{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T21:32:17Z","timestamp":1763415137989,"version":"3.45.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jcehepatology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical and Experimental Hepatology"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.jceh.2025.102598","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T19:20:02Z","timestamp":1747941602000},"page":"102598","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lifestyle Intervention is Effective in Reversal of Fibrosis in NAFLD Patients: Results from a Retrospective Real-World Study"],"prefix":"10.1016","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8197-2674","authenticated-orcid":false,"given":"Shivaram P.","family":"Singh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4494-0865","authenticated-orcid":false,"given":"Prajna","family":"Anirvan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6646-0857","authenticated-orcid":false,"given":"Swati","family":"Chouhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9540-3686","authenticated-orcid":false,"given":"Manas K.","family":"Panigrahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chitta R.","family":"Khatua","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir","family":"Hota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6167-0778","authenticated-orcid":false,"given":"Mitali M.","family":"Rath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjib K.","family":"Kar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bijay","family":"Misra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Preetam","family":"Nath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9091-1657","authenticated-orcid":false,"given":"Saroj K.","family":"Sahu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jimmy","family":"Narayan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayaskanta","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jceh.2025.102598_bib1","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.jceh.2021.11.010","article-title":"Prevalence of non-alcoholic fatty liver disease in India: a systematic review and meta-analysis","volume":"12","author":"Shalimar","year":"2022","journal-title":"J Clin Exp Hepatol"},{"key":"10.1016\/j.jceh.2025.102598_bib2","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.jhep.2012.12.005","article-title":"The burden of liver disease in Europe: a review of available epidemiological data","volume":"58","author":"Blachier","year":"2013","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2025.102598_bib3","first-page":"691","article-title":"MASLD: a systemic metabolic disorder with cardiovascular and malignant complications","volume":"73","author":"Targher","year":"2024","journal-title":"Gut"},{"key":"10.1016\/j.jceh.2025.102598_bib4","article-title":"Management of cardiovascular risk in the non-alcoholic fatty liver disease setting","volume":"19","author":"Linero","year":"2024","journal-title":"Eur Cardiol"},{"key":"10.1016\/j.jceh.2025.102598_bib5","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1053\/j.gastro.2020.11.051","article-title":"AGA clinical practice update on lifestyle modification using diet and exercise to achieve weight loss in the management of nonalcoholic fatty liver disease: expert review","volume":"160","author":"Younossi","year":"2021","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jceh.2025.102598_bib6","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1161\/CIRCULATIONAHA.111.039453","article-title":"Lifestyle modification for obesity: new developments in diet, physical activity, and behavior therapy","volume":"125","author":"Wadden","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.jceh.2025.102598_bib7","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1097\/HEP.0000000000000323","article-title":"AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease","volume":"77","author":"Rinella","year":"2023","journal-title":"Hepatology"},{"key":"10.1016\/j.jceh.2025.102598_bib8","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/j.jhep.2015.11.004","article-title":"Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease","volume":"64","year":"2016","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2025.102598_bib9","article-title":"Physical activity guidelines for Americans","volume":"3","author":"Olson","year":"2023","journal-title":"NADAR! SWIMMING MAGAZINE-Peri\u00f3dico cient\u00edfico em esportes e fitness aqu\u00e1tico-nata\u00e7\u00e3o, p\u00f3lo aqu\u00e1tico, nado sincronizado, saltos ornamentais, travessias aqu\u00e1ticas"},{"key":"10.1016\/j.jceh.2025.102598_bib10","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0168-8278(97)80287-5","article-title":"Therapeutic effects of restricted diet and exercise in obese patients with fatty liver","volume":"27","author":"Ueno","year":"1997","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2025.102598_bib11","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1053\/j.gastro.2015.04.005","article-title":"Weight loss through lifestyle modification significantly reduces features of nonalcoholic steatohepatitis","volume":"149","author":"Vilar-Gomez","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jceh.2025.102598_bib12","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.jhep.2013.04.013","article-title":"Community-based lifestyle modification programme for non-alcoholic fatty liver disease: a randomized controlled trial","volume":"59","author":"Wong","year":"2013","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2025.102598_bib13","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1111\/j.1365-2036.2009.04122.x","article-title":"Clinical trial: a nutritional supplement Viusid, in combination with diet and exercise, in patients with nonalcoholic fatty liver disease","volume":"30","author":"Vilar Gomez","year":"2009","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.jceh.2025.102598_bib14","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/hep.29367","article-title":"The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases","volume":"67","author":"Chalasani","year":"2018","journal-title":"Hepatology"},{"key":"10.1016\/j.jceh.2025.102598_bib15","doi-asserted-by":"crossref","first-page":"S186","DOI":"10.1046\/j.1440-1746.17.s1.10.x","article-title":"Non-alcoholic fatty liver disease","volume":"17","author":"Angulo","year":"2002","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.jceh.2025.102598_bib16","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1148\/radiol.2020192437","article-title":"Update to the society of radiologists in ultrasound liver elastography consensus statement","volume":"296","author":"Barr","year":"2020","journal-title":"Radiology"},{"key":"10.1016\/j.jceh.2025.102598_bib17","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.jhep.2010.05.035","article-title":"Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: a multicenter prospective study (the FIBROSTIC study)","volume":"53","author":"Degos","year":"2010","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2025.102598_bib18","doi-asserted-by":"crossref","DOI":"10.3390\/nu11122971","article-title":"Mediterranean diet and NAFLD: what we know and questions that still need to be answered","volume":"11","author":"Plaz Torres","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.jceh.2025.102598_bib19","doi-asserted-by":"crossref","first-page":"730","DOI":"10.14218\/JCTH.2021.00494","article-title":"Current evidence concerning effects of ketogenic diet and intermittent fasting in patients with nonalcoholic fatty liver","volume":"10","author":"Sripongpun","year":"2022","journal-title":"J Clin Transl Hepatol"},{"key":"10.1016\/j.jceh.2025.102598_bib20","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/liv.12990","article-title":"The effects of DASH diet on weight loss and metabolic status in adults with non-alcoholic fatty liver disease: a randomized clinical trial","volume":"36","author":"Razavi Zade","year":"2016","journal-title":"Liver Int"},{"key":"10.1016\/j.jceh.2025.102598_bib21","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2023.3513","article-title":"Effects of time-restricted eating on nonalcoholic fatty liver disease: the TREATY-FLD randomized clinical trial","volume":"6","author":"Wei","year":"2023","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.jceh.2025.102598_bib22","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.jhep.2011.12.011","article-title":"Predictors for incidence and remission of NAFLD in the general population during a seven-year prospective follow-up","volume":"56","author":"Zelber-Sagi","year":"2012","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2025.102598_bib23","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/jgh.14360","article-title":"Lean non-alcoholic fatty liver disease patients had comparable total caloric, carbohydrate, protein, fat, iron, sleep duration and overtime work as obese non-alcoholic fatty liver disease patients","volume":"34","author":"Li","year":"2019","journal-title":"J Gastroenterol Hepatol"},{"issue":"suppl 4","key":"10.1016\/j.jceh.2025.102598_bib24","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/jgh.12244","article-title":"Role of diet and nutritional management in non-alcoholic fatty liver disease","volume":"28","author":"Fan","year":"2013","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.jceh.2025.102598_bib25","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1056\/NEJMoa0804748","article-title":"Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates","volume":"360","author":"Sacks","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jceh.2025.102598_bib26","doi-asserted-by":"crossref","first-page":"120","DOI":"10.14218\/JCTH.2019.00012","article-title":"Effect of exercise on NAFLD and its risk factors: comparison of moderate versus low intensity exercise","volume":"8","author":"Nath","year":"2020","journal-title":"J Clin Transl Hepatol"}],"container-title":["Journal of Clinical and Experimental Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688325000982?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688325000982?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T17:14:20Z","timestamp":1763399660000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0973688325000982"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S0973688325000982"],"URL":"https:\/\/doi.org\/10.1016\/j.jceh.2025.102598","relation":{},"ISSN":["0973-6883"],"issn-type":[{"type":"print","value":"0973-6883"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lifestyle Intervention is Effective in Reversal of Fibrosis in NAFLD Patients: Results from a Retrospective Real-World Study","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical and Experimental Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jceh.2025.102598","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Indian National Association for Study of the Liver. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102598"}}