{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T06:42:03Z","timestamp":1792651323238,"version":"4.5.0"},"reference-count":68,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T00:00:00Z","timestamp":1710201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31872494"],"award-info":[{"award-number":["31872494"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.jbc.2024.107168","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T12:14:35Z","timestamp":1710332075000},"page":"107168","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Neuroinvasive virus facilitates viral replication by employing lipid droplets to reduce arachidonic acid-induced ferroptosis"],"prefix":"10.1016","volume":"300","author":[{"given":"Jianqing","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianruo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2011-3737","authenticated-orcid":false,"given":"Zhenkun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinquan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen F.","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0569-8105","authenticated-orcid":false,"given":"Ling","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbc.2024.107168_bib1","doi-asserted-by":"crossref","first-page":"4018","DOI":"10.3390\/ijms23074018","article-title":"Neurotropic RNA virus modulation of immune responses within the central nervous system","volume":"23","author":"Vazquez","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jbc.2024.107168_bib2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1146\/annurev-virology-092917-043439","article-title":"Flaviviruses and the central nervous system: revisiting neuropathological concepts","volume":"5","author":"Maximova","year":"2018","journal-title":"Annu. Rev. Virol."},{"key":"10.1016\/j.jbc.2024.107168_bib3","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1073\/pnas.0913351107","article-title":"Myelin-associated glycoprotein mediates membrane fusion and entry of neurotropic herpesviruses","volume":"107","author":"Suenaga","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2024.107168_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1010763","article-title":"TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection","volume":"18","author":"Yousefi","year":"2022","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jbc.2024.107168_bib5","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s12974-023-02736-7","article-title":"Metabolic reprogramming and lipid droplets are involved in Zika virus replication in neural cells","volume":"20","author":"Dias","year":"2023","journal-title":"J.\u00a0Neuroinflammation"},{"key":"10.1016\/j.jbc.2024.107168_bib6","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/s41580-018-0085-z","article-title":"Dynamics and functions of lipid droplets","volume":"20","author":"Olzmann","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib7","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1021\/acs.biochem.7b00975","article-title":"A\u00a0protective role for triacylglycerols during apoptosis","volume":"57","author":"Li","year":"2018","journal-title":"Biochemistry"},{"key":"10.1016\/j.jbc.2024.107168_bib8","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.ceb.2019.03.018","article-title":"Lipid droplet biogenesis","volume":"59","author":"Jackson","year":"2019","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib9","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.01473-21","article-title":"Lipid droplets are beneficial for rabies virus replication by facilitating viral budding","volume":"96","author":"Zhao","year":"2022","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jbc.2024.107168_bib10","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.lfs.2018.04.049","article-title":"Omega-3 and omega-6 polyunsaturated fatty acids: dietary sources, metabolism, and significance - a review","volume":"203","author":"Saini","year":"2018","journal-title":"Life Sci."},{"key":"10.1016\/j.jbc.2024.107168_bib11","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/0301-0082(95)00016-O","article-title":"Arachidonic acid as a neurotoxic and neurotrophic substance","volume":"46","author":"Katsuki","year":"1995","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.jbc.2024.107168_bib12","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1194\/jlr.R068072","article-title":"The discovery and early structural studies of arachidonic acid","volume":"57","author":"Martin","year":"2016","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.jbc.2024.107168_bib13","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1074\/jbc.M610067200","article-title":"Arachidonate-derived dihomoprostaglandin production observed in endotoxin-stimulated macrophage-like cells","volume":"282","author":"Harkewicz","year":"2007","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2024.107168_bib14","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.bbalip.2009.08.007","article-title":"Control of free arachidonic acid levels by phospholipases A2 and lysophospholipid acyltransferases","volume":"1791","author":"Perez-Chacon","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jbc.2024.107168_bib15","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.redox.2018.10.001","article-title":"Dihomo-gamma-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA","volume":"20","author":"Yang","year":"2019","journal-title":"Redox Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib16","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.3390\/ijms24032116","article-title":"Dihomo-\u03b3-Linolenic acid (20:3n-6)-metabolism, Derivatives, and potential significance in Chronic inflammation","volume":"24","author":"Mustonen","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jbc.2024.107168_bib17","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/s12944-019-1039-y","article-title":"Intake of arachidonic acid-containing lipids in adult humans: dietary surveys and clinical trials","volume":"18","author":"Kawashima","year":"2019","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.jbc.2024.107168_bib18","doi-asserted-by":"crossref","first-page":"216","DOI":"10.3390\/nu8040216","article-title":"The Essentiality of arachidonic acid in infant development","volume":"8","author":"Hadley","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.jbc.2024.107168_bib19","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.3390\/ijms18122661","article-title":"Arachidonic acid metabolite as a novel therapeutic target in breast cancer metastasis","volume":"18","author":"Borin","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jbc.2024.107168_bib20","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.bbrc.2022.03.089","article-title":"Arachidonic acid supplementation attenuates adipocyte inflammation but not adiposity in high fat diet induced obese mice","volume":"608","author":"Roy","year":"2022","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jbc.2024.107168_bib21","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.4049\/jimmunol.2100393","article-title":"Myeloid-specific deficiency of long-chain acyl CoA synthetase 4 reduces inflammation by Remodeling phospholipids and reducing production of arachidonic acid-derived Proinflammatory lipid mediators","volume":"207","author":"Reeves","year":"2021","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.jbc.2024.107168_bib22","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/nchembio.2238","article-title":"Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis","volume":"13","author":"Kagan","year":"2017","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib23","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1038\/s41467-020-15646-6","article-title":"Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease","volume":"11","author":"Mayr","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jbc.2024.107168_bib24","article-title":"Lipid droplets and lipid mediators in viral infection and immunity","volume":"45","author":"Monson","year":"2021","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.jbc.2024.107168_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2019.101328","article-title":"Insight into the mechanism of ferroptosis inhibition by ferrostatin-1","volume":"28","author":"Miotto","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102541","article-title":"Inhibition of ferroptosis promotes retina ganglion cell survival in experimental optic neuropathies","volume":"58","author":"Guo","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib27","article-title":"TRIM34 modulates influenza virus-activated programmed cell death by targeting Z-DNA-binding protein 1 for K63-linked polyubiquitination","volume":"298","author":"Wang","year":"2022","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2024.107168_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1010718","article-title":"Viral-mediated activation and inhibition of programmed cell death","volume":"18","author":"Verburg","year":"2022","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jbc.2024.107168_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2021.102837","article-title":"Newcastle-disease-virus-induced ferroptosis through nutrient deprivation and ferritinophagy in tumor cells","volume":"24","author":"Kan","year":"2021","journal-title":"iScience"},{"key":"10.1016\/j.jbc.2024.107168_bib30","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/s12985-022-01825-y","article-title":"Swine influenza virus triggers ferroptosis in A549 cells to enhance virus replication","volume":"19","author":"Cheng","year":"2022","journal-title":"Virol. J."},{"key":"10.1016\/j.jbc.2024.107168_bib31","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.chembiol.2021.07.022","article-title":"FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication","volume":"29","author":"Yamane","year":"2022","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib32","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.02717-21","article-title":"Acyl-coenzyme A synthetase long-chain family member 4 is involved in viral replication Organelle formation and facilitates virus replication via ferroptosis","volume":"13","author":"Kung","year":"2022","journal-title":"mBio"},{"key":"10.1016\/j.jbc.2024.107168_bib33","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.01209-23","article-title":"DHA and EPA inhibit porcine coronavirus replication by alleviating ER stress","volume":"97","author":"Suo","year":"2023","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jbc.2024.107168_bib34","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/s41422-020-00441-1","article-title":"Ferroptosis: molecular mechanisms and health implications","volume":"31","author":"Tang","year":"2021","journal-title":"Cell Res."},{"key":"10.1016\/j.jbc.2024.107168_bib35","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/nchembio.2239","article-title":"ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition","volume":"13","author":"Doll","year":"2017","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib36","doi-asserted-by":"crossref","first-page":"941","DOI":"10.3390\/cells8080941","article-title":"Neutral lipids are not a Source of arachidonic acid for lipid mediator signaling in human Foamy Monocytes","volume":"8","author":"Guijas","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.jbc.2024.107168_bib37","doi-asserted-by":"crossref","first-page":"2596","DOI":"10.1016\/j.celrep.2018.08.015","article-title":"Triglycerides promote lipid homeostasis during Hypoxic stress by balancing fatty acid Saturation","volume":"24","author":"Ackerman","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.jbc.2024.107168_bib38","doi-asserted-by":"crossref","first-page":"214","DOI":"10.3390\/v12020214","article-title":"Porcine epidemic diarrhea virus (PEDV) ORF3 enhances viral proliferation by inhibiting apoptosis of infected cells","volume":"12","author":"Si","year":"2020","journal-title":"Viruses"},{"key":"10.1016\/j.jbc.2024.107168_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetmic.2021.109326","article-title":"G\u00a0protein-coupled receptor 17 restricts rabies virus replication via BAK-mediated apoptosis","volume":"265","author":"Liu","year":"2022","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.jbc.2024.107168_bib40","doi-asserted-by":"crossref","first-page":"10741","DOI":"10.1128\/JVI.00394-11","article-title":"Encephalomyocarditis virus 2A protein is required for viral pathogenesis and inhibition of apoptosis","volume":"85","author":"Carocci","year":"2011","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jbc.2024.107168_bib41","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.1038\/s41418-021-00859-z","article-title":"Organelle-specific regulation of ferroptosis","volume":"28","author":"Chen","year":"2021","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.jbc.2024.107168_bib42","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1016\/j.cmet.2021.05.016","article-title":"Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects","volume":"33","author":"Dierge","year":"2021","journal-title":"Cell Metab."},{"key":"10.1016\/j.jbc.2024.107168_bib43","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.bbrc.2018.12.039","article-title":"Lipid storage and lipophagy regulates ferroptosis","volume":"508","author":"Bai","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jbc.2024.107168_bib44","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1007\/s11684-020-0804-7","article-title":"Orlistat induces ferroptosis-like cell death of lung cancer cells","volume":"15","author":"Zhou","year":"2021","journal-title":"Front. Med."},{"key":"10.1016\/j.jbc.2024.107168_bib45","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/s41392-020-00216-5","article-title":"The interaction between ferroptosis and lipid metabolism in cancer","volume":"5","author":"Li","year":"2020","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.jbc.2024.107168_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2019.101107","article-title":"NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis","volume":"23","author":"Dodson","year":"2019","journal-title":"Redox Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib47","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/s41568-022-00459-0","article-title":"Targeting ferroptosis as a vulnerability in cancer","volume":"22","author":"Lei","year":"2022","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.jbc.2024.107168_bib48","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.bbalip.2013.10.018","article-title":"Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol","volume":"1841","author":"Kuch","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.jbc.2024.107168_bib49","doi-asserted-by":"crossref","first-page":"7038","DOI":"10.1111\/febs.16059","article-title":"Signaling pathways and defense mechanisms of ferroptosis","volume":"289","author":"Liu","year":"2022","journal-title":"FEBS J."},{"key":"10.1016\/j.jbc.2024.107168_bib50","first-page":"184","article-title":"Lipid metabolism and ferroptosis","volume":"10","author":"Lee","year":"2021","journal-title":"Biology (Basel)"},{"key":"10.1016\/j.jbc.2024.107168_bib51","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1186\/s13059-020-02150-9","article-title":"A\u00a0novel antiviral lncRNA, EDAL, shields a T309 O-GlcNAcylation site to promote EZH2 lysosomal degradation","volume":"21","author":"Sui","year":"2020","journal-title":"Genome Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib52","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1016\/j.cell.2022.06.003","article-title":"Ferroptosis turns 10: emerging mechanisms, physiological functions, and therapeutic applications","volume":"185","author":"Stockwell","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.jbc.2024.107168_bib53","doi-asserted-by":"crossref","first-page":"4968","DOI":"10.3390\/ijms20194968","article-title":"Programmed cell-death by ferroptosis: antioxidants as Mitigators","volume":"20","author":"Kajarabille","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jbc.2024.107168_bib54","doi-asserted-by":"crossref","DOI":"10.1002\/pmic.201800311","article-title":"GPX4 at the Crossroads of lipid homeostasis and ferroptosis","volume":"19","author":"Forcina","year":"2019","journal-title":"Proteomics"},{"key":"10.1016\/j.jbc.2024.107168_bib55","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.freeradbiomed.2020.02.027","article-title":"Lipid peroxidation and ferroptosis: the role of GSH and GPx4","volume":"152","author":"Ursini","year":"2020","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jbc.2024.107168_bib56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mam.2008.08.006","article-title":"Glutathione: overview of its protective roles, measurement, and biosynthesis","volume":"30","author":"Forman","year":"2009","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.jbc.2024.107168_bib57","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3389\/fphar.2014.00196","article-title":"Glutathione: new roles in redox signaling for an old antioxidant","volume":"5","author":"Aquilano","year":"2014","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jbc.2024.107168_bib58","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s13238-020-00789-5","article-title":"Cystine transporter SLC7A11\/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy","volume":"12","author":"Koppula","year":"2021","journal-title":"Protein Cell"},{"key":"10.1016\/j.jbc.2024.107168_bib59","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/nature23007","article-title":"Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway","volume":"547","author":"Viswanathan","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2024.107168_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102408","article-title":"Acute lymphoblastic leukemia necessitates GSH-dependent ferroptosis defenses to overcome FSP1-epigenetic silencing","volume":"55","author":"Pontel","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib61","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/s41586-019-1707-0","article-title":"FSP1 is a glutathione-independent ferroptosis suppressor","volume":"575","author":"Doll","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2024.107168_bib62","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1038\/s41586-021-03539-7","article-title":"DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer","volume":"593","author":"Mao","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2024.107168_bib63","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1038\/s41589-020-0613-y","article-title":"Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers","volume":"16","author":"Soula","year":"2020","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.jbc.2024.107168_bib64","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.cmet.2008.07.005","article-title":"Glutathione peroxidase 4 senses and translates oxidative stress into 12\/15-lipoxygenase dependent- and AIF-mediated cell death","volume":"8","author":"Seiler","year":"2008","journal-title":"Cell Metab."},{"key":"10.1016\/j.jbc.2024.107168_bib65","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0022-1759(97)00212-3","article-title":"Development of a fluorescent antibody virus neutralisation test (FAVN test) for the quantitation of rabies-neutralising antibody","volume":"212","author":"Cliquet","year":"1998","journal-title":"J.\u00a0Immunol. Methods"},{"key":"10.1016\/j.jbc.2024.107168_bib66","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/s42255-022-00567-z","article-title":"A\u00a0glucose-like metabolite deficient in diabetes inhibits cellular entry of SARS-CoV-2","volume":"4","author":"Tong","year":"2022","journal-title":"Nat. Metab."},{"key":"10.1016\/j.jbc.2024.107168_bib67","doi-asserted-by":"crossref","first-page":"3644","DOI":"10.1038\/s41467-021-23902-6","article-title":"iPLA2beta-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4","volume":"12","author":"Chen","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jbc.2024.107168_bib68","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1038\/s41419-019-2064-5","article-title":"ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation","volume":"10","author":"Park","year":"2019","journal-title":"Cell Death Dis."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925824016636?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925824016636?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T16:46:30Z","timestamp":1762188390000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925824016636"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":68,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S0021925824016636"],"URL":"https:\/\/doi.org\/10.1016\/j.jbc.2024.107168","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuroinvasive virus facilitates viral replication by employing lipid droplets to reduce arachidonic acid-induced ferroptosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jbc.2024.107168","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}],"article-number":"107168"}}