{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T05:48:32Z","timestamp":1789710512612,"version":"4.0.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jcehepatology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical and Experimental Hepatology"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.jceh.2016.05.003","type":"journal-article","created":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T13:48:17Z","timestamp":1464097697000},"page":"203-208","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Progressive Familial Intrahepatic Cholestasis (PFIC) in Indian Children: Clinical Spectrum and Outcome"],"prefix":"10.1016","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7851-4429","authenticated-orcid":false,"given":"Sajan","family":"Agarwal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6275-7736","authenticated-orcid":false,"given":"Bikrant Bihari","family":"Lal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh","family":"Rawat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archana","family":"Rastogi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kishore G.S.","family":"Bharathy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seema","family":"Alam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jceh.2016.05.003_bib0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1750-1172-4-1","article-title":"Progressive familial intrahepatic cholestasis","volume":"4","author":"Davit-Spraul","year":"2009","journal-title":"Orphanet J Rare Dis"},{"issue":"1","key":"10.1016\/j.jceh.2016.05.003_bib0150","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1001\/archpedi.1969.02100030114014","article-title":"Byler disease: fatal familial intrahepatic cholestasis in an Amish kindred","volume":"117","author":"Clayton","year":"1969","journal-title":"Am J Dis Child"},{"issue":"12","key":"10.1016\/j.jceh.2016.05.003_bib0155","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1007\/s13312-010-0174-3","article-title":"Alpha 1 antitrypsin deficiency in children with chronic liver disease in North India","volume":"47","author":"Arora","year":"2010","journal-title":"Indian Pediatr"},{"key":"10.1016\/j.jceh.2016.05.003_bib0160","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1651-2227.2001.tb00261.x","article-title":"Aetiological factors in neonatal cholestasis","volume":"90","author":"Fischler","year":"2001","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jceh.2016.05.003_bib0165","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1111\/j.1651-2227.2009.01338.x","article-title":"Neonatal cholestasis: differentiation of biliary atresia from neonatal hepatitis in a developing country","volume":"98","author":"Poddar","year":"2009","journal-title":"Acta Paediatr"},{"issue":"suppl 1","key":"10.1016\/j.jceh.2016.05.003_bib0170","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1016\/S2210-7401(12)70018-9","article-title":"Progressive familial intrahepatic cholestasis","volume":"36","author":"Jacquemin","year":"2012","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"10.1016\/j.jceh.2016.05.003_bib0175","first-page":"570","article-title":"Progressive familial intrahepatic cholestasis","volume":"9","author":"Hori","year":"2010","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"10.1016\/j.jceh.2016.05.003_bib0180","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/hep.510260121","article-title":"Genetic and morphological findings in progressive familial intrahepatic cholestasis (Byler disease [PFIC 1] and Byler syndrome): evidence for heterogenicity","volume":"26","author":"Bull","year":"1997","journal-title":"Hepatology"},{"key":"10.1016\/j.jceh.2016.05.003_bib0185","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jceh.2013.10.005","article-title":"Progressive familial intrahepatic cholestasis","volume":"4","author":"Srivastava","year":"2014","journal-title":"J Clin Exp Hepatol"},{"key":"10.1016\/j.jceh.2016.05.003_bib0190","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1007\/s00383-014-3559-x","article-title":"Outcome of partial internal biliary diversion for intractable pruritus in children with cholestatic liver disease","volume":"30","author":"Ramachandran","year":"2014","journal-title":"Pediatr Surg Int"},{"key":"10.1016\/j.jceh.2016.05.003_bib0195","doi-asserted-by":"crossref","first-page":"212","DOI":"10.4103\/1319-3767.80387","article-title":"Partial internal biliary diversion: a solution for intractable pruritus in progressive familial intrahepatic cholestasis type 1","volume":"17","author":"Ganesh","year":"2011","journal-title":"Saudi J Gastroenterol"},{"key":"10.1016\/j.jceh.2016.05.003_bib0200","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1007\/s13312-010-0122-2","article-title":"Cholecystoappendicostomy for progressive familial intrahepatic cholestasis","volume":"47","author":"Sharma","year":"2010","journal-title":"Indian Pediatr"},{"key":"10.1016\/j.jceh.2016.05.003_bib0205","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1007\/s12098-011-0516-8","article-title":"Therapeutic interventions in progressive familial intrahepatic cholestasis: experience from a tertiary care centre in north India","volume":"79","author":"Kaur","year":"2012","journal-title":"Indian J Pediatr"},{"issue":"3","key":"10.1016\/j.jceh.2016.05.003_bib0210","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.1365-2133.2009.09586.x","article-title":"The 5-D itch scale: a new measure of pruritus","volume":"162","author":"Elman","year":"2010","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jceh.2016.05.003_bib0215","series-title":"Guideline Updates on the Management of Severe Acute Malnutrition in Infants and Children","author":"WHO","year":"2013"},{"key":"10.1016\/j.jceh.2016.05.003_bib0220","first-page":"845","article-title":"Consensus report on neonatal cholestasis syndrome. Pediatric Gastroenterology Subspecialty Chapter of Indian Academy of Pediatrics","volume":"37","year":"2000","journal-title":"Indian Pediatr"},{"key":"10.1016\/j.jceh.2016.05.003_bib0225","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jhep.2010.01.034","article-title":"Differences in presentation and progression between severe FIC1 and BSEP deficiencies","volume":"53","author":"Pawlikowska","year":"2010","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2016.05.003_bib0230","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1002\/hep.23539","article-title":"ATP8B1 and ABCB11 analysis in 62 children with normal GGT progressive familial intrahepatic cholestasis (PFIC): phenotypic differences between PFIC1 and PFIC2 and natural history","volume":"51","author":"Davit-Spraul","year":"2010","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.jceh.2016.05.003_bib0235","first-page":"179","article-title":"Genetic cholestatic liver diseases: the example of progressive familial intrahepatic cholestasis and related disorders","volume":"64","author":"Baussan","year":"2004","journal-title":"Acta Gastroenterol Belg"},{"issue":"7","key":"10.1016\/j.jceh.2016.05.003_bib0240","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1136\/gut.52.7.1025","article-title":"Genetic evidence of heterogeneity in intrahepatic cholestasis of pregnancy","volume":"52","author":"Savander","year":"2003","journal-title":"Gut"},{"issue":"3","key":"10.1016\/j.jceh.2016.05.003_bib0245","first-page":"216","article-title":"Progressive familial intrahepatic cholestasis in Malaysian patients\u2014a report of five cases","volume":"64","author":"Lee","year":"2009","journal-title":"Med J Malaysia"},{"key":"10.1016\/j.jceh.2016.05.003_bib0250","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.jpedsurg.2008.07.018","article-title":"Non-transplant surgical interventions in progressive familial intrahepatic cholestasis","volume":"44","author":"Davis","year":"2009","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jceh.2016.05.003_bib0255","first-page":"433","article-title":"Laparoscopic button cholecystostomy for progressive familial intrahepatic cholestasis in two children","volume":"24","author":"Schukfeh","year":"2014","journal-title":"Eur J Pediatr Surg"},{"key":"10.1016\/j.jceh.2016.05.003_bib0260","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/j.1399-3046.2007.00722.x","article-title":"Liver transplantation for progressive familial intrahepatic cholestasis: clinical and histopathological findings, outcome and impact on growth","volume":"11","author":"Aydogdu","year":"2007","journal-title":"Pediatr Transplant"},{"key":"10.1016\/j.jceh.2016.05.003_bib0265","doi-asserted-by":"crossref","first-page":"3003","DOI":"10.1016\/j.transproceed.2003.10.047","article-title":"Living related liver transplantation in 13 cases of progressive familial intrahepatic cholestasis","volume":"35","author":"Bassas","year":"2003","journal-title":"Transplant Proc"},{"key":"10.1016\/j.jceh.2016.05.003_bib0270","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0168-8278(03)00286-1","article-title":"Progressive familial intrahepatic cholestasis type 1 and extrahepatic features: no catch-up of stature growth, exacerbation of diarrhea, and appearance of liver steatosis after liver transplantation","volume":"39","author":"Lykavieris","year":"2003","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2016.05.003_bib0275","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1053\/jlts.2002.34384","article-title":"Intractable diarrhoea after liver transplantation for Byler's disease: successful treatment with bile adsorptive resin","volume":"8","author":"Egawa","year":"2002","journal-title":"Liver Transplant"},{"key":"10.1016\/j.jceh.2016.05.003_bib0280","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.jhep.2010.05.025","article-title":"Relapsing features of bile salt export pump deficiency after liver transplantation in two patients with progressive familial intrahepatic cholestasis type 2","volume":"53","author":"Maggiore","year":"2010","journal-title":"J Hepatol"}],"container-title":["Journal of Clinical and Experimental Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688316300585?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688316300585?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T06:03:42Z","timestamp":1760853822000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0973688316300585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S0973688316300585"],"URL":"https:\/\/doi.org\/10.1016\/j.jceh.2016.05.003","relation":{},"ISSN":["0973-6883"],"issn-type":[{"value":"0973-6883","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Progressive Familial Intrahepatic Cholestasis (PFIC) in Indian Children: Clinical Spectrum and Outcome","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical and Experimental Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jceh.2016.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 INASL.","name":"copyright","label":"Copyright"}]}}