{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T04:37:26Z","timestamp":1759207046653,"version":"3.40.5"},"reference-count":36,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Joint Bone Spine"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.jbspin.2015.09.007","type":"journal-article","created":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T10:37:59Z","timestamp":1458383879000},"page":"517-523","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["In arthritis the Doppler based degree of hypervascularisation shows a positive correlation with synovial leukocyte count and distinguishes joints with leukocytes greater and less than 5\/nL"],"prefix":"10.1016","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9401-3811","authenticated-orcid":false,"given":"Christian","family":"L\u00f6ffler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Horst","family":"Sattler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Peters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anika","family":"Tuleweit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uta","family":"L\u00f6ffler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Wadsack","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Uppenkamp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7965-1273","authenticated-orcid":false,"given":"Raoul","family":"Bergner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jbspin.2015.09.007_bib0185","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1053\/euje.3.3.240","article-title":"The difference between colour doppler velocity imaging and power Doppler imaging","volume":"3","author":"McDicken","year":"2002","journal-title":"Eur Hear J Cardiovasc Imaging"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0190","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1093\/rheumatology\/ket405","article-title":"Ultrasonographic examination of rheumatoid arthritis patients who are free of physical synovitis: power Doppler subclinical synovitis is associated with bone erosion","volume":"53","author":"Kawashiri","year":"2014","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0195","doi-asserted-by":"crossref","first-page":"93","DOI":"10.6061\/clinics\/2014(02)04","article-title":"Is painless synovitis different from painful synovitis? A controlled, ultrasound, radiographic, clinical trial","volume":"69","author":"Pereira","year":"2014","journal-title":"Clinics (Sao Paulo)"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0200","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1002\/art.21015","article-title":"Linking angiogenesis to bone destruction in arthritis","volume":"52","author":"Pap","year":"2005","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0205","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1136\/ard.54.6.511","article-title":"Synovial membrane cellularity and vascularity","volume":"54","author":"FitzGerald","year":"1995","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0210","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1002\/1529-0131(199806)41:6<951::AID-ART2>3.0.CO;2-D","article-title":"Review: angiogenesis: implications for rheumatoid arthritis","volume":"41","author":"Koch","year":"1998","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0215","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1002\/1529-0131(200102)44:2<331::AID-ANR50>3.0.CO;2-0","article-title":"Correlation of power Doppler sonography with vascularity of the synovial tissue of the knee joint in patients with osteoarthritis and rheumatoid arthritis","volume":"44","author":"Walther","year":"2001","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0220","first-page":"480","article-title":"[Correlation of power Doppler sonography with vascularity of the synovial tissue]","volume":"39","author":"Labanauskaite","year":"2003","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0225","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1136\/annrheumdis-2012-202669","article-title":"Ultrasound colour Doppler is associated with synovial pathology in biopsies from hand joints in rheumatoid arthritis patients: a cross-sectional study","volume":"73","author":"Andersen","year":"2014","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0230","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1093\/rheumatology\/keu154","article-title":"Structural deterioration of finger joints with ultrasonographic synovitis in rheumatoid arthritis patients with clinical low disease activity","volume":"53","author":"Fukae","year":"2014","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0235","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.jbspin.2013.08.006","article-title":"Ultrasound evaluation of synovitis in RA: correlation with clinical disease activity and sensitivity to change in an observational cohort study","volume":"81","author":"Zufferey","year":"2014","journal-title":"Joint Bone Spine"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0240","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1093\/rheumatology\/ket311","article-title":"Sonographic synovial vascularity of synovitis in rheumatoid arthritis","volume":"53","author":"Fukae","year":"2014","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0245","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ejim.2013.08.700","article-title":"Ultrasonography in the diagnosis and management of patients with inflammatory arthritides","volume":"25","author":"Epis","year":"2014","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0250","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/art.22461","article-title":"Longitudinal power Doppler ultrasonographic assessment of joint inflammatory activity in early rheumatoid arthritis: predictive value in disease activity and radiologic progression","volume":"57","author":"Naredo","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0255","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0950-3579(96)80047-1","article-title":"Synovial fluid cell analysis","volume":"10","author":"Dougados","year":"1996","journal-title":"Baillieres Clin Rheumatol"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0260","first-page":"145","article-title":"The importance of urgent cytological examination of synovial fluids in differentiation inflammatory and non-inflammatory joint diseases","volume":"34","author":"Ostovi\u013f","year":"2010","journal-title":"Coll Antropol"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0265","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/0002-9343(79)90790-3","article-title":"Synovial fluid leukocytosis. A study of extremes","volume":"67","author":"Krey","year":"1979","journal-title":"Am J Med"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0270","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3109\/03009749209099243","article-title":"Synovial fluid leukocytosis in bacterial arthritis vs. reactive arthritis and rheumatoid arthritis in the adult knee","volume":"21","author":"Kortekangas","year":"1992","journal-title":"Scand J Rheumatol"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0275","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0012516","article-title":"Linking power Doppler ultrasound to the presence of th17 cells in the rheumatoid arthritis joint","volume":"5","author":"Gullick","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0280","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1002\/art.38376","article-title":"Interleukin-17+CD8+T cells are enriched in the joints of patients with psoriatic arthritis and correlate with disease activity and joint damage progression","volume":"66","author":"Menon","year":"2014","journal-title":"Arthritis Rheumatol (Hoboken, NJ)"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0285","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1093\/rheumatology\/kep171","article-title":"Ultrasonographic evaluation of joint involvement in early rheumatoid arthritis in clinical remission: power Doppler signal predicts short-term relapse","volume":"48","author":"Scir\u00e8","year":"2009","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0290","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/rheumatology\/kep442","article-title":"Superiority of SDAI over DAS-28 in assessment of remission in rheumatoid arthritis patients using power Doppler ultrasonography as a gold standard","volume":"49","author":"Balsa","year":"2010","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0295","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1002\/art.10877","article-title":"Interobserver agreement in ultrasonography of the finger and toe joints in rheumatoid arthritis","volume":"48","author":"Szkudlarek","year":"2003","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0300","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1002\/art.27584","article-title":"2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology\/European League against Rheumatism collaborative initiative","volume":"62","author":"Aletaha","year":"2010","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0305","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1136\/ard.2010.133645","article-title":"The Assessment of SpondyloArthritis International Society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general","volume":"70","author":"Rudwaleit","year":"2011","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0310","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1111\/os.12024","article-title":"Current concepts in the treatment of gouty arthritis","volume":"5","author":"Fang","year":"2013","journal-title":"Orthop Surg"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0315","first-page":"2","article-title":"Ultrasound imaging for the rheumatologist. XXV. Sonographic assessment of the knee in patients with gout and calcium pyrophosphate deposition disease","volume":"28","author":"Filippucci","year":"2010","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0320","first-page":"830","article-title":"Value of a short four-joint ultrasound test for gout diagnosis: a pilot study","volume":"30","author":"Peiteado","year":"2012","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0325","doi-asserted-by":"crossref","first-page":"513","DOI":"10.3899\/jrheum.140634","article-title":"In acute arthritis the sonographic double contour sign in combination with hypervascularisation and serum uric acid levels can distinguish gout arthritis from calcium pyrophosphate disease and other arthritides","volume":"42","author":"L\u00f6ffler","year":"2015","journal-title":"J Rheumatol"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0330","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/RHU.0b013e31827d8790","article-title":"Mechanistic aspects of inflammation and clinical management of inflammation in acute gouty arthritis","volume":"19","author":"Cronstein","year":"2014","journal-title":"J Clin Rheumatol"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0335","doi-asserted-by":"crossref","first-page":"4","DOI":"10.12703\/P6-4","article-title":"Advances in treating psoriasis","volume":"6","author":"Belge","year":"2014","journal-title":"F1000Prime Rep"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0340","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.clim.2012.12.011","article-title":"Immunopathogenesis of osteoarthritis","volume":"146","author":"Haseeb","year":"2013","journal-title":"Clin Immunol"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0345","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/BF02030245","article-title":"Bacterial arthritis: are fever, rigors, leucocytosis and blood cultures of diagnostic value?","volume":"9","author":"Schlapbach","year":"1990","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0350","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1097\/00003086-199008000-00037","article-title":"Synovial leukocytosis in infectious arthritis","volume":"257","author":"McCutchan","year":"1990","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0355","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1007\/s00296-012-2452-y","article-title":"Relationship of ultrasonographic findings with synovial angiogenesis modulators in different forms of knee arthritides","volume":"33","author":"Gok","year":"2013","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.jbspin.2015.09.007_bib0360","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1093\/rheumatology\/keh380","article-title":"A new approach to studying angiogenesis in rheumatoid arthritis by means of power Doppler ultrasonography and measurement of serum vascular endothelial growth factor","volume":"43","author":"Strunk","year":"2004","journal-title":"Rheumatology (Oxford)"}],"container-title":["Joint Bone Spine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1297319X16000117?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1297319X16000117?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T17:57:06Z","timestamp":1655315826000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1297319X16000117"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["S1297319X16000117"],"URL":"https:\/\/doi.org\/10.1016\/j.jbspin.2015.09.007","relation":{},"ISSN":["1297-319X"],"issn-type":[{"type":"print","value":"1297-319X"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In arthritis the Doppler based degree of hypervascularisation shows a positive correlation with synovial leukocyte count and distinguishes joints with leukocytes greater and less than 5\/nL","name":"articletitle","label":"Article Title"},{"value":"Joint Bone Spine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jbspin.2015.09.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Soci\u00e9t\u00e9 fran\u00e7aise de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}