{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:34:57Z","timestamp":1791905697678,"version":"4.3.4"},"reference-count":50,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T00:00:00Z","timestamp":1683072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017962","name":"Jiangsu Commission of Health","doi-asserted-by":"publisher","award":["M2020060"],"award-info":[{"award-number":["M2020060"]}],"id":[{"id":"10.13039\/100017962","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2021YFC2700600"],"award-info":[{"award-number":["2021YFC2700600"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31530047"],"award-info":[{"award-number":["31530047"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81801515"],"award-info":[{"award-number":["81801515"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81902836"],"award-info":[{"award-number":["81902836"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82221005"],"award-info":[{"award-number":["82221005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["92168104"],"award-info":[{"award-number":["92168104"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.jbc.2023.104783","type":"journal-article","created":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T20:46:35Z","timestamp":1683146795000},"page":"104783","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner"],"prefix":"10.1016","volume":"299","author":[{"given":"Yifei","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jincheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenmeijie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjuan","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunfeng","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6499-7899","authenticated-orcid":false,"given":"Mingxi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yayun","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boxian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueqiu","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8277-5234","authenticated-orcid":false,"given":"Zhibin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbc.2023.104783_bib1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0140-6736(20)32667-2","article-title":"Male infertility","volume":"397","author":"Agarwal","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.jbc.2023.104783_bib2","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.aju.2017.10.005","article-title":"Prediction of male infertility by the World Health Organization laboratory manual for assessment of semen analysis: a systematic review","volume":"16","author":"Patel","year":"2018","journal-title":"Arab J. Urol."},{"key":"10.1016\/j.jbc.2023.104783_bib3","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.clinbiochem.2018.03.012","article-title":"Fertility and infertility: definition and epidemiology","volume":"62","author":"Vander Borght","year":"2018","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.jbc.2023.104783_bib4","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/s41580-019-0168-5","article-title":"Reading, writing and erasing mRNA methylation","volume":"20","author":"Zaccara","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2023.104783_bib5","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nrm.2016.132","article-title":"Post-transcriptional gene regulation by mRNA modifications","volume":"18","author":"Zhao","year":"2017","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2023.104783_bib6","doi-asserted-by":"crossref","DOI":"10.1093\/molehr\/gaab020","article-title":"RNA N6-methyladenosine modification, spermatogenesis, and human male infertility","volume":"27","author":"Cai","year":"2021","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.jbc.2023.104783_bib7","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.bbagrm.2018.10.016","article-title":"m(6)A mRNA modification regulates mammalian spermatogenesis","volume":"1862","author":"Lin","year":"2019","journal-title":"Biochim. Biophys. Acta Gene Regul. Mech."},{"key":"10.1016\/j.jbc.2023.104783_bib8","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.819044","article-title":"Genetic regulation of N6-methyladenosine-RNA in mammalian gametogenesis and embryonic development","volume":"10","author":"Chang","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.jbc.2023.104783_bib9","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1038\/cr.2017.117","article-title":"Mettl3-\/Mettl14-mediated mRNA N(6)-methyladenosine modulates murine spermatogenesis","volume":"27","author":"Lin","year":"2017","journal-title":"Cell Res."},{"key":"10.1016\/j.jbc.2023.104783_bib10","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1038\/cr.2017.100","article-title":"Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation","volume":"27","author":"Xu","year":"2017","journal-title":"Cell Res."},{"key":"10.1016\/j.jbc.2023.104783_bib11","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.molcel.2017.09.021","article-title":"Regulation of m(6)A transcripts by the 3'-->5' RNA Helicase YTHDC2 is essential for a Successful meiotic Program in the mammalian germline","volume":"68","author":"Wojtas","year":"2017","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jbc.2023.104783_bib12","doi-asserted-by":"crossref","first-page":"110110","DOI":"10.1016\/j.celrep.2021.110110","article-title":"YTHDC2 is essential for pachytene progression and prevents aberrant microtubule-driven telomere clustering in male meiosis","volume":"37","author":"Liu","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.jbc.2023.104783_bib13","doi-asserted-by":"crossref","first-page":"E325","DOI":"10.1073\/pnas.1717794115","article-title":"ALKBH5-dependent m6A demethylation controls splicing and stability of long 3'-UTR mRNAs in male germ cells","volume":"115","author":"Tang","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2023.104783_bib14","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.molcel.2012.10.015","article-title":"ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility","volume":"49","author":"Zheng","year":"2013","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jbc.2023.104783_bib15","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/nchembio.687","article-title":"N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO","volume":"7","author":"Jia","year":"2011","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.jbc.2023.104783_bib16","first-page":"1","article-title":"The role of m6A modification in the biological functions and diseases","volume":"6","author":"Jiang","year":"2021","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.jbc.2023.104783_bib17","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1056\/NEJMoa0803839","article-title":"An obesity-associated FTO gene variant and increased energy intake in children","volume":"359","author":"Cecil","year":"2008","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.jbc.2023.104783_bib18","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1038\/ng.713","article-title":"Overexpression of Fto leads to increased food intake and results in obesity","volume":"42","author":"Church","year":"2010","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jbc.2023.104783_bib19","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1038\/nature07848","article-title":"Inactivation of the Fto gene protects from obesity","volume":"458","author":"Fischer","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2023.104783_bib20","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.ajhg.2009.06.002","article-title":"Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations","volume":"85","author":"Boissel","year":"2009","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jbc.2023.104783_bib21","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1093\/hmg\/ddx128","article-title":"Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis","volume":"26","author":"Li","year":"2017","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.jbc.2023.104783_bib22","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1161\/CIRCULATIONAHA.118.033794","article-title":"FTO-dependent N(6)-methyladenosine regulates cardiac function during remodeling and repair","volume":"139","author":"Mathiyalagan","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.jbc.2023.104783_bib23","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s12929-021-00734-6","article-title":"The m(6)A epitranscriptome on neural development and degeneration","volume":"28","author":"Yen","year":"2021","journal-title":"J.\u00a0Biomed. Sci."},{"key":"10.1016\/j.jbc.2023.104783_bib24","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1126\/science.abe9582","article-title":"FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development","volume":"376","author":"Wei","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.jbc.2023.104783_bib25","doi-asserted-by":"crossref","first-page":"732","DOI":"10.3389\/fgene.2018.00732","article-title":"FTO knockout causes chromosome Instability and G2\/M arrest in mouse GC-1 cells","volume":"9","author":"Huang","year":"2018","journal-title":"Front. Genet."},{"key":"10.1016\/j.jbc.2023.104783_bib26","first-page":"1","article-title":"Meclofenamic acid represses spermatogonial proliferation through modulating m6A RNA modification","volume":"10","author":"Huang","year":"2019","journal-title":"J.\u00a0Anim. Sci. Biotechnol."},{"key":"10.1016\/j.jbc.2023.104783_bib27","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1095\/biolreprod.113.108597","article-title":"JMJD1C, a JmjC domain-containing protein, is required for long-term maintenance of male germ cells in mice","volume":"89","author":"Kuroki","year":"2013","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.jbc.2023.104783_bib28","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1002\/j.1939-4640.2002.tb02345.x","article-title":"Localization of androgen and estrogen receptors in adult male mouse reproductive tract","volume":"23","author":"Zhou","year":"2002","journal-title":"J.\u00a0Androl."},{"key":"10.1016\/j.jbc.2023.104783_bib29","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1096\/fj.14-255729","article-title":"Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset Leydig cell apoptosis in both mice and men","volume":"29","author":"O\u2019Hara","year":"2015","journal-title":"FASEB J."},{"key":"10.1016\/j.jbc.2023.104783_bib30","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.beem.2015.04.006","article-title":"Androgen receptor roles in spermatogenesis and infertility","volume":"29","author":"O'Hara","year":"2015","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.jbc.2023.104783_bib31","doi-asserted-by":"crossref","first-page":"7055","DOI":"10.1002\/jcp.26507","article-title":"Increased N6-methyladenosine causes infertility is associated with FTO expression","volume":"233","author":"Ding","year":"2018","journal-title":"J.\u00a0Cell. Physiol."},{"key":"10.1016\/j.jbc.2023.104783_bib32","doi-asserted-by":"crossref","first-page":"13498","DOI":"10.1073\/pnas.212474399","article-title":"Generation and characterization of androgen receptor knockout (ARKO) mice: an in\u00a0vivo model for the study of androgen functions in selective tissues","volume":"99","author":"Yeh","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2023.104783_bib33","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1677\/jme.1.01884","article-title":"Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model","volume":"35","author":"Notini","year":"2005","journal-title":"J.\u00a0Mol. Endocrinol."},{"key":"10.1016\/j.jbc.2023.104783_bib34","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1095\/biolreprod.113.108969","article-title":"INSL3 as a biomarker of Leydig cell functionality","volume":"88","author":"Ivell","year":"2013","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.jbc.2023.104783_bib35","doi-asserted-by":"crossref","first-page":"R89","DOI":"10.1530\/REP-20-0633","article-title":"Healthy ageing and spermatogenesis","volume":"161","author":"Pohl","year":"2021","journal-title":"Reproduction"},{"key":"10.1016\/j.jbc.2023.104783_bib36","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1007\/s11255-013-0610-0","article-title":"Quantitative histological analysis and ultrastructure of the aging human testis","volume":"46","author":"Jiang","year":"2014","journal-title":"Int. Urol. Nephrol."},{"key":"10.1016\/j.jbc.2023.104783_bib37","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/tcm.10085","article-title":"Effect of age on testicular germ cell apoptosis and sperm aneuploidy in MF-1 mice","volume":"23","author":"Brinkworth","year":"2003","journal-title":"Teratog. Carcinog. Mutagen."},{"key":"10.1016\/j.jbc.2023.104783_bib38","doi-asserted-by":"crossref","first-page":"R169","DOI":"10.1530\/REP-18-0476","article-title":"Molecular regulation of spermatogonial stem cell renewal and differentiation","volume":"158","author":"M\u00e4kel\u00e4","year":"2019","journal-title":"Reproduction"},{"key":"10.1016\/j.jbc.2023.104783_bib39","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.stem.2014.09.019","article-title":"m6A RNA modification controls cell fate transition in mammalian embryonic stem cells","volume":"15","author":"Batista","year":"2014","journal-title":"Cell stem cell"},{"key":"10.1016\/j.jbc.2023.104783_bib40","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/ncb2902","article-title":"N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells","volume":"16","author":"Wang","year":"2014","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.jbc.2023.104783_bib41","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1126\/science.aau1646","article-title":"RNA modifications modulate gene expression during development","volume":"361","author":"Frye","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.jbc.2023.104783_bib42","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2105192118","article-title":"N6-methyladenosine (m6A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells","volume":"118","author":"Jin","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2023.104783_bib43","doi-asserted-by":"crossref","first-page":"e1007412","DOI":"10.1371\/journal.pgen.1007412","article-title":"Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development","volume":"14","author":"Kasowitz","year":"2018","journal-title":"PLoS Genet."},{"key":"10.1016\/j.jbc.2023.104783_bib44","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1126\/science.aay6018","article-title":"N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription","volume":"367","author":"Liu","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.jbc.2023.104783_bib45","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1016\/j.apsb.2022.01.003","article-title":"Detailed resume of RNA m(6)A demethylases","volume":"12","author":"Shen","year":"2022","journal-title":"Acta Pharm. Sin B"},{"key":"10.1016\/j.jbc.2023.104783_bib46","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1038\/nature08921","article-title":"Crystal structure of the FTO protein reveals basis for its substrate specificity","volume":"464","author":"Han","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2023.104783_bib47","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ccell.2016.11.017","article-title":"FTO plays an oncogenic role in acute Myeloid leukemia as a N(6)-methyladenosine RNA demethylase","volume":"31","author":"Li","year":"2017","journal-title":"Cancer Cell"},{"key":"10.1016\/j.jbc.2023.104783_bib48","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.trecan.2022.02.010","article-title":"FTO in cancer: functions, molecular mechanisms, and therapeutic implications","volume":"8","author":"Li","year":"2022","journal-title":"Trends Cancer"},{"key":"10.1016\/j.jbc.2023.104783_bib49","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1016\/j.ajhg.2021.06.010","article-title":"Bi-allelic mutations of DNAH10 cause primary male infertility with asthenoteratozoospermia in humans and mice","volume":"108","author":"Tu","year":"2021","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jbc.2023.104783_bib50","first-page":"1","article-title":"Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella","volume":"10","author":"Shen","year":"2019","journal-title":"Nat. Commun."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925823018112?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925823018112?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T16:43:54Z","timestamp":1762188234000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925823018112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":50,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S0021925823018112"],"URL":"https:\/\/doi.org\/10.1016\/j.jbc.2023.104783","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jbc.2023.104783","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}],"article-number":"104783"}}