{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T14:27:50Z","timestamp":1791556070314,"version":"4.3.4"},"reference-count":86,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,28]],"date-time":"2024-07-28T00:00:00Z","timestamp":1722124800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["2R01AI112956-06"],"award-info":[{"award-number":["2R01AI112956-06"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006631","name":"Animal and Plant Health Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006631","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"BBSRC","doi-asserted-by":"publisher","award":["BB\/T00343X\/1"],"award-info":[{"award-number":["BB\/T00343X\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.jbc.2024.107617","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T06:57:41Z","timestamp":1722322661000},"page":"107617","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lack of prion transmission barrier in human PrP transgenic Drosophila"],"prefix":"10.1016","volume":"300","author":[{"given":"Alana M.","family":"Thackray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1918-6207","authenticated-orcid":false,"given":"Erin E.","family":"McNulty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy V.","family":"Nalls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Comoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn","family":"Telling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie L.","family":"Benestad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Andr\u00e9oletti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candace K.","family":"Mathiason","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"Bujdoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbc.2024.107617_bib1","series-title":"Prion Biology and Diseases","author":"Prusiner","year":"2004"},{"key":"10.1016\/j.jbc.2024.107617_bib2","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1126\/science.6801762","article-title":"Novel proteinaceous infectious particles cause scrapie","volume":"216","author":"Prusiner","year":"1982","journal-title":"Science"},{"key":"10.1016\/j.jbc.2024.107617_bib3","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.cell.2005.02.011","article-title":"In\u00a0vitro generation of infectious scrapie prions","volume":"121","author":"Castilla","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.jbc.2024.107617_bib4","doi-asserted-by":"crossref","first-page":"9741","DOI":"10.1073\/pnas.0702662104","article-title":"Formation of native prions from minimal components in\u00a0vitro","volume":"104","author":"Deleault","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2024.107617_bib5","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1126\/science.1100195","article-title":"Synthetic mammalian prions","volume":"305","author":"Legname","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.jbc.2024.107617_bib6","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1073\/pnas.0409079102","article-title":"Strain-specified characteristics of mouse synthetic prions","volume":"102","author":"Legname","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2024.107617_bib7","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1126\/science.1183748","article-title":"Generating a prion with bacterially expressed recombinant prion protein","volume":"327","author":"Wang","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.jbc.2024.107617_bib8","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/s40478-023-01640-8","article-title":"Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation","volume":"11","author":"Erana","year":"2023","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.jbc.2024.107617_bib9","first-page":"1552","article-title":"Pathologie animale : la maladie dite de la tremblante du mouton est-elle inoculable?","volume":"203","author":"Culli\u00e9","year":"1936","journal-title":"Comptes rendus de l'Acad\u00e9mie des Sci. D"},{"key":"10.1016\/j.jbc.2024.107617_bib10","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/S0368-1742(59)80029-1","article-title":"Experimental production of scrapie in goats","volume":"69","author":"Pattison","year":"1959","journal-title":"J.\u00a0Comp. Pathol."},{"key":"10.1016\/j.jbc.2024.107617_bib11","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/209794a0","article-title":"Experimental transmission of a Kuru-like syndrome to chimpanzees","volume":"209","author":"Gajdusek","year":"1966","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2024.107617_bib12","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1126\/science.161.3839.388","article-title":"Creutzfeldt-Jakob disease (spongiform encephalopathy): transmission to the chimpanzee","volume":"161","author":"Gibbs","year":"1968","journal-title":"Science"},{"key":"10.1016\/j.jbc.2024.107617_bib13","doi-asserted-by":"crossref","first-page":"10248","DOI":"10.1073\/pnas.97.18.10248","article-title":"Species-barrier-independent prion replication in apparently resistant species","volume":"97","author":"Hill","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2024.107617_bib14","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1038\/33834","article-title":"Scrapie infectivity found in resistant species","volume":"392","author":"Race","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2024.107617_bib15","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1099\/0022-1317-39-3-487","article-title":"Evidence that the transmission of one source of scrapie agent to hamsters involves separation of agent strains from a mixture","volume":"39","author":"Kimberlin","year":"1978","journal-title":"J.\u00a0Gen. Virol."},{"key":"10.1016\/j.jbc.2024.107617_bib16","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/978-1-4939-7244-9_16","article-title":"Insights into mechanisms of transmission and pathogenesis from transgenic mouse models of prion diseases","volume":"1658","author":"Moreno","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.jbc.2024.107617_bib17","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/0092-8674(89)90608-9","article-title":"Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques","volume":"59","author":"Scott","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.jbc.2024.107617_bib18","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/0092-8674(90)90134-Z","article-title":"Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication","volume":"63","author":"Prusiner","year":"1990","journal-title":"Cell"},{"key":"10.1016\/j.jbc.2024.107617_bib19","doi-asserted-by":"crossref","first-page":"6358","DOI":"10.1093\/emboj\/cdf653","article-title":"BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein","volume":"21","author":"Asante","year":"2002","journal-title":"EMBO J."},{"key":"10.1016\/j.jbc.2024.107617_bib20","doi-asserted-by":"crossref","first-page":"15137","DOI":"10.1073\/pnas.96.26.15137","article-title":"Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans","volume":"96","author":"Scott","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2024.107617_bib21","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1126\/science.1138718","article-title":"A\u00a0general model of prion strains and their pathogenicity","volume":"318","author":"Collinge","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.jbc.2024.107617_bib22","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1126\/science.182.4107.67","article-title":"Experimental subacute spongiform virus encephalopathies in primates and other laboratory animals","volume":"182","author":"Gibbs","year":"1973","journal-title":"Science"},{"key":"10.1016\/j.jbc.2024.107617_bib23","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/236073a0","article-title":"Transmission of scrapie to the cynomolgus monkey (Macaca fascicularis)","volume":"236","author":"Gibbs","year":"1972","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2024.107617_bib24","doi-asserted-by":"crossref","DOI":"10.1038\/srep11573","article-title":"Transmission of scrapie prions to primate after an extended silent incubation period","volume":"5","author":"Comoy","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jbc.2024.107617_bib25","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/S0140-6736(97)09468-3","article-title":"Case-control study of risk factors of creutzfeldt-jakob disease in Europe during 1993-95. European union (EU) collaborative study group of creutzfeldt-jakob disease (CJD)","volume":"351","author":"van Duijn","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.jbc.2024.107617_bib26","first-page":"353","article-title":"Occupational risk factors for the sporadic form of Creutzfeldt-Jakob disease","volume":"94","author":"Cocco","year":"2003","journal-title":"Med. Lav."},{"key":"10.1016\/j.jbc.2024.107617_bib27","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0140-6736(96)91412-9","article-title":"A\u00a0new variant of Creutzfeldt-Jakob disease in the UK","volume":"347","author":"Will","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.jbc.2024.107617_bib28","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1136\/vr.121.18.419","article-title":"A\u00a0novel progressive spongiform encephalopathy in cattle","volume":"121","author":"Wells","year":"1987","journal-title":"Vet. Rec."},{"key":"10.1016\/j.jbc.2024.107617_bib29","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/39057","article-title":"Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent","volume":"389","author":"Bruce","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2024.107617_bib30","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/38925","article-title":"The same prion strain causes vCJD and BSE","volume":"389","author":"Hill","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2024.107617_bib31","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.3201\/eid2406.172007","article-title":"Prion disease in dromedary camels, Algeria","volume":"24","author":"Babelhadj","year":"2018","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.jbc.2024.107617_bib32","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/s13567-016-0375-4","article-title":"First case of chronic wasting disease in Europe in a Norwegian free-ranging reindeer","volume":"47","author":"Benestad","year":"2016","journal-title":"Vet. Res."},{"key":"10.1016\/j.jbc.2024.107617_bib33","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/s13028-021-00606-x","article-title":"Chronic wasting disease in Europe: new strains on the horizon","volume":"63","author":"Tranulis","year":"2021","journal-title":"Acta Vet. Scand."},{"key":"10.1016\/j.jbc.2024.107617_bib34","doi-asserted-by":"crossref","first-page":"824","DOI":"10.3390\/foods12040824","article-title":"The zoonotic potential of chronic wasting disease-A review","volume":"12","author":"Tranulis","year":"2023","journal-title":"Foods"},{"key":"10.1016\/j.jbc.2024.107617_bib35","doi-asserted-by":"crossref","first-page":"89","DOI":"10.7589\/0090-3558-16.1.89","article-title":"Chronic wasting disease of captive mule deer: a spongiform encephalopathy","volume":"16","author":"Williams","year":"1980","journal-title":"J.\u00a0Wildl. Dis."},{"key":"10.1016\/j.jbc.2024.107617_bib36","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00441-022-03590-4","article-title":"Large animal models for chronic wasting disease","volume":"392","author":"Mathiason","year":"2023","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.jbc.2024.107617_bib37","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1292\/jvms.67.753","article-title":"Additional cases of chronic wasting disease in imported deer in Korea","volume":"67","author":"Kim","year":"2005","journal-title":"J.\u00a0Vet. Med. Sci."},{"key":"10.1016\/j.jbc.2024.107617_bib38","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1177\/104063870501700313","article-title":"Experimental transmission of chronic wasting disease agent from mule deer to cattle by the intracerebral route","volume":"17","author":"Hamir","year":"2005","journal-title":"J.\u00a0Vet. Diagn. Invest."},{"key":"10.1016\/j.jbc.2024.107617_bib39","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1177\/104063870601800606","article-title":"Transmission of chronic wasting disease of mule deer to Suffolk sheep following intracerebral inoculation","volume":"18","author":"Hamir","year":"2006","journal-title":"J.\u00a0Vet. Diagn. Invest."},{"key":"10.1016\/j.jbc.2024.107617_bib40","doi-asserted-by":"crossref","first-page":"e00926-17","DOI":"10.1128\/JVI.00926-17","article-title":"Experimental transmission of the chronic wasting disease agent to swine after oral or intracranial inoculation","volume":"91","author":"Moore","year":"2017","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jbc.2024.107617_bib41","doi-asserted-by":"crossref","DOI":"10.1002\/pro.4477","article-title":"Probing the origin of prion protein misfolding via reconstruction of ancestral proteins","volume":"31","author":"Cortez","year":"2022","journal-title":"Protein Sci."},{"key":"10.1016\/j.jbc.2024.107617_bib42","first-page":"2700","article-title":"Mammalian prion propagation in PrP transgenic Drosophila","volume":"141","author":"Thackray","year":"2018","journal-title":"Brain"},{"key":"10.1016\/j.jbc.2024.107617_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.100878","article-title":"A\u00a0new model for sensitive detection of zoonotic prions by PrP transgenic Drosophila","volume":"297","author":"Thackray","year":"2021","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2024.107617_bib44","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1042\/BCJ20230247","article-title":"Genetic modulation of CWD prion propagation in cervid PrP Drosophila","volume":"480","author":"Thackray","year":"2023","journal-title":"Biochem. J."},{"key":"10.1016\/j.jbc.2024.107617_bib45","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1006\/jmbi.1994.0030","article-title":"Prion protein gene variation among primates","volume":"245","author":"Schatzl","year":"1995","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.jbc.2024.107617_bib46","doi-asserted-by":"crossref","first-page":"3312","DOI":"10.1073\/pnas.0611511104","article-title":"An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases","volume":"104","author":"Bischof","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jbc.2024.107617_bib47","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1042\/BJ20140129","article-title":"Prion-induced and spontaneous formation of transmissible toxicity in PrP transgenic Drosophila","volume":"463","author":"Thackray","year":"2014","journal-title":"Biochem. J."},{"key":"10.1016\/j.jbc.2024.107617_bib48","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0925-4773(95)00379-7","article-title":"Expression and targeting of Syrian hamster prion protein induced by heat shock in transgenic Drosophila melanogaster","volume":"51","author":"Raeber","year":"1995","journal-title":"Mech. Dev."},{"key":"10.1016\/j.jbc.2024.107617_bib49","doi-asserted-by":"crossref","first-page":"12408","DOI":"10.1523\/JNEUROSCI.3372-06.2006","article-title":"Accelerated accumulation of misfolded prion protein and spongiform degeneration in a Drosophila model of Gerstmann-Straussler-Scheinker syndrome","volume":"26","author":"Gavin","year":"2006","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.jbc.2024.107617_bib50","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1016\/0092-8674(93)90360-3","article-title":"Mice devoid of PrP are resistant to scrapie","volume":"73","author":"Bueler","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.jbc.2024.107617_bib51","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1126\/science.1090187","article-title":"Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis","volume":"302","author":"Mallucci","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.jbc.2024.107617_bib52","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.3201\/eid2309.161948","article-title":"Protective effect of Val(129)-PrP against bovine spongiform encephalopathy but not variant Creutzfeldt-Jakob disease","volume":"23","author":"Fernandez-Borges","year":"2017","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.jbc.2024.107617_bib53","doi-asserted-by":"crossref","first-page":"21659","DOI":"10.1074\/jbc.M113.470328","article-title":"Characterization of variant Creutzfeldt-Jakob disease prions in prion protein-humanized mice carrying distinct codon 129 genotypes","volume":"288","author":"Takeuchi","year":"2013","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2024.107617_bib54","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1474-4422(08)70265-5","article-title":"Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study","volume":"8","author":"Mead","year":"2009","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jbc.2024.107617_bib55","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1038\/381743a0","article-title":"BSE transmission to macaques","volume":"381","author":"Lasmezas","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.jbc.2024.107617_bib56","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0140-6736(04)15487-1","article-title":"Tissue distribution of bovine spongiform encephalopathy agent in primates after intravenous or oral infection","volume":"363","author":"Herzog","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.jbc.2024.107617_bib57","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1126\/science.1103932","article-title":"Human prion protein with valine 129 prevents expression of variant CJD phenotype","volume":"306","author":"Wadsworth","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.jbc.2024.107617_bib58","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.3201\/eid1210.060019","article-title":"Human prion disease and relative risk associated with chronic wasting disease","volume":"12","author":"Mawhinney","year":"2006","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.jbc.2024.107617_bib59","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1001\/archneur.64.3.439","article-title":"Colorado surveillance program for chronic wasting disease transmission to humans: lessons from 2 highly suspicious but negative cases","volume":"64","author":"Anderson","year":"2007","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.jbc.2024.107617_bib60","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1001\/archneur.58.10.1673","article-title":"Creutzfeldt-Jakob disease in unusually young patients who consumed venison","volume":"58","author":"Belay","year":"2001","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.jbc.2024.107617_bib61","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.puhe.2014.06.012","article-title":"Six-year follow-up of a point-source exposure to CWD contaminated venison in an Upstate New York community: risk behaviours and health outcomes 2005-2011","volume":"128","author":"Olszowy","year":"2014","journal-title":"Public Health"},{"key":"10.1016\/j.jbc.2024.107617_bib62","first-page":"626","article-title":"Molecular phylogeny and evolution of primate mitochondrial DNA","volume":"5","author":"Hayasaka","year":"1988","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.jbc.2024.107617_bib63","first-page":"95","article-title":"Prion 2022 Conference abstract (pp153): transmission of prion infectivity from CWD-infected macaque tissues to rodent models demonstrates the zoonotic potential of chronic wasting disease","volume":"16","author":"Hannaoui","year":"2022","journal-title":"Prion"},{"key":"10.1016\/j.jbc.2024.107617_bib64","doi-asserted-by":"crossref","first-page":"e00550-18","DOI":"10.1128\/JVI.00550-18","article-title":"Lack of transmission of chronic wasting disease to cynomolgus macaques","volume":"92","author":"Race","year":"2018","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jbc.2024.107617_bib65","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1007\/s00401-022-02482-9","article-title":"Transmission of cervid prions to humanized mice demonstrates the zoonotic potential of CWD","volume":"144","author":"Hannaoui","year":"2022","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.jbc.2024.107617_bib66","doi-asserted-by":"crossref","first-page":"207","DOI":"10.3390\/biom11020207","article-title":"Prion diseases: a unique transmissible agent or a model for neurodegenerative diseases?","volume":"11","author":"Ritchie","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.jbc.2024.107617_bib67","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003990","article-title":"Evidence that bank vole PrP is a universal acceptor for prions","volume":"10","author":"Watts","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jbc.2024.107617_bib68","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jcpa.2004.08.002","article-title":"Primary isolation of the bovine spongiform encephalopathy agent in mice: agent definition based on a review of 150 transmissions","volume":"132","author":"Green","year":"2005","journal-title":"J.\u00a0Comp. Pathol."},{"key":"10.1016\/j.jbc.2024.107617_bib69","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1098\/rstb.1994.0036","article-title":"Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier","volume":"343","author":"Bruce","year":"1994","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.jbc.2024.107617_bib70","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s10719-018-9835-6","article-title":"Sialylation and sialyltransferase in insects","volume":"35","author":"Ghosh","year":"2018","journal-title":"Glycoconj J."},{"key":"10.1016\/j.jbc.2024.107617_bib71","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1021\/cb700178s","article-title":"Exploring the structural diversity of mammalian carbohydrates (\"glycospace\") by statistical databank analysis","volume":"2","author":"Werz","year":"2007","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.jbc.2024.107617_bib72","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004366","article-title":"Sialylation of prion protein controls the rate of prion amplification, the cross-species barrier, the ratio of PrPSc glycoform and prion infectivity","volume":"10","author":"Katorcha","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jbc.2024.107617_bib73","doi-asserted-by":"crossref","first-page":"3236","DOI":"10.1093\/brain\/awac144","article-title":"Clearance of variant Creutzfeldt-Jakob disease prions in\u00a0vivo by the Hsp70 disaggregase system","volume":"145","author":"Thackray","year":"2022","journal-title":"Brain"},{"key":"10.1016\/j.jbc.2024.107617_bib74","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/bs.pmbts.2020.07.009","article-title":"Cofactor molecules: essential partners for infectious prions","volume":"175","author":"Supattapone","year":"2020","journal-title":"Prog. Mol. Biol. Transl Sci."},{"key":"10.1016\/j.jbc.2024.107617_bib75","doi-asserted-by":"crossref","first-page":"254","DOI":"10.3389\/fncel.2020.00254","article-title":"Insight from animals resistant to prion diseases: deciphering the genotype - morphotype - phenotype code for the prion protein","volume":"14","author":"Myers","year":"2020","journal-title":"Front Cell Neurosci."},{"key":"10.1016\/j.jbc.2024.107617_bib76","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1093\/genetics\/156.3.1117","article-title":"The necrotic gene in Drosophila corresponds to one of a cluster of three serpin transcripts mapping at 43A1.2","volume":"156","author":"Green","year":"2000","journal-title":"Genetics"},{"key":"10.1016\/j.jbc.2024.107617_bib77","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1001319","article-title":"Sheep and goat BSE propagate more efficiently than cattle BSE in human PrP transgenic mice","volume":"7","author":"Padilla","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.jbc.2024.107617_bib78","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.3201\/eid2012.140548","article-title":"Transmission characteristics of variably protease-sensitive prionopathy","volume":"20","author":"Notari","year":"2014","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.jbc.2024.107617_bib79","doi-asserted-by":"crossref","first-page":"11197","DOI":"10.1128\/JVI.01454-08","article-title":"Molecular and transmission characteristics of primary-passaged ovine scrapie isolates in conventional and ovine PrP transgenic mice","volume":"82","author":"Thackray","year":"2008","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jbc.2024.107617_bib80","doi-asserted-by":"crossref","first-page":"11247","DOI":"10.1074\/jbc.M407006200","article-title":"Screening of 145 anti-PrP monoclonal antibodies for their capacity to inhibit PrPSc replication in infected cells","volume":"280","author":"Feraudet","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.jbc.2024.107617_bib81","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0216621","article-title":"Comparison of conventional, amplification and bio-assay detection methods for a chronic wasting disease inoculum pool","volume":"14","author":"McNulty","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.jbc.2024.107617_bib82","doi-asserted-by":"crossref","first-page":"e00501","DOI":"10.1128\/JVI.00501-17","article-title":"Infectious prions in the pregnancy microenvironment of Chronic Wasting Disease-infected Reeves' muntjac deer","volume":"91","author":"Nalls","year":"2017","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.jbc.2024.107617_bib83","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0074377","article-title":"Rapid antemortem detection of CWD prions in deer saliva","volume":"8","author":"Henderson","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jbc.2024.107617_bib84","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1002\/path.4954","article-title":"Infectivity in bone marrow from sporadic CJD patients","volume":"243","author":"Huor","year":"2017","journal-title":"J.\u00a0Pathol."},{"key":"10.1016\/j.jbc.2024.107617_bib85","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/s00705-002-0958-4","article-title":"Early detection of PrPres in BSE-infected bovine PrP transgenic mice","volume":"148","author":"Castilla","year":"2003","journal-title":"Arch. Virol."},{"key":"10.1016\/j.jbc.2024.107617_bib86","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0021-9975(68)90006-6","article-title":"The sequential development of the brain lesion of scrapie in three strains of mice","volume":"78","author":"Fraser","year":"1968","journal-title":"J.\u00a0Comp. Pathol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925824021185?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925824021185?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T00:37:12Z","timestamp":1734395832000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925824021185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":86,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S0021925824021185"],"URL":"https:\/\/doi.org\/10.1016\/j.jbc.2024.107617","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lack of prion transmission barrier in human PrP transgenic Drosophila","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jbc.2024.107617","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}],"article-number":"107617"}}