{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T21:13:39Z","timestamp":1788902019797,"version":"build-2803163510"},"reference-count":17,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jcehepatology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Clinical and Experimental Hepatology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jceh.2026.103645","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T22:43:33Z","timestamp":1787438613000},"page":"103645","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Etiological Spectrum, Outcomes, and Diagnostic Yield of Computerized Tomography of the Head in Cirrhotic Patients With Altered Mental Status"],"prefix":"10.1016","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0091-4981","authenticated-orcid":false,"given":"Amit","family":"Bagrodia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0713-5501","authenticated-orcid":false,"given":"Venkatesh","family":"Vaithiyam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6381-130X","authenticated-orcid":false,"given":"Lalit C.","family":"Kummetha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikhil","family":"Sirohi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5878-2661","authenticated-orcid":false,"given":"Barjesh","family":"C. Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7550-0358","authenticated-orcid":false,"given":"Siddharth","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev","family":"Sachdeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok","family":"Dalal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0949-2382","authenticated-orcid":false,"given":"Ujjwal","family":"Sonika","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahima","family":"Kapoor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jceh.2026.103645_bib1","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1053\/ajem.2002.35464","article-title":"Altered mental status: evaluation and etiology in the ED","volume":"20","author":"Kanich","year":"2002","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.jceh.2026.103645_bib2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.cger.2012.09.005","article-title":"Altered mental status in older emergency department patients","volume":"29","author":"Han","year":"2013","journal-title":"Clin Geriatr Med"},{"key":"10.1016\/j.jceh.2026.103645_bib3","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1097\/MOG.0b013e3283460c7d","article-title":"Complications and outcomes in chronic liver disease","volume":"27","author":"Rahimi","year":"2011","journal-title":"Curr Opin Gastroenterol"},{"key":"10.1016\/j.jceh.2026.103645_bib4","doi-asserted-by":"crossref","first-page":"695","DOI":"10.2310\/JIM.0b013e318289e254","article-title":"Altered mental status in cirrhosis: etiologies and outcomes","volume":"61","author":"Rahimi","year":"2013","journal-title":"J Investig Med"},{"key":"10.1016\/j.jceh.2026.103645_bib5","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1002\/hep.30336","article-title":"Frailty, psychoactive medications, and cognitive dysfunction are associated with poor patient-reported outcomes in cirrhosis","volume":"69","author":"Tapper","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.jceh.2026.103645_bib6","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.amjms.2016.02.022","article-title":"Overuse of head computed tomography in cirrhosis with altered mental status","volume":"351","author":"Rahimi","year":"2016","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.jceh.2026.103645_bib7","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1053\/jhep.2002.31250","article-title":"Hepatic encephalopathy\u2014definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th world congresses of gastroenterology","volume":"35","author":"Ferenci","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.jceh.2026.103645_bib8","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.jhep.2003.10.016","article-title":"Systemic inflammatory response exacerbates the neuropsychological effects of induced hyperammonemia in cirrhosis","volume":"40","author":"Shawcross","year":"2004","journal-title":"J Hepatol"},{"key":"10.1016\/j.jceh.2026.103645_bib9","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1476-5381.2009.00433.x","article-title":"Procalcitonin in sepsis and systemic inflammation: a harmful biomarker and a therapeutic target","volume":"159","author":"Becker","year":"2010","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.jceh.2026.103645_bib10","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.diagmicrobio.2014.03.029","article-title":"Serum procalcitonin and C-reactive protein levels as markers of bacterial infection in patients with liver cirrhosis: a systematic review and meta-analysis","volume":"80","author":"Lin","year":"2014","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.jceh.2026.103645_bib11","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1469-0691.2004.01044.x","article-title":"C-reactive protein as a marker of infection in critically ill patients","volume":"11","author":"P\u00f3voa","year":"2005","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jceh.2026.103645_bib12","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/apt.18148","article-title":"Other causes of neurocognitive impairment than covert hepatic encephalopathy (CHE) are very frequent, either alone or associated with CHE , in cirrhotic patients with cognitive complaints","volume":"60","author":"Sultanik","year":"2024","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.jceh.2026.103645_bib13","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1111\/j.1532-5415.2008.01674.x","article-title":"The confusion assessment method: a systematic review of current usage","volume":"56","author":"Wei","year":"2008","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.jceh.2026.103645_bib14","doi-asserted-by":"crossref","first-page":"810","DOI":"10.5604\/01.3001.0012.3141","article-title":"A head CT is unnecessary in the initial evaluation of A cirrhotic patient with recurrent hepatic encephalopathy","volume":"17","author":"Kumar","year":"2018","journal-title":"Ann Hepatol"},{"key":"10.1016\/j.jceh.2026.103645_bib15","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgast-2021-000609","article-title":"Low yield of head CT in cirrhotic patients presenting with hepatic encephalopathy","volume":"8","author":"Hanna","year":"2021","journal-title":"BMJ Open Gastroenterol"},{"key":"10.1016\/j.jceh.2026.103645_bib16","first-page":"1","article-title":"Neurologic imaging in a patient with cirrhosis and altered mental status: to CT or not to CT","volume":"vol 2021","author":"Polyak","year":"2021"},{"key":"10.1016\/j.jceh.2026.103645_bib17","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.cgh.2014.05.022","article-title":"Low likelihood of intracranial hemorrhage in patients with cirrhosis and altered mental status","volume":"13","author":"Donovan","year":"2015","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["Journal of Clinical and Experimental Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688326001775?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0973688326001775?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T20:56:08Z","timestamp":1788900968000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0973688326001775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S0973688326001775"],"URL":"https:\/\/doi.org\/10.1016\/j.jceh.2026.103645","relation":{},"ISSN":["0973-6883"],"issn-type":[{"value":"0973-6883","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Etiological Spectrum, Outcomes, and Diagnostic Yield of Computerized Tomography of the Head in Cirrhotic Patients With Altered Mental Status","name":"articletitle","label":"Article Title"},{"value":"Journal of Clinical and Experimental Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jceh.2026.103645","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Indian National Association for Study of the Liver. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103645"}}