{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T03:30:06Z","timestamp":1792553406053,"version":"4.5.0"},"reference-count":134,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004480","name":"Natural Science Foundation of Shanxi Province","doi-asserted-by":"publisher","award":["202203021221269"],"award-info":[{"award-number":["202203021221269"]}],"id":[{"id":"10.13039\/501100004480","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82001740"],"award-info":[{"award-number":["82001740"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Autoimmunity"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.jaut.2025.103433","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T12:26:51Z","timestamp":1746534411000},"page":"103433","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["The role of age-associated B cells in systemic lupus erythematosus"],"prefix":"10.1016","volume":"154","author":[{"given":"Qin-Yi","family":"Su","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Xin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Ting","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Ru","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1341-7588","authenticated-orcid":false,"given":"Sheng-Xiao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Feng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jaut.2025.103433_bib1","doi-asserted-by":"crossref","first-page":"541","DOI":"10.3389\/fimmu.2018.00541","article-title":"Autoantibodies associated with connective tissue diseases: what meaning for clinicians?","volume":"9","author":"Didier","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib2","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1016\/S0140-6736(24)00398-2","article-title":"Systemic lupus erythematosus","volume":"403","author":"Hoi","year":"2024","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.jaut.2025.103433_bib3","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/s41577-018-0107-2","article-title":"B cells still front and centre in immunology","volume":"19","author":"Tarlinton","year":"2019","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib4","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1182\/blood-2011-01-330530","article-title":"A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice","volume":"118","author":"Hao","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.jaut.2025.103433_bib5","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1182\/blood-2011-01-331462","article-title":"Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity","volume":"118","author":"Rubtsov","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.jaut.2025.103433_bib6","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1038\/s41590-019-0398-x","article-title":"The immune cell landscape in kidneys of patients with lupus nephritis","volume":"20","author":"Arazi","year":"2019","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib7","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.cellimm.2017.04.007","article-title":"Aging effects on T-bet expression in human B cell subsets","volume":"321","author":"Frasca","year":"2017","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib8","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.684999","article-title":"The multiple roles of B cells in the pathogenesis of sj\u00f6gren's syndrome","volume":"12","author":"Du","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellimm.2022.104533","article-title":"Age-associated B cells indicate disease activity in rheumatoid arthritis","volume":"377","author":"Bao","year":"2022","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib10","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.immuni.2020.03.020","article-title":"The transcription factor T-bet resolves memory B cell subsets with distinct tissue distributions and antibody specificities in mice and humans","volume":"52","author":"Johnson","year":"2020","journal-title":"Immunity"},{"key":"10.1016\/j.jaut.2025.103433_bib11","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1111\/imm.13598","article-title":"Characterization of age-associated B cells in early drug-na\u00efve rheumatoid arthritis patients","volume":"168","author":"Vidal-Pedrola","year":"2023","journal-title":"Immunology"},{"key":"10.1016\/j.jaut.2025.103433_bib12","doi-asserted-by":"crossref","first-page":"118","DOI":"10.5152\/eurjrheum.2018.17096","article-title":"Outcomes of rituximab therapy in refractory lupus: a meta-analysis","volume":"5","author":"Alshaiki","year":"2018","journal-title":"Eur. J. Rheumatol."},{"key":"10.1016\/j.jaut.2025.103433_bib13","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1002\/art.20430","article-title":"B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I\/II dose-escalation trial of rituximab","volume":"50","author":"Looney","year":"2004","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2025.103433_bib14","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.826152","article-title":"Rituximab in systemic lupus erythematosus: transient effects on autoimmunity associated lymphocyte phenotypes and implications for immunogenicity","volume":"13","author":"Faustini","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib15","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1186\/s13075-017-1438-2","article-title":"T-bet(+)CD11c(+) B cells are critical for antichromatin immunoglobulin G production in the development of lupus","volume":"19","author":"Liu","year":"2017","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.jaut.2025.103433_bib16","doi-asserted-by":"crossref","first-page":"4576","DOI":"10.4049\/jimmunol.1502448","article-title":"Age-associated B cells with proinflammatory characteristics are expanded in a proportion of multiple sclerosis patients","volume":"197","author":"Claes","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib17","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1002\/art.37828","article-title":"Expansion of autoreactive unresponsive CD21-\/low B cells in Sj\u00f6gren's syndrome-associated lymphoproliferation","volume":"65","author":"Saadoun","year":"2013","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2025.103433_bib18","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1007\/s00018-022-04433-9","article-title":"Age-associated B cells in autoimmune diseases","volume":"79","author":"Mouat","year":"2022","journal-title":"Cell. Mol. Life Sci. : CMLS"},{"key":"10.1016\/j.jaut.2025.103433_bib19","article-title":"Age\/autoimmunity-associated B cells in inflammatory arthritis: an emerging therapeutic target","volume":"14","author":"Li","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib20","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/imr.12380","article-title":"Age-associated B cells: key mediators of both protective and autoreactive humoral responses","volume":"269","author":"Naradikian","year":"2016","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.jaut.2025.103433_bib21","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.4049\/jimmunol.1501209","article-title":"Age-associated B cells: a T-bet-dependent effector with roles in protective and pathogenic immunity","volume":"195","author":"Rubtsova","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib22","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1146\/annurev-immunol-092419-031130","article-title":"Age-associated B cells","volume":"38","author":"Cancro","year":"2020","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib23","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20221346","article-title":"Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice","volume":"220","author":"Nickerson","year":"2023","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jaut.2025.103433_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006576","article-title":"Malaria-induced interferon-\u03b3 drives the expansion of Tbethi atypical memory B cells","volume":"13","author":"Obeng-Adjei","year":"2017","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jaut.2025.103433_bib25","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1089\/dna.2016.3304","article-title":"T-bet-Expressing B cells are positively associated with Crohn's disease activity and support Th1 inflammation","volume":"35","author":"Wang","year":"2016","journal-title":"DNA Cell Biol."},{"key":"10.1016\/j.jaut.2025.103433_bib26","doi-asserted-by":"crossref","first-page":"18550","DOI":"10.1073\/pnas.1901340116","article-title":"Excessive CD11c(+)Tbet(+) B cells promote aberrant T(FH) differentiation and affinity-based germinal center selection in lupus","volume":"116","author":"Zhang","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.jaut.2025.103433_bib27","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.cellimm.2017.05.008","article-title":"Role of CD11c(+) T-bet(+) B cells in human health and disease","volume":"321","author":"Karnell","year":"2017","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib28","doi-asserted-by":"crossref","first-page":"311","DOI":"10.31138\/mjr.31.3.311","article-title":"Age-associated B cells (ABCs) in the prognosis, diagnosis and therapy of systemic lupus erythematosus (SLE)","volume":"31","author":"Sachinidis","year":"2020","journal-title":"Mediterr. J. Rheumatol."},{"key":"10.1016\/j.jaut.2025.103433_bib29","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.41641","article-title":"IFN\u03b3 induces epigenetic programming of human T-bet(hi) B cells and promotes TLR7\/8 and IL-21 induced differentiation","volume":"8","author":"Zumaquero","year":"2019","journal-title":"Elife"},{"key":"10.1016\/j.jaut.2025.103433_bib30","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.immuni.2018.08.015","article-title":"Distinct effector B cells induced by unregulated toll-like receptor 7 contribute to pathogenic responses in systemic lupus erythematosus","volume":"49","author":"Jenks","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.jaut.2025.103433_bib31","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.coi.2018.09.007","article-title":"Age (autoimmunity) associated B cells (ABCs) and their relatives","volume":"55","author":"Phalke","year":"2018","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib32","doi-asserted-by":"crossref","first-page":"4813","DOI":"10.1038\/s41467-021-25102-8","article-title":"Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice","volume":"12","author":"Ricker","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jaut.2025.103433_bib33","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1038\/s41467-018-03750-7","article-title":"IL-21 drives expansion and plasma cell differentiation of autoreactive CD11c(hi)T-bet(+) B cells in SLE","volume":"9","author":"Wang","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jaut.2025.103433_bib34","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1172\/JCI96798","article-title":"Early B cell changes predict autoimmunity following combination immune checkpoint blockade","volume":"128","author":"Das","year":"2018","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.jaut.2025.103433_bib35","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1172\/JCI91250","article-title":"B cells expressing the transcription factor T-bet drive lupus-like autoimmunity","volume":"127","author":"Rubtsova","year":"2017","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.jaut.2025.103433_bib36","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.coi.2019.07.008","article-title":"Molecular pattern recognition in peripheral B cell tolerance: lessons from age-associated B cells","volume":"61","author":"Johnson","year":"2019","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib37","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.4049\/jimmunol.1601106","article-title":"Age-associated B cells express a diverse repertoire of V(H) and V\u03ba genes with somatic hypermutation","volume":"198","author":"Russell Knode","year":"2017","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib38","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.immuni.2022.01.002","article-title":"Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers","volume":"55","author":"Song","year":"2022","journal-title":"Immunity"},{"key":"10.1016\/j.jaut.2025.103433_bib39","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.4049\/jimmunol.1900404","article-title":"Functional characterization of CD11c(+) age-associated B cells as memory B cells","volume":"203","author":"Du","year":"2019","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellimm.2019.103966","article-title":"B cells from young and old mice switch isotypes with equal frequencies after ex vivo stimulation","volume":"345","author":"Russell Knode","year":"2019","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib41","doi-asserted-by":"crossref","first-page":"71","DOI":"10.4049\/jimmunol.1500055","article-title":"CD11c-Expressing B cells are located at the T cell\/B cell border in spleen and are potent APCs","volume":"195","author":"Rubtsov","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib42","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1241531","article-title":"Phenotypic and functional characteristics of murine CD11c+ B cells which is suppressed by metformin","volume":"14","author":"Ramirez De Oleo","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib43","doi-asserted-by":"crossref","DOI":"10.1111\/acel.13692","article-title":"B cell-intrinsic changes with age do not impact antibody-secreting cell formation but delay B cell participation in the germinal centre reaction","volume":"21","author":"Lee","year":"2022","journal-title":"Aging Cell"},{"key":"10.1016\/j.jaut.2025.103433_bib44","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1084\/jem.20102065","article-title":"B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells","volume":"208","author":"Lee","year":"2011","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jaut.2025.103433_bib45","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.immuni.2012.11.017","article-title":"Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus","volume":"38","author":"Teichmann","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.jaut.2025.103433_bib46","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/imr.12741","article-title":"Extrafollicular responses in humans and SLE","volume":"288","author":"Jenks","year":"2019","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.jaut.2025.103433_bib47","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1126\/science.adf8531","article-title":"The transcription factor ZEB2 drives the formation of age-associated B cells","volume":"383","author":"Dai","year":"2024","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.jaut.2025.103433_bib48","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/eji.201847641","article-title":"Generation of functional murine CD11c(+) age-associated B cells in the absence of B cell T-bet expression","volume":"49","author":"Du","year":"2019","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib49","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.4049\/jimmunol.1500368","article-title":"Cutting edge: B cell-intrinsic T-bet expression is required to control chronic viral infection","volume":"197","author":"Barnett","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib50","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.cellimm.2014.12.002","article-title":"TLR7, IFN\u03b3, and T-bet: their roles in the development of ABCs in female-biased autoimmunity","volume":"294","author":"Rubtsova","year":"2015","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib51","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.cell.2020.02.041","article-title":"Toll-like receptors and the control of immunity","volume":"180","author":"Fitzgerald","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.jaut.2025.103433_bib52","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41586-022-04642-z","article-title":"TLR7 gain-of-function genetic variation causes human lupus","volume":"605","author":"Brown","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.jaut.2025.103433_bib53","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/ni941","article-title":"CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells","volume":"4","author":"Liu","year":"2003","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib54","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1038\/s41584-020-00544-4","article-title":"Toll-like receptor signalling in B cells during systemic lupus erythematosus","volume":"17","author":"Fillatreau","year":"2021","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.jaut.2025.103433_bib55","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1038\/s41590-022-01310-2","article-title":"Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus","volume":"23","author":"Leibler","year":"2022","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib56","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.4049\/jimmunol.1600522","article-title":"Cutting edge: IL-4, IL-21, and IFN-\u03b3 interact to govern T-bet and CD11c expression in TLR-activated B cells","volume":"197","author":"Naradikian","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib57","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.4049\/jimmunol.2000206","article-title":"CD11c(+) T-bet(+) B cells require IL-21 and IFN-\u03b3 from type 1 T follicular helper cells and intrinsic Bcl-6 expression but develop normally in the absence of T-bet","volume":"205","author":"Levack","year":"2020","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib58","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1002\/art.42146","article-title":"Interleukin-13 receptor \u03b11-mediated signaling regulates age-associated\/autoimmune B cell expansion and lupus pathogenesis","volume":"74","author":"Chen","year":"2022","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.jaut.2025.103433_bib59","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1002\/art.30183","article-title":"Interferon regulatory factor 5 is critical for the development of lupus in MRL\/lpr mice","volume":"63","author":"Tada","year":"2011","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2025.103433_bib60","doi-asserted-by":"crossref","first-page":"eadj4748","DOI":"10.1126\/sciimmunol.adj4748","article-title":"Zeb2 drives the formation of CD11c(+) atypical B cells to sustain germinal centers that control persistent infection","volume":"9","author":"Gao","year":"2024","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib61","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.adk1643","article-title":"Age-associated CD4(+) T cells with B cell-promoting functions are regulated by ZEB2 in autoimmunity","volume":"9","author":"Goto","year":"2024","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib62","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/s41584-020-0472-7","article-title":"The (Orf)ull truth about IRF5 and type I interferons in SLE","volume":"16","author":"Elkon","year":"2020","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.jaut.2025.103433_bib63","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1007\/s11926-021-01047-1","article-title":"TLR7 signaling in lupus B cells: new insights into synergizing factors and downstream signals","volume":"23","author":"Satterthwaite","year":"2021","journal-title":"Curr. Rheumatol. Rep."},{"key":"10.1016\/j.jaut.2025.103433_bib64","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.1002\/eji.201646573","article-title":"The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling","volume":"46","author":"Desnues","year":"2016","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib65","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/intimm\/dxy032","article-title":"Regulation and role of the transcription factor IRF5 in innate immune responses and systemic lupus erythematosus","volume":"30","author":"Ban","year":"2018","journal-title":"Int. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib66","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.cellimm.2017.05.010","article-title":"Regulation of systemic autoimmunity and CD11c(+) Tbet(+) B cells by SWEF proteins","volume":"321","author":"Manni","year":"2017","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib67","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/s41590-018-0056-8","article-title":"Regulation of age-associated B cells by IRF5 in systemic autoimmunity","volume":"19","author":"Manni","year":"2018","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib68","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/ng.3496","article-title":"High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry","volume":"48","author":"Sun","year":"2016","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jaut.2025.103433_bib69","doi-asserted-by":"crossref","first-page":"2164","DOI":"10.1038\/s41467-019-10106-2","article-title":"Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus","volume":"10","author":"Odhams","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jaut.2025.103433_bib70","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/s41586-020-2282-0","article-title":"TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9","volume":"581","author":"Heinz","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.jaut.2025.103433_bib71","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112916","article-title":"SLC15A4 controls endolysosomal TLR7-9 responses by recruiting the innate immune adaptor TASL","volume":"42","author":"Zhang","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.jaut.2025.103433_bib72","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/nrd4296","article-title":"Interleukin-21: a double-edged sword with therapeutic potential","volume":"13","author":"Spolski","year":"2014","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jaut.2025.103433_bib73","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20236021","article-title":"Multiple functions of B cells in the pathogenesis of systemic lupus erythematosus","volume":"20","author":"Ma","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jaut.2025.103433_bib74","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.4049\/jimmunol.2300027","article-title":"Cutting edge: IL-21 and tissue-specific signals instruct Tbet+CD11c+ B cell development following viral infection","volume":"210","author":"Song","year":"2023","journal-title":"J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib75","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.ade6844","article-title":"Gammaherpesvirus infection drives age-associated B cells toward pathogenicity in EAE and MS","volume":"8","author":"Mouat","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jaut.2025.103433_bib76","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.67024","article-title":"Latent gammaherpesvirus exacerbates arthritis through modification of age-associated B cells","volume":"10","author":"Mouat","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.jaut.2025.103433_bib77","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1136\/ard-2022-222605","article-title":"Age-associated B cells contribute to the pathogenesis of rheumatoid arthritis by inducing activation of fibroblast-like synoviocytes via TNF-\u03b1-mediated ERK1\/2 and JAK-STAT1 pathways","volume":"81","author":"Qin","year":"2022","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2025.103433_bib78","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s12016-016-8550-y","article-title":"The role of STAT signaling pathways in the pathogenesis of systemic lupus erythematosus","volume":"52","author":"Goropev\u0161ek","year":"2017","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib79","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.110259","article-title":"Uncontrolled CD21(low) age-associated and B1 B cell accumulation caused by failure of an EGR2\/3 tolerance checkpoint","volume":"38","author":"Masle-Farquhar","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.jaut.2025.103433_bib80","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2021.102686","article-title":"A novel humanized cutaneous lupus erythematosus mouse model mediated by IL-21-induced age-associated B cells","volume":"123","author":"Zhou","year":"2021","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.jaut.2025.103433_bib81","doi-asserted-by":"crossref","first-page":"5545","DOI":"10.1073\/pnas.082114899","article-title":"T-bet regulates IgG class switching and pathogenic autoantibody production","volume":"99","author":"Peng","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.jaut.2025.103433_bib82","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s12979-021-00222-3","article-title":"Hyper-metabolic B cells in the spleens of old mice make antibodies with autoimmune specificities","volume":"18","author":"Frasca","year":"2021","journal-title":"Immun. Ageing : Ir. Am."},{"key":"10.1016\/j.jaut.2025.103433_bib83","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/acel.12055","article-title":"In senescence, age-associated B cells secrete TNF\u03b1 and inhibit survival of B-cell precursors","volume":"12","author":"Ratliff","year":"2013","journal-title":"Aging Cell"},{"key":"10.1016\/j.jaut.2025.103433_bib84","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/347141","article-title":"Roles of pro- and anti-inflammatory cytokines in the pathogenesis of SLE","volume":"2012","author":"Su","year":"2012","journal-title":"J. Biomed. Biotechnol."},{"key":"10.1016\/j.jaut.2025.103433_bib85","first-page":"551","volume":"vol. 36","author":"Frasca","year":"2020"},{"key":"10.1016\/j.jaut.2025.103433_bib86","doi-asserted-by":"crossref","first-page":"E3216","DOI":"10.1073\/pnas.1312348110","article-title":"T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance","volume":"110","author":"Rubtsova","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.jaut.2025.103433_bib87","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1586\/eci.11.83","article-title":"Age-associated B cells: are they the key to understanding why autoimmune diseases are more prevalent in women?","volume":"8","author":"Rubtsova","year":"2012","journal-title":"Expet Rev. Clin. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib88","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aap8855","article-title":"TLR7 escapes X chromosome inactivation in immune cells","volume":"3","author":"Souyris","year":"2018","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib89","doi-asserted-by":"crossref","DOI":"10.1136\/rmdopen-2020-001258","article-title":"Therapeutic implications of the anergic\/postactivated status of B cells in systemic lupus erythematosus","volume":"6","author":"D\u00f6rner","year":"2020","journal-title":"RMD Open"},{"key":"10.1016\/j.jaut.2025.103433_bib90","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.3389\/fimmu.2019.02136","article-title":"Identification and characterization of post-activated B cells in systemic autoimmune diseases","volume":"10","author":"Wei\u00dfenberg","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib91","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.130655","article-title":"Serine\/threonine phosphatase PP2A is essential for optimal B cell function","volume":"5","author":"Meidan","year":"2020","journal-title":"JCI insight"},{"key":"10.1016\/j.jaut.2025.103433_bib92","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/s41573-020-00092-2","article-title":"B cell depletion therapies in autoimmune disease: advances and mechanistic insights","volume":"20","author":"Lee","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jaut.2025.103433_bib93","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/s41584-024-01210-9","article-title":"Opportunities and limitations of B cell depletion approaches in SLE","volume":"21","author":"Stockfelt","year":"2025","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.jaut.2025.103433_bib94","doi-asserted-by":"crossref","DOI":"10.1016\/j.imlet.2024.106962","article-title":"Early decrease of T-bet(+) B cells during subcutaneous belimumab predicts response to therapy in systemic lupus erythematosus patients","volume":"272","author":"La Gualana","year":"2025","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.jaut.2025.103433_bib95","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1002\/art.42433","article-title":"Amelioration of autoimmunity in a lupus mouse model by modulation of T-bet-promoted energy metabolism in pathogenic age\/autoimmune-associated B cells","volume":"75","author":"Han","year":"2023","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.jaut.2025.103433_bib96","doi-asserted-by":"crossref","first-page":"6627","DOI":"10.1038\/s41467-023-42210-9","article-title":"Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling","volume":"14","author":"Chen","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jaut.2025.103433_bib97","doi-asserted-by":"crossref","first-page":"18119","DOI":"10.1021\/acsnano.2c04871","article-title":"PEGylated gold nanoparticles target age-associated B cells in vivo","volume":"16","author":"Ho\u010devar","year":"2022","journal-title":"ACS Nano"},{"key":"10.1016\/j.jaut.2025.103433_bib98","doi-asserted-by":"crossref","first-page":"2124","DOI":"10.1038\/s41591-022-02017-5","article-title":"Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus","volume":"28","author":"Mackensen","year":"2022","journal-title":"Nat. Med."},{"key":"10.1016\/j.jaut.2025.103433_bib99","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aaf7153","article-title":"PTPN22 inhibition resets defective human central B cell tolerance","volume":"1","author":"Schickel","year":"2016","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib100","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/ar1180","article-title":"Ageing, autoimmunity and arthritis: senescence of the B cell compartment - implications for humoral immunity","volume":"6","author":"Johnson","year":"2004","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.jaut.2025.103433_bib101","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.autrev.2005.09.008","article-title":"Aging of the immune system: a risk factor for autoimmunity?","volume":"5","author":"Prelog","year":"2006","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.jaut.2025.103433_bib102","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1159\/000478012","article-title":"Autoimmunity in the elderly: insights from basic science and clinics - a mini-review","volume":"63","author":"Watad","year":"2017","journal-title":"Gerontology"},{"key":"10.1016\/j.jaut.2025.103433_bib103","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/s41590-021-00927-z","article-title":"Hallmarks of T cell aging","volume":"22","author":"Mittelbrunn","year":"2021","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib104","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.exger.2017.10.024","article-title":"Age and immunity: what is \"immunosenescence\"","volume":"105","author":"Pawelec","year":"2018","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.jaut.2025.103433_bib105","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3109\/09513590.2013.852531","article-title":"The immune system and aging: a review","volume":"30","author":"Castelo-Branco","year":"2014","journal-title":"Gynecol. Endocrinol. : Off. J. Int. Soc. Gynecol. Endocrinol."},{"key":"10.1016\/j.jaut.2025.103433_bib106","first-page":"437","article-title":"The origin and implication of thymic involution","volume":"2","author":"Aw","year":"2011","journal-title":"Aging Dis."},{"key":"10.1016\/j.jaut.2025.103433_bib107","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1089\/ars.2010.3228","article-title":"Aging and immune function: molecular mechanisms to interventions","volume":"14","author":"Ponnappan","year":"2011","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.jaut.2025.103433_bib108","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1298004","article-title":"From aging to long COVID: exploring the convergence of immunosenescence, inflammaging, and autoimmunity","volume":"14","author":"M\u00fcller","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib109","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12979-020-0173-8","article-title":"Contributions of age-related thymic involution to immunosenescence and inflammaging","volume":"17","author":"Thomas","year":"2020","journal-title":"Immun. Ageing : Ir. Am."},{"key":"10.1016\/j.jaut.2025.103433_bib110","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.exger.2016.12.001","article-title":"Human peripheral late\/exhausted memory B cells express a senescent-associated secretory phenotype and preferentially utilize metabolic signaling pathways","volume":"87","author":"Frasca","year":"2017","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.jaut.2025.103433_bib111","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1742-4933-10-14","article-title":"Effects of age on H1N1-specific serum IgG1 and IgG3 levels evaluated during the 2011-2012 influenza vaccine season","volume":"10","author":"Frasca","year":"2013","journal-title":"Immun. Ageing : Ir. Am."},{"key":"10.1016\/j.jaut.2025.103433_bib112","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/j.1749-6632.2000.tb06651.x","article-title":"Inflamm-aging. An evolutionary perspective on immunosenescence","volume":"908","author":"Franceschi","year":"2000","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.jaut.2025.103433_bib113","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/art.11445","article-title":"Prognostic markers of radiographic progression in early rheumatoid arthritis","volume":"50","author":"Goronzy","year":"2004","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2025.103433_bib114","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.799380","article-title":"Immunosenescence and autoimmunity: exploiting the T-cell receptor repertoire to investigate the impact of aging on multiple sclerosis","volume":"12","author":"Amoriello","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib115","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jaut.2006.10.002","article-title":"Antinuclear antibodies in the oldest-old women and men","volume":"27","author":"Nilsson","year":"2006","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.jaut.2025.103433_bib116","first-page":"677","article-title":"Drug-induced autoimmunity, Best practice & research","volume":"18","author":"Olsen","year":"2004","journal-title":"Clin. Rheumatol."},{"key":"10.1016\/j.jaut.2025.103433_bib117","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1136\/ard.2003.020198","article-title":"Antinuclear antibodies are common in an infectious environment but do not predict systemic lupus erythematosus","volume":"63","author":"Cainelli","year":"2004","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2025.103433_bib118","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/s41392-023-01451-2","article-title":"Immunosenescence: molecular mechanisms and diseases","volume":"8","author":"Liu","year":"2023","journal-title":"Signal Transduct. Targeted Ther."},{"key":"10.1016\/j.jaut.2025.103433_bib119","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1586\/1744666X.2013.816479","article-title":"B-cell-targeted therapies in systemic lupus erythematosus and ANCA-associated vasculitis: current progress","volume":"9","author":"Md Yusof","year":"2013","journal-title":"Expet Rev. Clin. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib120","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.autrev.2011.11.007","article-title":"B-cell depleting agents for ANCA vasculitides: a new therapeutic approach","volume":"11","author":"G\u00f3mez-Puerta","year":"2012","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.jaut.2025.103433_bib121","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1186\/s13075-020-02215-x","article-title":"Favorable efficacy of rituximab in ANCA-associated vasculitis patients with excessive B cell differentiation","volume":"22","author":"Miyazaki","year":"2020","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.jaut.2025.103433_bib122","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.150999","article-title":"Circulating autoreactive proteinase 3+ B cells and tolerance checkpoints in ANCA-associated vasculitis","volume":"6","author":"Berti","year":"2021","journal-title":"JCI insight"},{"key":"10.1016\/j.jaut.2025.103433_bib123","doi-asserted-by":"crossref","first-page":"R70","DOI":"10.1186\/ar4247","article-title":"Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA)","volume":"15","author":"Abdulahad","year":"2013","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.jaut.2025.103433_bib124","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1002\/eji.202049093","article-title":"Altered follicular regulatory T (Tfr)- and helper T (Tfh)-cell subsets are associated with autoantibody levels in microscopic polyangiitis patients","volume":"51","author":"Long","year":"2021","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib125","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s12016-017-8608-5","article-title":"Could lymphocyte profiling be useful to diagnose systemic autoimmune diseases?","volume":"53","author":"Carvajal Alegria","year":"2017","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"10.1016\/j.jaut.2025.103433_bib126","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/8209737","article-title":"Increased frequencies of switched memory B cells and plasmablasts in peripheral blood from patients with ANCA-associated vasculitis","volume":"2020","author":"Elm\u00e9r","year":"2020","journal-title":"j. Immunol. Res"},{"key":"10.1016\/j.jaut.2025.103433_bib127","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1136\/ard-2024-225587","article-title":"Defects in B-lymphopoiesis and B-cell maturation underlie prolonged B-cell depletion in ANCA-associated vasculitis","volume":"83","author":"Thiel","year":"2024","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jaut.2025.103433_bib128","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/art.37715","article-title":"2012 revised international chapel hill consensus conference nomenclature of vasculitides","volume":"65","author":"Jennette","year":"2013","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jaut.2025.103433_bib129","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1038\/s41467-025-56786-x","article-title":"Anti-myeloperoxidase IgM B cells in anti-neutrophil cytoplasmic antibody-associated vasculitis","volume":"16","author":"Wortel","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jaut.2025.103433_bib130","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1038\/s41467-024-45201-6","article-title":"T-bet(+) B cells are activated by and control endogenous retroviruses through TLR-dependent mechanisms","volume":"15","author":"Rauch","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jaut.2025.103433_bib131","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/1756-185X.14259","article-title":"COVID-19 vaccination can occasionally trigger autoimmune phenomena, probably via inducing age-associated B cells","volume":"25","author":"Mahroum","year":"2022","journal-title":"Int. J. Rheum. Dis."},{"key":"10.1016\/j.jaut.2025.103433_bib132","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002715","article-title":"Gammaherpesvirus latency accentuates EAE pathogenesis: relevance to Epstein-Barr virus and multiple sclerosis","volume":"8","author":"Casiraghi","year":"2012","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jaut.2025.103433_bib133","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/j.immuni.2014.10.016","article-title":"Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation","volume":"41","author":"Matsumoto","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.jaut.2025.103433_bib134","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.1172\/JCI119856","article-title":"An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus","volume":"100","author":"James","year":"1997","journal-title":"J. Clin. Investig."}],"container-title":["Journal of Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841125000782?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841125000782?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T07:07:44Z","timestamp":1749712064000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896841125000782"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":134,"alternative-id":["S0896841125000782"],"URL":"https:\/\/doi.org\/10.1016\/j.jaut.2025.103433","relation":{},"ISSN":["0896-8411"],"issn-type":[{"value":"0896-8411","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of age-associated B cells in systemic lupus erythematosus","name":"articletitle","label":"Article Title"},{"value":"Journal of Autoimmunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jaut.2025.103433","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103433"}}