{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:58Z","timestamp":1779148858462,"version":"3.51.4"},"reference-count":16,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","jcehepatology.com","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical and Experimental Hepatology"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.jceh.2024.102484","type":"journal-article","created":{"date-parts":[[2024,12,7]],"date-time":"2024-12-07T16:23:27Z","timestamp":1733588607000},"page":"102484","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Glycerol-3-Phosphate Dehydrogenase 1 Deficiency and Steatotic Liver Disease in Children: Our Cases and Review of Literature"],"prefix":"10.1016","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4641-1426","authenticated-orcid":false,"given":"Ankit","family":"Agrawal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0902-4140","authenticated-orcid":false,"given":"Anshu","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amita","family":"Moirangthem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzena M.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhriti","family":"Kodethoor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3520-3046","authenticated-orcid":false,"given":"Srinivas S.","family":"Vadlapudi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2015-4069","authenticated-orcid":false,"given":"Moinak S.","family":"Sarma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5277-4401","authenticated-orcid":false,"given":"Ujjal","family":"Poddar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jceh.2024.102484_bib1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.ajhg.2011.11.028","article-title":"Transient infantile hypertriglyceridemia, fatty liver, and hepatic fibrosis caused by mutated GPD1, encoding glycerol-3-phosphate dehydrogenase 1","volume":"90","author":"Basel-Vanagaite","year":"2012","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jceh.2024.102484_bib2","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1038\/ejhg.2014.8","article-title":"A\u00a0compound heterozygous mutation in GPD1 causes hepatomegaly, steatohepatitis, and hypertriglyceridemia","volume":"22","author":"Joshi","year":"2014","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.jceh.2024.102484_bib3","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s10545-016-9956-7","article-title":"Expanding the molecular diversity and phenotypic spectrum of glycerol 3-phosphate dehydrogenase 1 deficiency","volume":"39","author":"Dionisi-Vici","year":"2016","journal-title":"J\u00a0Inherit Metab Dis"},{"key":"10.1016\/j.jceh.2024.102484_bib4","doi-asserted-by":"crossref","first-page":"3189","DOI":"10.1002\/ajmg.a.38473","article-title":"Biallelic mutations in GPD1 gene in a Chinese boy mainly presented with obesity, insulin resistance, fatty liver, and short stature","volume":"173","author":"Li","year":"2017","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.jceh.2024.102484_bib5","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s12876-018-0827-6","article-title":"A\u00a0novel homozygous mutation in the glycerol-3-phosphate dehydrogenase 1 gene in a Chinese patient with transient infantile hypertriglyceridemia: a case report","volume":"18","author":"Li","year":"2018","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.jceh.2024.102484_bib6","first-page":"25","article-title":"Successful fenofibrate therapy for severe and persistent hypertriglyceridemia in a boy with cirrhosis and glycerol-3-phosphate dehydrogenase 1 deficiency","volume":"54","author":"Matarazzo","year":"2020","journal-title":"JIMD Rep"},{"key":"10.1016\/j.jceh.2024.102484_bib7","first-page":"923","article-title":"[Transient infantile hypertriglyceridemia caused by GPD1 deficiency: report of two cases and literature review]","volume":"58","author":"Xie","year":"2020","journal-title":"Zhonghua Er Ke Za Zhi"},{"key":"10.1016\/j.jceh.2024.102484_bib8","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1007\/s12098-020-03385-x","article-title":"GPD1 deficiency - underdiagnosed cause of liver disease","volume":"88","author":"Tesarova","year":"2021","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.jceh.2024.102484_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2021.726116","article-title":"Case report: identification of a novel homozygous mutation in GPD1 gene of a Chinese child with transient infantile hypertriglyceridemia","volume":"12","author":"Lin","year":"2021","journal-title":"Front Genet"},{"key":"10.1016\/j.jceh.2024.102484_bib10","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s12098-021-03663-2","article-title":"Transient infantile hypertriglyceridemia and hepatic steatosis in an infant with GPD1 mutation","volume":"88","author":"Kumar","year":"2021","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.jceh.2024.102484_bib11","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1159\/000523764","article-title":"Rare transient infantile hypertriglyceridemia with hypoglycemia and insulin resistance caused by a novel GPD1 mutation","volume":"13","author":"Tan","year":"2022","journal-title":"Mol Syndromol"},{"key":"10.1016\/j.jceh.2024.102484_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jceh.2023.09.009","article-title":"A\u00a0novel cause of massive hepatosplenomegaly with fibrosis in two children: transient infantile hypertriglyceridemia","volume":"14","author":"Sharma","year":"2024","journal-title":"J\u00a0Clin Exp Hepatol"},{"key":"10.1016\/j.jceh.2024.102484_bib13","article-title":"Transient infantile hypertriglyceridemia with jaundice: a case report","volume":"100","author":"Wang","year":"2021","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.jceh.2024.102484_bib14","doi-asserted-by":"crossref","first-page":"9441","DOI":"10.1074\/jbc.275.13.9441","article-title":"Induction of the peroxisomal glycerolipid-synthesizing enzymes during differentiation of 3T3-L1 adipocytes: role in triacylglycerol synthesis","volume":"275","author":"Hajra","year":"2000","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.jceh.2024.102484_bib15","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1542\/pir.2016-0138","article-title":"Approach to hypertriglyceridemia in the pediatric population","volume":"38","author":"Valaiyapathi","year":"2017","journal-title":"Pediatr Rev"},{"key":"10.1016\/j.jceh.2024.102484_bib16","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1016\/j.numecd.2024.02.006","article-title":"Long-term clinical outcomes and management of hypertriglyceridemia in children with Apo-CII deficiency","volume":"34","author":"Celik","year":"2024","journal-title":"Nutr Metabol Cardiovasc Dis"}],"container-title":["Journal of Clinical and Experimental Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688324011514?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688324011514?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T22:50:10Z","timestamp":1746226210000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0973688324011514"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["S0973688324011514"],"URL":"https:\/\/doi.org\/10.1016\/j.jceh.2024.102484","relation":{},"ISSN":["0973-6883"],"issn-type":[{"value":"0973-6883","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Glycerol-3-Phosphate Dehydrogenase 1 Deficiency and Steatotic Liver Disease in Children: Our Cases and Review of Literature","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical and Experimental Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jceh.2024.102484","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Indian National Association for Study of the Liver. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102484"}}