key":"10.1016\/j.jaut.2024.103306_bib29","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1101\/gad.2009411","article-title":"The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region","volume":"25","author":"Folco","year":"2011","journal-title":"Genes Dev."},{"key":"10.1016\/j.jaut.2024.103306_bib30","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1146\/annurev-med-120611-144851","article-title":"Ataluren as an agent for therapeutic nonsense suppression","volume":"64","author":"Peltz","year":"2013","journal-title":"Annu. Rev. Med."},{"key":"10.1016\/j.jaut.2024.103306_bib31","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/sj.bjc.6604801","article-title":"The spliceosome as target for anticancer treatment","volume":"100","author":"van Alphen","year":"2009","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.jaut.2024.103306_bib32","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1136\/annrheumdis-2019-215894","article-title":"Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile","volume":"79","author":"Skaug","year":"2020","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2024.103306_bib33","volume":"vol. 111","author":"Shen","year":"2014"},{"key":"10.1016\/j.jaut.2024.103306_bib34","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/bioinformatics\/btp616","article-title":"edgeR: a Bioconductor package for differential expression analysis of digital gene expression data","volume":"26","author":"Robinson","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jaut.2024.103306_bib35","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/s41586-020-2941-1","article-title":"Decoding myofibroblast origins in human kidney fibrosis","volume":"589","author":"Kuppe","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.jaut.2024.103306_bib36","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/s13075-021-02548-1","article-title":"Clinical characteristics, visceral involvement, and mortality in at-risk or early diffuse systemic sclerosis: a longitudinal analysis of an observational prospective multicenter US cohort","volume":"23","author":"Jaafar","year":"2021","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.jaut.2024.103306_bib37","doi-asserted-by":"crossref","DOI":"10.1172\/JCI159884","article-title":"Noncanonical WNT5A controls the activation of latent TGF-\u03b2 to drive fibroblast activation and tissue fibrosis","volume":"134","author":"Trinh-Minh","year":"2024","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jaut.2024.103306_bib38","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/S1734-1140(12)70773-9","article-title":"Significance of genetic polymorphism of CYP2D6 in the pathogenesis of systemic sclerosis","volume":"64","author":"Bara\u0144ska","year":"2012","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.jaut.2024.103306_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2020.106886","article-title":"Aryl hydrocarbon receptor signaling activation in systemic sclerosis attenuates collagen production and is a potential antifibrotic target","volume":"88","author":"Shi","year":"2020","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.jaut.2024.103306_bib40","doi-asserted-by":"crossref","first-page":"3308","DOI":"10.1038\/s41467-021-23221-w","article-title":"Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention","volume":"12","author":"Dumbovi\u0107","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jaut.2024.103306_bib41","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s13059-017-1184-4","article-title":"IRFinder: assessing the impact of intron retention on mammalian gene expression","volume":"18","author":"Middleton","year":"2017","journal-title":"Genome Biol."},{"key":"10.1016\/j.jaut.2024.103306_bib42","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1101\/gr.265298.120","article-title":"Widespread intron retention impairs protein homeostasis in C9orf72 ALS brains","volume":"30","author":"Wang","year":"2020","journal-title":"Genome Res."},{"key":"10.1016\/j.jaut.2024.103306_bib43","doi-asserted-by":"crossref","first-page":"3168","DOI":"10.1093\/nar\/gkab115","article-title":"Reactive astrocytes in ALS display diminished intron retention","volume":"49","author":"Ziff","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jaut.2024.103306_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107086","article-title":"Secondhand smoke affects reproductive functions by altering the mouse testis transcriptome, and leads to select intron retention in Pde1a","volume":"161","author":"Tommasi","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.jaut.2024.103306_bib45","doi-asserted-by":"crossref","first-page":"5338","DOI":"10.1158\/1078-0432.CCR-08-2865","article-title":"Cyclin D1 splice variants: polymorphism, risk, and isoform-specific regulation in prostate cancer","volume":"15","author":"Comstock","year":"2009","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jaut.2024.103306_bib46","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1038\/nbt.4239","article-title":"Intron retention is a source of neoepitopes in cancer","volume":"36","author":"Smart","year":"2018","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.jaut.2024.103306_bib47","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1101\/gr.177790.114","article-title":"Widespread intron retention in mammals functionally tunes transcriptomes","volume":"24","author":"Braunschweig","year":"2014","journal-title":"Genome Res."},{"key":"10.1016\/j.jaut.2024.103306_bib48","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1089\/104454900750058107","article-title":"An alternative-exon database and its statistical analysis","volume":"19","author":"Stamm","year":"2000","journal-title":"DNA Cell Biol."},{"key":"10.1016\/j.jaut.2024.103306_bib49","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1471-2164-8-59","article-title":"Sequence features responsible for intron retention in human","volume":"8","author":"Sakabe","year":"2007","journal-title":"BMC Genom."},{"key":"10.1016\/j.jaut.2024.103306_bib50","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.cell.2013.06.052","article-title":"Orchestrated intron retention regulates normal granulocyte differentiation","volume":"154","author":"Wong","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.jaut.2024.103306_bib51","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms15134","article-title":"Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment","volume":"8","author":"Wong","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jaut.2024.103306_bib52","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/annrheumdis-2021-220308","article-title":"Splicing machinery is impaired in rheumatoid arthritis, associated with disease activity and modulated by anti-TNF therapy","volume":"81","author":"Ibanez-Costa","year":"2022","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2024.103306_bib53","doi-asserted-by":"crossref","first-page":"4978","DOI":"10.1093\/emboj\/cdf480","article-title":"Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein","volume":"21","author":"Will","year":"2002","journal-title":"The EMBO journal"},{"key":"10.1016\/j.jaut.2024.103306_bib54","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.celrep.2018.09.041","article-title":"RBM17 interacts with U2SURP and CHERP to regulate expression and splicing of RNA-processing proteins","volume":"25","author":"De Maio","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.jaut.2024.103306_bib55","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1006\/clim.1999.4745","article-title":"Diverse antibody recognition patterns of the multiple Sm-D antigen polypeptides","volume":"92","author":"Hoch","year":"1999","journal-title":"Clin. Immunol."}],"container-title":["Journal of Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841124001409?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841124001409?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T11:40:30Z","timestamp":1738496430000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896841124001409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":55,"alternative-id":["S0896841124001409"],"URL":"https:\/\/doi.org\/10.1016\/j.jaut.2024.103306","relation":{},"ISSN":["0896-8411"],"issn-type":[{"value":"0896-8411","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alternative splicing and intron retention: Their profiles and roles in cutaneous fibrosis of systemic sclerosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Autoimmunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaut.2024.103306","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103306"}}