{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T06:14:14Z","timestamp":1793513654707,"version":"4.5.0"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T00:00:00Z","timestamp":1657065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Bone Oncology"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.jbo.2022.100446","type":"journal-article","created":{"date-parts":[[2022,7,9]],"date-time":"2022-07-09T11:58:14Z","timestamp":1657367894000},"page":"100446","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":203,"special_numbering":"C","title":["Epidemiology of spinal metastases, metastatic epidural spinal cord compression and pathologic vertebral compression fractures in patients with solid tumors: A systematic review"],"prefix":"10.1016","volume":"35","author":[{"given":"Ruben","family":"Van den Brande","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erwin","family":"MJ Cornips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Peeters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piet","family":"Ost","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Billiet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Van de Kelft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbo.2022.100446_b0005","unstructured":"World Health Organization. Who Report on Cancer: Setting Priorities, Investing Wesely and Providing Care for All.; 2020."},{"issue":"10125","key":"10.1016\/j.jbo.2022.100446_b0010","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0140-6736(17)33326-3","article-title":"Global surveillance of trends in cancer survival: analysis of individual records for 37,513,025 patients diagnosed with one of 18 cncers during 2000\u20132014 from 322 populatio-based registries in 71 countries (CONCORD-3)","volume":"391","author":"Allemani","year":"2018","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.jbo.2022.100446_b0015","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/pon.3846","article-title":"The longitudinal relationship between quality of life and survival in advanced stage cancer","volume":"25","author":"Kypriotakis","year":"2016","journal-title":"Psychooncology."},{"issue":"10","key":"10.1016\/j.jbo.2022.100446_b0020","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1038\/bjc.2014.208","article-title":"Does change in health-related quality of life score predict survival? Analysis of EORTC 08975 lung cancer trial","volume":"110","author":"Ediebah","year":"2014","journal-title":"Br. J. Cancer"},{"issue":"7","key":"10.1016\/j.jbo.2022.100446_b0025","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1002\/pon.5054","article-title":"Quality of life versus length of life considerations in cancer patients: A systematic literature review","volume":"28","author":"Shrestha","year":"2019","journal-title":"Psycho-Oncology"},{"key":"10.1016\/j.jbo.2022.100446_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.wneu.2018.04.188","article-title":"Prognostic factors of ambulatory status for patients with metastatic spinal cord compression: a systematic review and meta-analysis","volume":"116","author":"Liu","year":"2018","journal-title":"World Neurosurg."},{"key":"10.1016\/j.jbo.2022.100446_b0035","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1007\/s00586-012-2635-y","article-title":"Effect of timing of surgery on neurological outcome and survival in metastatic spinal cord compression","volume":"22","author":"Quraishi","year":"2013","journal-title":"Eur. Spine J."},{"key":"10.1016\/j.jbo.2022.100446_b0040","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0140-6736(05)66954-1","article-title":"Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial","volume":"366","author":"Patchell","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.jbo.2022.100446_b0045","unstructured":"Fisher CG, Dipaola CP, Ryken TC, et al. A novel classification system for spinal instability in neoplastic disease: An evidence-based approach and expert consensus from the spine oncology study group. Spine (Phila Pa 1976). 2010;35(22):1221-12210.1097\/BRS.0b013e3181e16ae2."},{"issue":"2","key":"10.1016\/j.jbo.2022.100446_b0050","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1002\/1097-0142(197508)36:2<590::AID-CNCR2820360240>3.0.CO;2-F","article-title":"Metastases to the vertebral column","volume":"36","author":"Fornasier","year":"1975","journal-title":"Cancer"},{"key":"10.1016\/j.jbo.2022.100446_b0055","doi-asserted-by":"crossref","unstructured":"Wong DA, Fornasier VL, MacNab I. Spinal Metastases: The obvious, the occult and the impostors. Spine (Phila Pa 1976). 1990;15(1):1-4. http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=spinal+metastases:+the+obvious,+the+occult+and+the+imposters.","DOI":"10.1097\/00007632-199001000-00001"},{"key":"10.1016\/j.jbo.2022.100446_b0060","doi-asserted-by":"crossref","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. The BMJ. 2021;372. 10.1136\/bmj.n71.","DOI":"10.1136\/bmj.n71"},{"issue":"4","key":"10.1016\/j.jbo.2022.100446_b0065","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE)statement: guidelines for reporting observational studies","volume":"61","author":"von Elm","year":"2008","journal-title":"J. Clin. Epidemiol."},{"issue":"11","key":"10.1016\/j.jbo.2022.100446_b0070","doi-asserted-by":"crossref","first-page":"2334","DOI":"10.1002\/cncr.22678","article-title":"Economic burden of metastatic bone disease in the U.S","volume":"109","author":"Schulman","year":"2007","journal-title":"Cancer"},{"issue":"7","key":"10.1016\/j.jbo.2022.100446_b0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0234927","article-title":"Bone metastasis and skeletal-related events in patients with solid cancer: A Korean nationwide health insurance database study","volume":"15","author":"Hong","year":"2020","journal-title":"PLoS ONE"},{"issue":"3","key":"10.1016\/j.jbo.2022.100446_b0080","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.ijrobp.2010.03.022","article-title":"Incidence and treatment patterns in hospitalizations for malignant spinal cord compression in the United States, 1998\u20132006","volume":"80","author":"Mak","year":"2011","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.jbo.2022.100446_b0085","doi-asserted-by":"crossref","unstructured":"Choi SH, Koo JW, Choe D, Kang CN. The Incidence and Management Trends of Metastatic Spinal Tumors in South Korea: A Nationwide Population-based Study. Spine (Phila Pa 1976). 2020;45(14):E856-E863. 10.1097\/BRS.0000000000003445.","DOI":"10.1097\/BRS.0000000000003445"},{"issue":"12","key":"10.1016\/j.jbo.2022.100446_b0090","first-page":"3279","article-title":"Natural history of skeletal-related events in patients with breast, lung, or prostate cancer and metastases to bone: A 15-year study in two large US health systems","volume":"21","author":"Oster","year":"2013","journal-title":"Support. Care Cancer"},{"key":"10.1016\/j.jbo.2022.100446_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.canep.2020.101856","article-title":"Gender disparities in clinical presentation, treatment, and outcomes in metastatic spine disease","volume":"70","author":"Price","year":"2021","journal-title":"Cancer Epidemiol."},{"issue":"1","key":"10.1016\/j.jbo.2022.100446_b0100","doi-asserted-by":"crossref","DOI":"10.1186\/s12885-017-3922-0","article-title":"Incidence of bone metastases in patients with solid tumors: Analysis of oncology electronic medical records in the United States","volume":"18","author":"Hernandez","year":"2018","journal-title":"BMC Cancer."},{"issue":"5","key":"10.1016\/j.jbo.2022.100446_b0105","first-page":"309","article-title":"The incidence of vertebral body metastases","volume":"19","author":"Gomez","year":"1995","journal-title":"Int. Orthop."},{"key":"10.1016\/j.jbo.2022.100446_b0110","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.clon.2009.09.023","article-title":"A population-based study of spinal metastatic disease in south-east norway","volume":"21","author":"Zaikova","year":"2009","journal-title":"Clin. Oncol."},{"issue":"9","key":"10.1016\/j.jbo.2022.100446_b0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmjopen-2017-016022","article-title":"Survival after bone metastasis by primary cancer type: a Danish population-based cohort study","volume":"7","author":"Svensson","year":"2017","journal-title":"BMJ Open"},{"issue":"9","key":"10.1016\/j.jbo.2022.100446_b0120","first-page":"4335","article-title":"Prevalence and survival patterns of patients with bone metastasis from common cancers in Thailand","volume":"17","author":"Phanphaisarn","year":"2016","journal-title":"Asian Pac. J. Cancer Prev."},{"issue":"2","key":"10.1016\/j.jbo.2022.100446_b0125","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/nop\/npv006","article-title":"Nationwide epidemiology and healthcare utilization of spine tumor patients in the adult Korean population, 2009\u20132012","volume":"2","author":"Sohn","year":"2015","journal-title":"Neuro-Oncol. Pract."},{"key":"10.1016\/j.jbo.2022.100446_b0130","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.canep.2019.05.013","article-title":"Incidence of skeletal-related events in patients with breast or prostate cancer-induced bone metastasis or multiple myeloma: A 12-year longitudinal nationwide healthcare database study","volume":"61","author":"Baek","year":"2019","journal-title":"Cancer Epidemiol."},{"key":"10.1016\/j.jbo.2022.100446_b0135","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1471-2407-11-29","article-title":"Incidence of bone metastases and skeletal-related events in breast cancer patients: a population-based cohort study in Denmark","volume":"11","author":"Jensen","year":"2011","journal-title":"BMC Cancer"},{"issue":"1","key":"10.1016\/j.jbo.2022.100446_b0140","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00776-005-0966-9","article-title":"Incidence and prognostic factors of Japanese breast cancer patients with bone metastasis","volume":"11","author":"Oka","year":"2006","journal-title":"J. Orthopaedic Sci."},{"issue":"2","key":"10.1016\/j.jbo.2022.100446_b0145","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/1097-0142(20000715)89:2<363::AID-CNCR22>3.0.CO;2-3","article-title":"Predictors of skeletal complications patients with breast carcinoma","volume":"89","author":"Domchek","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.jbo.2022.100446_b0150","doi-asserted-by":"crossref","unstructured":"N\u00f8rgaard M, \u00d8stergaard Jensen A, Jacobsen JB, Cetin K, Fryzek JP, S\u00d8rensen HT. Skeletal Related Events, Bone Metastasis and Survival of Prostate Cancer: A Population Based Cohort Study in Denmark (1999 to 2007). The Journal of Urology. 2010;184:162-167.","DOI":"10.1016\/j.juro.2010.03.034"},{"issue":"2","key":"10.1016\/j.jbo.2022.100446_b0155","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.clon.2009.11.007","article-title":"Frequency of screening magnetic resonance imaging to detect occult spinal cord compromise and to prevent neurological deficit in metastatic castration-resistant prostate cancer","volume":"22","author":"Venkitaraman","year":"2010","journal-title":"Clin. Oncol."},{"key":"10.1016\/j.jbo.2022.100446_b0160","doi-asserted-by":"crossref","first-page":"307","DOI":"10.5489\/cuaj.2707","article-title":"Burden of illness of bone metastases in prostate cancer patients in Qu\u00e9bec, Canada: a population-based analysis","volume":"9","author":"Perrault","year":"2015","journal-title":"J. Can. Urol. Assoc."},{"issue":"6","key":"10.1016\/j.jbo.2022.100446_b0165","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.spinee.2015.02.015","article-title":"Incidence, associated factors, and survival in metastatic spinal cord compression secondary to lung cancer","volume":"15","author":"Silva","year":"2015","journal-title":"Spine J."},{"issue":"2","key":"10.1016\/j.jbo.2022.100446_b0170","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.lungcan.2015.04.007","article-title":"The incidence and clinical impact of bone metastases in non-small cell lung cancer","volume":"89","author":"Kuchuk","year":"2015","journal-title":"Lung Cancer"},{"issue":"2","key":"10.1016\/j.jbo.2022.100446_b0175","first-page":"231","article-title":"Prospective study on the incidence of infection by","volume":"9","author":"Katakami","year":"2014","journal-title":"J. Clin. Med."},{"issue":"2","key":"10.1016\/j.jbo.2022.100446_b0180","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.lungcan.2014.08.022","article-title":"Bone metastasis, skeletal-related events, and mortality in lung cancer patients: a Danish population-based cohort study","volume":"86","author":"Cetin","year":"2014","journal-title":"Lung Cancer."},{"key":"10.1016\/j.jbo.2022.100446_b0185","doi-asserted-by":"crossref","first-page":"363","DOI":"10.2147\/CLEP.S78301","article-title":"Hospital use among patients with lung cancer complicated by bone metastases and skeletal-related events: a population-based cohort study in Denmark","volume":"7","author":"Dalgaard","year":"2015","journal-title":"Clin. Epidemiol."},{"key":"10.1016\/j.jbo.2022.100446_b0190","doi-asserted-by":"crossref","unstructured":"Spiegel DA, Sampson JH, Richardson WJ, et al. Metastatic Melanoma to the Spine: Demographics, Risk Factors, and prognosis in 114 patients. Spine (Phila Pa 1976). 1995;20(19):2141-2146.","DOI":"10.1097\/00007632-199510000-00013"},{"issue":"4","key":"10.1016\/j.jbo.2022.100446_b0195","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s12029-017-9998-6","article-title":"hepatocellular carcinoma with bone metastases: incidence, prognostic significance, and management\u2014single-center experience","volume":"48","author":"Bhatia","year":"2017","journal-title":"J. Gastroint. Cancer"},{"issue":"1","key":"10.1016\/j.jbo.2022.100446_b0200","doi-asserted-by":"crossref","first-page":"50","DOI":"10.6004\/jnccn.2017.7024","article-title":"Frequency, morbidity, and mortality of bone metastases in advanced hepatocellular carcinoma","volume":"16","author":"Harding","year":"2018","journal-title":"JNCCN J. Natl. Comprehen. Cancer Netw."},{"issue":"9","key":"10.1016\/j.jbo.2022.100446_b0205","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1097\/00042737-200109000-00015","article-title":"Increased incidence of bone metastases in hepatocellular carcinoma","volume":"13","author":"Fukutomi","year":"2001","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"issue":"7","key":"10.1016\/j.jbo.2022.100446_b0210","first-page":"386","article-title":"Metastatic spinal cord compression: Incidence, epidemiology and prognostic factors","volume":"219","author":"Campillo-Recio","year":"2019","journal-title":"Rev. Cl\u00edn. Espa\u00f1ola (English Ed.)"},{"issue":"4","key":"10.1016\/j.jbo.2022.100446_b0215","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0936-6555(02)00400-4","article-title":"A population-based study of malignant spinal cord compression in Ontario","volume":"15","author":"Loblaw","year":"2003","journal-title":"Clin. Oncol."},{"issue":"2","key":"10.1016\/j.jbo.2022.100446_b0220","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s10549-011-1475-5","article-title":"Survival in breast cancer patients with bone metastases and skeletal-related events: a population-based cohort study in Denmark (1999\u20132007)","volume":"129","author":"Yong","year":"2011","journal-title":"Breast Cancer Res. Treat."},{"issue":"5","key":"10.1016\/j.jbo.2022.100446_b0225","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/0090-4295(86)90062-2","article-title":"Characteristics of spinal cord compression in adenocarcinoma of prostate","volume":"28","author":"Kuban","year":"1986","journal-title":"Urology"},{"key":"10.1016\/j.jbo.2022.100446_b0230","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/5971615","article-title":"Incidence of second primary malignancies in patients with castration-resistant prostate cancer: an observational retrospective cohort study in the United States","volume":"2019","author":"Kawai","year":"2019","journal-title":"Prostate Cancer"},{"issue":"3","key":"10.1016\/j.jbo.2022.100446_b0235","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jgo.2014.03.002","article-title":"Skeletal-related events and mortality among older men with advanced prostate cancer","volume":"5","author":"Onukwugha","year":"2014","journal-title":"J. Geriat. Oncol."},{"issue":"4","key":"10.1016\/j.jbo.2022.100446_b0240","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1016\/S0022-5347(05)67149-2","article-title":"Incidence of skeletal complications in patients with bone metastatic prostate cancer and hormone refractory disease: predictive role of bone resorption and formation markers evaluated at baseline","volume":"164","author":"Berruti","year":"2000","journal-title":"J. Urol."},{"key":"10.1016\/j.jbo.2022.100446_b0245","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.wneu.2017.09.079","article-title":"Impact of symptomatic metastatic spinal cord compression on survival of patients with non-small-cell lung cancer","volume":"108","author":"da Silva","year":"2017","journal-title":"World Neurosurgery."},{"issue":"1","key":"10.1016\/j.jbo.2022.100446_b0250","doi-asserted-by":"crossref","DOI":"10.1186\/s40064-016-2097-5","article-title":"Vertebral body fractures of unknown origin in cancer patients receiving MDCT: reporting by radiologists and awareness by clinicians","volume":"5","author":"Wild","year":"2016","journal-title":"Springerplus"},{"issue":"3","key":"10.1016\/j.jbo.2022.100446_b0255","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1097\/JTO.0b013e318206a1e3","article-title":"Epidemiology and treatment costs of bone metastases from lung cancer: A French prospective, observational, multicenter study (GFPC 0601)","volume":"6","author":"Decroisette","year":"2011","journal-title":"J. Thor. Oncol."},{"issue":"1\u20132","key":"10.1016\/j.jbo.2022.100446_b0260","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BF01402610","article-title":"Metastatic spinal cord compression - Occurrence, symptoms, clinical presentations and prognosis in 398 patients with spinal cord compression","volume":"107","author":"Bach","year":"1990","journal-title":"Acta Neurochir."},{"issue":"12","key":"10.1016\/j.jbo.2022.100446_b0265","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1002\/cncr.20308","article-title":"Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, phase III, double-blind, placebo-controlled trial","volume":"100","author":"Rosen","year":"2004","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.jbo.2022.100446_b0270","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1001\/jama.2016.19425","article-title":"Effect of longer-interval vs standard dosing of zoledronic acid on skeletal events in patients with bone metastases: a randomized clinical trial","volume":"317","author":"Himelstein","year":"2017","journal-title":"JAMA Oncol."},{"issue":"15","key":"10.1016\/j.jbo.2022.100446_b0275","doi-asserted-by":"crossref","first-page":"3314","DOI":"10.1200\/JCO.2005.05.116","article-title":"Zoledronic acid significantly reduces skeletal complications compared with placebo in Japanese women with bone metastases from breast cancer: a randomized, placebo-controlled trial","volume":"23","author":"Kohno","year":"2005","journal-title":"J. Clin. Oncol."},{"issue":"3","key":"10.1016\/j.jbo.2022.100446_b0280","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1200\/JCO.1999.17.3.846","article-title":"Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: a randomized Placebo-Controlled Trial","volume":"17","author":"Theriault","year":"1999","journal-title":"J. Clin. Oncol."},{"issue":"17","key":"10.1016\/j.jbo.2022.100446_b0285","doi-asserted-by":"crossref","first-page":"4841","DOI":"10.1158\/1078-0432.CCR-11-3310","article-title":"Bone-related complications and quality of life in advanced breast cancer: Results from a randomized phase III trial of denosumab versus zoledronic acid","volume":"18","author":"Martin","year":"2012","journal-title":"Clin. Cancer Res."},{"issue":"4","key":"10.1016\/j.jbo.2022.100446_b0290","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1001\/jamaoncol.2015.5570","article-title":"Clinical outcomes and survival following treatment of metastatic castrate-refractory prostate cancer with docetaxel alone or with strontium-89, zoledronic acid, or both: The TRAPEZE randomized clinical trial","volume":"2","author":"James","year":"2016","journal-title":"JAMA Oncol."},{"issue":"23","key":"10.1016\/j.jbo.2022.100446_b0295","doi-asserted-by":"crossref","first-page":"4277","DOI":"10.1200\/JCO.2003.05.147","article-title":"Combined analysis of two multicenter, randomized, placebo-controlled studies of pamidronate disodium for the palliation of bone pain in men with metastatic prostate cancer","volume":"21","author":"Small","year":"2003","journal-title":"J. Clin. Oncol."},{"issue":"17","key":"10.1016\/j.jbo.2022.100446_b0300","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1093\/jnci\/djg038","article-title":"A double-blind, placebo-controlled, randomized trial of oral sodium clodronate for metastatic prostate cancer (MRC PR05 Trial)","volume":"95","author":"Dearnaley","year":"2003","journal-title":"J. Natl. Cancer Inst."},{"issue":"11","key":"10.1016\/j.jbo.2022.100446_b0305","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1093\/jnci\/djh141","article-title":"Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer","volume":"96","author":"Saad","year":"2004","journal-title":"J. Natl Cancer Inst."},{"issue":"9768","key":"10.1016\/j.jbo.2022.100446_b0310","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/S0140-6736(10)62344-6","article-title":"Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study","volume":"377","author":"Fizazi","year":"2011","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.jbo.2022.100446_b0315","doi-asserted-by":"crossref","DOI":"10.1007\/s12032-013-0657-x","article-title":"Comparison between zoledronic acid and clodronate in the treatment of prostate cancer patients with bone metastases","volume":"30","author":"Wang","year":"2013","journal-title":"Med. Oncol."},{"key":"10.1016\/j.jbo.2022.100446_b0320","first-page":"3837","article-title":"Efficacy of combined androgen blockade with zoledronic acid treatment in prostate cancer with bone metastasis: the ZABTON-PC (Zoledronic Acid\/androgen bloackade trial on prostate cancer) study","volume":"33","author":"Ueno","year":"2003","journal-title":"Anticancer Res."},{"issue":"12","key":"10.1016\/j.jbo.2022.100446_b0325","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1007\/s11255-014-0824-9","article-title":"Docetaxel with or without zoledronic acid for castration-resistant prostate cancer","volume":"46","author":"Pan","year":"2014","journal-title":"Int. Urol. Nephrol."},{"issue":"6","key":"10.1016\/j.jbo.2022.100446_b0330","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1007\/s00432-017-2350-5","article-title":"Impact of denosumab use on the survival of untreated non-squamous non-small cell lung cancer patients with bone metastases","volume":"143","author":"Udagawa","year":"2017","journal-title":"J. Cancer Res. Clin. Oncol."},{"issue":"2","key":"10.1016\/j.jbo.2022.100446_b0335","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/jpm11020110","article-title":"Management of metastatic spinal cord compression in secondary care: a practice reflection from medway maritime hospital, Kent, UK","volume":"11","author":"Shah","year":"2021","journal-title":"J. Personal. Med."},{"issue":"3","key":"10.1016\/j.jbo.2022.100446_b0340","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/0959-8049(94)90263-1","article-title":"Symptoms and signs in metastatic spinal cord compression: a study of progression from first symptom until diagnosis in 153 patients","volume":"30","author":"Helweg-Larsen","year":"1994","journal-title":"Eur. J. Cancer"},{"issue":"6","key":"10.1016\/j.jbo.2022.100446_b0345","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1053\/clon.2002.0098","article-title":"Don\u2019t wait for a sensory level \u2013 Listen to the symptoms: a prospective audit of the delays in diagnosis of malignant cord compression","volume":"14","author":"Levack","year":"2002","journal-title":"Clin. Oncol."},{"issue":"October","key":"10.1016\/j.jbo.2022.100446_b0350","first-page":"1","article-title":"Are spine metastasis survival scoring systems outdated and do they underestimate life expectancy? Caution in surgical recommendation guidance","volume":"35","author":"Tabourel","year":"2021","journal-title":"J. Neurosurg. Spine"},{"key":"10.1016\/j.jbo.2022.100446_b0355","doi-asserted-by":"crossref","unstructured":"Carrwik C, Olerud C, Robinson Y. Predictive Scores Underestimate Survival of Patients with Metastatic Spine Disease: A Retrospective Study of 315 Patients in Sweden. Spine (Phila Pa 1976). 2020;45(6):414-419. 10.1097\/BRS.0000000000003289.","DOI":"10.1097\/BRS.0000000000003289"},{"key":"10.1016\/j.jbo.2022.100446_b0360","first-page":"65","article-title":"Outcome and toxicity of hypofractionated image-guided SABR for spinal oligometastases","volume":"24","author":"Billiet","year":"2020","journal-title":"Clin. Transl. Radiat. Oncol."},{"key":"10.1016\/j.jbo.2022.100446_b0365","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.radonc.2020.01.030","article-title":"Single fraction radiosurgery, fractionated radiosurgery, and conventional radiotherapy for spinal oligometastasis (SAFFRON): a systematic review and meta-analysis","volume":"146","author":"Singh","year":"2020","journal-title":"Radiother. Oncol."},{"issue":"7","key":"10.1016\/j.jbo.2022.100446_b0370","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S1470-2045(21)00196-0","article-title":"Stereotactic body radiotherapy versus conventional external beam radiotherapy in patients with painful spinal metastases: an open-label, multicentre, randomised, controlled, phase 2\/3 trial","volume":"22","author":"Sahgal","year":"2021","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.jbo.2022.100446_b0375","doi-asserted-by":"crossref","unstructured":"Hinojosa-Gonzalez DE, Roblesgil-Medrano A, Villarreal-Espinosa JB, et al. Minimally Invasive versus Open Surgery for Spinal Metastasis: A Systematic Review and Meta-Analysis. Asian Spine Journal. Published online 2021. 10.31616\/asj.2020.0637.","DOI":"10.31616\/asj.2021.0395.r2"}],"container-title":["Journal of Bone Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212137422000367?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212137422000367?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T20:20:07Z","timestamp":1761942007000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212137422000367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":75,"alternative-id":["S2212137422000367"],"URL":"https:\/\/doi.org\/10.1016\/j.jbo.2022.100446","relation":{},"ISSN":["2212-1374"],"issn-type":[{"value":"2212-1374","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epidemiology of spinal metastases, metastatic epidural spinal cord compression and pathologic vertebral compression fractures in patients with solid tumors: A systematic review","name":"articletitle","label":"Article Title"},{"value":"Journal of Bone Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jbo.2022.100446","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"100446"}}