{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:14Z","timestamp":1773273614476,"version":"3.50.1"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biotechnology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.jbiotec.2026.02.009","type":"journal-article","created":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T23:33:38Z","timestamp":1771716818000},"page":"51-60","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Development of efficient resin-based method for purifying 3-hydroxyphenazine-1-carboxylic acid from Aspergillus sclerotiorum ASJ82 crude extract"],"prefix":"10.1016","volume":"413","author":[{"given":"Malik","family":"Jan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1217-2827","authenticated-orcid":false,"given":"Kashif","family":"Hayat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Israr","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aadil Ahmed","family":"Memon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrar","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jbiotec.2026.02.009_bib1","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1007\/s10967-025-10031-3","article-title":"Investigation of adsorption isotherms and thermodynamic models of uranium biosorption from aqueous solutions by Rumex acetosella","volume":"334","author":"Alharbi","year":"2025","journal-title":"J. Radioanal. Nucl. Chem."},{"issue":"15","key":"10.1016\/j.jbiotec.2026.02.009_bib2","doi-asserted-by":"crossref","DOI":"10.1002\/jssc.202400372","article-title":"Macroporous polymeric resin for the purification of flavonoids from medicinal plants: a review","volume":"47","author":"Aljawarneh","year":"2024","journal-title":"J. Sep. Sci."},{"issue":"2-3","key":"10.1016\/j.jbiotec.2026.02.009_bib3","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jhazmat.2005.07.049","article-title":"Adsorption of acid dye onto organobentonite","volume":"128","author":"Baskaralingam","year":"2006","journal-title":"J. Hazard. Mater."},{"issue":"3","key":"10.1016\/j.jbiotec.2026.02.009_bib4","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1021\/je010325a","article-title":"Adsorption isotherms of Aspartame on commercial and chemically modified divinylbenzene\u2212 styrene resins at different temperatures","volume":"47","author":"Bautista","year":"2002","journal-title":"J. Chem. Eng. Data"},{"issue":"1","key":"10.1016\/j.jbiotec.2026.02.009_bib5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.29090\/psa.2018.01.029","article-title":"Preparative separation and purification of geniposide from Gardenia jasminoides ellis fruit using macroporous adsorption resin D101","volume":"42","author":"Bien","year":"2018","journal-title":"Pharm. Sci. Asia"},{"issue":"11","key":"10.1016\/j.jbiotec.2026.02.009_bib6","doi-asserted-by":"crossref","first-page":"3176","DOI":"10.1002\/jctb.5673","article-title":"Adsorption\/desorption characteristics, separation and purification of phenazine-1-carboxylic acid from fermentation extract by macroporous adsorbing resins","volume":"93","author":"Bilal","year":"2018","journal-title":"J. Chem. Technol. Biotechnol."},{"issue":"9","key":"10.1016\/j.jbiotec.2026.02.009_bib7","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1021\/jf205311v","article-title":"Adsorption and desorption properties of macroporous resins for anthocyanins from the calyx extract of roselle (Hibiscus sabdariffa L.)","volume":"60","author":"Chang","year":"2012","journal-title":"J. Agric. Food Chem."},{"issue":"4","key":"10.1016\/j.jbiotec.2026.02.009_bib8","doi-asserted-by":"crossref","first-page":"778","DOI":"10.3390\/molecules25040778","article-title":"Adsorption and desorption properties of total flavonoids from oil palm (Elaeis guineensis Jacq.) mature leaf on macroporous adsorption resins","volume":"25","author":"Che Zain M","year":"2020","journal-title":"Molecules"},{"issue":"1","key":"10.1016\/j.jbiotec.2026.02.009_bib9","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1038\/s41598-020-58335-6","article-title":"Isolation and characterization of nutrient dependent pyocyanin from Pseudomonas aeruginosa and its dye and agrochemical properties","volume":"10","author":"DeBritto","year":"2020","journal-title":"Sci. Rep."},{"issue":"1-2","key":"10.1016\/j.jbiotec.2026.02.009_bib10","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.chroma.2007.01.065","article-title":"Comparison of general rate model with a new model\u2014artificial neural network model in describing chromatographic kinetics of solanesol adsorption in packed column by macroporous resins","volume":"1145","author":"Du","year":"2007","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jbiotec.2026.02.009_bib11","first-page":"83183","article-title":"A simple and efficient preparative procedure for menaquinone-7 from Bacillus subtilis (natto) using two-stage extraction followed by microporous resins","author":"Fang","year":"2019","journal-title":"Process Biochem."},{"issue":"5","key":"10.1016\/j.jbiotec.2026.02.009_bib12","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1111\/1750-3841.14142","article-title":"Static, kinetic, and isotherm adsorption performances of macroporous adsorbent resins for recovery and enrichment of bioactive procyanidins from cranberry pomace","volume":"83","author":"Gao","year":"2018","journal-title":"J. Food Sci."},{"issue":"6","key":"10.1016\/j.jbiotec.2026.02.009_bib13","doi-asserted-by":"crossref","first-page":"3030","DOI":"10.1021\/jo5027707","article-title":"Synthesis, physical properties, and light-emitting diode performance of phenazine-based derivatives with three, five, and nine fused six-membered rings","volume":"80","author":"Gu","year":"2015","journal-title":"J. Org. Chem."},{"issue":"6","key":"10.1016\/j.jbiotec.2026.02.009_bib14","doi-asserted-by":"crossref","DOI":"10.1071\/EN25053","article-title":"Adsorption-based removal of PFASs from water: mechanisms, materials and future perspective","volume":"22","author":"Guo","year":"2025","journal-title":"Environ. Chem."},{"key":"10.1016\/j.jbiotec.2026.02.009_bib15","article-title":"Adsorption\/desorption characteristics and chromatographic purification of polyphenols from Vernonia patula (Dryand.) Merr. using macroporous adsorption resin","volume":"170113729","author":"Hou","year":"2021","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.jbiotec.2026.02.009_bib16","first-page":"1016607","article-title":"Production of trans-2, 3-dihydro-3-hydroxyanthranilic acid by engineered Pseudomonas chlororaphis GP72","author":"Hu","year":"2017","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"19","key":"10.1016\/j.jbiotec.2026.02.009_bib17","doi-asserted-by":"crossref","first-page":"4771","DOI":"10.3390\/molecules29194771","article-title":"Recent advances in phenazine natural products: chemical structures and biological activities","volume":"29","author":"Huang","year":"2024","journal-title":"Molecules"},{"issue":"6","key":"10.1016\/j.jbiotec.2026.02.009_bib18","doi-asserted-by":"crossref","first-page":"579","DOI":"10.3390\/fermentation9060579","article-title":"Aspergillus sclerotiorum whole-cell biocatalysis: a sustainable approach to produce 3-hydroxy-phenazine 1-carboxylic acid from phenazine 1-carboxylic acid","volume":"9","author":"Jan","year":"2023","journal-title":"Fermentation"},{"issue":"5","key":"10.1016\/j.jbiotec.2026.02.009_bib19","doi-asserted-by":"crossref","first-page":"3543","DOI":"10.1007\/s13399-021-01417-w","article-title":"A review on extractive fermentation via ion exchange adsorption resins opportunities, challenges, and future prospects","volume":"13","author":"Jatoi","year":"2023","journal-title":"Biomass. Convers. Biorefinery"},{"issue":"1-2","key":"10.1016\/j.jbiotec.2026.02.009_bib20","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0021-9673(01)00673-2","article-title":"Evaluation on the adsorption capabilities of new chemically modified polymeric adsorbents with protoporphyrin IX","volume":"917","author":"Jung","year":"2001","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jbiotec.2026.02.009_bib21","first-page":"143936","article-title":"Synthesis, biological evaluation, and metabolic stability of phenazine derivatives as antibacterial agents","author":"Krishnaiah","year":"2018","journal-title":"Eur. J. Med. Chem."},{"issue":"1-3","key":"10.1016\/j.jbiotec.2026.02.009_bib22","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0304-3894(00)00275-2","article-title":"Removal of phenols from aqueous solution by XAD-4 resin","volume":"80","author":"Ku","year":"2000","journal-title":"J. Hazard. Mater."},{"issue":"9","key":"10.1016\/j.jbiotec.2026.02.009_bib23","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1021\/ja02242a004","article-title":"The adsorption of gases on plane surfaces of glass, mica and platinum","volume":"40","author":"Langmuir","year":"1918","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jbiotec.2026.02.009_bib24","doi-asserted-by":"crossref","DOI":"10.1186\/s12934-016-0529-0","article-title":"Genetic engineering of Pseudomonas chlororaphis GP72 for the enhanced production of 2-hydroxyphenazine[J]","author":"Liu","year":"2016","journal-title":"Microb. Cell Factor."},{"issue":"15","key":"10.1016\/j.jbiotec.2026.02.009_bib25","doi-asserted-by":"crossref","first-page":"6077","DOI":"10.1016\/j.biortech.2010.03.019","article-title":"A simple method for the simultaneous decoloration and deproteinization of crude levan extract from Paenibacillus polymyxa EJS-3 by macroporous resin","volume":"101","author":"Liu","year":"2010","journal-title":"Bioresour. Technol."},{"issue":"2","key":"10.1016\/j.jbiotec.2026.02.009_bib26","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.talanta.2008.02.034","article-title":"Rapid quantitative analysis of phenazine-1-carboxylic acid and 2-hydroxyphenazine from fermentation culture of Pseudomonas chlororaphis GP72 by capillary zone electrophoresis","volume":"76","author":"Liu","year":"2008","journal-title":"Talanta"},{"issue":"17","key":"10.1016\/j.jbiotec.2026.02.009_bib27","doi-asserted-by":"crossref","first-page":"5267","DOI":"10.3390\/molecules26175267","article-title":"Effect of pore size distribution and amination on adsorption capacities of polymeric adsorbents","volume":"26","author":"Liu","year":"2021","journal-title":"Molecules"},{"issue":"12","key":"10.1016\/j.jbiotec.2026.02.009_bib28","doi-asserted-by":"crossref","first-page":"4667","DOI":"10.1016\/j.biortech.2010.01.058","article-title":"Preliminary enrichment and separation of genistein and apigenin from extracts of pigeon pea roots by macroporous resins","volume":"101","author":"Liu","year":"2010","journal-title":"Bioresour. Technol."},{"issue":"7","key":"10.1016\/j.jbiotec.2026.02.009_bib29","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.3390\/molecules30071478","article-title":"Analysis of macroporous resin combined extraction and purification of polyphenols from Agrimonia pilosa Ledeb. and anti-tumor effect in vitro","volume":"30","author":"Mei","year":"2025","journal-title":"Molecules"},{"issue":"7","key":"10.1016\/j.jbiotec.2026.02.009_bib30","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1021\/jf3036148","article-title":"Adsorption\/desorption characteristics and separation of anthocyanins from muscadine (Vitis rotundifolia) juice pomace by use of macroporous adsorbent resins","volume":"61","author":"Sandhu","year":"2013","journal-title":"J. Agric. Food Chem."},{"issue":"20","key":"10.1016\/j.jbiotec.2026.02.009_bib31","doi-asserted-by":"crossref","first-page":"3499","DOI":"10.1002\/elps.201000213","article-title":"Purification of low-concentration phenazine-1-carboxylic acid from fermentation broth of Pseudomonas sp. M18 via free flow electrophoresis with gratis gravity","volume":"31","author":"Shao","year":"2010","journal-title":"Electrophoresis"},{"issue":"2","key":"10.1016\/j.jbiotec.2026.02.009_bib32","doi-asserted-by":"crossref","DOI":"10.1002\/cssc.202401324","article-title":"Prospects of Pseudomonas in microbial fuel, bioremediation, and sustainability","volume":"18","author":"Song","year":"2025","journal-title":"ChemSusChem"},{"key":"10.1016\/j.jbiotec.2026.02.009_bib33","article-title":"Efficient direct preparation of antifungal Alteramide B from Lysobacter enzymogenes fermentation broth by macroporous resin adsorption","volume":"319124220","author":"Tang","year":"2021","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.jbiotec.2026.02.009_bib34","first-page":"987365","article-title":"Marine actinobacteria associated with marine organisms and their potentials in producing pharmaceutical natural products","author":"Valliappan","year":"2014","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.jbiotec.2026.02.009_bib35","series-title":"Pathogens Associated Development Cancer Humans OMICs Immunological Pathophysiological Studies","first-page":"369","article-title":"Natural compounds for inhibiting oncogenic microbiota: a review of their therapeutic applications","author":"Velez-Haro","year":"2024"},{"key":"10.1016\/j.jbiotec.2026.02.009_bib36","article-title":"Study on adsorption\/resolution properties, enrichment and purification of phenolic substances of Inonotus hispidus by macroporous adsorption resin","volume":"216118661","author":"Wang","year":"2024","journal-title":"Ind. Crops Prod."},{"issue":"2-3","key":"10.1016\/j.jbiotec.2026.02.009_bib37","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.cej.2011.06.075","article-title":"Resin adsorption as a means to enrich rare stilbenes and coumarin from pigeon pea leaves extracts","volume":"172","author":"Wei","year":"2011","journal-title":"Chem. Eng. J."},{"issue":"9","key":"10.1016\/j.jbiotec.2026.02.009_bib38","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1080\/01496395.2014.968263","article-title":"Equilibrium and kinetic studies on the adsorption of lignans from Schisandra chinensis by commercial macroporous resins","volume":"50","author":"Xu","year":"2015","journal-title":"Sep. Sci. Technol."},{"issue":"9","key":"10.1016\/j.jbiotec.2026.02.009_bib39","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1016\/S0045-6535(98)00413-5","article-title":"Adsorption of naphthalene derivatives on hypercrosslinked polymeric adsorbents","volume":"38","author":"Xu","year":"1999","journal-title":"Chemosphere"},{"issue":"11","key":"10.1016\/j.jbiotec.2026.02.009_bib40","doi-asserted-by":"crossref","first-page":"610","DOI":"10.3390\/md19110610","article-title":"Advances in phenazines over the past decade: Review of their pharmacological activities, mechanisms of action, biosynthetic pathways and synthetic strategies","volume":"19","author":"Yan","year":"2021","journal-title":"Mar. Drugs"},{"issue":"5","key":"10.1016\/j.jbiotec.2026.02.009_bib41","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1080\/10942912.2013.862632","article-title":"Purification of anthocyanins from extracts of red raspberry using macroporous resin","volume":"18","author":"Yang","year":"2015","journal-title":"Int. J. Food Prop."},{"key":"10.1016\/j.jbiotec.2026.02.009_bib42","first-page":"989122","article-title":"Preparative separation and purification of fumigaclavine C from fermented mycelia of Aspergillus fumigatus CY018 by macroporous adsorption resin","author":"Yao","year":"2015","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jbiotec.2026.02.009_bib43","first-page":"202144","article-title":"Development of an efficient method for separation and purification of trans-2, 3-dihydro-3-hydroxyanthranilic acid from Pseudomonas chlororaphis GP72 fermentation broth","author":"Yue","year":"2018","journal-title":"Sep. Purif. Technol."},{"key":"10.1016\/j.jbiotec.2026.02.009_bib44","first-page":"2969","article-title":"Adsorption\/desorption characteristics and enrichment of quercetin, luteolin and apigenin from Flos populi using macroporous resin","author":"Zhang","year":"2019","journal-title":"Rev. Bras. De. Farmacogn."},{"key":"10.1016\/j.jbiotec.2026.02.009_bib45","first-page":"2831522","article-title":"A comparative study on the adsorption of 8-amino-1-naphthol-3, 6-disulfonic acid by a macroporous amination resin","author":"Zhang","year":"2016","journal-title":"Chem. Eng. J."},{"issue":"4","key":"10.1016\/j.jbiotec.2026.02.009_bib46","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.fbp.2010.11.001","article-title":"Preliminary separation and purification of rutin and quercetin from Euonymus alatus (Thunb.) Siebold extracts by macroporous resins","volume":"89","author":"Zhao","year":"2011","journal-title":"Food Bioprod. Process."},{"issue":"2","key":"10.1016\/j.jbiotec.2026.02.009_bib47","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jfoodeng.2010.04.011","article-title":"Extraction of sesamin from sesame oil using macroporous resin","volume":"100","author":"Zhou","year":"2010","journal-title":"J. Food Eng."},{"key":"10.1016\/j.jbiotec.2026.02.009_bib48","first-page":"1","article-title":"Phenazines contribute to microbiome dynamics by targeting topoisomerase IV","author":"Zhou","year":"2025","journal-title":"Nat. Microbiol."}],"container-title":["Journal of Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168165626000593?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168165626000593?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T09:30:28Z","timestamp":1773221428000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168165626000593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":48,"alternative-id":["S0168165626000593"],"URL":"https:\/\/doi.org\/10.1016\/j.jbiotec.2026.02.009","relation":{},"ISSN":["0168-1656"],"issn-type":[{"value":"0168-1656","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of efficient resin-based method for purifying 3-hydroxyphenazine-1-carboxylic acid from Aspergillus sclerotiorum ASJ82 crude extract","name":"articletitle","label":"Article Title"},{"value":"Journal of Biotechnology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jbiotec.2026.02.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}