{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T15:16:25Z","timestamp":1785856585545,"version":"3.56.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,11,4]],"date-time":"2019-11-04T00:00:00Z","timestamp":1572825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004212","name":"P\u00e4ivikki ja Sakari Sohlbergin S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004212","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biomechanics"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.jbiomech.2019.109450","type":"journal-article","created":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T19:43:00Z","timestamp":1571859780000},"page":"109450","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Anterior cruciate ligament transection of rabbits alters composition, structure and biomechanics of articular cartilage and chondrocyte deformation 2\u202fweeks post-surgery in a site-specific manner"],"prefix":"10.1016","volume":"98","author":[{"given":"Simo P.","family":"Ojanen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikko A.J.","family":"Finnil\u00e4","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janne T.A.","family":"M\u00e4kel\u00e4","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiira","family":"Saarela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilia","family":"Happonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Herzog","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2850-5484","authenticated-orcid":false,"given":"Simo","family":"Saarakkala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rami K.","family":"Korhonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbiomech.2019.109450_b0005","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1115\/1.1579047","article-title":"Alterations in the mechanical properties of the human chondrocyte pericellular matrix with osteoarthritis","volume":"125","author":"Alexopoulos","year":"2003","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.jbiomech.2019.109450_b0010","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0049-0172(90)90081-P","article-title":"Osteoarthritis research: animal models","volume":"19","author":"Altman","year":"1990","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.jbiomech.2019.109450_b0015","first-page":"245","article-title":"The short-term compressive properties of adult human articular cartilage","volume":"4","author":"Bader","year":"1994","journal-title":"Biomed. Mater. Eng."},{"key":"10.1016\/j.jbiomech.2019.109450_b0020","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0304-4165(92)90111-7","article-title":"The effects of selective matrix degradation on the short-term compressive properties of adult human articular cartilage","volume":"1116","author":"Bader","year":"1992","journal-title":"BBA \u2013 Gen. Subj."},{"key":"10.1016\/j.jbiomech.2019.109450_b0025","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1007\/s00216-006-0910-7","article-title":"Fourier transform infrared imaging and MR microscopy studies detect compositional and structural changes in cartilage in a rabbit model of osteoarthritis","volume":"387","author":"Bi","year":"2007","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.jbiomech.2019.109450_b0030","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/jor.1100100202","article-title":"The early effects of joint immobilization on medial collateral ligament healing in an ACL-deficient knee: a gross anatomic and biomechanical investigation in the adult rabbit model","volume":"10","author":"Bray","year":"1992","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2019.109450_b0035","first-page":"465","article-title":"Articular cartilage and osteoarthritis","volume":"54","author":"Buckwalter","year":"2005","journal-title":"Instr. Course Lect."},{"key":"10.1016\/j.jbiomech.2019.109450_b0040","first-page":"487","article-title":"Articular cartilage Part II: degeneration and osteoarthritis, repair, regeneration, and transplantation","volume":"47","author":"Buckwalter","year":"1998","journal-title":"Instr. Course Lect."},{"issue":"Pt 4","key":"10.1016\/j.jbiomech.2019.109450_b0045","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1242\/jcs.108.4.1497","article-title":"Mechanical compression modulates matrix biosynthesis in chondrocyte\/agarose culture","volume":"108","author":"Buschmann","year":"1995","journal-title":"J. Cell Sci."},{"issue":"Pt 2","key":"10.1016\/j.jbiomech.2019.109450_b0050","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1242\/jcs.109.2.499","article-title":"Altered aggrecan synthesis correlates with cell and nucleus structure in statically compressed cartilage","volume":"109","author":"Buschmann","year":"1996","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.jbiomech.2019.109450_b0055","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/S1063-4584(02)00369-2","article-title":"The volume and morphology of chondrocytes within non-degenerate and degenerate human articular cartilage","volume":"11","author":"Bush","year":"2003","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2019.109450_b0060","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/S0736-0266(01)00013-4","article-title":"The osmotic sensitivity of isolated and in situ bovine articular chondrocytes","volume":"19","author":"Bush","year":"2001","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2019.109450_b0065","doi-asserted-by":"crossref","first-page":"392","DOI":"10.2106\/00004623-197557030-00018","article-title":"Biochemical confirmation of an experimental osteoarthritis model","volume":"57","author":"Ehrlich","year":"1975","journal-title":"J. Bone Jt. Surg. - Ser. A"},{"key":"10.1016\/j.jbiomech.2019.109450_b0070","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1042\/bj1880823","article-title":"Biosynthesis of collagen and other matrix proteins by articular cartilage in experimental osteoarthrosis","volume":"188","author":"Eyre","year":"1980","journal-title":"Biochem. J."},{"key":"10.1016\/j.jbiomech.2019.109450_b0075","doi-asserted-by":"crossref","first-page":"4010","DOI":"10.1016\/j.jbiomech.2015.09.049","article-title":"Site-dependent biomechanical responses of chondrocytes in the rabbit knee joint","volume":"48","author":"Fick","year":"2015","journal-title":"J. Biomech."},{"issue":"16","key":"10.1016\/j.jbiomech.2019.109450_bib316","doi-asserted-by":"crossref","first-page":"4057","DOI":"10.1016\/j.jbiomech.2016.10.039","article-title":"Early in situ changes in chondrocyte biomechanical responses due to a partial meniscectomy in the lateral compartment of the mature rabbit knee joint","volume":"49","author":"Fick","year":"2016","journal-title":"Journal of Biomechanics"},{"key":"10.1016\/j.jbiomech.2019.109450_b0085","doi-asserted-by":"crossref","first-page":"S67","DOI":"10.1016\/j.joca.2017.02.122","article-title":"Increased cartilage remodelling and impaired chondrocyte mechanotransduction in early post-traumatic osteoartritis","volume":"25","author":"Finnil\u00e4","year":"2017","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2019.109450_b0090","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1093\/rheumatology\/keg094","article-title":"Moderate-impact exercise is associated with decreased severity of experimental osteoarthritis in rats","volume":"42","author":"Galois","year":"2003","journal-title":"Rheumatology"},{"key":"10.1016\/j.jbiomech.2019.109450_b0095","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/jor.1100120404","article-title":"Anonymous Mechanical and biochemical changes in the superficial zone of articular cartilage in canine experimental osteoarthritis","volume":"12","author":"Guilak","year":"1994","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2019.109450_b0105","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1098\/rsif.2009.0458","article-title":"Mechanical loading of in situ chondrocytes in lapine retropatellar cartilage after anterior cruciate ligament transection","volume":"7","author":"Han","year":"2010","journal-title":"J. R. Soc. Interface"},{"key":"10.1016\/j.jbiomech.2019.109450_b0110","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/j.medengphy.2009.05.013","article-title":"Confocal microscopy indentation system for studying in situ chondrocyte mechanics","volume":"31","author":"Han","year":"2009","journal-title":"Med. Eng. Phys."},{"key":"10.1016\/j.jbiomech.2019.109450_b0115","article-title":"Alterations in structural macromolecules and chondrocyte deformations in lapine retropatellar cartilage 9 weeks after anterior cruciate ligament transection","volume":"1\u20139","author":"Han","year":"2017","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2019.109450_b0120","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0021-9290(97)00119-X","article-title":"In vivo knee joint loading and kinematics before and after ACL transection in an animal model","volume":"31","author":"Hasler","year":"1997","journal-title":"J. Biomech."},{"key":"10.1016\/j.jbiomech.2019.109450_b0125","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0021-9290(97)00105-X","article-title":"Quantification of in vivo patellofemoral contact forces before and after ACE transection","volume":"31","author":"Hasler","year":"1997","journal-title":"J. Biomech."},{"key":"10.1016\/j.jbiomech.2019.109450_b0130","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.bone.2005.08.007","article-title":"Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis","volume":"38","author":"Hayami","year":"2006","journal-title":"Bone"},{"key":"10.1016\/j.jbiomech.2019.109450_b0135","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/0021-9290(72)90010-3","article-title":"A mathematical analysis for indentation test of articular cartilage","volume":"5","author":"Hayes","year":"1972","journal-title":"J. Biomech."},{"key":"10.1016\/j.jbiomech.2019.109450_b0140","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/S0021-9290(98)00136-5","article-title":"Material and functional properties of articular cartilage and patellofemoral contact mechanics in an experimental model of osteoarthritis","volume":"31","author":"Herzog","year":"1998","journal-title":"J. Biomech."},{"key":"10.1016\/j.jbiomech.2019.109450_b0145","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF02331414","article-title":"Safranin O reduces loss of glycosaminoglycans from bovine articular cartilage during histological specimen preparation","volume":"28","author":"Kir\u00e1ly","year":"1996","journal-title":"Histochem. J."},{"key":"10.1016\/j.jbiomech.2019.109450_b0150","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/BF02331378","article-title":"Application of selected cationic dyes for the semiquantitative estimation of glycosaminoglycans in histological sections of articular cartilage by microspectrophotometry","volume":"28","author":"Kir\u00e1ly","year":"1996","journal-title":"Histochem. J."},{"key":"10.1016\/j.jbiomech.2019.109450_b0155","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/BF00501401","article-title":"Microspectrophotometric quantitation of glycosaminoglycans in articular cartilage sections stained with Safranin O","volume":"82","author":"Kiviranta","year":"1985","journal-title":"Histochemistry"},{"key":"10.1016\/j.jbiomech.2019.109450_b0160","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1002\/jor.20107","article-title":"Collagen network primarily controls poisson\u2019s ratio of bovine articular cartilage in compression","volume":"24","author":"Kiviranta","year":"2006","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2019.109450_b0165","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/S0021-9290(02)00052-0","article-title":"Comparison of the equilibrium response of articular cartilage in unconfined compression, confined compression and indentation","volume":"35","author":"Korhonen","year":"2002","journal-title":"J. Biomech."},{"key":"10.1016\/j.jbiomech.2019.109450_b0170","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.jbiomech.2007.09.002","article-title":"Depth-dependent analysis of the role of collagen fibrils, fixed charges and fluid in the pericellular matrix of articular cartilage on chondrocyte mechanics","volume":"41","author":"Korhonen","year":"2008","journal-title":"J. Biomech."},{"key":"10.1016\/j.jbiomech.2019.109450_b0175","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/S0021-9290(03)00069-1","article-title":"Fibril reinforced poroelastic model predicts specifically mechanical behavior of normal, proteoglycan depleted and collagen degraded articular cartilage","volume":"36","author":"Korhonen","year":"2003","journal-title":"J. Biomech."},{"key":"10.1016\/j.jbiomech.2019.109450_b0180","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.2106\/00004623-200608000-00020","article-title":"Anterior cruciate ligament deficiency alters the in vivo motion of the tibiofemoral cartilage contact points in both the anteroposterior and mediolateral directions","volume":"88","author":"Li","year":"2006","journal-title":"J. Bone Jt. Surg. - Ser. A"},{"key":"10.1016\/j.jbiomech.2019.109450_b0185","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.joca.2014.04.010","article-title":"Site-dependent changes in structure and function of lapine articular cartilage 4 weeks after anterior cruciate ligament transection","volume":"22","author":"M\u00e4kel\u00e4","year":"2014","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2019.109450_b0190","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1053\/joca.2001.0491","article-title":"The canine \u201cgroove\u201d model, compared with the ACLT model of osteoarthritis","volume":"10","author":"Marijnissen","year":"2002","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2019.109450_b0195","unstructured":"McCulloch, C.E., Searle, S.R. (Shayle R.., Neuhaus, J.M., 2008. Generalized, linear, and mixed models, 2nd ed. ed, Wiley series in probability and statistics. Wiley."},{"key":"10.1016\/j.jbiomech.2019.109450_b0200","doi-asserted-by":"crossref","DOI":"10.1302\/0301-620X.58B1.131804","article-title":"Biochemical changes in the cartilage of the knee in experimental and natural osteoarthritis in the dog","volume":"58-B","author":"McDevitt","year":"1976","journal-title":"J. Bone Jt. Surg."},{"key":"10.1016\/j.jbiomech.2019.109450_b0210","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1002\/anr.1780320913","article-title":"Gait alterations in dogs after transection of the anterior cruciate ligament","volume":"32","author":"O\u2019connor","year":"1989","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jbiomech.2019.109450_b0215","doi-asserted-by":"crossref","first-page":"e0196203","DOI":"10.1371\/journal.pone.0196203","article-title":"Site-specific glycosaminoglycan content is better maintained in the pericellular matrix than the extracellular matrix in early post-traumatic osteoarthritis","volume":"13","author":"Ojanen","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.jbiomech.2019.109450_b0220","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1177\/0363546511423380","article-title":"Cartilage injury after acute, isolated anterior cruciate ligament tear","volume":"40","author":"Potter","year":"2012","journal-title":"Am. J. Sports Med."},{"key":"10.1016\/j.jbiomech.2019.109450_b0225","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/jemt.20551","article-title":"Practical considerations in the use of polarized light microscopy in the analysis of the collagen network in articular cartilage","volume":"71","author":"Rieppo","year":"2008","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.jbiomech.2019.109450_b0230","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.joca.2008.09.004","article-title":"Changes in spatial collagen content and collagen network architecture in porcine articular cartilage during growth and maturation","volume":"17","author":"Rieppo","year":"2009","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2019.109450_b0235","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1159\/000074628","article-title":"Structure-function relationships in enzymatically modified articular cartilage","volume":"175","author":"Rieppo","year":"2003","journal-title":"Cells Tissues Organs"},{"key":"10.1016\/j.jbiomech.2019.109450_b0240","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.1002\/art.27610","article-title":"Vulnerability of the superficial zone of immature articular cartilage to compressive injury","volume":"62","author":"Rolauffs","year":"2010","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.jbiomech.2019.109450_b0245","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/jor.1100150207","article-title":"Physical properties of rabbit articular cartilage after transection of the anterior cruciate ligament","volume":"15","author":"Sah","year":"1997","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2019.109450_b0250","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/jor.1100040402","article-title":"Effects of mechanical and osmotic pressure on the rate of glycosaminoglycan synthesis in the human adult femoral head cartilage: an in vitro study","volume":"4","author":"Schneiderman","year":"1986","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2019.109450_b0255","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1053\/joca.1998.0170","article-title":"Altered mechanics of cartilage with osteoarthritis: Human osteoarthritis and an experimental model of joint degeneration","volume":"7","author":"Setton","year":"1999","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2019.109450_b0260","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/jor.1100130402","article-title":"Mechanical behavior of articular cartilage in shear is altered by transection of the anterior cruciate ligament","volume":"13","author":"Setton","year":"1995","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2019.109450_b0265","first-page":"425","article-title":"Ultrastructural changes in articular cartilage after experimental section of the anterior cruciate ligament of the dog knee","volume":"136","author":"Stockwell","year":"1983","journal-title":"J. Anat."},{"key":"10.1016\/j.jbiomech.2019.109450_b0270","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.joca.2004.08.004","article-title":"Chondrocyte mechanotransduction: Effects of compression on deformation of intracellular organelles and relevance to cellular biosynthesis","volume":"12","author":"Szafranski","year":"2004","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.jbiomech.2019.109450_b0275","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1155\/2013\/164146","article-title":"Superficial collagen fibril modulus and pericellular fixed charge density modulate chondrocyte volumetric behaviour in early osteoarthritis","volume":"2013","author":"Tanska","year":"2013","journal-title":"Comput. Math. Methods Med."},{"key":"10.1016\/j.jbiomech.2019.109450_b0280","doi-asserted-by":"crossref","first-page":"R262","DOI":"10.1186\/ar4107","article-title":"Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model","volume":"14","author":"Tsuchida","year":"2012","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.jbiomech.2019.109450_b0285","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.joca.2012.12.001","article-title":"Cell deformation behavior in mechanically loaded rabbit articular cartilage 4 weeks after anterior cruciate ligament transection","volume":"21","author":"Turunen","year":"2013","journal-title":"Osteoarthrit. Cartilage"},{"key":"10.1016\/j.jbiomech.2019.109450_b0295","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0304-4165(89)90050-0","article-title":"Regulation of proteoglycan synthesis rate in cartilage in vitro: influence of extracellular ionic composition","volume":"992","author":"Urban","year":"1989","journal-title":"BBA - Gen. Subj."},{"key":"10.1016\/j.jbiomech.2019.109450_b0300","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1002\/jcp.1041540208","article-title":"Regulation of matrix synthesis rates by the ionic and osmotic environment of articular chondrocytes","volume":"154","author":"Urban","year":"1993","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.jbiomech.2019.109450_b0310","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/jor.20027","article-title":"Causes of mechanically induced collagen damage in articular cartilage","volume":"24","author":"Wilson","year":"2006","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.jbiomech.2019.109450_b0315","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/jor.1100150206","article-title":"Chondrocyte biosynthesis correlates with local tissue strain in statically compressed adult articular cartilage","volume":"15","author":"Wong","year":"1997","journal-title":"J. Orthop. Res."}],"container-title":["Journal of Biomechanics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021929019306980?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021929019306980?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T01:24:58Z","timestamp":1758245098000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021929019306980"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":59,"alternative-id":["S0021929019306980"],"URL":"https:\/\/doi.org\/10.1016\/j.jbiomech.2019.109450","relation":{},"ISSN":["0021-9290"],"issn-type":[{"value":"0021-9290","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anterior cruciate ligament transection of rabbits alters composition, structure and biomechanics of articular cartilage and chondrocyte deformation 2\u202fweeks post-surgery in a site-specific manner","name":"articletitle","label":"Article Title"},{"value":"Journal of Biomechanics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jbiomech.2019.109450","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"109450"}}