{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:34:37Z","timestamp":1790836477114,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","award":["945698"],"award-info":[{"award-number":["945698"]}],"id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofcardiovascularct.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiovascular Computed Tomography"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.jcct.2021.11.014","type":"journal-article","created":{"date-parts":[[2021,11,27]],"date-time":"2021-11-27T02:28:16Z","timestamp":1637980096000},"page":"254-261","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Patient-specific computer simulation to predict long-term outcomes after transcatheter aortic valve replacement"],"prefix":"10.1016","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3191-5361","authenticated-orcid":false,"given":"Cameron","family":"Dowling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Gooley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liam","family":"McCormick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami","family":"Firoozi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Brecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcct.2021.11.014_bib1","article-title":"Transcatheter aortic valve replacement versus surgery for symptomatic severe aortic stenosis: a reconstructed individual patient data meta-analysis","author":"Dowling","year":"2019","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2021.11.014_bib2","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1056\/NEJMoa1814052","article-title":"Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients","volume":"380","author":"Mack","year":"2019","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcct.2021.11.014_bib3","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1056\/NEJMoa1816885","article-title":"Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients","volume":"380","author":"Popma","year":"2019","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcct.2021.11.014_bib4","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1001\/jamacardio.2017.3425","article-title":"Association of paravalvular regurgitation with 1-year outcomes after transcatheter aortic valve replacement with the SAPIEN 3 valve","volume":"2","author":"Pibarot","year":"2017","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jcct.2021.11.014_bib5","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.119.009178","article-title":"Patient-specific computer simulation of transcatheter aortic valve replacement in bicuspid aortic valve morphology","volume":"12","author":"Dowling","year":"2019","journal-title":"Circ Cardiovasc Imag"},{"key":"10.1016\/j.jcct.2021.11.014_bib29","doi-asserted-by":"crossref","DOI":"10.1080\/24748706.2021.1991604","article-title":"Patient-specific computer simulation to optimize transcatheter heart valve sizing and positioning in bicuspid aortic valve","author":"Dowling","year":"2021","journal-title":"Struct Heart"},{"key":"10.1016\/j.jcct.2021.11.014_bib6","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.jcin.2016.01.003","article-title":"Patient-specific computer modeling to predict aortic regurgitation after transcatheter aortic valve replacement","volume":"9","author":"de Jaegere","year":"2016","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2021.11.014_bib7","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.jcin.2019.07.032","article-title":"First-in-Human experience with patient-specific computer simulation of TAVR in bicuspid aortic valve morphology","volume":"13","author":"Dowling","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2021.11.014_bib8","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1016\/j.jcin.2020.04.018","article-title":"Patient-specific computer simulation in TAVR with the self-expanding Evolut R valve","volume":"13","author":"El Faquir","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2021.11.014_bib9","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/j.jtcvs.2007.01.039","article-title":"A\u00a0classification system for the bicuspid aortic valve from 304 surgical specimens","volume":"133","author":"Sievers","year":"2007","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jcct.2021.11.014_bib10","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.jcin.2012.09.007","article-title":"Aortic root dimensions among patients with severe aortic stenosis undergoing transcatheter aortic valve replacement","volume":"6","author":"Buellesfeld","year":"2013","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2021.11.014_bib11","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1093\/ehjci\/jeu162","article-title":"A\u00a0revised methodology for aortic-valvar complex calcium quantification for transcatheter aortic valve implantation","volume":"15","author":"Jilaihawi","year":"2014","journal-title":"Eur Heart J Cardiovasc Imag"},{"key":"10.1016\/j.jcct.2021.11.014_bib12","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.115.003282","article-title":"Relationship of annular sizing using multidetector computed tomographic imaging and clinical outcomes after self-expanding corevalve transcatheter aortic valve replacement","volume":"9","author":"Popma","year":"2016","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2021.11.014_bib13","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.4244\/EIJV11I9A212","article-title":"Patient-specific image-based computer simulation for theprediction of valve morphology and calcium displacement after TAVI with the Medtronic CoreValve and the Edwards SAPIEN valve","volume":"11","author":"Schultz","year":"2016","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcct.2021.11.014_bib14","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.117.005344","article-title":"Patient-specific computer simulation to elucidate the role of contact pressure in the development of New conduction abnormalities after catheter-based implantation of a self-expanding aortic valve","volume":"11","author":"Rocatello","year":"2018","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2021.11.014_bib30","article-title":"Patient-specific computer simulation: an emerging technology for Guiding the transcatheter treatment of patients with bicuspid aortic valve","volume":"16","author":"Dowling","year":"2021","journal-title":"Intervent Cardiol"},{"key":"10.1016\/j.jcct.2021.11.014_bib15","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1093\/eurheartj\/ehu162","article-title":"Treatment of aortic stenosis with a self-expanding transcatheter valve: the International Multi-centre ADVANCE Study","volume":"35","author":"Linke","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcct.2021.11.014_bib16","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.jcin.2016.11.025","article-title":"Initial experience of a second-generation self-expanding transcatheter aortic valve: the UK & Ireland Evolut R implanters' registry","volume":"10","author":"Kalra","year":"2017","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2021.11.014_bib17","first-page":"751","article-title":"Initial experience of a large, self-expanding, and fully recapturable transcatheter aortic valve: the UK & Ireland Implanters' registry","volume":"93","author":"Dowling","year":"2019","journal-title":"Cathet Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2021.11.014_bib18","first-page":"1340","article-title":"Initial experience of a self-expanding transcatheter aortic valve with an outer pericardial wrap: the United Kingdom and Ireland Implanters' registry","volume":"95","author":"Dowling","year":"2020","journal-title":"Cathet Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2021.11.014_bib19","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.jcmg.2015.01.008","article-title":"Assessment of paravalvular regurgitation following TAVR: a proposal of unifying grading scheme","volume":"8","author":"Pibarot","year":"2015","journal-title":"JACC Cardiovasc Imag"},{"key":"10.1016\/j.jcct.2021.11.014_bib20","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.jacc.2009.04.075","article-title":"Geometry and degree of apposition of the CoreValve ReValving system with multislice computed tomography after implantation in patients with aortic stenosis","volume":"54","author":"Schultz","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcct.2021.11.014_bib21","doi-asserted-by":"crossref","first-page":"s44","DOI":"10.1136\/heartjnl-2018-313518","article-title":"Transcatheter versus surgical intervention: lessons from trials of coronary revascularisation","volume":"105","author":"Gunn","year":"2019","journal-title":"Heart"},{"key":"10.1016\/j.jcct.2021.11.014_bib22","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1056\/NEJMoa1910555","article-title":"Five-year outcomes of transcatheter or surgical aortic-valve replacement","volume":"382","author":"Makkar","year":"2020","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcct.2021.11.014_bib23","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jcin.2019.08.035","article-title":"Three generations of self-expanding transcatheter aortic valves: a report from the STS\/ACC TVT registry","volume":"13","author":"Forrest","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2021.11.014_bib24","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1136\/heartjnl-2014-305665","article-title":"Aortic regurgitation severity after transcatheter aortic valve implantation is underestimated by echocardiography compared with MRI","volume":"100","author":"Orwat","year":"2014","journal-title":"Heart"},{"key":"10.1016\/j.jcct.2021.11.014_bib25","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1136\/heartjnl-2014-305615","article-title":"Cardiac magnetic resonance versus transthoracic echocardiography for the assessment and quantification of aortic regurgitation in patients undergoing transcatheter aortic valve implantation","volume":"100","author":"Ribeiro","year":"2014","journal-title":"Heart"},{"key":"10.1016\/j.jcct.2021.11.014_bib26","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.jacc.2016.05.059","article-title":"Cardiovascular magnetic resonance to evaluate aortic regurgitation after transcatheter aortic valve replacement","volume":"68","author":"Ribeiro","year":"2016","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcct.2021.11.014_bib27","doi-asserted-by":"crossref","first-page":"355","DOI":"10.4244\/EIJY14M05_06","article-title":"An objective and reproducible method for quantification of aortic regurgitation after TAVI","volume":"10","author":"Schultz","year":"2014","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcct.2021.11.014_bib28","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.4244\/EIJV11I12A271","article-title":"Video densitometric assessment of aortic regurgitation after transcatheter aortic valve implantation: results from the Brazilian TAVI registry","volume":"11","author":"Tateishi","year":"2016","journal-title":"EuroIntervention"}],"container-title":["Journal of Cardiovascular Computed Tomography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934592521004743?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934592521004743?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T14:03:39Z","timestamp":1761833019000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1934592521004743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["S1934592521004743"],"URL":"https:\/\/doi.org\/10.1016\/j.jcct.2021.11.014","relation":{},"ISSN":["1934-5925"],"issn-type":[{"value":"1934-5925","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Patient-specific computer simulation to predict long-term outcomes after transcatheter aortic valve replacement","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiovascular Computed Tomography","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcct.2021.11.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}