{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T12:40:41Z","timestamp":1789389641233,"version":"build-2803163510"},"reference-count":29,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["journalofcardiovascularct.com","clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiovascular Computed Tomography"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.jcct.2023.08.008","type":"journal-article","created":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T13:59:23Z","timestamp":1693490363000},"page":"384-392","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Pericoronary adipose tissue attenuation is associated with non-calcified plaque burden in patients with chronic coronary syndromes"],"prefix":"10.1016","volume":"17","author":[{"given":"Alexander","family":"Giesen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Mouselimis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8353-2769","authenticated-orcid":false,"given":"Loris","family":"Weichsel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0938-3170","authenticated-orcid":false,"given":"Andreas A.","family":"Giannopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Schmermund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Nunninger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moritz","family":"Schuetz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1428-2611","authenticated-orcid":false,"given":"Florian","family":"Andr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Frey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6038-2253","authenticated-orcid":false,"given":"Grigorios","family":"Korosoglou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jcct.2023.08.008_bib1","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"Knuuti","year":"2020","journal-title":"Eur Heart J"},{"issue":"11","key":"10.1016\/j.jcct.2023.08.008_bib2","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1161\/ATVBAHA.119.312899","article-title":"Cardiac computed tomography: assessment of coronary inflammation and other plaque features","volume":"39","author":"Oikonomou","year":"2019","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"10151","key":"10.1016\/j.jcct.2023.08.008_bib3","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/S0140-6736(18)31114-0","article-title":"Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis of prospective outcome data","volume":"392","author":"Oikonomou","year":"2018","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.jcct.2023.08.008_bib4","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1007\/s00259-020-05106-0","article-title":"Quantification of perivascular inflammation does not provide incremental prognostic value over myocardial perfusion imaging and calcium scoring","volume":"48","author":"Bengs","year":"2021","journal-title":"Eur J Nucl Med Mol Imag"},{"issue":"12","key":"10.1016\/j.jcct.2023.08.008_bib5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0052081","article-title":"HMGB1 is associated with atherosclerotic plaque composition and burden in patients with stable coronary artery disease","volume":"7","author":"Andrassy","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.jcct.2023.08.008_bib6","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1148\/radiol.15141110","article-title":"Combined assessment of high-sensitivity troponin T and noninvasive coronary plaque composition for the prediction of cardiac outcomes","volume":"276","author":"Gitsioudis","year":"2015","journal-title":"Radiology"},{"issue":"10","key":"10.1016\/j.jcct.2023.08.008_bib7","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1136\/hrt.2010.193201","article-title":"Determinants of troponin release in patients with stable coronary artery disease: insights from CT angiography characteristics of atherosclerotic plaque","volume":"97","author":"Korosoglou","year":"2011","journal-title":"Heart"},{"issue":"1","key":"10.1016\/j.jcct.2023.08.008_bib8","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.jcmg.2020.09.004","article-title":"SCCT guideline for training Cardiology and radiology trainees as independent practitioners (level II) and advanced practitioners (level III) in cardiovascular computed tomography: a statement from the society of cardiovascular computed tomography","volume":"14","author":"Choi","year":"2020","journal-title":"JACC Cardiovasc Imaging"},{"issue":"11","key":"10.1016\/j.jcct.2023.08.008_bib9","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.jacr.2022.09.012","volume":"19","author":"Cury","year":"2022","journal-title":"J\u00a0Am Coll Radiol"},{"key":"10.1016\/j.jcct.2023.08.008_bib10","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.atherosclerosis.2022.10.006","article-title":"Association of epicardial adipose tissue with coronary CT angiography plaque parameters on cardiovascular outcome\u00a0in\u00a0patients\u00a0with and without diabetes mellitus","volume":"363","author":"Tesche","year":"2022","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jcct.2023.08.008_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.896321","article-title":"Commentary: plaque features and epicardial fat volume for cardiovascular risk assessment-A key role with cardiac computed tomography?","volume":"9","author":"Tesche","year":"2022","journal-title":"Front Cardiovasc Med"},{"issue":"12","key":"10.1016\/j.jcct.2023.08.008_bib12","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.jcmg.2012.03.019","article-title":"The napkin-ring sign indicates advanced atherosclerotic lesions in coronary CT angiography","volume":"5","author":"Maurovich-Horvat","year":"2012","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.jcct.2023.08.008_bib13","article-title":"The influence of effective energy on computed tomography number depends on tissue characteristics in monoenergetic cardiac imaging","volume":"2012","author":"Okayama","year":"2012","journal-title":"Radiol Res Pract"},{"issue":"398","key":"10.1016\/j.jcct.2023.08.008_bib14","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aal2658","article-title":"Detecting human coronary\u00a0inflammation by imaging perivascular fat","volume":"9","author":"Antonopoulos","year":"2017","journal-title":"Sci Transl Med"},{"issue":"12","key":"10.1016\/j.jcct.2023.08.008_bib15","doi-asserted-by":"crossref","first-page":"6838","DOI":"10.1007\/s00330-020-07069-0","article-title":"Towards reference values of pericoronary adipose tissue attenuation: impact of coronary artery and tube voltage in coronary computed tomography angiography","volume":"30","author":"Ma","year":"2020","journal-title":"Eur Radiol"},{"issue":"3","key":"10.1016\/j.jcct.2023.08.008_bib16","doi-asserted-by":"crossref","first-page":"203","DOI":"10.11613\/BM.2011.029","article-title":"Multiple comparison analysis testing in ANOVA","volume":"21","author":"McHugh","year":"2011","journal-title":"Biochem Med"},{"key":"10.1016\/j.jcct.2023.08.008_bib17","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.atherosclerosis.2020.12.001","article-title":"Coronary computed tomography angiography in asymptomatic patients: still a taboo or precision medicine?","volume":"317","author":"Korosoglou","year":"2021","journal-title":"Atherosclerosis"},{"issue":"23","key":"10.1016\/j.jcct.2023.08.008_bib18","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1016\/j.jacc.2009.09.009","article-title":"Inflammation in atherosclerosis: from pathophysiology to practice","volume":"54","author":"Libby","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"21","key":"10.1016\/j.jcct.2023.08.008_bib19","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1016\/j.jacc.2007.02.052","article-title":"C-reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus","volume":"49","author":"Ridker","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.jcct.2023.08.008_bib20","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/s41392-021-00658-5","article-title":"Inflammation and tumor progression: signaling\u00a0pathways\u00a0and targeted intervention","volume":"6","author":"Zhao","year":"2021","journal-title":"Signal Transduct Targeted Ther"},{"issue":"5","key":"10.1016\/j.jcct.2023.08.008_bib21","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.jcct.2019.03.006","article-title":"State-of-the-art review article. Atherosclerosis affecting fat: what can we learn by imaging perivascular adipose tissue?","volume":"13","author":"Antoniades","year":"2019","journal-title":"J\u00a0Cardiovasc Comput Tomogr"},{"issue":"398","key":"10.1016\/j.jcct.2023.08.008_bib22","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aal2658","article-title":"Detecting human coronary inflammation by imaging perivascular fat","volume":"9","author":"Antonopoulos","year":"2017","journal-title":"Sci Transl Med"},{"issue":"12","key":"10.1016\/j.jcct.2023.08.008_bib23","doi-asserted-by":"crossref","first-page":"e526","DOI":"10.1093\/ehjci\/jeac174","article-title":"Pericoronary fat attenuation index-a new imaging biomarker and its diagnostic and prognostic utility: a systematic\u00a0review\u00a0and meta-analysis","volume":"23","author":"Sagris","year":"2022","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"6","key":"10.1016\/j.jcct.2023.08.008_bib24","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.jcmg.2022.02.004","article-title":"Pericoronary adipose tissue attenuation, low-attenuation plaque burden, and 5-year risk of myocardial infarction","volume":"15","author":"Tzolos","year":"2022","journal-title":"JACC Cardiovasc Imaging"},{"issue":"2","key":"10.1016\/j.jcct.2023.08.008_bib25","article-title":"Pericoronary fat attenuation index is associated with vulnerable plaque components and local immune-inflammatory activation in patients with non-ST elevation acute coronary syndrome","volume":"11","author":"Sun","year":"2022","journal-title":"J\u00a0Am Heart Assoc"},{"issue":"8","key":"10.1016\/j.jcct.2023.08.008_bib26","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1016\/j.jcmg.2021.02.026","article-title":"Prognostic value of RCA pericoronary adipose tissue CT-attenuation beyond high-risk plaques, plaque volume, and ischemia","volume":"14","author":"van Diemen","year":"2021","journal-title":"JACC Cardiovasc Imaging"},{"issue":"6","key":"10.1016\/j.jcct.2023.08.008_bib27","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.jacc.2020.05.078","article-title":"Perivascular fat attenuation index stratifies cardiac risk associated with high-risk plaques in the CRISP-CT study","volume":"76","author":"Oikonomou","year":"2020","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"4","key":"10.1016\/j.jcct.2023.08.008_bib28","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1253\/circj.CJ-21-0698","volume":"86","author":"Koga","year":"2022","journal-title":"Circ J"},{"issue":"25","key":"10.1016\/j.jcct.2023.08.008_bib29","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1016\/j.jacc.2007.02.059","article-title":"Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior","volume":"49","author":"Chatzizisis","year":"2007","journal-title":"J\u00a0Am Coll Cardiol"}],"container-title":["Journal of Cardiovascular Computed Tomography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193459252300415X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193459252300415X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T14:40:05Z","timestamp":1716648005000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S193459252300415X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S193459252300415X"],"URL":"https:\/\/doi.org\/10.1016\/j.jcct.2023.08.008","relation":{},"ISSN":["1934-5925"],"issn-type":[{"value":"1934-5925","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pericoronary adipose tissue attenuation is associated with non-calcified plaque burden in patients with chronic coronary syndromes","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiovascular Computed Tomography","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcct.2023.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}