{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T16:59:25Z","timestamp":1780937965430,"version":"3.54.1"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bodyworkmovementtherapies.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Bodywork and Movement Therapies"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.jbmt.2026.03.026","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T16:35:54Z","timestamp":1774283754000},"page":"186-190","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Paravertebral intramuscular and rectal insufflation oxygen-ozone therapy for modic 1- related low back pain: a case report"],"prefix":"10.1016","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2603-5220","authenticated-orcid":false,"given":"Valeria","family":"Fiaschetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9900-4725","authenticated-orcid":false,"given":"Nicola","family":"Manocchio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helga","family":"Cosolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Dell\u2019Anna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Porcari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Di Roma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Dell\u2019 Anna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2246-348X","authenticated-orcid":false,"given":"Calogero","family":"Foti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbmt.2026.03.026_bib1","doi-asserted-by":"crossref","first-page":"425","DOI":"10.2519\/jospt.2022.10788","article-title":"Medications for treating low back pain in adults. Evidence for the use of paracetamol, opioids, nonsteroidal anti-inflammatories, muscle relaxants, antibiotics, and antidepressants: an overview for musculoskeletal Clinicians","volume":"52","author":"Anderson","year":"2022","journal-title":"J. Orthop. Sports Phys. Ther."},{"key":"10.1016\/j.jbmt.2026.03.026_bib2","first-page":"41","article-title":"Intramuscular oxygen-ozone therapy in the treatment of low back pain","volume":"89","author":"Biazzo","year":"2018","journal-title":"Acta Bio Medica Atenei Parm"},{"key":"10.1016\/j.jbmt.2026.03.026_bib3","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1177\/1591019917703784","article-title":"MRI findings in lumbar spine following O2\u2013O3 chemiodiscolysis: a long-term follow-up","volume":"23","author":"Bruno","year":"2017","journal-title":"Intervent Neuroradiol."},{"key":"10.1016\/j.jbmt.2026.03.026_bib4","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1186\/s13018-023-03839-w","article-title":"Modic changes as seen on MRI are associated with nonspecific chronic lower back pain and disability","volume":"18","author":"Czaplewski","year":"2023","journal-title":"J. Orthop. Surg."},{"key":"10.1016\/j.jbmt.2026.03.026_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.111596","article-title":"Ozone therapy (O2-O3) alleviates the progression of early intervertebral disc degeneration via the inhibition of oxidative stress and the interception of the PI3K\/Akt\/NF-\u03baB signaling pathway","volume":"129","author":"Elmounedi","year":"2024","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jbmt.2026.03.026_bib6","author":"Espeland"},{"key":"10.1016\/j.jbmt.2026.03.026_bib7","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242417175","article-title":"Modifications of blood molecular components after treatment with low ozone concentrations","volume":"24","author":"Inguscio","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jbmt.2026.03.026_bib8","doi-asserted-by":"crossref","first-page":"6","DOI":"10.4103\/2045-9912.374388","article-title":"Intramuscular paravertebral oxygen-ozone therapy for chronic neck pain and low back pain: evaluation of 6-month clinical outcomes","volume":"14","author":"Latini","year":"2024","journal-title":"Med. Gas Res."},{"key":"10.1016\/j.jbmt.2026.03.026_bib9","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.3390\/life14111406","article-title":"The effectiveness of ozone infiltration on patient-reported outcomes in low back pain: a systematic review and meta-analysis","volume":"14","author":"Llombart-Blanco","year":"2024","journal-title":"Life"},{"key":"10.1016\/j.jbmt.2026.03.026_bib10","doi-asserted-by":"crossref","DOI":"10.3390\/ijms252312657","article-title":"Low-dose ozone as a eustress inducer: experimental evidence of the molecular mechanisms accounting for its therapeutic action","volume":"25","author":"Malatesta","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jbmt.2026.03.026_bib11","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s00068-025-02788-9","article-title":"Impact of education in patients undergoing physiotherapy for lower back pain: a level I systematic review and meta-analysis","volume":"51","author":"Migliorini","year":"2025","journal-title":"Eur. J. Trauma Emerg. Surg."},{"key":"10.1016\/j.jbmt.2026.03.026_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2022.e09658","article-title":"Non-surgical therapy for the treatment of chronic low back pain in patients with Modic changes: a systematic review of the literature","volume":"8","author":"Mu","year":"2022","journal-title":"Heliyon"},{"key":"10.1016\/j.jbmt.2026.03.026_bib14","article-title":"Madrid declaration on ozone therapy","author":"Schwartz","year":"2020","journal-title":"Int. Sci. Comm. Ozone Ther."},{"key":"10.1016\/j.jbmt.2026.03.026_bib15","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.ajic.2007.10.021","article-title":"Ozone gas is an effective and practical antibacterial agent","volume":"36","author":"Sharma","year":"2008","journal-title":"Am. J. Infect. Control"},{"key":"10.1016\/j.jbmt.2026.03.026_bib13","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1111\/papr.12812","article-title":"The effect of paravertebral ozone injection in the treatment of low back pain","volume":"19","author":"\u00d6zcan","year":"2019","journal-title":"Pain Pract."},{"key":"10.1016\/j.jbmt.2026.03.026_bib16","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.7150\/ijbs.41940","article-title":"Ozone therapy attenuates NF-\u03baB-Mediated local inflammatory response and activation of Th17 cells in treatment for psoriasis","volume":"16","author":"Zeng","year":"2020","journal-title":"Int. J. Biol. Sci."}],"container-title":["Journal of Bodywork and Movement Therapies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S136085922600032X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S136085922600032X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T16:12:34Z","timestamp":1780935154000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S136085922600032X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":16,"alternative-id":["S136085922600032X"],"URL":"https:\/\/doi.org\/10.1016\/j.jbmt.2026.03.026","relation":{},"ISSN":["1360-8592"],"issn-type":[{"value":"1360-8592","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Paravertebral intramuscular and rectal insufflation oxygen-ozone therapy for modic 1- related low back pain: a case report","name":"articletitle","label":"Article Title"},{"value":"Journal of Bodywork and Movement Therapies","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jbmt.2026.03.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}