{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T00:27:13Z","timestamp":1793924833550,"version":"4.8.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jcehepatology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical and Experimental Hepatology"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.jceh.2026.103550","type":"journal-article","created":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T15:09:34Z","timestamp":1776352174000},"page":"103550","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Molecular Biomarkers and Risk Prediction Models for Acute Kidney Injury Following Liver Transplantation: A Review"],"prefix":"10.1016","volume":"16","author":[{"given":"Bing","family":"Bin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxiao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shijian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihua","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jceh.2026.103550_bib1","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/bja\/aeu556","article-title":"Acute kidney injury following orthotopic liver transplantation: incidence, risk factors, and effects on patient and graft survival","volume":"114","author":"Hilmi","year":"2015","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jceh.2026.103550_bib2","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.6002\/ect.2021.0300","article-title":"Acute kidney injury after liver transplant: incidence, risk factors, and impact on patient outcomes","volume":"19","author":"Hizomi Arani","year":"2021","journal-title":"Exp Clin Transplant"},{"key":"10.1016\/j.jceh.2026.103550_bib3","first-page":"1","article-title":"KDIGO clinical practice guideline for acute kidney injury","volume":"2","year":"2012","journal-title":"Kidney Int Suppl"},{"key":"10.1016\/j.jceh.2026.103550_bib4","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1097\/TP.0000000000002305","article-title":"Acute kidney injury after liver transplantation","volume":"102","author":"Durand","year":"2018","journal-title":"Transplantation"},{"key":"10.1016\/j.jceh.2026.103550_bib5","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1186\/s12882-021-02360-8","article-title":"Modifiable risk factors of acute kidney injury after liver transplantation: a systematic review and meta-analysis","volume":"22","author":"Zhou","year":"2021","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.jceh.2026.103550_bib6","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1002\/lt.26094","article-title":"Post-liver transplant acute kidney injury","volume":"27","author":"Dong","year":"2021","journal-title":"Liver Transpl"},{"issue":"5","key":"10.1016\/j.jceh.2026.103550_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0064089","article-title":"Role of MELD score and serum creatinine as prognostic tools for the development of acute kidney injury after liver transplantation","volume":"8","author":"Romano","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jceh.2026.103550_bib8","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1097\/SLA.0b013e3182365081","article-title":"Are there better guidelines for allocation in liver transplantation? A novel score targeting justice and utility in the model for end-stage liver disease era","volume":"254","author":"Dutkowski","year":"2011","journal-title":"Ann Surg"},{"key":"10.1016\/j.jceh.2026.103550_bib9","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1001\/jamasurg.2022.1548","article-title":"Proposing a sex-adjusted sodium-adjusted MELD score for liver transplant allocation","volume":"157","author":"Sealock","year":"2022","journal-title":"JAMA Surg"},{"key":"10.1016\/j.jceh.2026.103550_bib10","doi-asserted-by":"crossref","first-page":"4572130","DOI":"10.1155\/2019\/4572130","article-title":"Intraoperative hepatic blood inflow can predict early acute kidney injury following DCD liver transplantation: a retrospective observational study","volume":"2019","author":"Jiao","year":"2019","journal-title":"BioMed Res Int"},{"key":"10.1016\/j.jceh.2026.103550_bib11","doi-asserted-by":"crossref","DOI":"10.1080\/07853890.2023.2259410","article-title":"Development of a nomogram for the prediction of acute kidney injury after liver transplantation: a model based on clinical parameters and postoperative cystatin C level","volume":"55","author":"Wu","year":"2023","journal-title":"Ann Med"},{"key":"10.1016\/j.jceh.2026.103550_bib12","doi-asserted-by":"crossref","first-page":"10887","DOI":"10.3389\/ti.2023.10887","article-title":"A novel online calculator predicting acute kidney injury after liver transplantation: a retrospective study","volume":"36","author":"Zeng","year":"2023","journal-title":"Transpl Int"},{"key":"10.1016\/j.jceh.2026.103550_bib13","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3390\/jcm8010029","article-title":"Intraoperative oliguria with decreased SvO2 predicts acute kidney injury after living donor liver transplantation","volume":"8","author":"Kim","year":"2018","journal-title":"J Clin Med"},{"key":"10.1016\/j.jceh.2026.103550_bib14","article-title":"Clinical risk scoring models for prediction of acute kidney injury after living donor liver transplantation: a retrospective observational study","volume":"10","author":"Park","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jceh.2026.103550_bib15","doi-asserted-by":"crossref","first-page":"41555","DOI":"10.1038\/srep41555","article-title":"Risk factors of acute kidney injury after orthotopic liver transplantation in China","volume":"7","author":"Zongyi","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jceh.2026.103550_bib16","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1186\/s12967-021-02990-4","article-title":"An explainable supervised machine learning predictor of acute kidney injury after adult deceased donor liver transplantation","volume":"19","author":"Zhang","year":"2021","journal-title":"J Transl Med"},{"key":"10.1016\/j.jceh.2026.103550_bib17","doi-asserted-by":"crossref","first-page":"570","DOI":"10.4254\/wjh.v14.i3.570","article-title":"Risk factors and prediction of acute kidney injury after liver transplantation: logistic regression and artificial neural network approaches","volume":"14","author":"Bredt","year":"2022","journal-title":"World J Hepatol"},{"key":"10.1016\/j.jceh.2026.103550_bib18","doi-asserted-by":"crossref","first-page":"6168","DOI":"10.21037\/apm-21-842","article-title":"A prediction score model and survival analysis of acute kidney injury following orthotopic liver transplantation in adults","volume":"10","author":"Bao","year":"2021","journal-title":"Ann Palliat Med"},{"key":"10.1016\/j.jceh.2026.103550_bib19","article-title":"Prediction of acute kidney injury after liver transplantation: machine learning approaches vs. logistic regression model","volume":"7","author":"Lee","year":"2018","journal-title":"J Clin Med"},{"key":"10.1016\/j.jceh.2026.103550_bib20","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.hbpd.2021.02.001","article-title":"Application of machine learning models for predicting acute kidney injury following donation after cardiac death liver transplantation","volume":"20","author":"He","year":"2021","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"10.1016\/j.jceh.2026.103550_bib21","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.jhep.2023.01.006","article-title":"Artificial intelligence, machine learning, and deep learning in liver transplantation","volume":"78","author":"Bhat","year":"2023","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2026.103550_bib22","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1080\/0886022X.2021.1945462","article-title":"Early prediction of acute kidney injury after liver transplantation by scoring system and decision tree","volume":"43","author":"Wang","year":"2021","journal-title":"Ren Fail"},{"key":"10.1016\/j.jceh.2026.103550_bib23","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1002\/lt.22158","article-title":"Neutrophil gelatinase-associated lipocalin predicts acute kidney injury in patients undergoing liver transplantation","volume":"16","author":"Portal","year":"2010","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jceh.2026.103550_bib24","first-page":"270","article-title":"Early prediction of acute kidney injury in living donor liver transplantation by serum cystatin C concentration at the end of the surgery","volume":"18","author":"Vijayakumar","year":"2024","journal-title":"Iran J Kidney Dis"},{"key":"10.1016\/j.jceh.2026.103550_bib25","doi-asserted-by":"crossref","first-page":"947","DOI":"10.2217\/bmm.13.91","article-title":"Novel biomarkers for the prediction of acute kidney injury in patients undergoing liver transplantation","volume":"7","author":"Dedeoglu","year":"2013","journal-title":"Biomark Med"},{"key":"10.1016\/j.jceh.2026.103550_bib26","doi-asserted-by":"crossref","first-page":"2402076","DOI":"10.1080\/0886022X.2024.2402076","article-title":"Comprehensive biomarker assessment for predicting severe acute kidney injury and need of kidney replacement therapy in liver transplantation patients","volume":"46","author":"Lima","year":"2024","journal-title":"Ren Fail"},{"key":"10.1016\/j.jceh.2026.103550_bib27","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1111\/ctr.12394","article-title":"Neutrophil gelatinase-associated lipocalin associated with irreversibility of pre-liver transplant kidney dysfunction","volume":"28","author":"Aberg","year":"2014","journal-title":"Clin Transplant"},{"key":"10.1016\/j.jceh.2026.103550_bib28","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1097\/MEG.0000000000001892","article-title":"Intraoperative systemic biomarkers predict post-liver transplantation acute kidney injury","volume":"33","author":"Cezar","year":"2021","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.jceh.2026.103550_bib29","doi-asserted-by":"crossref","first-page":"8643","DOI":"10.1038\/s41598-023-34372-9","article-title":"Serum neutrophil gelatinase-associated lipocalin and lactate level during surgery predict acute kidney injury and early allograft dysfunction after liver transplantation","volume":"13","author":"Cho","year":"2023","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.jceh.2026.103550_bib30","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.ejccm.2016.11.001","article-title":"Urinary neutrophil gelatinase associated lipocalin as an early marker of acute kidney injury in the recipient after liver transplantation","volume":"5","author":"El-Akabawy","year":"2017","journal-title":"Egyptian J Crit Care Med"},{"key":"10.1016\/j.jceh.2026.103550_bib31","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.hpb.2018.09.017","article-title":"Urinary neutrophil gelatinase associated lipocalins (NGALs) predict acute kidney injury post liver transplant","volume":"21","author":"Robertson","year":"2019","journal-title":"HPB"},{"key":"10.1016\/j.jceh.2026.103550_bib32","doi-asserted-by":"crossref","first-page":"8150934","DOI":"10.1155\/2018\/8256193","article-title":"Predictive role of serum cytokine profiles in acute kidney injury after living donor liver transplantation","volume":"2018","author":"Chae","year":"2018","journal-title":"Mediat Inflamm"},{"key":"10.1016\/j.jceh.2026.103550_bib33","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1002\/hep.27857","article-title":"Circulating kidney injury molecule 1 predicts prognosis and poor outcome in patients with acetaminophen-induced liver injury","volume":"62","author":"Antoine","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.jceh.2026.103550_bib34","doi-asserted-by":"crossref","first-page":"R25","DOI":"10.1186\/cc12503","article-title":"Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury","volume":"17","author":"Kashani","year":"2013","journal-title":"Crit Care"},{"key":"10.1016\/j.jceh.2026.103550_bib35","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1186\/s12882-019-1456-1","article-title":"Urinary [TIMP-2] \u00d7 [IGFBP-7] for predicting acute kidney injury in patients undergoing orthotopic liver transplantation","volume":"20","author":"Schiefer","year":"2019","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.jceh.2026.103550_bib36","doi-asserted-by":"crossref","first-page":"291","DOI":"10.12659\/AOT.914975","article-title":"Urinary and serum biomarkers for prediction of acute kidney injury in patients undergoing liver transplantation","volume":"24","author":"Lewandowska","year":"2019","journal-title":"Ann Transplant"},{"key":"10.1016\/j.jceh.2026.103550_bib37","doi-asserted-by":"crossref","first-page":"336","DOI":"10.3109\/1354750X.2012.672458","article-title":"Urinary neutrophil gelatinase-associated lipocalin and L-type fatty acid binding protein as diagnostic markers of early acute kidney injury after liver transplantation","volume":"17","author":"Li","year":"2012","journal-title":"Biomarkers"},{"key":"10.1016\/j.jceh.2026.103550_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0293844","article-title":"Soluble suppression of tumorigenicity 2 is a potential predictor of post-liver transplant renal outcomes","volume":"18","author":"Moon","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.jceh.2026.103550_bib39","article-title":"Role of proenkephalin in the diagnosis of severe and subclinical acute kidney injury during the perioperative period of liver transplantation","volume":"31","author":"Lima","year":"2022","journal-title":"Pract Lab Med"},{"key":"10.1016\/j.jceh.2026.103550_bib40","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1002\/lt.25178","article-title":"Molecular profiling of postreperfusion milieu determines acute kidney injury after liver transplantation: a prospective study","volume":"24","author":"Pulitano","year":"2018","journal-title":"Liver Transplant"},{"key":"10.1016\/j.jceh.2026.103550_bib41","doi-asserted-by":"crossref","DOI":"10.1186\/s12967-025-06695-w","article-title":"Proteomic analysis of human kidney biopsies unveils emerging acute kidney injury very early after liver graft reperfusion","volume":"23","author":"Noren","year":"2025","journal-title":"J Transl Med"},{"key":"10.1016\/j.jceh.2026.103550_bib42","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0183162","article-title":"Comparison of macrophage migration inhibitory factor and neutrophil gelatinase-associated lipocalin-2 to predict acute kidney injury after liver transplantation: an observational pilot study","volume":"12","author":"Baron-Stefaniak","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jceh.2026.103550_bib43","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1002\/hep.27346","article-title":"Plasma protein biomarkers enhance the clinical prediction of kidney injury recovery in patients undergoing liver transplantation","volume":"60","author":"Levitsky","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.jceh.2026.103550_bib44","article-title":"MicroRNA-21 (miR-21) expression in hypothermic machine perfusate may be predictive of early outcomes in kidney transplantation","volume":"11","author":"Khalid","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jceh.2026.103550_bib45","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1097\/TP.0000000000003651","article-title":"Donor-derived cell-free DNA in solid-organ transplant diagnostics: indications, limitations, and future directions","volume":"105","author":"Kataria","year":"2021","journal-title":"Transplantation"},{"key":"10.1016\/j.jceh.2026.103550_bib46","doi-asserted-by":"crossref","first-page":"741","DOI":"10.4254\/wjh.v15.i6.741","article-title":"Recent advances in pathophysiology, diagnosis and management of hepatorenal syndrome: a review","volume":"15","author":"Kiani","year":"2023","journal-title":"World J Hepatol"},{"key":"10.1016\/j.jceh.2026.103550_bib47","doi-asserted-by":"crossref","first-page":"730","DOI":"10.3350\/cmh.2024.1060","article-title":"Tracking the trajectory of kidney dysfunction in cirrhosis: the acute kidney injury: chronic kidney disease spectrum","volume":"31","author":"Girish","year":"2025","journal-title":"Clin Mol Hepatol"}],"container-title":["Journal of Clinical and Experimental Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688326000824?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688326000824?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T23:55:59Z","timestamp":1793922959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0973688326000824"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":47,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S0973688326000824"],"URL":"https:\/\/doi.org\/10.1016\/j.jceh.2026.103550","relation":{},"ISSN":["0973-6883"],"issn-type":[{"value":"0973-6883","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular Biomarkers and Risk Prediction Models for Acute Kidney Injury Following Liver Transplantation: A Review","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical and Experimental Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jceh.2026.103550","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Indian National Association for Study of the Liver. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103550"}}