{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T04:54:50Z","timestamp":1785387290067,"version":"3.55.0"},"reference-count":124,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T00:00:00Z","timestamp":1698883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["F31HL165680"],"award-info":[{"award-number":["F31HL165680"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["F32 HL154387"],"award-info":[{"award-number":["F32 HL154387"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R00HL136695"],"award-info":[{"award-number":["R00HL136695"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL162595"],"award-info":[{"award-number":["R01HL162595"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL167778"],"award-info":[{"award-number":["R01HL167778"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["898429"],"award-info":[{"award-number":["898429"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.jbc.2023.105426","type":"journal-article","created":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T09:00:00Z","timestamp":1699002000000},"page":"105426","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Palmitoylation-dependent regulation of cardiomyocyte Rac1 signaling activity and minor effects on cardiac hypertrophy"],"prefix":"10.1016","volume":"299","author":[{"given":"Tanya A.","family":"Baldwin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5340-3290","authenticated-orcid":false,"given":"James P.","family":"Teuber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9493-9494","authenticated-orcid":false,"given":"Yasuhide","family":"Kuwabara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6563-6689","authenticated-orcid":false,"given":"Araskumar","family":"Subramani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4704-8576","authenticated-orcid":false,"given":"Suh-Chin J.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onur","family":"Kanisicak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8027-1809","authenticated-orcid":false,"given":"Ronald J.","family":"Vagnozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiqi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4904-7670","authenticated-orcid":false,"given":"Matthew J.","family":"Brody","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffery D.","family":"Molkentin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbc.2023.105426_bib1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/nrm3495","article-title":"Molecular basis of physiological heart growth: fundamental concepts and new players","volume":"14","author":"Maillet","year":"2013","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib2","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1172\/JCI62839","article-title":"Signaling effectors underlying pathologic growth and remodeling of the heart","volume":"123","author":"van Berlo","year":"2013","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.jbc.2023.105426_bib3","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/s41569-018-0007-y","article-title":"Mechanisms of physiological and pathological cardiac hypertrophy","volume":"15","author":"Nakamura","year":"2018","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.jbc.2023.105426_bib4","doi-asserted-by":"crossref","first-page":"337","DOI":"10.3389\/fphys.2016.00337","article-title":"The role of leucine-rich repeat containing protein 10 (LRRC10) in dilated cardiomyopathy","volume":"7","author":"Brody","year":"2016","journal-title":"Front Physiol."},{"key":"10.1016\/j.jbc.2023.105426_bib5","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1161\/CIRCULATIONAHA.112.109256","article-title":"G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure","volume":"126","author":"Takefuji","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jbc.2023.105426_bib6","doi-asserted-by":"crossref","first-page":"7432","DOI":"10.1073\/pnas.0510444103","article-title":"Requirement of Rac1 in the development of cardiac hypertrophy","volume":"103","author":"Satoh","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2023.105426_bib7","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1084\/jem.20122126","article-title":"RhoGEF12 controls cardiac remodeling by integrating G protein- and integrin-dependent signaling cascades","volume":"210","author":"Takefuji","year":"2013","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.jbc.2023.105426_bib8","doi-asserted-by":"crossref","first-page":"8121","DOI":"10.1073\/pnas.94.15.8121","article-title":"Transgenic Galphaq overexpression induces cardiac contractile failure in mice","volume":"94","author":"D'Angelo","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2023.105426_bib9","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1042\/bj3140115","article-title":"Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy","volume":"314","author":"Bogoyevitch","year":"1996","journal-title":"Biochem. J."},{"key":"10.1016\/j.jbc.2023.105426_bib10","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1172\/JCI6842","article-title":"Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure","volume":"103","author":"Sah","year":"1999","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.jbc.2023.105426_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/BJ20050104","article-title":"RhoGDI: multiple functions in the regulation of Rho family GTPase activities","volume":"390","author":"Dovas","year":"2005","journal-title":"Biochem. J."},{"key":"10.1016\/j.jbc.2023.105426_bib12","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/nrm3153","article-title":"The \u2018invisible hand\u2019: regulation of RHO GTPases by RHOGDIs","volume":"12","author":"Garcia-Mata","year":"2011","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib13","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/nature01148","article-title":"Rho GTPases in cell biology","volume":"420","author":"Etienne-Manneville","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2023.105426_bib14","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1038\/nrm.2016.67","article-title":"Regulating Rho GTPases and their regulators","volume":"17","author":"Hodge","year":"2016","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib15","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.molcel.2011.01.001","article-title":"FKBP12 binds to acylated H-ras and promotes depalmitoylation","volume":"41","author":"Ahearn","year":"2011","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jbc.2023.105426_bib16","doi-asserted-by":"crossref","first-page":"31141","DOI":"10.1074\/jbc.M504113200","article-title":"DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras","volume":"280","author":"Swarthout","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib17","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1038\/emboj.2011.446","article-title":"A\u00a0palmitoylation switch mechanism regulates Rac1 function and membrane organization","volume":"31","author":"Navarro-Lerida","year":"2012","journal-title":"EMBO J."},{"key":"10.1016\/j.jbc.2023.105426_bib18","doi-asserted-by":"crossref","first-page":"34448","DOI":"10.1074\/jbc.M111.273342","article-title":"Plasma membrane association of p63 Rho guanine nucleotide exchange factor (p63RhoGEF) is mediated by palmitoylation and is required for basal activity in cells","volume":"286","author":"Aittaleb","year":"2011","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib19","first-page":"195","article-title":"Analysis of RGS protein palmitoylation","volume":"237","author":"Bernstein","year":"2004","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib20","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1161\/01.RES.0000158287.49872.4e","article-title":"Multi-tasking RGS proteins in the heart: the next therapeutic target?","volume":"96","author":"Riddle","year":"2005","journal-title":"Circ. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib21","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1172\/JCI8497","article-title":"Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1","volume":"105","author":"Sussman","year":"2000","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.jbc.2023.105426_bib22","doi-asserted-by":"crossref","first-page":"3079","DOI":"10.1172\/JCI37694","article-title":"Cdc42 is an antihypertrophic molecular switch in the mouse heart","volume":"119","author":"Maillet","year":"2009","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.jbc.2023.105426_bib23","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1161\/01.CIR.0000091084.46500.BB","article-title":"Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment","volume":"108","author":"Maack","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jbc.2023.105426_bib24","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.2005262","article-title":"RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis","volume":"7","author":"Lauriol","year":"2014","journal-title":"Sci. Signal."},{"key":"10.1016\/j.jbc.2023.105426_bib25","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1161\/HYPERTENSIONAHA.115.06054","article-title":"Rac1-mediated activation of mineralocorticoid receptor in pressure overload-induced cardiac injury","volume":"67","author":"Ayuzawa","year":"2016","journal-title":"Hypertension"},{"key":"10.1016\/j.jbc.2023.105426_bib26","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1126\/science.1660188","article-title":"Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2","volume":"254","author":"Knaus","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.jbc.2023.105426_bib27","doi-asserted-by":"crossref","first-page":"25051","DOI":"10.1074\/jbc.274.35.25051","article-title":"Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidase","volume":"274","author":"Koga","year":"1999","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib28","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.3390\/antiox11091822","article-title":"NADPH oxidases in diastolic dysfunction and heart failure with preserved ejection fraction","volume":"11","author":"Teuber","year":"2022","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.jbc.2023.105426_bib29","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1172\/JCI13350","article-title":"Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy","volume":"108","author":"Takemoto","year":"2001","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.jbc.2023.105426_bib30","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/01.mca.0000130229.18685.b9","article-title":"Statins and myocardial hypertrophy","volume":"15","author":"Nakagami","year":"2004","journal-title":"Coron. Artery Dis."},{"key":"10.1016\/j.jbc.2023.105426_bib31","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/nmeth.1769","article-title":"Global profiling of dynamic protein palmitoylation","volume":"9","author":"Martin","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.jbc.2023.105426_bib32","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1021\/acschembio.8b00157","article-title":"Temporal profiling establishes a dynamic S-palmitoylation cycle","volume":"13","author":"Won","year":"2018","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib33","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.ejcb.2011.09.013","article-title":"Human DHHC proteins: a spotlight on the hidden player of palmitoylation","volume":"91","author":"Korycka","year":"2012","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib34","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.tibs.2011.01.003","article-title":"DHHC palmitoyl transferases: substrate interactions and (patho)physiology","volume":"36","author":"Greaves","year":"2011","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.jbc.2023.105426_bib35","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1042\/BST20160304","article-title":"Structure and function of DHHC protein S-acyltransferases","volume":"45","author":"Gottlieb","year":"2017","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.jbc.2023.105426_bib36","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/nrm2084","article-title":"Palmitoylation: policing protein stability and traffic","volume":"8","author":"Linder","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib37","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.11306","article-title":"ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization","volume":"4","author":"Lin","year":"2015","journal-title":"Elife"},{"key":"10.1016\/j.jbc.2023.105426_bib38","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.bbalip.2006.03.010","article-title":"Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins","volume":"1761","author":"Ohno","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jbc.2023.105426_bib39","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1007\/s00424-008-0465-x","article-title":"Discovery of protein-palmitoylating enzymes","volume":"456","author":"Tsutsumi","year":"2008","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.jbc.2023.105426_bib40","doi-asserted-by":"crossref","first-page":"17534","DOI":"10.1073\/pnas.1413627111","article-title":"Substrate recognition by the cell surface palmitoyl transferase DHHC5","volume":"111","author":"Howie","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2023.105426_bib41","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.neuron.2004.12.005","article-title":"Identification of PSD-95 palmitoylating enzymes","volume":"44","author":"Fukata","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.jbc.2023.105426_bib42","doi-asserted-by":"crossref","first-page":"3870","DOI":"10.1091\/mbc.e14-06-1169","article-title":"The Golgi S-acylation machinery comprises zDHHC enzymes with major differences in substrate affinity and S-acylation activity","volume":"25","author":"Lemonidis","year":"2014","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.jbc.2023.105426_bib43","doi-asserted-by":"crossref","first-page":"108","DOI":"10.3389\/fphys.2020.00108","article-title":"Palmitoylation: a fatty regulator of myocardial electrophysiology","volume":"11","author":"Essandoh","year":"2020","journal-title":"Front Physiol."},{"key":"10.1016\/j.jbc.2023.105426_bib44","doi-asserted-by":"crossref","first-page":"5881","DOI":"10.1523\/JNEUROSCI.1037-04.2004","article-title":"The gamma2 subunit of GABA(A) receptors is a substrate for palmitoylation by GODZ","volume":"24","author":"Keller","year":"2004","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.jbc.2023.105426_bib45","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.neuron.2005.06.035","article-title":"Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites","volume":"47","author":"Hayashi","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.jbc.2023.105426_bib46","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.neuron.2009.08.017","article-title":"Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking","volume":"64","author":"Hayashi","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/j.jbc.2023.105426_bib47","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.aar4394","article-title":"Palmitoylation of delta-catenin promotes kinesin-mediated membrane trafficking of Nav1.6 in sensory neurons to promote neuropathic pain","volume":"11","author":"Zhang","year":"2018","journal-title":"Sci. Signal."},{"key":"10.1016\/j.jbc.2023.105426_bib48","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/s44161-022-00028-6","article-title":"Single-cell transcriptomics reveals cell-type-specific diversification in human heart failure","volume":"1","author":"Koenig","year":"2022","journal-title":"Nat. Cardiovasc. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib49","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms12260","article-title":"Genetic lineage tracing defines myofibroblast origin and function in the injured heart","volume":"7","author":"Kanisicak","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jbc.2023.105426_bib50","doi-asserted-by":"crossref","first-page":"4435","DOI":"10.1038\/s41467-018-06639-7","article-title":"Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure","volume":"9","author":"Nomura","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jbc.2023.105426_bib51","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1161\/01.RES.0000065442.64694.9F","article-title":"Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoter","volume":"92","author":"Sanbe","year":"2003","journal-title":"Circ. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib52","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1161\/CIRCRESAHA.111.262717","article-title":"Lost in transgenesis: a user's guide for genetically manipulating the mouse in cardiac research","volume":"111","author":"Davis","year":"2012","journal-title":"Circ. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib53","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/978-3-319-06068-2_5","article-title":"Stable isotope labeling by amino acids in cell culture (SILAC) for quantitative proteomics","volume":"806","author":"Hoedt","year":"2014","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib54","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1194\/jlr.D011106","article-title":"Site-specific analysis of protein S-acylation by resin-assisted capture","volume":"52","author":"Forrester","year":"2011","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.jbc.2023.105426_bib55","doi-asserted-by":"crossref","first-page":"9994","DOI":"10.1074\/jbc.M900724200","article-title":"Palmitoylation controls the catalytic activity and subcellular distribution of phosphatidylinositol 4-kinase II{alpha}","volume":"284","author":"Barylko","year":"2009","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib56","doi-asserted-by":"crossref","first-page":"21856","DOI":"10.1074\/jbc.M112.348094","article-title":"Phosphatidylinositol 4-kinase IIalpha is palmitoylated by Golgi-localized palmitoyltransferases in cholesterol-dependent manner","volume":"287","author":"Lu","year":"2012","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib57","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.bbamcr.2015.02.002","article-title":"Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation","volume":"1853","author":"Kwon","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jbc.2023.105426_bib58","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/nchembio.2119","article-title":"ZDHHC7-mediated S-palmitoylation of scribble regulates cell polarity","volume":"12","author":"Chen","year":"2016","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib59","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1004405","article-title":"Curation of the mammalian palmitoylome indicates a pivotal role for palmitoylation in diseases and disorders of the nervous system and cancers","volume":"11","author":"Sanders","year":"2015","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib60","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1128\/MCB.01144-08","article-title":"Identification of G protein alpha subunit-palmitoylating enzyme","volume":"29","author":"Tsutsumi","year":"2009","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib61","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1021\/acs.chemrev.6b00750","article-title":"Protein Lipidation: occurrence, mechanisms, biological functions, and enabling technologies","volume":"118","author":"Jiang","year":"2018","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jbc.2023.105426_bib62","doi-asserted-by":"crossref","first-page":"21512","DOI":"10.1074\/jbc.273.34.21512","article-title":"Structural requirements for PAK activation by Rac GTPases","volume":"273","author":"Knaus","year":"1998","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib63","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/ncb2972","article-title":"A\u00a0Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly","volume":"16","author":"Moshfegh","year":"2014","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib64","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1038\/sj.onc.1205302","article-title":"PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway","volume":"21","author":"Coles","year":"2002","journal-title":"Oncogene"},{"key":"10.1016\/j.jbc.2023.105426_bib65","doi-asserted-by":"crossref","first-page":"20093","DOI":"10.1074\/jbc.M112.426023","article-title":"p21-activated kinase 1 (PAK1) can promote ERK activation in a kinase-independent manner","volume":"288","author":"Wang","year":"2013","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib66","doi-asserted-by":"crossref","first-page":"3729","DOI":"10.1242\/jcs.027680","article-title":"PAK1-mediated activation of ERK1\/2 regulates lamellipodial dynamics","volume":"121","author":"Smith","year":"2008","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.jbc.2023.105426_bib67","doi-asserted-by":"crossref","first-page":"6341","DOI":"10.1093\/emboj\/19.23.6341","article-title":"The MEK1-ERK1\/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice","volume":"19","author":"Bueno","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/j.jbc.2023.105426_bib68","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1161\/CIRCRESAHA.110.231514","article-title":"Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth","volume":"108","author":"Kehat","year":"2011","journal-title":"Circ. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib69","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1161\/01.RES.0000038488.38975.1A","article-title":"Involvement of extracellular signal-regulated kinases 1\/2 in cardiac hypertrophy and cell death","volume":"91","author":"Bueno","year":"2002","journal-title":"Circ. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib70","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/ncb2049","article-title":"Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1","volume":"12","author":"Boulter","year":"2010","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib71","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1161\/01.RES.0000216039.75913.9e","article-title":"The Rac and Rho hall of fame: a decade of hypertrophic signaling hits","volume":"98","author":"Brown","year":"2006","journal-title":"Circ. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib72","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1038\/nm1101-1236","article-title":"Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq\/Galpha11 in cardiomyocytes","volume":"7","author":"Wettschureck","year":"2001","journal-title":"Nat. Med."},{"key":"10.1016\/j.jbc.2023.105426_bib73","doi-asserted-by":"crossref","first-page":"3112","DOI":"10.1158\/0008-5472.CAN-04-0026","article-title":"Galectin-1(L11A) predicted from a computed galectin-1 farnesyl-binding pocket selectively inhibits Ras-GTP","volume":"64","author":"Rotblat","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.jbc.2023.105426_bib74","doi-asserted-by":"crossref","DOI":"10.1038\/srep32999","article-title":"Generation of self-clusters of galectin-1 in the farnesyl-bound form","volume":"6","author":"Yamaguchi","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jbc.2023.105426_bib75","doi-asserted-by":"crossref","first-page":"7486","DOI":"10.1038\/sj.onc.1204950","article-title":"Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation","volume":"20","author":"Paz","year":"2001","journal-title":"Oncogene"},{"key":"10.1016\/j.jbc.2023.105426_bib76","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1038\/s41467-019-08691-3","article-title":"Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads","volume":"10","author":"Chen","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jbc.2023.105426_bib77","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/nature23887","article-title":"Palmitoylation-dependent activation of MC1R prevents melanomagenesis","volume":"549","author":"Chen","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2023.105426_bib78","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.bbrc.2017.09.044","article-title":"Induced sensitivity to EGFR inhibitors is mediated by palmitoylated cysteine 1025 of EGFR and requires oncogenic Kras","volume":"493","author":"Kharbanda","year":"2017","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jbc.2023.105426_bib79","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.molcel.2016.04.003","article-title":"Inhibition of DHHC20-mediated EGFR palmitoylation creates a dependence on EGFR signaling","volume":"62","author":"Runkle","year":"2016","journal-title":"Mol. Cell"},{"key":"10.1016\/j.jbc.2023.105426_bib80","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.aax2364","article-title":"Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis","volume":"13","author":"Kharbanda","year":"2020","journal-title":"Sci. Signal."},{"key":"10.1016\/j.jbc.2023.105426_bib81","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1182\/blood.2019003530","article-title":"Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice","volume":"135","author":"Zambetti","year":"2020","journal-title":"Blood"},{"key":"10.1016\/j.jbc.2023.105426_bib82","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/s41586-020-2799-2","article-title":"A\u00a0STAT3 palmitoylation cycle promotes TH17 differentiation and colitis","volume":"586","author":"Zhang","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2023.105426_bib83","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/s41586-018-0287-8","article-title":"Targeting STING with covalent small-molecule inhibitors","volume":"559","author":"Haag","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2023.105426_bib84","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/s41423-019-0205-5","article-title":"STING palmitoylation as a therapeutic target Cell","volume":"16","author":"Hansen","year":"2019","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.jbc.2023.105426_bib85","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/s41587-019-0060-z","article-title":"Drug developers switch gears to inhibit STING","volume":"37","author":"Sheridan","year":"2019","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.jbc.2023.105426_bib86","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1161\/CIRCRESAHA.120.316752","article-title":"Endothelial palmitoylation cycling coordinates vessel remodeling in peripheral artery disease","volume":"127","author":"Wei","year":"2020","journal-title":"Circ. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib87","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.thromres.2009.07.005","article-title":"Palmitoylation supports the association of tetraspanin CD63 with CD9 and integrin alphaIIbbeta3 in activated platelets","volume":"125","author":"Israels","year":"2010","journal-title":"Thromb. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib88","doi-asserted-by":"crossref","first-page":"20232","DOI":"10.1074\/jbc.M116.725762","article-title":"S-palmitoylation of a novel site in the beta2-adrenergic receptor associated with a novel intracellular itinerary","volume":"291","author":"Adachi","year":"2016","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib89","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1161\/ATVBAHA.115.306942","article-title":"The protein acyl transferase ZDHHC21 modulates alpha1 adrenergic receptor function and regulates hemodynamics","volume":"36","author":"Marin","year":"2016","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib90","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/s42003-019-0482-7","article-title":"Crystal structure of human endothelin ETB receptor in complex with peptide inverse agonist IRL2500","volume":"2","author":"Nagiri","year":"2019","journal-title":"Commun. Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib91","doi-asserted-by":"crossref","first-page":"20811","DOI":"10.1074\/jbc.271.34.20811","article-title":"Palmitoylation of endothelin receptor A. Differential modulation of signal transduction activity by post-translational modification","volume":"271","author":"Horstmeyer","year":"1996","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib92","doi-asserted-by":"crossref","first-page":"5449","DOI":"10.1046\/j.0014-2956.2001.02486.x","article-title":"Coupling of endothelin receptors to the ERK\/MAP kinase pathway. Roles of palmitoylation and G(alpha)q","volume":"268","author":"Cramer","year":"2001","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.jbc.2023.105426_bib93","doi-asserted-by":"crossref","first-page":"25001","DOI":"10.1016\/S0021-9258(19)74563-3","article-title":"Palmitoylation is required for signaling functions and membrane attachment of Gq alpha and Gs alpha","volume":"268","author":"Wedegaertner","year":"1993","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib94","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.bpj.2019.08.018","article-title":"DHHC5 mediates beta-adrenergic signaling in cardiomyocytes by targeting Galpha proteins","volume":"118","author":"Chen","year":"2020","journal-title":"Biophys. J."},{"key":"10.1016\/j.jbc.2023.105426_bib95","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.jacbts.2022.11.003","article-title":"zDHHC9 regulates cardiomyocyte Rab3a activity and atrial natriuretic peptide secretion through palmitoylation of Rab3gap1","volume":"8","author":"Essandoh","year":"2023","journal-title":"JACC Basic Transl. Sci."},{"key":"10.1016\/j.jbc.2023.105426_bib96","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1172\/JCI2552","article-title":"A\u00a0requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy","volume":"102","author":"Pracyk","year":"1998","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.jbc.2023.105426_bib97","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1111\/jcmm.12840","article-title":"Inhibition of Rac1 reduces store overload-induced calcium release and protects against ventricular arrhythmia","volume":"20","author":"Zhang","year":"2016","journal-title":"J.\u00a0Cell Mol. Med."},{"key":"10.1016\/j.jbc.2023.105426_bib98","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1093\/cvr\/cvq079","article-title":"Cardiac Rac1 overexpression in mice creates a substrate for atrial arrhythmias characterized by structural remodelling","volume":"87","author":"Reil","year":"2010","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib99","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S0092-8674(02)00800-0","article-title":"Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170","volume":"109","author":"Fukata","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.jbc.2023.105426_bib100","doi-asserted-by":"crossref","first-page":"E267","DOI":"10.1073\/pnas.1409667112","article-title":"Single-molecule tracking of small GTPase Rac1 uncovers spatial regulation of membrane translocation and mechanism for polarized signaling","volume":"112","author":"Das","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2023.105426_bib101","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1093\/jb\/mvg149","article-title":"Structural basis of the Rho GTPase signaling","volume":"134","author":"Hakoshima","year":"2003","journal-title":"J.\u00a0Biochem."},{"key":"10.1016\/j.jbc.2023.105426_bib102","doi-asserted-by":"crossref","first-page":"25150","DOI":"10.1074\/jbc.M800882200","article-title":"Rho family GTPase modification and dependence on CAAX motif-signaled posttranslational modification","volume":"283","author":"Roberts","year":"2008","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib103","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1128\/MCB.01398-12","article-title":"Identification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI binding","volume":"33","author":"Nishimura","year":"2013","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib104","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/nrm.2015.11","article-title":"Protein prenylation: unique fats make their mark on biology","volume":"17","author":"Wang","year":"2016","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib105","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/S0008-6363(01)00540-5","article-title":"Impact of HMG CoA reductase inhibition on small GTPases in the heart","volume":"53","author":"Laufs","year":"2002","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib106","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s003950200000","article-title":"Pleiotropic effects of HMG-CoA reductase inhibitors","volume":"97","author":"Werner","year":"2002","journal-title":"Basic Res. Cardiol."},{"key":"10.1016\/j.jbc.2023.105426_bib107","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1161\/01.RES.0000196564.18314.23","article-title":"Rho GTPases, statins, and nitric oxide","volume":"97","author":"Rikitake","year":"2005","journal-title":"Circ. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib108","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1161\/01.RES.0000168040.70096.2a","article-title":"Statin-mediated inhibition of Rho: only to get more NO?","volume":"96","author":"Brandes","year":"2005","journal-title":"Circ. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib109","doi-asserted-by":"crossref","first-page":"24266","DOI":"10.1074\/jbc.273.37.24266","article-title":"Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase","volume":"273","author":"Laufs","year":"1998","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib110","doi-asserted-by":"crossref","first-page":"8918","DOI":"10.1074\/jbc.RA119.007585","article-title":"Disruption of valosin-containing protein activity causes cardiomyopathy and reveals pleiotropic functions in cardiac homeostasis","volume":"294","author":"Brody","year":"2019","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2023.105426_bib111","doi-asserted-by":"crossref","first-page":"e00114","DOI":"10.1128\/MCB.00114-18","article-title":"Defective Flux of thrombospondin-4 through the secretory pathway impairs cardiomyocyte membrane stability and causes cardiomyopathy","volume":"38","author":"Brody","year":"2018","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib112","article-title":"Nemo-like kinase (NLK) is a pathological signaling effector in the mouse heart","volume":"11","author":"Liu","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jbc.2023.105426_bib113","doi-asserted-by":"crossref","first-page":"5652","DOI":"10.4049\/jimmunol.170.11.5652","article-title":"Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions","volume":"170","author":"Glogauer","year":"2003","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.jbc.2023.105426_bib114","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1242\/dev.119.4.1229","article-title":"Normal development of mice carrying a null mutation in the gene encoding the L14 S-type lectin","volume":"119","author":"Poirier","year":"1993","journal-title":"Development"},{"key":"10.1016\/j.jbc.2023.105426_bib115","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1161\/01.RES.0000215985.18538.c4","article-title":"Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability","volume":"98","author":"Oka","year":"2006","journal-title":"Circ. Res."},{"key":"10.1016\/j.jbc.2023.105426_bib116","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1007\/s00429-019-01898-6","article-title":"Deficiency of the palmitoyl acyltransferase ZDHHC7 impacts brain and behavior of mice in a sex-specific manner","volume":"224","author":"Hohoff","year":"2019","journal-title":"Brain Struct. Funct."},{"key":"10.1016\/j.jbc.2023.105426_bib117","doi-asserted-by":"crossref","first-page":"23.16.1","DOI":"10.1002\/cpmb.9","article-title":"AAV9 delivery of shRNA to the mouse heart","volume":"115","author":"Wakimoto","year":"2016","journal-title":"Curr. Protoc. Mol. Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib118","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0051621","article-title":"Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy","volume":"7","author":"Brody","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jbc.2023.105426_bib119","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2023.1054169","article-title":"Rpl3l gene deletion in mice reduces heart weight over time","volume":"14","author":"Grimes","year":"2023","journal-title":"Front Physiol."},{"key":"10.1016\/j.jbc.2023.105426_bib120","doi-asserted-by":"crossref","first-page":"E4010","DOI":"10.1073\/pnas.1616393114","article-title":"Inducible Fgf13 ablation enhances caveolae-mediated cardioprotection during cardiac pressure overload","volume":"114","author":"Wei","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2023.105426_bib121","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1128\/MCB.00607-15","article-title":"Dissection of thrombospondin-4 domains involved in intracellular adaptive ER Stress responsive signaling","volume":"36","author":"Brody","year":"2015","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2023.105426_bib122","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aaw4597","article-title":"Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD","volume":"5","author":"Karch","year":"2019","journal-title":"Sci. Adv."},{"key":"10.1016\/j.jbc.2023.105426_bib123","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms10084","article-title":"MBNL1-mediated regulation of differentiation RNAs promotes myofibroblast transformation and the fibrotic response","volume":"6","author":"Davis","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jbc.2023.105426_bib124","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.cell.2006.03.042","article-title":"Global analysis of protein palmitoylation in yeast","volume":"125","author":"Roth","year":"2006","journal-title":"Cell"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925823024547?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925823024547?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:52:46Z","timestamp":1758243166000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925823024547"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":124,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S0021925823024547"],"URL":"https:\/\/doi.org\/10.1016\/j.jbc.2023.105426","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Palmitoylation-dependent regulation of cardiomyocyte Rac1 signaling activity and minor effects on cardiac hypertrophy","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jbc.2023.105426","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}],"article-number":"105426"}}