{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T01:09:20Z","timestamp":1781831360354,"version":"3.54.5"},"reference-count":39,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Joint Bone Spine"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1016\/j.jbspin.2011.03.010","type":"journal-article","created":{"date-parts":[[2011,6,24]],"date-time":"2011-06-24T14:20:49Z","timestamp":1308925249000},"page":"63-66","source":"Crossref","is-referenced-by-count":24,"title":["Anti-mutated citrullinated vimentin (anti-MCV) and anti-65kDa heat shock protein (anti-hsp65): New biomarkers in ankylosing spondylitis"],"prefix":"10.1016","volume":"79","author":[{"given":"N\u00f3ra","family":"Bodn\u00e1r","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"Szekanecz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"Proh\u00e1szka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1d\u00e1m","family":"Kem\u00e9ny-Beke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsuzsanna","family":"N\u00e9methn\u00e9-Gyurcsik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katalin","family":"Guly\u00e1s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Lakos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e1ndor","family":"Sipka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e1ndor","family":"Sz\u00e1nt\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbspin.2011.03.010_bib0005","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.3748\/wjg.15.2449","article-title":"Clinical features and epidemiology of spondyloarthritides associated with inflammatory bowel disease","volume":"15","author":"Salvarani","year":"2009","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0010","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.jbspin.2009.02.006","article-title":"The genetic background of ankylosing spondylitis","volume":"76","author":"Vegvari","year":"2009","journal-title":"Joint Bone Spine"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0015","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1136\/ard.2009.108217","article-title":"The development of assessment of Spondylo Arthritis international Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal","volume":"68","author":"Rudwaleit","year":"2009","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0020","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1136\/ard.2007.073098","article-title":"MRI in predicting a major clinical response to anti-tumour necrosis factor treatment in ankylosing spondylitis","volume":"67","author":"Rudwaleit","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0025","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/s11926-007-0063-5","article-title":"Antibodies to citrullinated proteins: pathogenic and diagnostic significance","volume":"9","author":"Holers","year":"2007","journal-title":"Curr Rheumatol Rep"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0030","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s12016-007-8022-5","article-title":"Anti-citrullinated protein antibodies in rheumatoid arthritis: as good as it gets?","volume":"34","author":"Szekanecz","year":"2008","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0035","first-page":"1658","article-title":"Clinical evaluation of anti-mutated citrullinated vimentin by ELISA in rheumatoid arthritis","volume":"34","author":"Soos","year":"2007","journal-title":"J Rheumatol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0040","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/BOR.0b013e3282fbd22a","article-title":"Antibodies to citrullinated proteins in arthritis: pathology and promise","volume":"20","author":"Klareskog","year":"2008","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0045","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.autrev.2005.04.007","article-title":"The immune response to citrullinated antigens in autoimmune diseases","volume":"4","author":"Migliorini","year":"2005","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0050","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.jbspin.2004.07.004","article-title":"Clinical and pathophysiological significance of the autoimmune response to citrullinated proteins in rheumatoid arthritis","volume":"71","author":"Sebbag","year":"2004","journal-title":"Joint Bone Spine"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0055","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/rheumatology\/kep338","article-title":"New classification of the shared epitope in rheumatoid arthritis: impact on the production of various anti-citrullinated protein antibodies","volume":"49","author":"Gyetvai","year":"2010","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0060","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/art.24135","article-title":"Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region","volume":"60","author":"Ding","year":"2009","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0065","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/1529-0131(200001)43:1<155::AID-ANR20>3.0.CO;2-3","article-title":"The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide","volume":"43","author":"Schellekens","year":"2000","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0070","doi-asserted-by":"crossref","first-page":"R1421","DOI":"10.1186\/ar1845","article-title":"Identification of citrullinated alpha-enolase as a candidate autoantigen in rheumatoid arthritis","volume":"7","author":"Kinloch","year":"2005","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0075","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1136\/ard.2008.091355","article-title":"Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles","volume":"68","author":"Snir","year":"2009","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0080","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1136\/ard.2004.029389","article-title":"Antibodies to citrullinated human fibrinogen (ACF) have diagnostic and prognostic value in early arthritis","volume":"64","author":"Nielen","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0085","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1080\/03009740802220067","article-title":"Antibodies against mutated citrullinated vimentin fail to predict anti-TNFalpha treatment response in rheumatoid arthritis","volume":"38","author":"Dejaco","year":"2009","journal-title":"Scand J Rheumatol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0090","first-page":"1002","article-title":"Antibodies against mutated citrullinated vimentin are a better predictor of disease activity at 24 months in early rheumatoid arthritis than antibodies against cyclic citrullinated peptides","volume":"35","author":"Innala","year":"2008","journal-title":"J Rheumatol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0095","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.autrev.2009.04.006","article-title":"Anti-citrullinated protein\/peptide autoantibodies in association with genetic and environmental factors as indicators of disease outcome in rheumatoid arthritis","volume":"9","author":"Szodoray","year":"2010","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0100","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1097\/01.bor.0000160780.13012.be","article-title":"Understanding the genetic contribution to rheumatoid arthritis","volume":"17","author":"van der Helm-van Mil","year":"2005","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0105","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/ncprheum0249","article-title":"Mechanisms of disease: Genetic susceptibility and environmental triggers in the development of rheumatoid arthritis","volume":"2","author":"Klareskog","year":"2006","journal-title":"Nat Clin Pract Rheumatol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0110","doi-asserted-by":"crossref","first-page":"R142","DOI":"10.1186\/ar1149","article-title":"Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin","volume":"6","author":"Vossenaar","year":"2004","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0115","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1373\/clinchem.2006.078063","article-title":"Technical and diagnostic performance of 6 assays for the measurement of citrullinated protein\/peptide antibodies in the diagnosis of rheumatoid arthritis","volume":"53","author":"Coenen","year":"2007","journal-title":"Clin Chem"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0120","doi-asserted-by":"crossref","first-page":"R119","DOI":"10.1186\/ar2008","article-title":"Diagnostic value of antibodies against a modified citrullinated vimentin in rheumatoid arthritis","volume":"8","author":"Dejaco","year":"2006","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0125","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/art.23188","article-title":"Antibodies against citrullinated vimentin in rheumatoid arthritis: higher sensitivity and extended prognostic value concerning future radiographic progression as compared with antibodies against cyclic citrullinated peptides","volume":"58","author":"Mathsson","year":"2008","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0130","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s12016-007-8016-3","article-title":"Antibodies to citrullinated vimentin are a specific and sensitive marker for the diagnosis of rheumatoid arthritis","volume":"34","author":"Poulsom","year":"2008","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0135","doi-asserted-by":"crossref","first-page":"27189","DOI":"10.1074\/jbc.M802818200","article-title":"Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes","volume":"283","author":"Beltrami","year":"2008","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0140","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1136\/ard.2009.108456","article-title":"The diagnostic value of anti-MCV antibodies in differentiating early inflammatory arthritis","volume":"69","author":"Damjanovska","year":"2010","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0145","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1136\/ard.2005.038828","article-title":"Antibodies against human 60kDa heat shock protein are not associated with cardiovascular disease in patients with rheumatoid arthritis","volume":"65","author":"van Halm","year":"2006","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0150","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/S0049-0172(96)80043-6","article-title":"Anti-heat-shock protein antibodies in rheumatic and autoimmune diseases","volume":"26","author":"Tishler","year":"1996","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0155","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1111\/j.1365-3083.1989.tb02459.x","article-title":"Elevated IgG antibody levels to the mycobacterial 65-kDa heat shock protein are characteristic of patients with rheumatoid arthritis","volume":"30","author":"Tsoulfa","year":"1989","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0160","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1097\/00002281-199108000-00015","article-title":"Infection as a cause of arthritis","volume":"3","author":"Moreland","year":"1991","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0165","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0008-8749(91)90182-B","article-title":"T cell activation by mycobacterial antigens in inflammatory synovitis","volume":"133","author":"Pope","year":"1991","journal-title":"Cell Immunol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0170","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1093\/rheumatology\/29.6.426","article-title":"Specific antibody response to the mycobacterial 65kDa stress protein in ankylosing spondylitis and rheumatoid arthritis","volume":"29","author":"McLean","year":"1990","journal-title":"Br J Rheumatol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0175","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/art.1780270401","article-title":"Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria","volume":"27","author":"van der Linden","year":"1984","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0180","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1002\/art.22597","article-title":"Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark","volume":"56","author":"Pedersen","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0185","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1046\/j.1365-2362.2001.00819.x","article-title":"Comparative study on antibodies to human and bacterial 60kDa heat shock proteins in a large cohort of patients with coronary heart disease and healthy subjects","volume":"31","author":"Prohaszka","year":"2001","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0190","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1146\/annurev.immunol.26.021607.090244","article-title":"Immunity to citrullinated proteins in rheumatoid arthritis","volume":"26","author":"Klareskog","year":"2008","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.jbspin.2011.03.010_bib0195","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1093\/rheumatology\/ken077","article-title":"Synovial detection and autoantibody reactivity of processed citrullinated isoforms of vimentin in inflammatory arthritides","volume":"47","author":"Tilleman","year":"2008","journal-title":"Rheumatology (Oxford)"}],"container-title":["Joint Bone Spine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1297319X11000686?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1297319X11000686?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,2]],"date-time":"2018-12-02T01:54:26Z","timestamp":1543715666000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1297319X11000686"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["S1297319X11000686"],"URL":"https:\/\/doi.org\/10.1016\/j.jbspin.2011.03.010","relation":{},"ISSN":["1297-319X"],"issn-type":[{"value":"1297-319X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}