{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T01:23:15Z","timestamp":1788571395924,"version":"build-2803163510"},"reference-count":61,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T00:00:00Z","timestamp":1638230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001823","name":"Ministry of Education Youth and Sports of the Czech Republic","doi-asserted-by":"publisher","award":["CZ.2.16\/3.1.00\/21527"],"award-info":[{"award-number":["CZ.2.16\/3.1.00\/21527"]}],"id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003193","name":"Ministry of Education Science Research and Sport of the Slovak Republic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003193","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005357","name":"Slovak Research and Development Agency","doi-asserted-by":"publisher","award":["APVV-20-0129"],"award-info":[{"award-number":["APVV-20-0129"]}],"id":[{"id":"10.13039\/501100005357","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010783","name":"Slovensk\u00e1 Akad\u00e9mia Vied","doi-asserted-by":"publisher","award":["SAV-18\\u201325"],"award-info":[{"award-number":["SAV-18\\u201325"]}],"id":[{"id":"10.13039\/100010783","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010783","name":"Slovensk\u00e1 Akad\u00e9mia Vied","doi-asserted-by":"publisher","award":["SAS-MOST JRP 2016\/4"],"award-info":[{"award-number":["SAS-MOST JRP 2016\/4"]}],"id":[{"id":"10.13039\/100010783","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010783","name":"Slovensk\u00e1 Akad\u00e9mia Vied","doi-asserted-by":"publisher","award":["2\/0165\/18"],"award-info":[{"award-number":["2\/0165\/18"]}],"id":[{"id":"10.13039\/100010783","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001824","name":"Czech Science Foundation","doi-asserted-by":"publisher","award":["19\\u201304052S"],"award-info":[{"award-number":["19\\u201304052S"]}],"id":[{"id":"10.13039\/501100001824","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.jbc.2021.101462","type":"journal-article","created":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T11:10:00Z","timestamp":1638443400000},"page":"101462","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Blocking phosphatidylglycerol degradation in yeast defective in cardiolipin remodeling results in a new model of the Barth syndrome cellular phenotype"],"prefix":"10.1016","volume":"298","author":[{"given":"Paul\u00edna","family":"K\u00e1\u0148ovi\u010dov\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"\u010cerm\u00e1kov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominika","family":"Kubalov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"B\u00e1belov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Vesel\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7096-9325","authenticated-orcid":false,"given":"Martin","family":"Valachovi\u010d","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8332-9789","authenticated-orcid":false,"given":"Jakub","family":"Zahumensk\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0785-4204","authenticated-orcid":false,"given":"Anton","family":"Horv\u00e1th","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1433-0989","authenticated-orcid":false,"given":"Jan","family":"Mal\u00ednsk\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8113-6855","authenticated-orcid":false,"given":"M\u00e1ria","family":"Bal\u00e1\u017eov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbc.2021.101462_bib1","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1002\/1873-3468.12887","article-title":"The role of nonbilayer phospholipids in mitochondrial structure and function","volume":"592","author":"Basu Ball","year":"2018","journal-title":"FEBS Lett."},{"key":"10.1016\/j.jbc.2021.101462_bib2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.biochi.2017.05.005","article-title":"Specific roles of phosphatidylglycerols in hosts and microbes","volume":"141","author":"Dugail","year":"2017","journal-title":"Biochimie"},{"key":"10.1016\/j.jbc.2021.101462_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12154-016-0159-3","article-title":"Is phosphatidylglycerol essential for terrestrial life?","volume":"10","author":"Furse","year":"2017","journal-title":"J.\u00a0Chem. Biol."},{"key":"10.1016\/j.jbc.2021.101462_bib4","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s10265-004-0183-1","article-title":"Roles of the acidic lipids sulfoquinovosyl diacylglycerol and phosphatidylglycerol in photosynthesis: Their specificity and evolution","volume":"117","author":"Sato","year":"2004","journal-title":"J.\u00a0Plant Res."},{"key":"10.1016\/j.jbc.2021.101462_bib5","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1186\/rr86","article-title":"Surfactant alteration and replacement in acute respiratory distress syndrome","volume":"2","author":"G\u00fcnther","year":"2001","journal-title":"Respir. Res."},{"key":"10.1016\/j.jbc.2021.101462_bib6","doi-asserted-by":"crossref","first-page":"4282","DOI":"10.1074\/jbc.AW118.003229","article-title":"Phospholipid regulation of innate immunity and respiratory viral infection","volume":"294","author":"Voelker","year":"2019","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib7","doi-asserted-by":"crossref","first-page":"22387","DOI":"10.1074\/jbc.M909868199","article-title":"Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function","volume":"275","author":"Jiang","year":"2000","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib8","doi-asserted-by":"crossref","first-page":"7170","DOI":"10.1074\/jbc.M411058200","article-title":"The phosphatidylglycerol\/cardiolipin biosynthetic pathway is required for the activation of inositol phosphosphingolipid phospholipase C, Isc1p, during growth of Saccharomyces cerevisiae","volume":"280","author":"Vaena de Avalos","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib9","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1074\/jbc.M113.525733","article-title":"Unremodeled and remodeled cardiolipin are functionally indistinguishable in yeast","volume":"289","author":"Baile","year":"2014","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib10","doi-asserted-by":"crossref","first-page":"C33","DOI":"10.1152\/ajpcell.00243.2006","article-title":"Role of cardiolipin alterations in mitochondrial dysfunction and disease","volume":"292","author":"Chicco","year":"2007","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.jbc.2021.101462_bib11","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.tibs.2011.09.003","article-title":"The complexity of cardiolipin in health and disease","volume":"37","author":"Claypool","year":"2012","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.jbc.2021.101462_bib12","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1006\/bbrc.2000.3952","article-title":"Defective remodeling of cardiolipin and phosphatidylglycerol in Barth syndrome","volume":"279","author":"Vreken","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jbc.2021.101462_bib13","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1046\/j.1365-2958.2003.03802.x","article-title":"Aberrant cardiolipin metabolism in the yeast taz1 mutant: A model for Barth syndrome","volume":"51","author":"Gu","year":"2004","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jbc.2021.101462_bib14","doi-asserted-by":"crossref","first-page":"44394","DOI":"10.1074\/jbc.M405479200","article-title":"The human TAZ gene complements mitochondrial dysfunction in the yeast taz1Delta mutant. Implications for Barth syndrome","volume":"279","author":"Ma","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib15","doi-asserted-by":"crossref","first-page":"17107","DOI":"10.1074\/jbc.M800868200","article-title":"Yeast Pgc1p (YPL206c) controls the amount of phosphatidylglycerol via a phospholipase C-type degradation mechanism","volume":"283","author":"Simockov\u00e1","year":"2008","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib16","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.bbabio.2015.10.004","article-title":"Specific degradation of phosphatidylglycerol is necessary for proper mitochondrial morphology and function","volume":"1857","author":"Pokorn\u00e1","year":"2016","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jbc.2021.101462_bib17","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/1873-3468.12948","article-title":"Inactivation of cardiolipin synthase triggers changes in mitochondrial morphology","volume":"592","author":"Matsumura","year":"2018","journal-title":"FEBS Lett."},{"key":"10.1016\/j.jbc.2021.101462_bib18","doi-asserted-by":"crossref","DOI":"10.1093\/femsyr\/foz045","article-title":"The lipid droplet protein Pgc1 controls the subcellular distribution of phosphatidylglycerol","volume":"19","author":"Kubalov\u00e1","year":"2019","journal-title":"FEMS Yeast Res."},{"key":"10.1016\/j.jbc.2021.101462_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0182534","article-title":"MCK1 is a novel regulator of myo-inositol phosphate synthase (MIPS) that is required for inhibition of inositol synthesis by the mood stabilizer valproate","volume":"12","author":"Yu","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jbc.2021.101462_bib20","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1046\/j.1365-2958.2003.03641.x","article-title":"Valproate disrupts regulation of inositol responsive genes and alters regulation of phospholipid biosynthesis","volume":"49","author":"Ju","year":"2003","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jbc.2021.101462_bib21","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1093\/hmg\/ddw046","article-title":"Defining functional classes of Barth syndrome mutation in humans","volume":"25","author":"Lu","year":"2016","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.jbc.2021.101462_bib22","doi-asserted-by":"crossref","first-page":"33978","DOI":"10.1074\/jbc.M305242200","article-title":"Regulation of phosphatidylglycerophosphate synthase by inositol in Saccharomyces cerevisiae is not at the level of PGS1 mRNA abundance","volume":"278","author":"Zhong","year":"2003","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib23","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1111\/j.1365-2958.2004.04202.x","article-title":"Post-translational regulation of phosphatidylglycerolphosphate synthase in response to inositol","volume":"53","author":"He","year":"2004","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.jbc.2021.101462_bib24","doi-asserted-by":"crossref","first-page":"e337","DOI":"10.1542\/peds.2005-2667","article-title":"Cardiac and clinical phenotype in Barth syndrome","volume":"118","author":"Spencer","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.jbc.2021.101462_bib25","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1139\/O09-186","article-title":"Reduction in cholesterol synthesis in response to serum starvation in lymphoblasts of a patient with Barth syndrome","volume":"88","author":"Hauff","year":"2010","journal-title":"Biochem. Cell Biol."},{"key":"10.1016\/j.jbc.2021.101462_bib26","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/labinvest.3700274","article-title":"Characterization of lymphoblast mitochondria from patients with Barth syndrome","volume":"85","author":"Xu","year":"2005","journal-title":"Lab. Invest."},{"key":"10.1016\/j.jbc.2021.101462_bib27","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1750-1172-8-23","article-title":"Barth syndrome","volume":"8","author":"Clarke","year":"2013","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.jbc.2021.101462_bib28","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.bbadis.2013.03.005","article-title":"Barth syndrome: Cellular compensation of mitochondrial dysfunction and apoptosis inhibition due to changes in cardiolipin remodeling linked to tafazzin (TAZ) gene mutation","volume":"1832","author":"Gonzalvez","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jbc.2021.101462_bib29","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.bbalip.2012.11.007","article-title":"Cardiolipin remodeling and the function of tafazzin","volume":"1831","author":"Schlame","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jbc.2021.101462_bib30","doi-asserted-by":"crossref","first-page":"5143","DOI":"10.1091\/mbc.e08-09-0896","article-title":"The cardiolipin transacylase, tafazzin, associates with two distinct respiratory components providing insight into Barth syndrome","volume":"19","author":"Claypool","year":"2008","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.jbc.2021.101462_bib31","doi-asserted-by":"crossref","first-page":"32294","DOI":"10.1074\/jbc.M403275200","article-title":"Absence of cardiolipin results in temperature sensitivity, respiratory defects, and mitochondrial DNA instability independent of pet56","volume":"279","author":"Zhong","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib32","doi-asserted-by":"crossref","first-page":"35204","DOI":"10.1074\/jbc.M306729200","article-title":"Cardiolipin is not required to maintain mitochondrial DNA stability or cell viability for Saccharomyces cerevisiae grown at elevated temperatures","volume":"278","author":"Zhang","year":"2003","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib33","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S0006-8993(00)02797-9","article-title":"Chronic lithium and sodium valproate both decrease the concentration of myo-inositol and increase the concentration of inositol monophosphates in rat brain","volume":"880","author":"O\u2019Donnell","year":"2000","journal-title":"Brain Res."},{"key":"10.1016\/j.jbc.2021.101462_bib34","doi-asserted-by":"crossref","first-page":"15466","DOI":"10.1074\/jbc.M004179200","article-title":"Lithium and valproate decrease inositol mass and increase expression of the yeast INO1 and INO2 genes for inositol biosynthesis","volume":"276","author":"Vaden","year":"2001","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib35","doi-asserted-by":"crossref","first-page":"17589","DOI":"10.1074\/jbc.M111.330167","article-title":"Cardiolipin and mitochondrial phosphatidylethanolamine have overlapping functions in mitochondrial fusion in Saccharomyces cerevisiae","volume":"287","author":"Joshi","year":"2012","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib36","doi-asserted-by":"crossref","first-page":"35410","DOI":"10.1074\/jbc.M505478200","article-title":"Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in Saccharomyces cerevisiae","volume":"280","author":"Gohil","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib37","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/ana.10176","article-title":"Deficiency of tetralinoleoyl-cardiolipin in Barth syndrome","volume":"51","author":"Schlame","year":"2002","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jbc.2021.101462_bib38","doi-asserted-by":"crossref","first-page":"6161","DOI":"10.1021\/acs.jpcb.9b03413","article-title":"Ergosterol-induced ordered phase in ternary lipid mixture systems of unsaturated and saturated phospholipid membranes","volume":"123","author":"Bui","year":"2019","journal-title":"J.\u00a0Phys. Chem. B"},{"key":"10.1016\/j.jbc.2021.101462_bib39","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0022-510X(83)90209-5","article-title":"An X-linked mitochondrial disease affecting cardiac muscle, skeletal muscle and neutrophil leucocytes","volume":"62","author":"Barth","year":"1983","journal-title":"J.\u00a0Neurol. Sci."},{"key":"10.1016\/j.jbc.2021.101462_bib40","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/S0022-3476(05)80289-6","article-title":"X-linked dilated cardiomyopathy with neutropenia, growth retardation, and 3-methylglutaconic aciduria","volume":"119","author":"Kelley","year":"1991","journal-title":"J.\u00a0Pediatr."},{"key":"10.1016\/j.jbc.2021.101462_bib41","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1007\/s00431-011-1576-5","article-title":"Barth syndrome diagnosed in the subclinical stage of heart failure based on the presence of lipid storage myopathy and isolated noncompaction of the ventricular myocardium","volume":"170","author":"Takeda","year":"2011","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.jbc.2021.101462_bib42","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/labinvest.3700480","article-title":"Comparison of lymphoblast mitochondria from normal subjects and patients with Barth syndrome using electron microscopic tomography","volume":"87","author":"Acehan","year":"2007","journal-title":"Lab. Invest."},{"key":"10.1016\/j.jbc.2021.101462_bib43","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.bbamcr.2006.04.006","article-title":"Structure and dynamics of the mitochondrial inner membrane cristae","volume":"1763","author":"Mannella","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jbc.2021.101462_bib44","first-page":"439","article-title":"Overexpression of mitochondrial oxodicarboxylate carrier (ODC1) preserves oxidative phosphorylation in a yeast model of Barth syndrome","volume":"10","author":"de Taffin de Tilques","year":"2017","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.jbc.2021.101462_bib45","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1093\/emboj\/21.3.221","article-title":"The ATP synthase is involved in generating mitochondrial cristae morphology","volume":"21","author":"Paumard","year":"2002","journal-title":"EMBO J."},{"key":"10.1016\/j.jbc.2021.101462_bib46","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1365-2125.2006.02709.x","article-title":"Effects of three cytochrome P450 inhibitors, ketoconazole, fluconazole, and paroxetine, on the pharmacokinetics of lasofoxifene","volume":"63","author":"Ouellet","year":"2007","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jbc.2021.101462_bib47","doi-asserted-by":"crossref","first-page":"544","DOI":"10.3760\/cma.j.issn.0366-6999.2010.05.007","article-title":"Relationship between antifungal resistance of fluconazole resistant Candida albicans and mutations in ERG11 gene","volume":"123","author":"Feng","year":"2010","journal-title":"Chin. Med. J. (Engl.)"},{"key":"10.1016\/j.jbc.2021.101462_bib48","doi-asserted-by":"crossref","first-page":"651","DOI":"10.2174\/1389200215666141125121511","article-title":"Drug interactions between nine antifungal agents and drugs metabolized by human cytochromes P450","volume":"15","author":"Niwa","year":"2014","journal-title":"Curr. Drug Metab."},{"key":"10.1016\/j.jbc.2021.101462_bib49","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1046\/j.0306-5251.2001.01474.x","article-title":"In\u00a0vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: Preferential inhibition of cytochrome P450 2C9 (CYP2C9)","volume":"52","author":"Wen","year":"2001","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jbc.2021.101462_bib50","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1742-7843.2007.00061.x","article-title":"Inhibitory effect of valproic acid on cytochrome P450 2C9 activity in epilepsy patients","volume":"100","author":"Gunes","year":"2007","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"key":"10.1016\/j.jbc.2021.101462_bib51","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/0960-0760(92)90339-K","article-title":"Cytochrome P450 lanosterol 14\u03b1-demethylase (CYP51): Insights from molecular genetic analysis of the ERG11 gene in Saccharomyces cerevisiae","volume":"43","author":"Loper","year":"1992","journal-title":"J.\u00a0Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.jbc.2021.101462_bib52","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.3389\/fmicb.2017.01956","article-title":"pH-dependant antifungal activity of valproic acid against the human fungal pathogen Candida albicans","volume":"8","author":"Chaillot","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jbc.2021.101462_bib53","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/1567-1364.12107","article-title":"Squalene epoxidase as a target for manipulation of squalene levels in the yeast Saccharomyces cerevisiae","volume":"14","author":"Garaiov\u00e1","year":"2014","journal-title":"FEMS Yeast Res."},{"key":"10.1016\/j.jbc.2021.101462_bib54","doi-asserted-by":"crossref","first-page":"25692","DOI":"10.1074\/jbc.271.41.25692","article-title":"The role of phosphatidylcholine biosynthesis in the regulation of the INO1 gene of yeast","volume":"271","author":"Griac","year":"1996","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2021.101462_bib55","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1002\/yea.1018","article-title":"New \u2018marker swap\u2019 plasmids for converting selectable markers on budding yeast gene disruptions and plasmids","volume":"20","author":"Voth","year":"2003","journal-title":"Yeast"},{"key":"10.1016\/j.jbc.2021.101462_bib56","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0076-6879(02)50957-5","article-title":"Transformation of yeast by lithium acetate\/single-stranded carrier DNA\/polyethylene glycol method","volume":"350","author":"Gietz","year":"2002","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.jbc.2021.101462_bib57","doi-asserted-by":"crossref","first-page":"2887","DOI":"10.1242\/jcs.051227","article-title":"Furrow-like invaginations of the yeast plasma membrane correspond to membrane compartment of Can1","volume":"122","author":"Str\u00e1dalov\u00e1","year":"2009","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.jbc.2021.101462_bib58","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1139\/m83-222","article-title":"Phosphatidylglycerophosphate synthase activity in Saccharomyces cerevisiae","volume":"29","author":"Carman","year":"1983","journal-title":"Can. J. Microbiol."},{"key":"10.1016\/j.jbc.2021.101462_bib59","series-title":"Vaccine Adjuvants: Methods and Protocols","first-page":"95","article-title":"Biosynthetic approaches to squalene production: The case of yeast","author":"Valachovi\u010d","year":"2017"},{"key":"10.1016\/j.jbc.2021.101462_bib60","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/yea.2956","article-title":"The yeast Saccharomyces cerevisiae Pdr16p restricts changes in ergosterol biosynthesis caused by the presence of azole antifungals","volume":"30","author":"\u0160imov\u00e1","year":"2013","journal-title":"Yeast"},{"key":"10.1016\/j.jbc.2021.101462_bib61","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1016\/j.bbalip.2014.07.014","article-title":"Phosphatidylinositol binding of Saccharomyces cerevisiae Pdr16p represents an essential feature of this lipid transfer protein to provide protection against azole antifungals","volume":"1841","author":"Holi\u010d","year":"2014","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925821012710?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925821012710?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T06:27:15Z","timestamp":1778653635000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925821012710"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":61,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["S0021925821012710"],"URL":"https:\/\/doi.org\/10.1016\/j.jbc.2021.101462","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Blocking phosphatidylglycerol degradation in yeast defective in cardiolipin remodeling results in a new model of the Barth syndrome cellular phenotype","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jbc.2021.101462","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}],"article-number":"101462"}}