{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T05:59:20Z","timestamp":1784872760218,"version":"3.55.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jcehepatology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical and Experimental Hepatology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.jceh.2026.103551","type":"journal-article","created":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T23:57:54Z","timestamp":1776383874000},"page":"103551","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Hepatitis A Virus\u2013related Acute Liver Failure\u2014A Cause for Concern?"],"prefix":"10.1016","volume":"16","author":[{"given":"Sagnik","family":"Biswas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1247-437X","authenticated-orcid":false,"family":"Shalimar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jceh.2026.103551_bib1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/s41572-023-00461-2","article-title":"Hepatitis A virus infection","volume":"9","author":"Van Damme","year":"2023","journal-title":"Nat Rev Dis Primer"},{"key":"10.1016\/j.jceh.2026.103551_bib2","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/s12664-024-01538-w","article-title":"Viral hepatitis-induced acute liver failure","volume":"43","author":"Biswas","year":"2024","journal-title":"Indian J Gastroenterol"},{"key":"10.1016\/j.jceh.2026.103551_bib3","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.3390\/v13101900","article-title":"Hepatitis A: epidemiology, high-risk groups, prevention and research on antiviral treatment","volume":"13","author":"Migueres","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.jceh.2026.103551_bib4","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.4161\/hv.20475","article-title":"Hepatitis A vaccine should receive priority in national immunization schedule in India","volume":"8","author":"Verma","year":"2012","journal-title":"Hum Vaccines Immunother"},{"key":"10.1016\/j.jceh.2026.103551_bib5","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a031708","article-title":"Natural history, clinical manifestations, and pathogenesis of hepatitis A","volume":"8","author":"Shin","year":"2018","journal-title":"Cold Spring Harb Perspect Med"},{"key":"10.1016\/j.jceh.2026.103551_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijmmb.2024.100653","article-title":"Rising trend of symptomatic infections due to hepatitis A virus infection in adolescent and adult age group: an observational study from a tertiary care liver institute in India","volume":"50","author":"Grover","year":"2024","journal-title":"Indian J Med Microbiol"},{"key":"10.1016\/j.jceh.2026.103551_bib7","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.vaccine.2021.01.038","article-title":"One or two doses of hepatitis A vaccine in universal vaccination programs in children in 2020: a systematic review","volume":"40","author":"Andani","year":"2022","journal-title":"Vaccine"},{"key":"10.1016\/j.jceh.2026.103551_bib8","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/cld.1135","article-title":"Acute liver failure: indian perspective","volume":"18","author":"Acharya","year":"2021","journal-title":"Clin Liver Dis"},{"key":"10.1016\/j.jceh.2026.103551_bib9","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.jceh.2020.11.002","article-title":"The Indian network of drug-induced liver injury: etiology, clinical features, outcome and prognostic markers in 1288 patients","volume":"11","author":"Devarbhavi","year":"2021","journal-title":"J Clin Exp Hepatol"},{"key":"10.1016\/j.jceh.2026.103551_bib10","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1053\/j.gastro.2011.12.056","article-title":"Effects of fractionated plasma separation and adsorption on survival in patients with acute-on-chronic liver failure","volume":"142","author":"Kribben","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jceh.2026.103551_bib11","doi-asserted-by":"crossref","first-page":"522","DOI":"10.7326\/0003-4819-159-8-201310150-00005","article-title":"Albumin dialysis with a noncell artificial liver support device in patients with acute liver failure: a randomized, controlled trial","volume":"159","author":"Saliba","year":"2013","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jceh.2026.103551_bib12","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.jhep.2015.08.018","article-title":"High-volume plasma exchange in patients with acute liver failure: an open randomised controlled trial","volume":"64","author":"Larsen","year":"2016","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2026.103551_bib13","article-title":"Plasma exchange does not improve overall survival in patients with acute liver failure in a real world cohort","author":"Burke","year":"2024","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2026.103551_bib14","doi-asserted-by":"crossref","first-page":"e831","DOI":"10.1016\/j.cgh.2021.01.036","article-title":"Standard-volume plasma exchange improves outcomes in patients with acute liver failure: a randomized controlled trial","volume":"20","author":"Maiwall","year":"2022","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.jceh.2026.103551_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.jceh.2025.103178","article-title":"Therapeutic plasma exchange in patients with acute liver failure: a pilot randomized controlled trial","volume":"16","author":"Swaroop","year":"2026","journal-title":"J Clin Exp Hepatol"},{"key":"10.1016\/j.jceh.2026.103551_bib16","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/LVT.0000000000000231","article-title":"Plasma exchange for acute and acute-on-chronic liver failure: a systematic review and meta-analysis","volume":"30","author":"Beran","year":"2024","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jceh.2026.103551_bib17","article-title":"Continuous renal replacement therapy in acute liver failure","volume":"15","author":"Fisher","year":"2026","journal-title":"World J Crit Care Med [Internet]"},{"key":"10.1016\/j.jceh.2026.103551_bib18","doi-asserted-by":"crossref","first-page":"426","DOI":"10.4103\/ijmr.IJMR_275_16","article-title":"Out-of-pocket expenditure due to hepatitis A disease: a study from Kollam district, Kerala, India","volume":"146","author":"Rakesh","year":"2017","journal-title":"Indian J Med Res"},{"key":"10.1016\/j.jceh.2026.103551_bib19","first-page":"352","article-title":"Rheumatologic manifestations of hepatic diseases","volume":"32","author":"Fernandes","year":"2019","journal-title":"Ann Gastroenterol"},{"key":"10.1016\/j.jceh.2026.103551_bib20","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.jceh.2023.01.008","article-title":"Shalimar. Liver transplantation for acute liver Failure- indication, prioritization, timing, and referral","volume":"13","author":"Biswas","year":"2023","journal-title":"J Clin Exp Hepatol"},{"key":"10.1016\/j.jceh.2026.103551_bib21","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1093\/ejcts\/ezy403","article-title":"Statistical primer: multivariable regression considerations and pitfalls","volume":"55","author":"Grant","year":"2019","journal-title":"Eur J Cardio Thorac Surg"},{"key":"10.1016\/j.jceh.2026.103551_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.bpg.2024.101957","article-title":"Prognostic models in acute liver failure-historic evolution and newer updates \u201cprognostic models in acute liver failure\u201d","volume":"73","author":"Panackel","year":"2024","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"10.1016\/j.jceh.2026.103551_bib23","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1136\/gutjnl-2011-301762","article-title":"Prospective derivation and validation of early dynamic model for predicting outcome in patients with acute liver failure","volume":"61","author":"Kumar","year":"2012","journal-title":"Gut"}],"container-title":["Journal of Clinical and Experimental Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688326000836?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688326000836?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T14:33:51Z","timestamp":1781966031000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0973688326000836"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S0973688326000836"],"URL":"https:\/\/doi.org\/10.1016\/j.jceh.2026.103551","relation":{},"ISSN":["0973-6883"],"issn-type":[{"value":"0973-6883","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hepatitis A Virus\u2013related Acute Liver Failure\u2014A Cause for Concern?","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical and Experimental Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jceh.2026.103551","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Indian National Association for Study of the Liver. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103551"}}