{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T15:16:51Z","timestamp":1793459811017,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AR063905"],"award-info":[{"award-number":["AR063905"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AR033236"],"award-info":[{"award-number":["AR033236"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbiomech.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biomechanics"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1016\/j.jbiomech.2015.02.064","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T17:09:34Z","timestamp":1426093774000},"page":"1364-1370","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"title":["Biomechanical properties of murine meniscus surface via AFM-based nanoindentation"],"prefix":"10.1016","volume":"48","author":[{"given":"Qing","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basak","family":"Doyran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura W.","family":"Gamer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X. Lucas","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Ortiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan J.","family":"Grodzinsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicki","family":"Rosen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4180-1288","authenticated-orcid":false,"given":"Lin","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbiomech.2015.02.064_bib1","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1097\/01.bor.0000240369.39713.af","article-title":"Animal models of osteoarthritis: lessons learned while seeking the \u2018Holy Grail\u2019","volume":"18","author":"Ameye","year":"2006","journal-title":"Curr. Opin. Rheumatol."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib2","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1023\/B:ABME.0000017541.82498.37","article-title":"A framework for the in vivo pathomechanics of osteoarthritis at the knee","volume":"32","author":"Andriacchi","year":"2004","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib3","first-page":"371","article-title":"Collagen orientations in the meniscus of the knee joint","volume":"140","author":"Aspden","year":"1985","journal-title":"J. Anat."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib4","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.bone.2012.03.009","article-title":"Functional characterization of normal and degraded bovine meniscus: rate-dependent indentation and friction studies","volume":"51","author":"Baro","year":"2012","journal-title":"Bone"},{"key":"10.1016\/j.jbiomech.2015.02.064_bib5","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.matbio.2014.05.008","article-title":"Nanomechanical phenotype of chondroadherin-null murine articular cartilage","volume":"38","author":"Batista","year":"2014","journal-title":"Matrix Biol."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib6","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/jemt.1070260603","article-title":"Comparison of hexamethyldisilazane (HMDS), peldri II, and critical-point drying methods for scanning electron-microscopy of biological specimens","volume":"26","author":"Bray","year":"1993","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib7","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.rdc.2008.05.009","article-title":"The role of the meniscus in osteoarthritis genesis","volume":"34","author":"Englund","year":"2008","journal-title":"Rheum. Dis. Clin. North Am."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib8","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/nrrheum.2014.46","article-title":"Mouse models of osteoarthritis: modelling risk factors and assessing outcomes","volume":"10","author":"Fang","year":"2014","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib9","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/00003086-199003000-00004","article-title":"Material properties and structure-function-relationships in the menisci","volume":"252","author":"Fithian","year":"1990","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib10","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.joca.2007.03.006","article-title":"The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129\/SvEv mouse","volume":"15","author":"Glasson","year":"2007","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib11","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1016\/j.bpj.2011.02.031","article-title":"Time-dependent nanomechanics of cartilage","volume":"100","author":"Han","year":"2011","journal-title":"Biophys. J."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib12","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1136\/ard.43.4.635","article-title":"Chemical changes of human knee joint menisci in various stages of degeneration","volume":"43","author":"Herwig","year":"1984","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib13","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1002\/art.21724","article-title":"The association of meniscal pathologic changes with cartilage loss in symptomatic knee ostoearthritis","volume":"54","author":"Hunter","year":"2006","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib14","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1002\/jbm.820290706","article-title":"Interspecies variation of compressive biomechanical properties of the meniscus","volume":"29","author":"Joshi","year":"1995","journal-title":"J. Biomed. Mater. Res."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib15","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.joca.2010.05.017","article-title":"Changes of human menisci in osteoarthritic knee joints","volume":"18","author":"Katsuragawa","year":"2010","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib16","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1002\/jor.1100100308","article-title":"Meniscal repair by fibrocartilage? An experimental study in the dog","volume":"10","author":"Klompmaker","year":"1992","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib17","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/j.joca.2010.05.020","article-title":"Meniscus and cartilage exhibit distinct intra-tissue strain distributions under unconfined compression","volume":"18","author":"Lai","year":"2010","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib18","doi-asserted-by":"crossref","first-page":"7411","DOI":"10.1016\/j.biomaterials.2011.06.037","article-title":"The knee meniscus: structure-function, pathophysiology, current repair techniques, and prospects for regeneration","volume":"32","author":"Makris","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.jbiomech.2015.02.064_bib19","doi-asserted-by":"crossref","first-page":"e57683","DOI":"10.1371\/journal.pone.0057683","article-title":"Of mice, men and elephants: the relation between articular cartilage thickness and body mass","volume":"8","author":"Malda","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jbiomech.2015.02.064_bib20","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1006\/abbi.1997.0492","article-title":"Aggrecan turnover in human articular cartilage: use of aspartic acid racemization as a marker of molecular age","volume":"350","author":"Maroudas","year":"1998","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib21","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.jbiomech.2012.09.003","article-title":"Depth-dependent anisotropy of the micromechanical properties of the extracellular and pericellular matrices of articular cartilage evaluated via atomic force microscopy","volume":"46","author":"McLeod","year":"2013","journal-title":"J. Biomech."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib22","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1016\/j.jbiomech.2012.06.017","article-title":"Nanoindentation of human meniscal surfaces","volume":"45","author":"Moyer","year":"2012","journal-title":"J. Biomech."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib23","doi-asserted-by":"crossref","first-page":"6624","DOI":"10.1016\/j.actbio.2012.12.033","article-title":"Indentation properties and glycosaminoglycan content of human menisci in the deep zone","volume":"9","author":"Moyer","year":"2013","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib24","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jbiomech.2014.11.012","article-title":"High-bandwidth AFM-based rheology is a sensitive indicator of early cartilage aggrecan degradation relevant to mouse models of osteoarthritis","volume":"48","author":"Nia","year":"2015","journal-title":"J. Biomech."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib25","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1016\/j.bpj.2011.09.011","article-title":"Poroelasticity of cartilage at the nanoscale","volume":"101","author":"Nia","year":"2011","journal-title":"Biophys. J."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib26","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.joca.2011.05.008","article-title":"Macroscopic and histopathologic analysis of human knee menisci in aging and osteoarthritis","volume":"19","author":"Pauli","year":"2011","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ar.1091050102","article-title":"The ossicles of the semilunar cartilages of rodents","volume":"105","author":"Pedersen","year":"1949","journal-title":"Anat. Rec."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib28","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s004290050141","article-title":"Collagenous fibril texture of the human knee joint menisci","volume":"197","author":"Petersen","year":"1998","journal-title":"Anat. Embryol."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib29","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s11420-011-9248-6","article-title":"Osteoarthritis as a whole joint disease","volume":"8","author":"Poole","year":"2012","journal-title":"HSSJ"},{"key":"10.1016\/j.jbiomech.2015.02.064_bib30","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1002\/jor.1100070602","article-title":"Material properties of the normal medial bovine meniscus","volume":"7","author":"Proctor","year":"1989","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib31","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1021\/bm401611b","article-title":"Molecular adhesion between cartilage extracellular matrix macromolecules","volume":"15","author":"Rojas","year":"2014","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.jbiomech.2015.02.064_bib32","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.joca.2009.08.003","article-title":"Depth-wise progression of osteoarthritis in human articular cartilage: investigation of composition, structure and biomechanics","volume":"18","author":"Saarakkala","year":"2010","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib33","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1080\/01418610208235695","article-title":"Time-dependent viscoelastic relation between load and penetration for an axisymmetric indenter","volume":"82","author":"Sakai","year":"2002","journal-title":"Philos. Mag. A"},{"key":"10.1016\/j.jbiomech.2015.02.064_bib34","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1002\/jor.22362","article-title":"Atomic force microscopy reveals regional variations in the micromechanical properties of the pericellular and extracellular matrices of the meniscus","volume":"31","author":"Sanchez-Adams","year":"2013","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib35","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/jor.1100120205","article-title":"Radial tie fibers influence the tensile properties of the bovine medial meniscus","volume":"12","author":"Skaggs","year":"1994","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib36","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s00223-003-0101-x","article-title":"Growth of C57BL\/6 mice and the material and mechanical properties of cortical bone from the tibia","volume":"74","author":"Somerville","year":"2004","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib37","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1115\/1.2798330","article-title":"A fibril-network-reinforced biphasic model of cartilage in unconfined compression","volume":"121","author":"Soulhat","year":"1999","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib38","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/0021-9290(92)90038-3","article-title":"A transversely isotropic biphasic finite element model of the meniscus","volume":"25","author":"Spilker","year":"1992","journal-title":"J. Biomech."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib39","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/nnano.2008.410","article-title":"Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy","volume":"4","author":"Stolz","year":"2009","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib40","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1243\/095441105X34329","article-title":"Tensile and compressive properties of the medial rabbit meniscus","volume":"219","author":"Sweigart","year":"2005","journal-title":"Proc. Inst. Mech. Eng. H"},{"key":"10.1016\/j.jbiomech.2015.02.064_bib41","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1114\/B:ABME.0000049040.70767.5c","article-title":"Intraspecies and interspecies comparison of the compressive properties of the medial meniscus","volume":"32","author":"Sweigart","year":"2004","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib42","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/j.1365-2818.2012.03606.x","article-title":"Helium ion microscopy for high-resolution visualization of the articular cartilage collagen network","volume":"246","author":"Vanden Berg-Foels","year":"2012","journal-title":"J. Microsc."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib43","doi-asserted-by":"crossref","first-page":"39027","DOI":"10.1074\/jbc.M006700200","article-title":"Effect of collagen turnover on the accumulation of advanced glycation end products","volume":"275","author":"Verzijl","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib44","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0141-5425(83)90036-5","article-title":"Shock absorption of meniscectomized and painful knees: a comparative in vivo study","volume":"5","author":"Voloshin","year":"1983","journal-title":"J. Biomed. Eng."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib45","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1097\/00003086-197506000-00027","article-title":"The role of the menisci in force transmission across the knee","author":"Walker","year":"1975","journal-title":"Clin. Orthop. Relat. Res."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib46","doi-asserted-by":"crossref","first-page":"2592","DOI":"10.1016\/j.bpj.2014.09.044","article-title":"Long range force transmission in fibrous matrices enabled by tension-driven alignment of fibers","volume":"107","author":"Wang","year":"2014","journal-title":"Biophys. J."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib47","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1002\/art.37947","article-title":"Meniscus body position, size, and shape in persons with and persons without radiographic knee osteoarthritis: quantitative analyses of knee magnetic resonance images from the osteoarthritis initiative","volume":"65","author":"Wenger","year":"2013","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib48","doi-asserted-by":"crossref","first-page":"3062","DOI":"10.1002\/art.38780","article-title":"Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening","volume":"66","author":"Willard","year":"2014","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.jbiomech.2015.02.064_bib49","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/jmri.21392","article-title":"Depth-dependent profiles of glycosaminoglycans in articular cartilage by \u00b5MRI and histochemistry","volume":"28","author":"Xia","year":"2008","journal-title":"J. Magn. Reson. Imaging"}],"container-title":["Journal of Biomechanics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021929015001578?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021929015001578?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T00:19:18Z","timestamp":1651450758000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021929015001578"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":49,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S0021929015001578"],"URL":"https:\/\/doi.org\/10.1016\/j.jbiomech.2015.02.064","relation":{},"ISSN":["0021-9290"],"issn-type":[{"value":"0021-9290","type":"print"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biomechanical properties of murine meniscus surface via AFM-based nanoindentation","name":"articletitle","label":"Article Title"},{"value":"Journal of Biomechanics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jbiomech.2015.02.064","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}