{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T23:32:39Z","timestamp":1767828759542,"version":"3.49.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"vor","delay-in-days":730,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100013443","name":"Swedish Insitute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013443","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","cysticfibrosisjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cystic Fibrosis"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.jcf.2019.10.014","type":"journal-article","created":{"date-parts":[[2019,10,28]],"date-time":"2019-10-28T20:03:43Z","timestamp":1572293023000},"page":"910-916","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Risk factors for progression of structural lung disease in school-age children with cystic fibrosis"],"prefix":"10.1016","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0194-7365","authenticated-orcid":false,"given":"Marcus","family":"Svedberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per","family":"Gustafsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harm","family":"Tiddens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Imberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldina","family":"Pivodic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Lindblad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jcf.2019.10.014_bib0001","first-page":"92","article-title":"Multi-modality monitoring of cystic fibrosis lung disease: the role of chest computed tomography","volume":"15","author":"Tiddens","year":"2014","journal-title":"Paediatr Respir Rev"},{"key":"10.1016\/j.jcf.2019.10.014_bib0002","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0033-8389(05)70009-9","article-title":"Bronchiectasis","volume":"36","author":"Hansell","year":"1998","journal-title":"Radiol Clin North Am."},{"key":"10.1016\/j.jcf.2019.10.014_bib0003","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1378\/chest.10-1152","article-title":"Bronchiectasis and pulmonary exacerbations in children and young adults with cystic fibrosis","volume":"140","author":"Loeve","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.jcf.2019.10.014_bib0004","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1183\/09031936.00137612","article-title":"Impact of bronchiectasis and trapped air on quality of life and exacerbations in cystic fibrosis","volume":"42","author":"Tepper","year":"2013","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jcf.2019.10.014_bib0005","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1164\/rccm.200901-0069OC","article-title":"Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening","volume":"180","author":"Sly","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcf.2019.10.014_bib0006","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1136\/thoraxjnl-2011-200912","article-title":"Progression of early structural lung disease in young children with cystic fibrosis assessed using CT","volume":"67","author":"Mott","year":"2012","journal-title":"Thorax"},{"key":"10.1016\/j.jcf.2019.10.014_bib0007","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1164\/rccm.201501-0061OC","article-title":"PRAGMA-CF. A quantitative structural lung disease computed tomography outcome in young children with cystic fibrosis","volume":"191","author":"Rosenow","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"issue":"Suppl 1","key":"10.1016\/j.jcf.2019.10.014_bib0008","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.1016\/j.jcf.2014.03.010","article-title":"European cystic fibrosis society standards of care: best practice guidelines","volume":"13","author":"Smyth","year":"2014","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcf.2019.10.014_bib0009","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.jcf.2016.12.008","article-title":"Chest imaging in cystic fibrosis studies: what counts, and can be counted?","volume":"16","author":"Szczesniak","year":"2017","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcf.2019.10.014_bib0010","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1183\/09031936.05.00034805","article-title":"Standardisation of spirometry","volume":"26","author":"Miller","year":"2005","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jcf.2019.10.014_bib0011","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1183\/09031936.00080312","article-title":"Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations","volume":"40","author":"Quanjer","year":"2012","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jcf.2019.10.014_bib0012","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S1569-1993(02)00141-8","article-title":"Evaluation of a new definition for chronic pseudomonas aeruginosa infection in cystic fibrosis patients","volume":"2","author":"Lee","year":"2003","journal-title":"J Cyst Fibros"},{"issue":"Suppl 1","key":"10.1016\/j.jcf.2019.10.014_bib0013","doi-asserted-by":"crossref","first-page":"i1","DOI":"10.1136\/thoraxjnl-2015-207360","article-title":"US cystic fibrosis foundation and european cystic fibrosis society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis","volume":"71","author":"Floto","year":"2016","journal-title":"Thorax"},{"key":"10.1016\/j.jcf.2019.10.014_bib0014","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1513\/AnnalsATS.201402-050AS","article-title":"Antibiotic management of lung infections in cystic fibrosis. I. the microbiome, methicillin-resistant staphylococcus aureus, gram-negative bacteria, and multiple infections","volume":"11","author":"Chmiel","year":"2014","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.jcf.2019.10.014_bib0015","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1164\/rccm.201507-1409OC","article-title":"Lung clearance index and structural lung disease on computed tomography in early cystic fibrosis","volume":"193","author":"Ramsey","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcf.2019.10.014_bib0016","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1007\/s00247-014-2964-6","article-title":"What did we learn from two decades of chest computed tomography in cystic fibrosis?","volume":"44","author":"Tiddens","year":"2014","journal-title":"Pediatr Radiol."},{"key":"10.1016\/j.jcf.2019.10.014_bib0017","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1056\/NEJMoa1301725","article-title":"Risk factors for bronchiectasis in children with cystic fibrosis","volume":"368","author":"Sly","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jcf.2019.10.014_bib0018","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1164\/rccm.201407-1277OC","article-title":"Early respiratory infection is associated with reduced spirometry in children with cystic fibrosis","volume":"190","author":"Ramsey","year":"2014","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcf.2019.10.014_bib0019","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.jcf.2017.12.002","article-title":"The association between staphylococcus aureus and subsequent bronchiectasis in children with cystic fibrosis","volume":"17","author":"Caudri","year":"2018","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcf.2019.10.014_bib0020","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1164\/rccm.201604-0893OC","article-title":"Comparison of lung clearance index and magnetic resonance imaging for assessment of lung disease in children with cystic fibrosis","volume":"195","author":"Stahl","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcf.2019.10.014_bib0021","doi-asserted-by":"crossref","DOI":"10.1136\/thoraxjnl-2017-210979","article-title":"Lung clearance index to monitor treatment response in pulmonary exacerbations in preschool children with cystic fibrosis","author":"Rayment","year":"2018","journal-title":"Thorax"},{"key":"10.1016\/j.jcf.2019.10.014_bib0022","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1183\/13993003.00622-2015","article-title":"Progressive ventilation inhomogeneity in infants with cystic fibrosis after pulmonary infection","volume":"46","author":"Simpson","year":"2015","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jcf.2019.10.014_bib0023","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1164\/rccm.201610-2158OC","article-title":"Progression of lung disease in preschool patients with cystic fibrosis","volume":"195","author":"Stanojevic","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jcf.2019.10.014_bib0024","first-page":"54","article-title":"The cumulative effect of inflammation and infection on structural lung disease in early cystic fibrosis","author":"Rosenow","year":"2019","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jcf.2019.10.014_bib0025","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/S0022-3476(05)82653-8","article-title":"Pulmonary function and clinical course in patients with cystic fibrosis after pulmonary colonization with pseudomonas aeruginosa","volume":"116","author":"Kerem","year":"1990","journal-title":"J Pediatr"},{"key":"10.1016\/j.jcf.2019.10.014_bib0026","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/(SICI)1099-0496(199705)23:5<330::AID-PPUL4>3.0.CO;2-O","article-title":"Antibiotic treatment of initial colonization with pseudomonas aeruginosa postpones chronic infection and prevents deterioration of pulmonary function in cystic fibrosis","volume":"23","author":"Frederiksen","year":"1997","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jcf.2019.10.014_bib0027","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/ppul.1144","article-title":"Early pulmonary infection, inflammation, and clinical outcomes in infants with cystic fibrosis","volume":"32","author":"Rosenfeld","year":"2001","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jcf.2019.10.014_bib0028","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.jpeds.2009.05.005","article-title":"Bronchiectasis in infants and preschool children diagnosed with cystic fibrosis after newborn screening","volume":"155","author":"Stick","year":"2009","journal-title":"J Pediatr"},{"key":"10.1016\/j.jcf.2019.10.014_bib0029","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/ppul.2009","article-title":"Acceleration of lung disease in children with cystic fibrosis after pseudomonas aeruginosa acquisition","volume":"32","author":"Kosorok","year":"2001","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jcf.2019.10.014_bib0030","first-page":"55","article-title":"A systematic review of studies examining the rate of lung function decline in patients with cystic fibrosis","volume":"20","author":"Harun","year":"2016","journal-title":"Paediatr Respir Rev"},{"key":"10.1016\/j.jcf.2019.10.014_bib0031","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.jcf.2018.04.002","article-title":"Eradication of early P. aeruginosa infection in children <7years of age with cystic fibrosis: the early study","volume":"18","author":"Ratjen","year":"2019","journal-title":"J Cyst Fibros"},{"key":"10.1016\/j.jcf.2019.10.014_bib0032","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s11046-017-0182-0","article-title":"Progress in definition, prevention and treatment of fungal infections in cystic fibrosis","volume":"183","author":"Schwarz","year":"2018","journal-title":"Mycopathologia"},{"key":"10.1016\/j.jcf.2019.10.014_bib0033","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s11046-017-0184-y","article-title":"Fungal pathogens in CF airways: leave or treat?","volume":"183","author":"Singh","year":"2018","journal-title":"Mycopathologia"},{"key":"10.1016\/j.jcf.2019.10.014_bib0034","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/ppul.23490","article-title":"Spirometer guided chest imaging in children: it is worth the effort!","volume":"52","author":"Salamon","year":"2017","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jcf.2019.10.014_bib0035","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.jcf.2013.05.012","article-title":"Improved air trapping evaluation in chest computed tomography in children with cystic fibrosis using real-time spirometric monitoring and biofeedback","volume":"12","author":"Kongstad","year":"2013","journal-title":"J Cyst Fibros"}],"container-title":["Journal of Cystic Fibrosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569199319309294?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569199319309294?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T21:43:24Z","timestamp":1761601404000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569199319309294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["S1569199319309294"],"URL":"https:\/\/doi.org\/10.1016\/j.jcf.2019.10.014","relation":{},"ISSN":["1569-1993"],"issn-type":[{"value":"1569-1993","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk factors for progression of structural lung disease in school-age children with cystic fibrosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Cystic Fibrosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcf.2019.10.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 European Cystic Fibrosis Society. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}