{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T19:15:52Z","timestamp":1747163752515,"version":"3.40.5"},"reference-count":23,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","jcehepatology.com","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical and Experimental Hepatology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.jceh.2024.101409","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T16:26:33Z","timestamp":1712593593000},"page":"101409","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Adipokine (adiponectin-rs1501299) Gene Variant and Patient Characteristics in Relation to Metabolic-associated Fatty Liver Disease"],"prefix":"10.1016","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2014-2239","authenticated-orcid":false,"given":"Amal A.","family":"Mohamed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8568-1033","authenticated-orcid":false,"given":"Soha","family":"Hassanin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed A.","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7201-3658","authenticated-orcid":false,"given":"Dalia","family":"Zaafar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1641-6807","authenticated-orcid":false,"given":"Rasha","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5127-5379","authenticated-orcid":false,"given":"Mohamed B.","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1352-0948","authenticated-orcid":false,"given":"Al-Shaymaa A.","family":"Hassanin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1004-6419","authenticated-orcid":false,"given":"Eman","family":"Alsayed Abouahmad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed A.","family":"Sakr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soha M.","family":"Abd el salam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5365-2630","authenticated-orcid":false,"given":"Reem A.M.","family":"Abdelghafour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nashwa M.","family":"Muharram","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marwa K.","family":"Darwish","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saadia","family":"faried","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karmia","family":"Nasraldin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1203-0808","authenticated-orcid":false,"given":"Wael","family":"Hafez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jceh.2024.101409_bib1","first-page":"9050","article-title":"Epidemiology of fatty liver: an update","volume":"20","author":"Bedogni","year":"2014","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.jceh.2024.101409_bib2","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/hep.28431","article-title":"Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes","volume":"64","author":"Younossi","year":"2016","journal-title":"Hepatology"},{"key":"10.1016\/j.jceh.2024.101409_bib3","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1053\/jhep.2003.50229","article-title":"Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values","volume":"37","author":"Mofrad","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.jceh.2024.101409_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0224626","article-title":"Nonalcoholic fatty liver disease is an early predictor of metabolic diseases in a metabolically healthy population","volume":"14","author":"Yang","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.jceh.2024.101409_bib5","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/jgh.13264","article-title":"Nonalcoholic fatty liver disease is associated with an almost twofold increased risk of incident type 2 diabetes and metabolic syndrome. Evidence from a systematic review and meta-analysis","volume":"31","author":"Ballestri","year":"2016","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1016\/j.jceh.2024.101409_bib6","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s12916-017-0806-8","article-title":"Non-alcoholic fatty liver disease","volume":"15","author":"Neuschwander-Tetri","year":"2017","journal-title":"BMC Med"},{"key":"10.1016\/j.jceh.2024.101409_bib7","doi-asserted-by":"crossref","first-page":"850","DOI":"10.3389\/fphys.2020.00850","article-title":"Lipophagy impairment is associated with disease progression in NAFLD","volume":"11","author":"Carotti","year":"2020","journal-title":"Front Physiol"},{"key":"10.1016\/j.jceh.2024.101409_bib8","doi-asserted-by":"crossref","first-page":"65","DOI":"10.34172\/mejdd.2020.166","article-title":"Assessment of genetic aspects of non-alcoholic fatty liver and premature cardiovascular events","volume":"12","author":"Saki","year":"2020","journal-title":"Middle East J Dig Dis"},{"key":"10.1016\/j.jceh.2024.101409_bib9","doi-asserted-by":"crossref","first-page":"140","DOI":"10.3389\/fgene.2016.00140","article-title":"Additive effects of the risk alleles of PNPLA3 and TM6SF2 on non-alcoholic fatty liver disease (NAFLD) in a Chinese population","volume":"7","author":"Wang","year":"2016","journal-title":"Front Genet"},{"key":"10.1016\/j.jceh.2024.101409_bib10","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1007\/s10038-008-0303-1","article-title":"Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity","volume":"53","author":"Kyriakou","year":"2008","journal-title":"J\u00a0Hum Genet"},{"key":"10.1016\/j.jceh.2024.101409_bib11","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/sj.ejhg.5201120","article-title":"Association of the human adiponectin gene and insulin resistance","volume":"12","author":"Filippi","year":"2004","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.jceh.2024.101409_bib12","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1007\/s10620-016-4134-1","article-title":"Screening strategies for nonalcoholic steatohepatitis in high-risk individuals: trimming away the fat","volume":"61","author":"Vuppalanchi","year":"2016","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.jceh.2024.101409_bib13","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1007\/s00109-005-0667-z","article-title":"The adiponectin gene SNP+276G>T associates with early-onset coronary artery disease and with lower levels of adiponectin in younger coronary artery disease patients (age <or=50 years)","volume":"83","author":"Filippi","year":"2005","journal-title":"J\u00a0Mol Med (Berl)"},{"key":"10.1016\/j.jceh.2024.101409_bib14","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1159\/000453401","article-title":"rs1501299 polymorphism in the adiponectin gene and their association with total adiponectin levels, insulin resistance and metabolic syndrome in obese subjects","volume":"69","author":"de Luis","year":"2016","journal-title":"Ann Nutr Metab"},{"key":"10.1016\/j.jceh.2024.101409_bib15","doi-asserted-by":"crossref","DOI":"10.5812\/hepatmon.9527","article-title":"Association of adiponectin rs1501299 and rs266729 gene polymorphisms with nonalcoholic fatty liver disease","volume":"13","author":"Hashemi","year":"2013","journal-title":"Hepat Mon"},{"key":"10.1016\/j.jceh.2024.101409_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2021.e07851","article-title":"Adiponectin gene polymorphisms associated with diabetes mellitus: a descriptive review","volume":"7","author":"Howlader","year":"2021","journal-title":"Heliyon"},{"key":"10.1016\/j.jceh.2024.101409_bib17","first-page":"155","article-title":"Major components of metabolic parameters and nutritional intakes in different genotypes of adiponectin\u00a0+276 G>T gene polymorphism in non-diabetes and non-alcoholic Iranian fatty liver patients","volume":"9","author":"Mohseni","year":"2017","journal-title":"Avicenna J Med Biotechnol (AJMB)"},{"key":"10.1016\/j.jceh.2024.101409_bib18","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1093\/ajcn\/82.4.760","article-title":"Association of the 276G->T polymorphism of the adiponectin gene with cardiovascular disease risk factors in nondiabetic Koreans","volume":"82","author":"Jang","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jceh.2024.101409_bib19","first-page":"459","article-title":"Metabolic predictors and vitamin D deficiency in patients with type 2 diabetes mellitus","volume":"15","author":"Aludwan","year":"2019","journal-title":"Internet J Endocrinol"},{"key":"10.1016\/j.jceh.2024.101409_bib20","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2020-039804","article-title":"Relationship between triglyceride glucose index and the incidence of non-alcoholic fatty liver disease in the elderly: a retrospective cohort study in China","volume":"10","author":"Huanan","year":"2020","journal-title":"BMJ Open"},{"key":"10.1016\/j.jceh.2024.101409_bib21","first-page":"37","article-title":"Recent advances in non-invasive diagnosis and medical management of non-alcoholic fatty liver disease in adult","volume":"10","author":"Jayanta","year":"2020","journal-title":"EGLJ"},{"key":"10.1016\/j.jceh.2024.101409_bib22","first-page":"Cr735","article-title":"The BARD score and the NAFLD fibrosis score in the assessment of advanced liver fibrosis in nonalcoholic fatty liver disease","volume":"18","author":"Cicho\u017c-Lach","year":"2012","journal-title":"Med Sci Mon Int Med J Exp Clin Res"},{"key":"10.1016\/j.jceh.2024.101409_bib23","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.798417","article-title":"Correlation of adiponectin gene polymorphisms rs266729 and rs3774261 with risk of nonalcoholic fatty liver disease: a systematic review and meta-analysis","volume":"13","author":"Zheng","year":"2022","journal-title":"Front Endocrinol"}],"container-title":["Journal of Clinical and Experimental Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688324000665?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688324000665?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T22:44:31Z","timestamp":1725576271000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0973688324000665"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S0973688324000665"],"URL":"https:\/\/doi.org\/10.1016\/j.jceh.2024.101409","relation":{},"ISSN":["0973-6883"],"issn-type":[{"type":"print","value":"0973-6883"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adipokine (adiponectin-rs1501299) Gene Variant and Patient Characteristics in Relation to Metabolic-associated Fatty Liver Disease","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical and Experimental Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jceh.2024.101409","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Indian National Association for Study of the Liver. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101409"}}