{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T08:38:47Z","timestamp":1765960727301},"reference-count":37,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Joint Bone Spine"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.jbspin.2012.09.005","type":"journal-article","created":{"date-parts":[[2012,11,16]],"date-time":"2012-11-16T13:04:59Z","timestamp":1353071099000},"page":"539-543","source":"Crossref","is-referenced-by-count":21,"title":["Update on gout 2012"],"prefix":"10.1016","volume":"79","author":[{"given":"Alexander","family":"So","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Busso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbspin.2012.09.005_bib0005","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1002\/art.22767","article-title":"Quality of care for gout in the US needs improvement","volume":"57","author":"Singh","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0010","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1136\/ard.2009.123687","article-title":"Limited validity of the American College of Rheumatology criteria for classifying patients with gout in primary care","volume":"69","author":"Janssens","year":"2010","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0015","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1001\/archinternmed.2010.196","article-title":"A diagnostic rule for acute gouty arthritis in primary care without joint fluid analysis","volume":"170","author":"Janssens","year":"2010","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0020","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1136\/ard.2008.099713","article-title":"Dual energy computed tomography in tophaceous gout","volume":"68","author":"Choi","year":"2009","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0025","doi-asserted-by":"crossref","DOI":"10.1136\/annrheumdis-2011-200976","article-title":"Dual energy CT in gout: a prospective validation study","author":"Choi","year":"2012","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbspin.2012.01.012","article-title":"Usefulness of ultrasonography for gout","author":"Ottaviani","year":"2012","journal-title":"Joint Bone Spine"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0035","first-page":"499","article-title":"Ultrasonography in gout: a case-control study","volume":"30","author":"Ottaviani","year":"2012","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0040","first-page":"816","article-title":"An exploratory ultrasound study of early gout","volume":"29","author":"Ottaviani","year":"2011","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0045","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1136\/ard.2011.154997","article-title":"Diagnosis of gout in patients with asymptomatic hyperuricaemia: a pilot ultrasound study","volume":"71","author":"De Miguel","year":"2012","journal-title":"Annals Rheum Dis"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0050","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1002\/acr.20527","article-title":"Reproducibility of musculoskeletal ultrasound for determining monosodium urate deposition: concordance between readers","volume":"63","author":"Howard","year":"2011","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0055","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.amjmed.2011.11.010","article-title":"Nature versus nurture in gout: a twin study","volume":"125","author":"Krishnan","year":"2012","journal-title":"Am J Med"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0060","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1038\/ng.972","article-title":"Identification of low-frequency variants associated with gout and serum uric acid levels","volume":"9","author":"Sulem","year":"2011","journal-title":"Nat Genet"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0065","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1172\/JCI42344","article-title":"Uric acid transport and disease","volume":"120","author":"So","year":"2010","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0070","first-page":"105","article-title":"Studies of the hypertension-hyperglycemia-hyperuricemia syndrome","volume":"44","author":"Kylin","year":"1923","journal-title":"Zentralbl Inn Med"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0075","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/acr.20065","article-title":"Hyperuricemia and coronary heart disease: a systematic review and meta-analysis","volume":"62","author":"Kim","year":"2010","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0080","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/acr.20344","article-title":"Hyperuricemia and incident hypertension: a systematic review and meta-analysis","volume":"63","author":"Grayson","year":"2011","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0085","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1161\/CIRCULATIONAHA.107.703389","article-title":"Independent impact of gout on mortality and risk for coronary heart disease","volume":"116","author":"Choi","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0090","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1136\/ard.2009.122770","article-title":"Independent impact of gout on the risk of acute myocardial infarction among elderly women: a population-based study","volume":"69","author":"De Vera","year":"2010","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0095","doi-asserted-by":"crossref","first-page":"e19901","DOI":"10.1371\/journal.pone.0019901","article-title":"Elevated serum uric acid is associated with high circulating inflammatory cytokines in the population-based colaus study","volume":"6","author":"Lyngdoh","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0100","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/j.0105-2896.2009.00860.x","article-title":"Mechanisms of uric acid crystal-mediated autoinflammation","volume":"233","author":"Martinon","year":"2010","journal-title":"Immunol Rev"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0105","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1038\/nature11290","article-title":"Novel role of PKR in inflammasome activation and HMGB1 release","volume":"30","author":"Lu","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0110","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1126\/science.1217141","article-title":"GBP5 promotes NLRP3-inflammasome assembly and immunity in mammals","volume":"336","author":"Shenoy","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0115","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1189\/jlb.0307174","article-title":"Crystal-induced neutrophil activation. IX. Syk-dependent activation of class Ia phosphatidylinositol 3-kinase","volume":"82","author":"Popa-Nita","year":"2007","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0120","doi-asserted-by":"crossref","first-page":"3651","DOI":"10.1002\/art.25006","article-title":"Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta","volume":"60","author":"Joosten","year":"2009","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0125","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1002\/art.30147","article-title":"Octacalcium phosphate crystals induce inflammation in vivo through interleukin-1 but independent of the NLRP3-inflammasome in mice","volume":"63","author":"Narayan","year":"2011","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0130","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1002\/art.20317","article-title":"Macrophage release of transforming growth factor beta1 during resolution of monosodium urate monohydrate crystal-induced inflammation","volume":"50","author":"Yagnik","year":"2004","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0135","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1136\/annrheumdis-2011-201215","article-title":"Purine-rich foods intake and recurrent gout attacks","volume":"71","author":"Zhang","year":"2012","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0140","doi-asserted-by":"crossref","first-page":"3237","DOI":"10.1002\/art.27667","article-title":"Engagement of fatty acids with toll-like receptor 2 drives interleukin-1beta production via the ASC\/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis","volume":"62","author":"Joosten","year":"2010","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0145","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1136\/annrheumdis-2012-eular.1782","article-title":"Toll-like receptor 4 agonists MRP 8 and MRP 14 act as endogenous enhancers of MSU-crystal-induced IL-1 secretion in vitro and reflect disease activity in gout patients in vivo","volume":"71","author":"Holzinger","year":"2012","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0150","doi-asserted-by":"crossref","DOI":"10.1136\/annrheumdis-2011-200908","article-title":"Canakinumab for acute gouty arthritis in patients with limited treatment options: results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions","author":"Schlesinger","year":"2012","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0155","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1136\/ard.2010.144063","article-title":"Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study","volume":"70","author":"Schlesinger","year":"2011","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0160","article-title":"Rilonacept (Interleukin-1 Trap) for prevention of gout flares during initiation of uric acid-lowering therapy: results of the presurge-1 trial","author":"Schumacher","year":"2012","journal-title":"Arthritis Care Res"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0165","first-page":"152","article-title":"Evaluation of rilonacept for prevention of gout flares during initiation of urate-lowering therapy: results of a phase 3, randomized, double-blind, placebo-controlled trial","volume":"62","author":"Terkeltaub","year":"2010","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0170","first-page":"163","article-title":"The safety and efficacy of anakinra in the treatment of acute gout in hospitalized patients","volume":"62","author":"Cho","year":"2010","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0175","doi-asserted-by":"crossref","first-page":"R28","DOI":"10.1186\/ar2143","article-title":"A pilot study of IL-1 inhibition by anakinra in acute gout","volume":"9","author":"So","year":"2007","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0180","doi-asserted-by":"crossref","first-page":"R63","DOI":"10.1186\/ar2978","article-title":"The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial","volume":"12","author":"Becker","year":"2010","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.jbspin.2012.09.005_bib0185","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1001\/jama.2011.1169","article-title":"Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials","volume":"306","author":"Sundy","year":"2011","journal-title":"JAMA"}],"container-title":["Joint Bone Spine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1297319X12002102?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1297319X12002102?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T12:16:38Z","timestamp":1714565798000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1297319X12002102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S1297319X12002102"],"URL":"https:\/\/doi.org\/10.1016\/j.jbspin.2012.09.005","relation":{},"ISSN":["1297-319X"],"issn-type":[{"value":"1297-319X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}