{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:32:42Z","timestamp":1786991562170,"version":"build-2736575974"},"reference-count":62,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Joint Bone Spine"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.jbspin.2012.09.008","type":"journal-article","created":{"date-parts":[[2013,1,14]],"date-time":"2013-01-14T13:54:28Z","timestamp":1358171668000},"page":"11-17","source":"Crossref","is-referenced-by-count":46,"title":["Optimizing combination rifampin therapy for staphylococcal osteoarticular infections"],"prefix":"10.1016","volume":"80","author":[{"given":"Guillaume","family":"Coiffier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-David","family":"Albert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9dric","family":"Arvieux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Guggenbuhl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbspin.2012.09.008_bib0005","doi-asserted-by":"crossref","unstructured":"Recommandations de pratique clinique. Infections ost\u00e9o-articulaires sur mat\u00e9riel (proth\u00e8se, implant, ost\u00e9osynth\u00e8se). Med Mal Infect 2009;39:745\u201374.","DOI":"10.1016\/j.medmal.2009.05.003"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0010","doi-asserted-by":"crossref","unstructured":"Spondylodiscites infectieuses primitives, et secondaires \u00e0 un geste intra-discal, sans mise en place de mat\u00e9riel. Texte court. Med Mal Infect 2007;37:554\u201372.","DOI":"10.1016\/j.medmal.2007.03.008"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0015","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/S0140-6736(09)61595-6","article-title":"Bacterial septic arthritis in adults","volume":"375","author":"Mathews","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0020","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1128\/CMR.00034-09","article-title":"Rifampin combination therapy for nonmycobacterial infections","volume":"23","author":"Forrest","year":"2010","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0025","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/S0092-8674(01)00286-0","article-title":"Structural mechanism for rifampicin inhibition of bacterial RNA polymerase","volume":"104","author":"Campbell","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0030","unstructured":"Monographie de \u00ab\u00a0RIFADINE 300MG GEL\u00a0\u00bb. Pharmacocin\u00e9tique. Vidal 2011. Avaible from: URL: http:\/\/www.vidal.fr\/Medicament\/rifadine-14476.htm."},{"key":"10.1016\/j.jbspin.2012.09.008_bib0035","first-page":"2265","article-title":"Diffusion in bone tissue of antibiotics","volume":"28","author":"Boselli","year":"1999","journal-title":"Presse Med"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0040","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1126\/science.284.5418.1318","article-title":"Bacterial biofilms: a common cause of persistent infections","volume":"284","author":"Costerton","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0045","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1128\/AAC.34.10.1865","article-title":"Influence of growth rate on susceptibility to antimicrobial agents: biofilms, cell cycle, dormancy, and stringent response","volume":"34","author":"Gilbert","year":"1990","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0050","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1002\/jor.20003","article-title":"Intracellular Staphylococcus aureus and antibiotic resistance: implications for treatment of staphylococcal osteomyelitis","volume":"24","author":"Ellington","year":"2006","journal-title":"J Orthop Res"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0055","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1038\/ja.2007.72","article-title":"In vitro activity of novel rifamycins against gram-positive clinical isolates","volume":"60","author":"Murphy","year":"2007","journal-title":"J Antibiot (Tokyo)"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0060","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1128\/AAC.50.1.55-61.2006","article-title":"Multiple combination bactericidal testing of staphylococcal biofilms from implant-associated infections","volume":"50","author":"Sanginur","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0065","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1093\/jac\/dkq094","article-title":"Occurrence and molecular caracterization of fusidic acid resistance mechanisms among Staphylococcus spp. Fron European countries (2008)","volume":"65","author":"Castanheira","year":"2010","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0070","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S1473-3099(01)00094-9","article-title":"Systematic review and meta-analysis of antibiotic therapy for bone and joint infections","volume":"1","author":"Stengel","year":"2001","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0075","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1093\/cid\/cir402","article-title":"Outcome and predictors of treatment failure in total hip\/knee prosthetic joint infections due to Staphylococcus aureus","volume":"53","author":"Senneville","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0080","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1001\/jama.279.19.1537","article-title":"Role of rifampin for treatment of orthopedic implant-related staphylococcal infections: a randomized controlled trial. Foreign-Body Infection (FBI) Study Group","volume":"279","author":"Zimmerli","year":"1998","journal-title":"JAMA"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0085","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ijantimicag.2008.03.003","article-title":"Levofloxacin plus rifampicin conservative treatment of 25 early staphylococcal infections of osteosynthetic devices for rigid internal fixation","volume":"32","author":"Barberan","year":"2008","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0090","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1111\/j.1469-0691.2005.01230.x","article-title":"Use of rifampicin and ciprofloxacin combination therapy after surgical debridement in the treatment of early manifestation prosthetic joint infections","volume":"11","author":"Berdal","year":"2005","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0095","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1128\/AAC.37.6.1214","article-title":"Oral rifampin plus ofloxacin for treatment of Staphylococcus-infected orthopedic implants","volume":"37","author":"Drancourt","year":"1993","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0100","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1093\/jac\/48.6.927","article-title":"Rifampicin-ofloxacin oral regimen for the treatment of mild to moderate diabetic foot osteomyelitis","volume":"48","author":"Senneville","year":"2001","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0105","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1001\/archinte.168.8.805","article-title":"Adjunctive use of rifampin for the treatment of Staphylococcus aureus Infections. A systematic review of the literature","volume":"168","author":"Perlroth","year":"2008","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0110","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1086\/521894","article-title":"Rifampicin reduces plasma concentrations of moxifloxacin in patients with tuberculosis","volume":"45","author":"Nijland","year":"2007","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0115","doi-asserted-by":"crossref","first-page":"S509","DOI":"10.1093\/clinids\/5.Supplement_3.S509","article-title":"In vitro study of the combination of rifampin with oxacillin against Staphylococcus aureus","volume":"5","author":"Van der Auwera","year":"1983","journal-title":"Rev Infect Dis"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0120","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1128\/AAC.38.9.2191","article-title":"Failure of time-kill synergy studies using subinhibitory antimicrobial concentrations to predict in vivo antagonism of cephalosporin\u2013rifampin combinations against Staphylococcus aureus","volume":"38","author":"Brandt","year":"1994","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0125","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/infdis\/144.4.365","article-title":"Antistaphylococcal activity of rifampin with other antibiotics","volume":"144","author":"Zinner","year":"1981","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0130","doi-asserted-by":"crossref","first-page":"S491","DOI":"10.1093\/clinids\/5.Supplement_3.S491","article-title":"Experimental chronic staphylococcal osteomyelitis in rabbits: treatment with rifampin alone and in combination with other antimicrobial agents","volume":"5","author":"Norden","year":"1983","journal-title":"Rev Infect Dis"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0135","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1093\/jac\/19.3.313","article-title":"Comparative in vitro activities of teicoplanin, vancomycin, coumermycin and ciprofloxacin, alone and in combination with rifampicin or LM 427, against Staphylococcus aureus","volume":"19","author":"Van der Auwera","year":"1987","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0140","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1128\/AAC.23.6.932","article-title":"Synergy of combinations of vancomycin, gentamicin, and rifampin against methicillin-resistant, coagulase-negative staphylococci","volume":"23","author":"Lowy","year":"1983","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0145","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1128\/AAC.26.2.220","article-title":"Disparity between timed-kill and checkerboard methods for determination of in vitro bactericidal interactions of vancomycin plus rifampin versus methicillin-susceptible and -resistant Staphylococcus aureus","volume":"26","author":"Bayer","year":"1984","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0150","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1093\/jac\/dkn513","article-title":"Impact of biofilm on the in vitro activity of vancomycin alone and in combination with tigecycline and rifampicin against Staphylococcus aureus","volume":"63","author":"Rose","year":"2009","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0155","doi-asserted-by":"crossref","first-page":"S543","DOI":"10.1093\/clinids\/5.Supplement_3.S543","article-title":"Rifampin treatment of prosthetic valve endocarditis due to Staphylococcus epidermidis","volume":"5","author":"Karchmer","year":"1983","journal-title":"Rev Infect Dis"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0160","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1128\/AAC.00300-08","article-title":"Addition of rifampin to standard therapy for treatment of native valve Staphylococcus aureus infective endocarditis","volume":"52","author":"Riedel","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0165","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.jinf.2006.11.011","article-title":"Oral step-down therapy is comparable to intravenous therapy for Staphylococcus aureus osteomyelitis","volume":"54","author":"Daver","year":"2007","journal-title":"J Infect"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0170","doi-asserted-by":"crossref","first-page":"S130","DOI":"10.1016\/S0399-077X(04)90127-8","article-title":"Faut-il diff\u00e9rer l\u2019introduction de la rifampicine lors d\u2019une bact\u00e9ri\u00e9mie prolong\u00e9e \u00e0 Staphylococcus aureus\u00a0?","volume":"34","author":"Schaller","year":"2004","journal-title":"Med Mal Infect"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0175","doi-asserted-by":"crossref","first-page":"674","DOI":"10.7326\/0003-4819-115-9-674","article-title":"Slow response to vancomycin or vancomycin plus rifampin in methicillin-resistant Staphylococcus aureus endocarditis","volume":"115","author":"Levine","year":"1991","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0180","doi-asserted-by":"crossref","first-page":"S477","DOI":"10.1093\/cid\/cir163","article-title":"In vitro antimicrobial findings for fusidic acid tested against contemporary (2008\u20132009) Gram-positive organisms collected in the United States","volume":"52","author":"Jones","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0185","doi-asserted-by":"crossref","first-page":"S493","DOI":"10.1093\/cid\/cir165","article-title":"Activity of fusidic acid against extracellular and intracellular Staphylococcus aureus: influence of pH and comparaison with linezolid and clindamycin","volume":"52","author":"Lemaire","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0190","unstructured":"Monographie de \u00ab\u00a0FUCIDINE 250MG CP PELLIC\u00a0\u00bb. Pharmacocin\u00e9tique. Vidal 2011. Avaible from: URL: http:\/\/www.vidal.fr\/Medicament\/fucidine-7199.htm."},{"key":"10.1016\/j.jbspin.2012.09.008_bib0195","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1128\/AAC.30.1.174","article-title":"Interaction between rifampin and fusidic acid against methicillin-resistant coagulase-positive and -negative staphylococci","volume":"30","author":"Farber","year":"1986","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0200","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1093\/jac\/11.1.21","article-title":"In vitro effects of vancomycin, rifampicin, and fusidic acid, alone and in combination, against methicillin-resistant Staphylococcus aureus","volume":"11","author":"Foldes","year":"1983","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0205","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1111\/j.1469-0691.2007.01691.x","article-title":"Treatment of staphylococcal prosthetic joint infections with debridement, prosthesis retention and oral rifampicin and fusidic acid","volume":"13","author":"Aboltins","year":"2007","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0210","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/jac\/39.2.235","article-title":"Oral treatment of Staphylococcus sp infected orthopaedic implants with fusidic acid or ofloxacin in combination with rifampicin","volume":"39","author":"Drancourt","year":"1997","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0215","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0732-8893(86)90147-1","article-title":"In vitro evaluation of clindamycin in combination with oxacillin, rifampin, or vancomycin against Staphylococcus aureus","volume":"4","author":"Ho","year":"1986","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0220","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/jac\/16.3.335","article-title":"Effects of clindamycin in combination with rifampicin on clindamycin-susceptible and clindamycin-resistant Staphylococcus aureus","volume":"16","author":"Watanakunakorn","year":"1985","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0225","unstructured":"Monographie de \u00ab\u00a0DALACINE 600mg sol inj\u00a0\u00bb. Pharmacocin\u00e9tique. Vidal 2011. Available at http:\/\/www.vidal.fr\/Medicament\/dalacine-4770.htm."},{"key":"10.1016\/j.jbspin.2012.09.008_bib0230","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.medmal.2008.06.030","article-title":"Treatment of osteoarticular infections with clindamycin in adults","volume":"38","author":"El Samad","year":"2008","journal-title":"Med Mal Infect"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0235","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1128\/AAC.01081-09","article-title":"Continuous clindamycin infusion, an innovative approach to treating bone and joint infections","volume":"54","author":"Zeller","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0240","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1016\/S0399-077X(09)74434-8","article-title":"Comparaison des associations rifampicine\u2013clindamycine et rifampicine\u2013ofloxacine dans le traitement des infections ost\u00e9o-articulaires staphylococciques sur mat\u00e9riel orthop\u00e9dique","volume":"39","author":"De Coppet","year":"2009","journal-title":"Med Mal Infect"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0245","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1093\/jac\/4.4.315","article-title":"Antagonistic interaction of rifampicin and trimethoprim","volume":"4","author":"Harvey","year":"1978","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0250","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1128\/AAC.29.4.611","article-title":"Serum bactericidal activity of rifampin in combination with other antimicrobial agents against Staphylococcus aureus","volume":"9","author":"Hackbarth","year":"1986","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0255","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s10156-007-0521-Z","article-title":"The bactericidal effects of anti-MRSA agents with rifampicin and sulfamethoxazole-trimethoprim against intracellular phagocytised MRSA","volume":"13","author":"Yamaoka","year":"2007","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0260","unstructured":"Monograph for \u201cBACTRIM FORTE cp\u201d. Pharmacocin\u00e9tique. Vidal 2011. Avaible from: URL: http:\/\/www.vidal.fr\/Medicament\/bactrim_forte-1850.htm."},{"key":"10.1016\/j.jbspin.2012.09.008_bib0265","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1128\/AAC.17.4.591","article-title":"Treatment of experimental staphylococcal osteomyelitis with rifampin and trimethoprim, alone and in combination","volume":"17","author":"Norden","year":"1980","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0270","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1128\/AAC.01504-08","article-title":"Long-term follow-up trial of oral rifampin\u2013cotrimoxazole combination versus intravenous cloxacillin in treatment of chronic staphylococcal osteomyelitis","volume":"53","author":"Euba","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0275","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1093\/jac\/dkp346","article-title":"Effects of daptomycin in combination with other antimicrobial agents: a review of in vitro and animal model studies","volume":"64","author":"Steenbergen","year":"2009","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0280","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s00284-011-9980-7","article-title":"In vitro activity of daptomycin, linezolid and rifampicin on Staphylococcus epidermidis biofilms","volume":"63","author":"Leite","year":"2011","journal-title":"Curr Microbiol"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0285","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1345\/aph.1K535","article-title":"Clinical experience with daptomycin for the treatment of patients with documented gram-positive septic arthritis","volume":"42","author":"Forrest","year":"2008","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0290","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1016\/j.spinee.2008.11.008","article-title":"Daptomycin for methicillin-resistant Staphylococcus aureus infections of the spine","volume":"9","author":"Burdette","year":"2009","journal-title":"Spine J"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0295","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1093\/jac\/dkq281","article-title":"Tolerability of prolonged linezolid therapy in bone and joint infection: protective effect of rifampicin on the occurrence of anaemia?","volume":"65","author":"Legout","year":"2010","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0300","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1111\/j.1469-0691.2009.02761.x","article-title":"Efficacy and tolerance of rifampicin\u2013linezolid compared with rifampicin\u2013cotrimoxazole combinations in prolonged oral therapy for bone and joint infections","volume":"15","author":"Nguyen","year":"2009","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0305","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1093\/jac\/dkh191","article-title":"Antibiotic treatment of gram-positive bone and joint infections","volume":"53","author":"Darley","year":"2004","journal-title":"Antimicrob Chemother"},{"key":"10.1016\/j.jbspin.2012.09.008_bib0310","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1086\/429628","article-title":"Use of long-acting tetracyclines for methicillin-resistant Staphylococcus aureus infections: case series and review of the literature","volume":"40","author":"Ruhe","year":"2005","journal-title":"Clin Infect Dis"}],"container-title":["Joint Bone Spine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1297319X12002138?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1297319X12002138?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,19]],"date-time":"2018-10-19T10:21:33Z","timestamp":1539944493000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1297319X12002138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":62,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S1297319X12002138"],"URL":"https:\/\/doi.org\/10.1016\/j.jbspin.2012.09.008","relation":{},"ISSN":["1297-319X"],"issn-type":[{"value":"1297-319X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}