{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:16:02Z","timestamp":1791288962462,"version":"4.3.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":731,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","cysticfibrosisjournal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cystic Fibrosis"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.jcf.2014.04.008","type":"journal-article","created":{"date-parts":[[2014,6,3]],"date-time":"2014-06-03T00:31:37Z","timestamp":1401755497000},"page":"6-15","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Upper aero-digestive contamination by Pseudomonas aeruginosa and implications in Cystic Fibrosis"],"prefix":"10.1016","volume":"14","author":[{"given":"R.","family":"Rivas Caldas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Boisram\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcf.2014.04.008_bb0005","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s00439-002-0788-1","article-title":"Spatial and temporal distribution of cystic fibrosis and of its mutations in Brittany, France: a retrospective study from 1960","volume":"111","author":"Scotet","year":"2002","journal-title":"Hum Genet"},{"key":"10.1016\/j.jcf.2014.04.008_bb0010","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1038\/nrmicro2907","article-title":"Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective","volume":"10","author":"Folkesson","year":"2012","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0015","doi-asserted-by":"crossref","first-page":"e50731","DOI":"10.1371\/journal.pone.0050731","article-title":"Molecular epidemiology of chronic Pseudomonas aeruginosa airway infections in cystic fibrosis","volume":"7","author":"Cramer","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jcf.2014.04.008_bb0020","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.ijporl.2012.02.043","article-title":"Bacteriology of the paranasal sinuses in pediatric cystic fibrosis patients","volume":"76","author":"Digoy","year":"2012","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0025","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.jcf.2012.04.003","article-title":"Risk factors for age at initial Pseudomonas acquisition in the cystic fibrosis epic observational cohort","volume":"11","author":"Rosenfeld","year":"2012","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcf.2014.04.008_bb0030","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1164\/rccm.200408-1044SO","article-title":"Pathogen\u2013host interactions in Pseudomonas aeruginosa pneumonia","volume":"171","author":"Sadikot","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcf.2014.04.008_bb0035","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1136\/adc.65.2.175","article-title":"Bacterial reservoirs in cystic fibrosis","volume":"65","author":"Taylor","year":"1990","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jcf.2014.04.008_bb0040","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.1365-2249.2006.03151.x","article-title":"Association between mannan-binding lectin and impaired lung function in cystic fibrosis may be age-dependent","volume":"145","author":"Muhlebach","year":"2006","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0045","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/ppul.10127","article-title":"Pseudomonas aeruginosa and other predictors of mortality and morbidity in young children with cystic fibrosis","volume":"34","author":"Emerson","year":"2002","journal-title":"Pediatr Pulmonol"},{"issue":"Suppl. 6","key":"10.1016\/j.jcf.2014.04.008_bb0050","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S0300-2896(11)70029-1","article-title":"Chronic bronchial infection: the problem of Pseudomonas aeruginosa","volume":"47","author":"Canton","year":"2011","journal-title":"Arch Bronconeumol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0055","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1097\/00005537-199608000-00018","article-title":"Patterns of sinusitis in cystic fibrosis","volume":"106","author":"Gentile","year":"1996","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jcf.2014.04.008_bb0060","doi-asserted-by":"crossref","first-page":"122","DOI":"10.2500\/ajr.2007.21.2905","article-title":"The delta F508 mutation in cystic fibrosis and impact on sinus development","volume":"21","author":"Woodworth","year":"2007","journal-title":"Am J Rhinol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0065","doi-asserted-by":"crossref","first-page":"479","DOI":"10.3109\/02841859909175571","article-title":"Hypoplasia of the sphenoid sinuses as a diagnostic tool in cystic fibrosis","volume":"40","author":"Eggesbo","year":"1999","journal-title":"Acta Radiol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0070","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/028418502127347592","article-title":"CT characterization of inflammatory paranasal sinus disease in cystic fibrosis","volume":"43","author":"Eggesbo","year":"2002","journal-title":"Acta Radiol"},{"issue":"Suppl. 2","key":"10.1016\/j.jcf.2014.04.008_bb0075","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/S1569-1993(13)00150-1","article-title":"Bacterial sinusitis can be a focus for initial lung colonisation and chronic lung infection in patients with cystic fibrosis","volume":"12","author":"Aanaes","year":"2013","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcf.2014.04.008_bb0080","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s11882-012-0250-y","article-title":"Pathogenesis and management of nasal polyposis in cystic fibrosis","volume":"12","author":"Mainz","year":"2012","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.jcf.2014.04.008_bb0085","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.jcf.2013.01.002","article-title":"Importance of bacteriology in upper airways of patients with Cystic Fibrosis","volume":"12","author":"Berkhout","year":"2013","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcf.2014.04.008_bb0090","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1136\/thx.2008.104711","article-title":"Concordant genotype of upper and lower airways P. aeruginosa and S. aureus isolates in cystic fibrosis","volume":"64","author":"Mainz","year":"2009","journal-title":"Thorax"},{"key":"10.1016\/j.jcf.2014.04.008_bb0095","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1093\/infdis\/146.5.589","article-title":"Bacteriology of the maxillary sinuses in patients with cystic fibrosis","volume":"146","author":"Shapiro","year":"1982","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jcf.2014.04.008_bb0100","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/S1808-8694(15)30100-2","article-title":"Bacteriology of the middle meatus aspirate in patients with cystic fibrosis","volume":"73","author":"Franche","year":"2007","journal-title":"Braz J Otorhinolaryngol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0105","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/ppul.20396","article-title":"Are lower airway or throat cultures predictive of sinus bacteriology in cystic fibrosis?","volume":"41","author":"Muhlebach","year":"2006","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0110","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.jcf.2011.10.009","article-title":"Sinonasal persistence of Pseudomonas aeruginosa after lung transplantation","volume":"11","author":"Mainz","year":"2012","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcf.2014.04.008_bb0115","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/ismej.2011.83","article-title":"Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection","volume":"6","author":"Hansen","year":"2012","journal-title":"ISME J"},{"key":"10.1016\/j.jcf.2014.04.008_bb0120","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1128\/JCM.02411-07","article-title":"Bacterial profiles of root caries in elderly patients","volume":"46","author":"Preza","year":"2008","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0125","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1590\/S1806-37132009001100010","article-title":"Nosocomial pneumonia: importance of the oral environment","volume":"35","author":"Amaral","year":"2009","journal-title":"J Bras Pneumol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0130","doi-asserted-by":"crossref","first-page":"e42786","DOI":"10.1371\/journal.pone.0042786","article-title":"Assessing bacterial populations in the lung by replicate analysis of samples from the upper and lower respiratory tracts","volume":"7","author":"Charlson","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jcf.2014.04.008_bb0135","doi-asserted-by":"crossref","first-page":"R117","DOI":"10.1186\/cc7967","article-title":"A randomized trial of chlorhexidine gluconate on oral bacterial pathogens in mechanically ventilated patients","volume":"13","author":"Scannapieco","year":"2009","journal-title":"Crit Care"},{"key":"10.1016\/j.jcf.2014.04.008_bb0140","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0167-4943(00)00091-1","article-title":"Prevalence of potential respiratory pathogens in the mouths of elderly patients and effects of professional oral care","volume":"32","author":"Abe","year":"2001","journal-title":"Arch Gerontol Geriatr"},{"key":"10.1016\/j.jcf.2014.04.008_bb0145","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1086\/593193","article-title":"Genetic relationships between respiratory pathogens isolated from dental plaque and bronchoalveolar lavage fluid from patients in the intensive care unit undergoing mechanical ventilation","volume":"47","author":"Heo","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jcf.2014.04.008_bb0150","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.ijmm.2010.02.005","article-title":"Endotracheal tube biofilm inoculation of oral flora and subsequent colonization of opportunistic pathogens","volume":"300","author":"Perkins","year":"2010","journal-title":"Int J Med Microbiol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0155","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1399-302X.1990.tb00222.x","article-title":"Staphylococci in human periodontal diseases","volume":"5","author":"Rams","year":"1990","journal-title":"Oral Microbiol Immunol"},{"issue":"9","key":"10.1016\/j.jcf.2014.04.008_bb0160","article-title":"Periodontal pockets as potential sources of cystic fibrosis lung infection","author":"Bensel","year":"2010","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcf.2014.04.008_bb0165","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/0030-4220(85)90187-2","article-title":"Pseudomonas aeruginosa in the oral cavity and sputum of patients with cystic fibrosis","volume":"59","author":"Komiyama","year":"1985","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0170","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.archoralbio.2009.10.005","article-title":"Prevalence of potential bacterial respiratory pathogens in the oral cavity of hospitalised individuals","volume":"55","author":"Zuanazzi","year":"2010","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.jcf.2014.04.008_bb0175","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1097\/00003246-199802000-00032","article-title":"Colonization of dental plaque: a source of nosocomial infections in intensive care unit patients","volume":"26","author":"Fourrier","year":"1998","journal-title":"Crit Care Med"},{"key":"10.1016\/j.jcf.2014.04.008_bb0180","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1097\/00003246-199206000-00007","article-title":"Colonization of dental plaque by respiratory pathogens in medical intensive care patients","volume":"20","author":"Scannapieco","year":"1992","journal-title":"Crit Care Med"}],"container-title":["Journal of Cystic Fibrosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569199314000952?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569199314000952?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T13:55:47Z","timestamp":1538574947000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569199314000952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S1569199314000952"],"URL":"https:\/\/doi.org\/10.1016\/j.jcf.2014.04.008","relation":{},"ISSN":["1569-1993"],"issn-type":[{"value":"1569-1993","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Upper aero-digestive contamination by Pseudomonas aeruginosa and implications in Cystic Fibrosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Cystic Fibrosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcf.2014.04.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}