{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T12:07:16Z","timestamp":1789214836218,"version":"build-2803163510"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T00:00:00Z","timestamp":1787356800000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofcardiovascularct.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cardiovascular Computed Tomography"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jcct.2026.07.012","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T06:07:40Z","timestamp":1785996460000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Radiomics-based characterization of valvular calcium improves risk stratification for paravalvular regurgitation after TAVI"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9652-2927","authenticated-orcid":false,"given":"Thamara Carvalho","family":"Morais","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonildes Nascimento","family":"Assun\u00e7\u00e3o J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7057-0322","authenticated-orcid":false,"given":"S\u00e9rgio Figueiredo","family":"C\u00e2mara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2923-4059","authenticated-orcid":false,"given":"Carla Franco","family":"Grego da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Liberato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Morhy","family":"Borges Leal Assun\u00e7\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Kanhouche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4622-7676","authenticated-orcid":false,"given":"Vin\u00edcius Cardoso","family":"Serra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Vaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5000-0955","authenticated-orcid":false,"given":"Marco Antonio","family":"Gelain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Fabio","family":"Sandoli de Brito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8689-9990","authenticated-orcid":false,"given":"Alexandre","family":"Abizaid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique Barbosa","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar Higa","family":"Nomura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcct.2026.07.012_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.shj.2022.100118","article-title":"Impact of paravalvular leak on outcomes after transcatheter aortic valve implantation: meta-analysis of Kaplan-Meier-derived individual patient data","volume":"7","author":"Sa","year":"2023","journal-title":"Struct Heart"},{"key":"10.1016\/j.jcct.2026.07.012_bib2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.4244\/EIJ-D-21-00784","article-title":"Five-year outcomes of mild paravalvular regurgitation after transcatheter aortic valve implantation","volume":"18","author":"Okuno","year":"2022","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcct.2026.07.012_bib3","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1093\/eurheartj\/ehad146","article-title":"Treatment of late paravalvular regurgitation after transcatheter aortic valve implantation: prognostic implications","volume":"44","author":"Landes","year":"2023","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcct.2026.07.012_bib4","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1016\/j.jacc.2020.09.595","article-title":"STS-ACC TVT registry of transcatheter aortic valve replacement","volume":"76","author":"Carroll","year":"2020","journal-title":"JACC (J Am Coll Cardiol)"},{"key":"10.1016\/j.jcct.2026.07.012_bib5","first-page":"895","article-title":"Effect of a fourth-generation transcatheter valve enhanced skirt on paravalvular leak","volume":"97","author":"Welle","year":"2021","journal-title":"Cathet Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2026.07.012_bib6","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.4244\/EIJ-D-20-01293","article-title":"Paravalvular regurgitation after transcatheter aortic valve replacement in intermediate-risk patients: a pooled PARTNER 2 study","volume":"17","author":"Chau","year":"2022","journal-title":"EuroIntervention"},{"key":"10.1016\/j.jcct.2026.07.012_bib7","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1016\/j.jcin.2022.08.057","article-title":"Transcatheter aortic valve replacement with the latest-iteration self-expanding or balloon-expandable valves: the multicenter OPERA-TAVI registry","volume":"15","author":"Costa","year":"2022","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2026.07.012_bib8","doi-asserted-by":"crossref","first-page":"qyae040","DOI":"10.1093\/ehjimp\/qyae040","article-title":"Paravalvular regurgitation after transcatheter aortic valve replacement: incidence, quantification, and prognostic impact","volume":"2","author":"van Wely","year":"2024","journal-title":"Eur Heart J Imaging Methods Pract"},{"key":"10.1016\/j.jcct.2026.07.012_bib9","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/ehjci\/jev174","article-title":"Device landing zone calcification and its impact on residual regurgitation after transcatheter aortic valve implantation with different devices","volume":"17","author":"Seiffert","year":"2016","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jcct.2026.07.012_bib10","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.jcin.2014.03.007","article-title":"Quantity and location of aortic valve complex calcification predicts severity and location of paravalvular regurgitation and frequency of post-dilation after balloon-expandable transcatheter aortic valve replacement","volume":"7","author":"Khalique","year":"2014","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2026.07.012_bib11","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1161\/CIRCULATIONAHA.112.142000","article-title":"Paravalvular aortic leak after transcatheter aortic valve replacement: current knowledge","volume":"127","author":"Lerakis","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.jcct.2026.07.012_bib12","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jcct.2018.02.002","article-title":"Aortic valve and left ventricular outflow tract calcium volume and distribution in transcatheter aortic valve replacement: influence on the risk of significant paravalvular regurgitation","volume":"12","author":"Hansson","year":"2018","journal-title":"J Cardiovasc Comput Tomogr"},{"key":"10.1016\/j.jcct.2026.07.012_bib13","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ijcard.2017.12.052","article-title":"Quantified degree of eccentricity of aortic valve calcification predicts risk of paravalvular regurgitation and response to balloon post-dilation after self-expandable transcatheter aortic valve replacement","volume":"259","author":"Park","year":"2018","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jcct.2026.07.012_bib14","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/j.jcin.2020.04.015","article-title":"Impact of left ventricular outflow tract calcification on procedural outcomes after transcatheter aortic valve replacement","volume":"13","author":"Okuno","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jcct.2026.07.012_bib15","first-page":"190","article-title":"Relationship of aortic annular eccentricity and paravalvular regurgitation post transcatheter aortic valve implantation with CoreValve","volume":"25","author":"Wong","year":"2013","journal-title":"J Invasive Cardiol"},{"key":"10.1016\/j.jcct.2026.07.012_bib16","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1253\/circj.CJ-16-1240","article-title":"Transcatheter aortic valve replacement with different valve types in elliptic aortic annuli","volume":"81","author":"Maeno","year":"2017","journal-title":"Circ J"},{"key":"10.1016\/j.jcct.2026.07.012_bib17","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/j.jacc.2011.11.045","article-title":"Cross-sectional computed tomographic assessment improves accuracy of aortic annular sizing for transcatheter aortic valve replacement and reduces the incidence of paravalvular aortic regurgitation","volume":"59","author":"Jilaihawi","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jcct.2026.07.012_bib18","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s41747-018-0068-z","article-title":"Radiomics: the facts and the challenges of image analysis","volume":"2","author":"Rizzo","year":"2018","journal-title":"Europ Radiol Exp"},{"key":"10.1016\/j.jcct.2026.07.012_bib19","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/jmri.23971","article-title":"Texture analysis in assessment and prediction of chemotherapy response in breast cancer","volume":"38","author":"Ahmed","year":"2013","journal-title":"J Magn Reson Imag"},{"key":"10.1016\/j.jcct.2026.07.012_bib20","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.radonc.2015.02.015","article-title":"CT-based radiomic signature predicts distant metastasis in lung adenocarcinoma","volume":"114","author":"Coroller","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.jcct.2026.07.012_bib21","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.jtho.2016.11.2226","article-title":"Radiomic-based pathological response prediction from primary tumors and lymph nodes in NSCLC","volume":"12","author":"Coroller","year":"2017","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.jcct.2026.07.012_bib22","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1007\/s00330-015-3701-8","article-title":"Haralick texture analysis of prostate MRI: utility for differentiating non-cancerous prostate from prostate cancer and differentiating prostate cancers with different gleason scores","volume":"25","author":"Wibmer","year":"2015","journal-title":"Eur Radiol"},{"key":"10.1016\/j.jcct.2026.07.012_bib23","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.123.015340","article-title":"Development and validation of CCTA-Based radiomics signature for predicting coronary plaques with rapid progression","volume":"16","author":"Chen","year":"2023","journal-title":"Circ, Cardiovasc Imaging"},{"key":"10.1016\/j.jcct.2026.07.012_bib24","doi-asserted-by":"crossref","first-page":"3529","DOI":"10.1093\/eurheartj\/ehz592","article-title":"A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography","volume":"40","author":"Oikonomou","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcct.2026.07.012_bib25","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.120.011747","article-title":"Radiomics: the next frontier of cardiac computed tomography","volume":"14","author":"Xu","year":"2021","journal-title":"Circ, Cardiovasc Imaging"},{"key":"10.1016\/j.jcct.2026.07.012_bib26","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.123.015490","article-title":"Perfect match: radiomics and artificial intelligence in cardiac imaging","volume":"17","author":"Baessler","year":"2024","journal-title":"Circ, Cardiovasc Imaging"},{"key":"10.1016\/j.jcct.2026.07.012_bib27","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1093\/eurheartj\/ehaa799","article-title":"Valve academic research consortium 3: updated endpoint definitions for aortic valve clinical research","volume":"42","author":"Genereux","year":"2021","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jcct.2026.07.012_bib28","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1148\/radiol.2020191145","article-title":"The image biomarker standardization initiative: standardized quantitative radiomics for high-throughput image-based phenotyping","volume":"295","author":"Zwanenburg","year":"2020","journal-title":"Radiology"},{"key":"10.1016\/j.jcct.2026.07.012_bib29","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s13244-023-01415-8","article-title":"CheckList for Evaluation of radiomics research (CLEAR): a step-by-step reporting guideline for authors and reviewers endorsed by ESR and EuSoMII","volume":"14","author":"Kocak","year":"2023","journal-title":"Insights Imaging"},{"key":"10.1016\/j.jcct.2026.07.012_bib30","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1056\/NEJMoa1814052","article-title":"Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients","volume":"380","author":"Mack","year":"2019","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcct.2026.07.012_bib31","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1056\/NEJMoa1816885","article-title":"Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients","volume":"380","author":"Popma","year":"2019","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcct.2026.07.012_bib32","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ijcard.2018.02.042","article-title":"Accuracy of device landing zone calcium volume measurement with contrast-enhanced multidetector computed tomography","volume":"263","author":"Kim","year":"2018","journal-title":"Int J Cardiol"},{"issue":"1","key":"10.1016\/j.jcct.2026.07.012_bib33","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2019-001164","article-title":"Impact of device landing zone calcification patterns on paravalvular regurgitation after transcatheter aortic valve replacement with different next-generation devices","volume":"7","author":"Mauri","year":"2020","journal-title":"Open Heart"},{"key":"10.1016\/j.jcct.2026.07.012_bib34","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1093\/ehjci\/jeu162","article-title":"A revised methodology for aortic-valvar complex calcium quantification for transcatheter aortic valve implantation","volume":"15","author":"Jilaihawi","year":"2014","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jcct.2026.07.012_bib35","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1093\/ejcts\/ezaa424","article-title":"A new calcium score to predict paravalvular leak in transcatheter aortic valve implantation","volume":"59","author":"Kofler","year":"2021","journal-title":"Eur J Cardio Thorac Surg"}],"container-title":["Journal of Cardiovascular Computed Tomography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934592526004600?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1934592526004600?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T11:26:11Z","timestamp":1789212371000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1934592526004600"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":35,"alternative-id":["S1934592526004600"],"URL":"https:\/\/doi.org\/10.1016\/j.jcct.2026.07.012","relation":{},"ISSN":["1934-5925"],"issn-type":[{"value":"1934-5925","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Radiomics-based characterization of valvular calcium improves risk stratification for paravalvular regurgitation after TAVI","name":"articletitle","label":"Article Title"},{"value":"Journal of Cardiovascular Computed Tomography","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcct.2026.07.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of Society of Cardiovascular Computed Tomography.","name":"copyright","label":"Copyright"}]}}