{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T08:24:54Z","timestamp":1793521494799,"version":"4.5.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["FS\/14\/78\/31020"],"award-info":[{"award-number":["FS\/14\/78\/31020"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","award":["RE\/18\/5\/34216"],"award-info":[{"award-number":["RE\/18\/5\/34216"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001516","name":"Heart Foundation of New Zealand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001516","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["WT103782AIA"],"award-info":[{"award-number":["WT103782AIA"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000850","name":"National Heart and Lung Institute","doi-asserted-by":"publisher","award":["1R01HL151266"],"award-info":[{"award-number":["1R01HL151266"]}],"id":[{"id":"10.13039\/501100000850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000850","name":"National Heart and Lung Institute","doi-asserted-by":"publisher","award":["1R01HL148787-01A1"],"award-info":[{"award-number":["1R01HL148787-01A1"]}],"id":[{"id":"10.13039\/501100000850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005984","name":"Dr. Miriam and Sheldon G. Adelson Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005984","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000848","name":"University of Edinburgh","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000848","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014589","name":"Chief Scientist Office, Scottish Government Health and Social Care Directorate","doi-asserted-by":"publisher","award":["PCL\/17\/04"],"award-info":[{"award-number":["PCL\/17\/04"]}],"id":[{"id":"10.13039\/100014589","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014589","name":"Chief Scientist Office, Scottish Government Health and Social Care Directorate","doi-asserted-by":"publisher","award":["CZH\/4\/588"],"award-info":[{"award-number":["CZH\/4\/588"]}],"id":[{"id":"10.13039\/100014589","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000282","name":"Sir Jules Thorn Charitable Trust","doi-asserted-by":"publisher","award":["15\/JTA"],"award-info":[{"award-number":["15\/JTA"]}],"id":[{"id":"10.13039\/501100000282","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000092","name":"U.S. National Library of Medicine","doi-asserted-by":"publisher","award":["RG\/20\/10\/34966"],"award-info":[{"award-number":["RG\/20\/10\/34966"]}],"id":[{"id":"10.13039\/100000092","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000092","name":"U.S. National Library of Medicine","doi-asserted-by":"publisher","award":["CH\/F\/21\/90010"],"award-info":[{"award-number":["CH\/F\/21\/90010"]}],"id":[{"id":"10.13039\/100000092","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000092","name":"U.S. National Library of Medicine","doi-asserted-by":"publisher","award":["FS\/14\/78\/31020"],"award-info":[{"award-number":["FS\/14\/78\/31020"]}],"id":[{"id":"10.13039\/100000092","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010898","name":"Edinburgh and Lothians Health Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010898","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofcardiovascularct.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiovascular Computed Tomography"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.jcct.2024.12.083","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T00:35:35Z","timestamp":1736382935000},"page":"208-214","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Impact of diabetes mellitus on coronary artery plaque characteristics and outcomes in the SCOT-HEART trial"],"prefix":"10.1016","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6169-5799","authenticated-orcid":false,"given":"Zuzanna M.","family":"Gebert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Kwiecinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5842-842X","authenticated-orcid":false,"given":"Jonathan R.","family":"Weir-McCall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip D.","family":"Adamson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas L.","family":"Mills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giles","family":"Roditi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2777-5071","authenticated-orcid":false,"given":"Edwin J.R.","family":"van Beek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward D.","family":"Nicol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3793-9578","authenticated-orcid":false,"given":"Daniel S.","family":"Berman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr J.","family":"Slomka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc R.","family":"Dweck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damini","family":"Dey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David E.","family":"Newby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3556-2428","authenticated-orcid":false,"given":"Michelle C.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcct.2024.12.083_bib1","year":"2003","journal-title":"Diabetes"},{"issue":"2","key":"10.1016\/j.jcct.2024.12.083_bib2","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.diabres.2013.11.001","article-title":"Global estimates\u00a0of\u00a0undiagnosed\u00a0diabetes in adults","volume":"103","author":"Beagley","year":"2014","journal-title":"Diabetes Res Clin Pract"},{"issue":"4","key":"10.1016\/j.jcct.2024.12.083_bib3","article-title":"Ho Y.L.,et\u00a0al. Diabetes mellitus-related all-cause and cardiovascular mortality in a national cohort of adults","volume":"8","author":"Raghavan","year":"2019","journal-title":"J\u00a0Am Heart Assoc"},{"issue":"6","key":"10.1016\/j.jcct.2024.12.083_bib4","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/S0735-1097(02)02975-3","article-title":"The prevalence of coronary artery calcium among diabetic individuals without known coronary artery disease","volume":"41","author":"Hoff","year":"2003","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"8","key":"10.1016\/j.jcct.2024.12.083_bib5","doi-asserted-by":"crossref","first-page":"108237","DOI":"10.1016\/j.jdiacomp.2022.108237","article-title":"Prevalence, determinants and prognostic value of high coronary artery calcium score in asymptomatic patients with diabetes: a systematic review and meta-analysis","volume":"36","author":"Sow","year":"2022","journal-title":"J\u00a0Diabetes Complicat"},{"issue":"1","key":"10.1016\/j.jcct.2024.12.083_bib6","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1186\/s12933-021-01350-2","article-title":"Andersen T.R.,et\u00a0al. High-risk coronary artery plaque in asymptomatic patients with type 2 diabetes: clinical risk factors and coronary artery calcium score","volume":"20","author":"Heinsen","year":"2021","journal-title":"Cardiovasc Diabetol"},{"issue":"1","key":"10.1016\/j.jcct.2024.12.083_bib7","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/s12933-023-01850-3","article-title":"Harjulahti E.,et\u00a0al. The impact of diabetes on the relationship of coronary artery disease and outcome: a study using multimodality imaging","volume":"22","author":"M\u00e4enp\u00e4\u00e4","year":"2023","journal-title":"Cardiovasc Diabetol"},{"issue":"7","key":"10.1016\/j.jcct.2024.12.083_bib8","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1097\/CM9.0000000000000733","article-title":"Li Z.N.,et\u00a0al. Quantification of atherosclerotic plaque volume in coronary arteries by computed tomographic angiography in subjects with and without diabetes","volume":"133","author":"Hou","year":"2020","journal-title":"Chin Med J"},{"key":"10.1016\/j.jcct.2024.12.083_bib9","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.atherosclerosis.2016.11.004","article-title":"Plaque progression assessed by a novel semi-automated quantitative plaque software on coronary computed tomography angiography between diabetes and non-diabetes patients: a propensity-score matching study","volume":"255","author":"Nakanishi","year":"2016","journal-title":"Atherosclerosis"},{"issue":"10","key":"10.1016\/j.jcct.2024.12.083_bib10","first-page":"1461","article-title":"Sellers S.L.,et\u00a0al. Natural history of diabetic coronary atherosclerosis by quantitative measurement of serial coronary computed tomographic angiography: results of the PARADIGM study","volume":"11","author":"Kim","year":"2018","journal-title":"JACC (J Am Coll Cardiol): Cardiovascular Imaging"},{"issue":"9985","key":"10.1016\/j.jcct.2024.12.083_bib11","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1016\/S0140-6736(15)60291-4","article-title":"SCOT-HEART Investigators. CT coronary angiography in patients with suspected angina due to coronary heart disease (SCOT-HEART): an open-label, parallel-group, multicentre trial","volume":"385","year":"2015","journal-title":"Lancet"},{"issue":"10","key":"10.1016\/j.jcct.2024.12.083_bib12","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1056\/NEJMoa1805971","article-title":"SCOT-HEART Investigators. Coronary CT angiography and 5-year risk of myocardial infarction","volume":"379","year":"2018","journal-title":"N\u00a0Engl J Med"},{"issue":"0","key":"10.1016\/j.jcct.2024.12.083_bib13","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1161\/CIRCULATIONAHA.119.044720","article-title":"Doris M.,et\u00a0al. Low-attenuation noncalcified plaque on coronary computed tomography angiography predicts myocardial infarction. Results From Multicent SCOT-HEART Trial (Scottish Comp Tomograp of the HEART)","volume":"141","author":"Williams","year":"2020","journal-title":"Circ"},{"issue":"2","key":"10.1016\/j.jcct.2024.12.083_bib14","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1136\/hrt.2006.108167","article-title":"Adding social deprivation and family history to cardiovascular risk assessment: the ASSIGN score from the Scottish Heart Health Extended Cohort (SHHEC)","volume":"93","author":"Woodward","year":"2007","journal-title":"Heart"},{"key":"10.1016\/j.jcct.2024.12.083_bib15","series-title":"Chest Pain of Recent Onset: Assessment and Diagnosis","year":"2016"},{"issue":"4","key":"10.1016\/j.jcct.2024.12.083_bib16","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0735-1097(90)90282-T","article-title":"Detrano R.et\u00a0al. Quantification of coronary artery calcium using ultrafast computed tomography","volume":"15","author":"Agatston","year":"1990","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.jcct.2024.12.083_bib17","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jacc.2018.10.066","article-title":"Coronary artery plaque characteristics associated with adverse outcomes in the SCOT-heart study","volume":"73","author":"Williams","year":"2019","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jcct.2024.12.083_bib18","first-page":"f1654","article-title":"Gross J.L.et\u00a0al. Coronary artery calcium score prediction of all cause mortality and cardiovascular events in people with type 2 diabetes: systematic review and meta-analysis","volume":"346","author":"Kramer","year":"2013","journal-title":"BMJ Br Med J (Clin Res Ed)"},{"issue":"12","key":"10.1016\/j.jcct.2024.12.083_bib19","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1001\/jamacardio.2017.4191","article-title":"Budoff M.,et\u00a0al. Coronary artery calcium score for long-term risk classification in individuals with type 2 diabetes and metabolic syndrome from the multi-ethnic study of atherosclerosis","volume":"2","author":"Malik","year":"2017","journal-title":"JAMA Cardiol"},{"issue":"7","key":"10.1016\/j.jcct.2024.12.083_bib20","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1016\/S0735-1097(00)00986-4","article-title":"Fuller J.H.,et\u00a0al. The effect of type 1 diabetes mellitus on the gender difference in coronary artery calcification","volume":"36","author":"Colhoun","year":"2000","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"9","key":"10.1016\/j.jcct.2024.12.083_bib21","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1016\/j.jacc.2003.09.068","article-title":"Callister T.Q.,et\u00a0al. Prognostic value of coronary artery calcium screening in subjects with and without diabetes","volume":"43","author":"Raggi","year":"2004","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.jcct.2024.12.083_bib22","doi-asserted-by":"crossref","first-page":"2196438","DOI":"10.1080\/07853890.2023.2196438","article-title":"Guo H.,et\u00a0al. The impact of baseline calcified plaque volume on coronary rapid plaque progression by serial coronary computed tomography angiography in patients with type 2 diabetes","volume":"55","author":"Jian","year":"2023","journal-title":"Ann Med"},{"issue":"10","key":"10.1016\/j.jcct.2024.12.083_bib23","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1016\/j.jcmg.2018.04.009","article-title":"Sellers S.L.,et\u00a0al. Natural history of diabetic coronary atherosclerosis by quantitative measurement of serial coronary computed tomographic angiography. JACC (J Am Coll Cardiol)","volume":"11","author":"Kim","year":"2018","journal-title":"Cardiovas Imag"},{"issue":"1","key":"10.1016\/j.jcct.2024.12.083_bib24","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/s12933-017-0637-0","article-title":"Mintz G.S.,et\u00a0al. Plaque volume and plaque risk profile in diabetic vs. non-diabetic patients undergoing lipid-lowering therapy: a study based on 3D intravascular ultrasound and virtual histology","volume":"16","author":"Kovarnik","year":"2017","journal-title":"Cardiovasc Diabetol"},{"issue":"7","key":"10.1016\/j.jcct.2024.12.083_bib25","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1161\/01.ATV.0000131783.74034.97","article-title":"Zieske A.,et\u00a0al. Morphologic findings of coronary atherosclerotic plaques in diabetics","volume":"24","author":"Burke","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"4","key":"10.1016\/j.jcct.2024.12.083_bib26","first-page":"378","article-title":"Ninomiya K.,et\u00a0al. Clinical predictors of coronary artery plaque progression by quantitative serial assessment using 320-row computed tomography coronary angiography in asymptomatic patients with type 2 diabetes mellitus","volume":"76","author":"Tanaka","year":"2020","journal-title":"J\u00a0Cardiol"},{"issue":"4","key":"10.1016\/j.jcct.2024.12.083_bib27","article-title":"Ho Y.L.,et\u00a0al. Diabetes mellitus\u2013related all-cause and cardiovascular mortality in a national cohort of adults","volume":"8","author":"Raghavan","year":"2019","journal-title":"J\u00a0Am Heart Assoc"},{"issue":"21","key":"10.1016\/j.jcct.2024.12.083_bib28","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.1001\/jama.2014.15825","article-title":"Effect of screening for coronary artery disease using CT angiography on mortality and cardiac events in high-risk patients with diabetes: the FACTOR-64 randomized clinical trial","volume":"312","author":"Muhlestein","year":"2014","journal-title":"JAMA"},{"issue":"7","key":"10.1016\/j.jcct.2024.12.083_bib29","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.2337\/dc16-0281","article-title":"Takx R.A., et\u00a0al. Prognostic value of coronary computed tomography angiography in patients with diabetes: a meta-analysis","volume":"39","author":"Celeng","year":"2016","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1016\/j.jcct.2024.12.083_bib30","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jcct.2018.09.008","article-title":"Kupke M.,et\u00a0al. Impact of diabetes on coronary artery plaque volume by coronary CT angiography and subsequent adverse cardiac events","volume":"13","author":"Deseive","year":"2019","journal-title":"J\u00a0Cardiovas Comput Tomograp"},{"issue":"7 Pt 2","key":"10.1016\/j.jcct.2024.12.083_bib31","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.jcmg.2018.02.025","article-title":"Barnett-Griness O.,et\u00a0al. Plaque morphology as predictor of late plaque events in patients with asymptomatic type 2 diabetes: a long-term observational study","volume":"12","author":"Halon","year":"2019","journal-title":"JACC Cardiovasc Imaging"}],"container-title":["Journal of Cardiovascular Computed Tomography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934592524005835?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934592524005835?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T08:23:34Z","timestamp":1778833414000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1934592524005835"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S1934592524005835"],"URL":"https:\/\/doi.org\/10.1016\/j.jcct.2024.12.083","relation":{},"ISSN":["1934-5925"],"issn-type":[{"value":"1934-5925","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of diabetes mellitus on coronary artery plaque characteristics and outcomes in the SCOT-HEART trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiovascular Computed Tomography","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcct.2024.12.083","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of Society of Cardiovascular Computed Tomography\u00e9","name":"copyright","label":"Copyright"}]}}