{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T04:03:27Z","timestamp":1792641807244,"version":"4.5.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["journalofcardiovascularct.com","clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiovascular Computed Tomography"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.jcct.2024.04.009","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T12:42:04Z","timestamp":1714135324000},"page":"401-407","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Coronary plaque phenotype associated with positive remodeling"],"prefix":"10.1016","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5571-5079","authenticated-orcid":false,"given":"Daisuke","family":"Kinoshita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5543-2420","authenticated-orcid":false,"given":"Keishi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2284-7611","authenticated-orcid":false,"given":"Haruhito","family":"Yuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1586-4971","authenticated-orcid":false,"given":"Takayuki","family":"Niida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daichi","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyasu","family":"Minami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damini","family":"Dey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris","family":"McNulty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6645-6404","authenticated-orcid":false,"given":"Junya","family":"Ako","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maros","family":"Ferencik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4004-5292","authenticated-orcid":false,"given":"Tsunekazu","family":"Kakuta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Chul","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5796-3006","authenticated-orcid":false,"given":"Ik-Kyung","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcct.2024.04.009_bib1","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1161\/CIRCULATIONAHA.116.021314","article-title":"Distribution of estimated 10-year risk of recurrent vascular events and residual risk in a secondary prevention population","volume":"134","author":"Kaasenbrood","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.jcct.2024.04.009_bib2","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1001\/jamacardio.2017.4973","article-title":"Use of high-risk coronary atherosclerotic plaque detection for risk stratification of patients with stable chest pain: a secondary analysis of the PROMISE randomized clinical trial","volume":"3","author":"Ferencik","year":"2018","journal-title":"JAMA cardiology"},{"key":"10.1016\/j.jcct.2024.04.009_bib3","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.jacr.2022.09.012","article-title":"An expert consensus document of the society of cardiovascular computed tomography (SCCT), the American College of Cardiology (ACC), the American College of Radiology (ACR) and the North America society of cardiovascular imaging (NASCI)","volume":"19","author":"Cury","year":"2022","journal-title":"J\u00a0Am Coll Radiol"},{"key":"10.1016\/j.jcct.2024.04.009_bib4","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1016\/j.jcmg.2021.03.019","article-title":"Risk stratification with the use of coronary computed tomographic angiography in patients with nonobstructive coronary artery disease","volume":"14","author":"Taron","year":"2021","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcct.2024.04.009_bib5","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/ehjci\/jeu188","article-title":"Atherosclerotic plaque characterization by CT angiography for identification of high-risk coronary artery lesions: a comparison to optical coherence tomography","volume":"16","author":"Nakazato","year":"2015","journal-title":"Eur Heart J Cardiovas Imag"},{"key":"10.1016\/j.jcct.2024.04.009_bib6","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1016\/j.amjcard.2010.12.036","article-title":"Comparison of in vivo assessment of vulnerable plaque by 64-slice multislice computed tomography versus optical coherence tomography","volume":"107","author":"Ito","year":"2011","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcct.2024.04.009_bib7","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jacc.2018.10.066","article-title":"Coronary artery plaque characteristics associated with adverse outcomes in the SCOT-HEART study","volume":"73","author":"Williams","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcct.2024.04.009_bib8","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1056\/NEJM198705283162204","article-title":"Compensatory enlargement of human atherosclerotic coronary arteries","volume":"316","author":"Glagov","year":"1987","journal-title":"N\u00a0Engl J Med"},{"issue":"10","key":"10.1016\/j.jcct.2024.04.009_bib9","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/s41569-022-00687-9","article-title":"Optical coherence tomography in coronary atherosclerosis assessment and intervention","volume":"19","author":"Araki","year":"2022","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jcct.2024.04.009_bib10","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jacc.2020.11.030","article-title":"Machine learning and the future of cardiovascular care: JACC state-of-the-art review","volume":"77","author":"Quer","year":"2021","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcct.2024.04.009_bib11","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1056\/NEJMp1705348","article-title":"Lost in thought - the limits of the human mind and the future of medicine","volume":"377","author":"Obermeyer","year":"2017","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jcct.2024.04.009_bib12","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1126\/science.1957169","article-title":"Optical coherence tomography","volume":"254","author":"Huang","year":"1991","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.jcct.2024.04.009_bib13","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/s41569-022-00687-9","article-title":"Optical coherence tomography in coronary atherosclerosis assessment and intervention","volume":"19","author":"Araki","year":"2022","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jcct.2024.04.009_bib14","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.jcct.2016.10.006","article-title":"Erratum to \"Abstracts of the 11th annual scientific meeting of the society of cardiovascular computed tomography\" [J Cardiovasc Comput Tomogr 10 (3) (2016) S1-S96]","volume":"10","year":"2016","journal-title":"J\u00a0Cardiovas Comp Tomograp"},{"issue":"4","key":"10.1016\/j.jcct.2024.04.009_bib15","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.jcmg.2023.08.005","article-title":"High-risk plaques on coronary computed tomography angiography: correlation with optical coherence tomography","volume":"17","author":"Kinoshita","year":"2024","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcct.2024.04.009_bib16","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1016\/j.jcmg.2022.04.016","article-title":"Association between changes in perivascular adipose tissue density and plaque progression","volume":"15","author":"Lee","year":"2022","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcct.2024.04.009_bib17","article-title":"All models are wrong, but many are useful: learning a variable's importance by studying an entire class of prediction models simultaneously","volume":"20","author":"Fisher","year":"2019","journal-title":"J\u00a0Mach Learn Res"},{"key":"10.1016\/j.jcct.2024.04.009_bib18","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1093\/ehjci\/jead009","article-title":"A\u00a0streamlined, machine learning-derived approach to risk-stratification in heart failure patients with secondary tricuspid regurgitation","volume":"24","author":"Heitzinger","year":"2023","journal-title":"Eur Heart J Cardiovas Imag"},{"key":"10.1016\/j.jcct.2024.04.009_bib19","article-title":"DALEX: explainers for complex predictive models in R","volume":"19","author":"Biecek","year":"2018","journal-title":"J\u00a0Mach Learn Res"},{"key":"10.1016\/j.jcct.2024.04.009_bib20","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1161\/CIRCULATIONAHA.117.029289","article-title":"Standardized end point definitions for coronary intervention trials: the academic research consortium-2 consensus document","volume":"137","author":"Garcia-Garcia","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.jcct.2024.04.009_bib21","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1161\/hc0802.104327","article-title":"Relationship between coronary artery remodeling and plaque vulnerability","volume":"105","author":"Varnava","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jcct.2024.04.009_bib22","doi-asserted-by":"crossref","first-page":"747","DOI":"10.4070\/kcj.2012.42.11.747","article-title":"Positive vascular remodeling in culprit coronary lesion is associated with plaque composition: an intravascular ultrasound-virtual histology study","volume":"42","author":"Lee","year":"2012","journal-title":"Kor Circ J"},{"key":"10.1016\/j.jcct.2024.04.009_bib23","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/0735-1097(94)90632-7","article-title":"Determinants of coronary compliance in patients with coronary artery disease: an intravascular ultrasound study","volume":"23","author":"Alfonso","year":"1994","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcct.2024.04.009_bib24","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1093\/eurheartj\/ehad161","article-title":"Proteomics and lipidomics in atherosclerotic cardiovascular disease risk prediction","volume":"44","author":"Nurmohamed","year":"2023","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcct.2024.04.009_bib25","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1161\/res.90.3.251","article-title":"Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly","volume":"90","author":"Galis","year":"2002","journal-title":"Circ Res"},{"key":"10.1016\/j.jcct.2024.04.009_bib26","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.jcmg.2017.03.005","article-title":"Coronary artery calcification: from mechanism to molecular imaging","volume":"10","author":"Nakahara","year":"2017","journal-title":"J\u00a0Am Coll Cardiol Img"},{"key":"10.1016\/j.jcct.2024.04.009_bib27","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1161\/01.CIR.95.7.1791","article-title":"Contribution of inadequate arterial remodeling to the development of focal coronary artery stenoses. An intravascular ultrasound study","volume":"95","author":"Mintz","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.jcct.2024.04.009_bib28","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1016\/S0002-9149(97)00682-6","article-title":"Predictors of coronary arterial remodeling patterns in patients with myocardial ischemia","volume":"80","author":"Tauth","year":"1997","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcct.2024.04.009_bib29","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0002-9149(99)00222-2","article-title":"Remodeling of atherosclerotic coronary arteries varies in relation to location and composition of plaque","volume":"84","author":"Sabat\u00e9","year":"1999","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jcct.2024.04.009_bib30","doi-asserted-by":"crossref","first-page":"2826","DOI":"10.1161\/CIRCULATIONAHA.105.585703","article-title":"Determinants of arterial wall remodeling during lipid-lowering therapy: serial intravascular ultrasound observations from the Reversal of Atherosclerosis with Aggressive Lipid Lowering Therapy (REVERSAL) trial","volume":"113","author":"Schoenhagen","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.jcct.2024.04.009_bib31","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1016\/j.jacc.2016.08.040","article-title":"Statin medication enhances progression of coronary artery calcification: the heinz nixdorf recall study","volume":"68","author":"Dykun","year":"2016","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcct.2024.04.009_bib32","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1161\/ATVBAHA.122.318177","article-title":"Regulated necrosis in atherosclerosis","volume":"42","author":"Puylaert","year":"2022","journal-title":"Arterioscler Thromb Vasc Biol"}],"container-title":["Journal of Cardiovascular Computed Tomography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193459252400100X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193459252400100X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T07:16:17Z","timestamp":1719818177000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S193459252400100X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S193459252400100X"],"URL":"https:\/\/doi.org\/10.1016\/j.jcct.2024.04.009","relation":{},"ISSN":["1934-5925"],"issn-type":[{"value":"1934-5925","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coronary plaque phenotype associated with positive remodeling","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiovascular Computed Tomography","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcct.2024.04.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}