{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T08:13:06Z","timestamp":1788250386503,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T00:00:00Z","timestamp":1719446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","cysticfibrosisjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Cystic Fibrosis"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.jcf.2024.06.016","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T23:36:46Z","timestamp":1719963406000},"page":"977-983","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Gut microbiota in adults with cystic fibrosis: Implications for the severity of the CFTR gene mutation and nutritional status"],"prefix":"10.1016","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5895-9754","authenticated-orcid":false,"given":"Magdalena","family":"Durda-Masny","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Go\u017adzik-Spychalska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1454-9726","authenticated-orcid":false,"given":"Katarzyna","family":"Mora\u0144ska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7388-8360","authenticated-orcid":false,"given":"Natalia","family":"Paw\u0142owska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9512-2956","authenticated-orcid":false,"given":"Micha\u0142","family":"Mazurkiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9050-8927","authenticated-orcid":false,"given":"Iwona","family":"Skrzypczak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szczepan","family":"Cofta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7516-5019","authenticated-orcid":false,"given":"Anita","family":"Szwed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jcf.2024.06.016_bib0001","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1146\/annurev.physiol.62.1.467","article-title":"Role of CFTR in the colon","volume":"62","author":"Greger","year":"2000","journal-title":"Annu Rev Physiol"},{"issue":"2","key":"10.1016\/j.jcf.2024.06.016_bib0002","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s11894-017-0546-0","article-title":"The enigmatic gut in cystic fibrosis: linking inflammation, dysbiosis, and the increased risk of malignancy","volume":"19","author":"Garg","year":"2017","journal-title":"Curr Gastroenterol Rep"},{"issue":"3","key":"10.1016\/j.jcf.2024.06.016_bib0003","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1365-2982.2009.01418.x","article-title":"Enteric circular muscle dysfunction in the cystic fibrosis mouse small intestine","volume":"22","author":"De Lisle","year":"2010","journal-title":"Neurogastroenterol Motil"},{"issue":"15","key":"10.1016\/j.jcf.2024.06.016_bib0004","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.clinbiochem.2012.05.034","article-title":"Cystic fibrosis: insight into CFTR pathophysiology and pharmacotherapy","volume":"45","author":"Lubamba","year":"2012","journal-title":"Clin Biochem"},{"issue":"3","key":"10.1016\/j.jcf.2024.06.016_bib0005","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1091\/mbc.e14-04-0935","article-title":"From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations","volume":"27","author":"Veit","year":"2016","journal-title":"Mol Biol Cell"},{"issue":"1","key":"10.1016\/j.jcf.2024.06.016_bib0006","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S2213-2600(19)30337-6","article-title":"The future of cystic fibrosis care: a global perspective","volume":"8","author":"Bell","year":"2020","journal-title":"Lancet Respir Med"},{"issue":"11","key":"10.1016\/j.jcf.2024.06.016_bib0007","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.3390\/cells11111769","article-title":"CFTR modulators in people with cystic fibrosis: real-world evidence in France","volume":"11","author":"Regard","year":"2022","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.jcf.2024.06.016_bib0008","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s40101-021-00269-7","article-title":"The determinants of survival among adults with cystic fibrosis-a cohort study","volume":"40","author":"Durda-Masny","year":"2021","journal-title":"J Physiol Anthropol"},{"issue":"3","key":"10.1016\/j.jcf.2024.06.016_bib0009","first-page":"220","article-title":"A review of cystic fibrosis: basic and clinical aspects","volume":"4","author":"Chen","year":"2021","journal-title":"AMEM"},{"key":"10.1016\/j.jcf.2024.06.016_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2021.111221","article-title":"Pseudomonas aeruginosa, the type of mutation, lung function, and nutritional status in adults with cystic fibrosis","volume":"89","author":"John","year":"2021","journal-title":"Nutrition"},{"issue":"Suppl 6","key":"10.1016\/j.jcf.2024.06.016_bib0011","first-page":"341","article-title":"Biological status of adult patients with cystic fibrosis","volume":"59","author":"Kosinska","year":"2008","journal-title":"J Physiol Pharmacol"},{"issue":"9","key":"10.1016\/j.jcf.2024.06.016_bib0012","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1080\/17474124.2018.1502663","article-title":"Gastrointestinal pathophysiology and nutrition in cystic fibrosis","volume":"12","author":"Ratchford","year":"2018","journal-title":"Expert Rev Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.jcf.2024.06.016_bib0013","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3390\/microorganisms7010014","article-title":"What is the healthy gut microbiota composition? a changing ecosystem across age, environment, diet, and diseases","volume":"7","author":"Rinninella","year":"2019","journal-title":"Microorganisms"},{"issue":"11","key":"10.1016\/j.jcf.2024.06.016_bib0014","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1038\/nm.3680","article-title":"Regulatory B cells are induced by gut microbiota-driven interleukin-1\u03b2 and interleukin-6 production","volume":"20","author":"Rosser","year":"2014","journal-title":"Nat Med"},{"issue":"1","key":"10.1016\/j.jcf.2024.06.016_bib0015","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s12866-017-0968-8","article-title":"The altered gut microbiota in adults with cystic fibrosis","volume":"17","author":"Burke","year":"2017","journal-title":"BMC Microbiol"},{"key":"10.1016\/j.jcf.2024.06.016_bib0016","article-title":"2020. MetaGenomic analysis of short and long reads","author":"Manske","year":"2020","journal-title":"bioRxiv"},{"key":"10.1016\/j.jcf.2024.06.016_bib0017","doi-asserted-by":"crossref","first-page":"D633","DOI":"10.1093\/nar\/gkt1244","article-title":"Ribosomal Database Project: data and tools for high throughput rRNA analysis","volume":"42","author":"Cole","year":"2014","journal-title":"Nucl Acid Res"},{"issue":"7","key":"10.1016\/j.jcf.2024.06.016_bib0018","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1128\/JCM.00432-15","article-title":"Rapid detection of emerging pathogens and loss of microbial diversity associated with severe lung disease in cystic fibrosis","volume":"53","author":"Flight","year":"2015","journal-title":"J Clin Microbiol"},{"issue":"2","key":"10.1016\/j.jcf.2024.06.016_bib0019","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1513\/AnnalsATS.201407-310OC","article-title":"Assessment of airway microbiota and inflammation in cystic fibrosis using multiple sampling methods","volume":"12","author":"Zemanick","year":"2015","journal-title":"Ann Am Thorac Soc"},{"issue":"4","key":"10.1016\/j.jcf.2024.06.016_bib0020","doi-asserted-by":"crossref","first-page":"e61176","DOI":"10.1371\/journal.pone.0061176","article-title":"Cystic fibrosis transmembrane conductance regulator (CFTR) allelic variants relate to shifts in faecal microbiota of cystic fibrosis patients","volume":"8","author":"Schippa","year":"2013","journal-title":"PLoS ONE"},{"issue":"1","key":"10.1016\/j.jcf.2024.06.016_bib0021","doi-asserted-by":"crossref","first-page":"18593","DOI":"10.1038\/s41598-019-55028-7","article-title":"Gut microbiota in children with cystic fibrosis: a taxonomic and functional dysbiosis","volume":"9","author":"Coffey","year":"2019","journal-title":"Sci Rep"},{"issue":"3","key":"10.1016\/j.jcf.2024.06.016_bib0022","doi-asserted-by":"crossref","first-page":"e00150","DOI":"10.14309\/ctg.0000000000000150","article-title":"Disordered gut microbiota in children who have chronic pancreatitis and different functional gene mutations","volume":"11","author":"Wang","year":"2020","journal-title":"Clin Transl Gastroenterol"},{"issue":"1","key":"10.1016\/j.jcf.2024.06.016_bib0023","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3390\/microorganisms11010009","article-title":"Gut dysbiosis in children with cystic fibrosis: development, features and the role of gut-lung axis on disease progression","volume":"11","author":"Testa","year":"2022","journal-title":"Microorganisms"},{"key":"10.1016\/j.jcf.2024.06.016_bib0024","doi-asserted-by":"crossref","first-page":"24857","DOI":"10.1038\/srep24857","article-title":"Disrupted progression of the intestinal microbiota with age in children with cystic fibrosis","volume":"6","author":"Nielsen","year":"2016","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.jcf.2024.06.016_bib0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008251","article-title":"CFTR dysregulation drives active selection of the gut microbiome","volume":"16","author":"Meeker","year":"2020","journal-title":"PLoS Pathog"},{"issue":"2","key":"10.1016\/j.jcf.2024.06.016_bib0026","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/ismej.2009.112","article-title":"Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice","volume":"4","author":"Zhang","year":"2010","journal-title":"ISME J"},{"key":"10.1016\/j.jcf.2024.06.016_bib0027","doi-asserted-by":"crossref","first-page":"22493","DOI":"10.1038\/srep22493","article-title":"Metagenomic evidence for taxonomic dysbiosis and functional imbalance in the gastrointestinal tracts of children with cystic fibrosis","volume":"6","author":"Manor","year":"2016","journal-title":"Sci Rep"},{"issue":"3","key":"10.1016\/j.jcf.2024.06.016_bib0028","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.3390\/ijms24032720","article-title":"Gut microbiota changes during dimethyl fumarate treatment in patients with multiple sclerosis","volume":"24","author":"Ferri","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"4","key":"10.1016\/j.jcf.2024.06.016_bib0029","doi-asserted-by":"crossref","DOI":"10.1128\/msphere.00046-23","article-title":"Development of the intestinal microbiome in cystic fibrosis in early life","volume":"8","author":"Price","year":"2023","journal-title":"mSphere"},{"issue":"1","key":"10.1016\/j.jcf.2024.06.016_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2021.1875796","article-title":"Blautia-a new functional genus with potential probiotic properties?","volume":"13","author":"Liu","year":"2021","journal-title":"Gut Microbes"}],"container-title":["Journal of Cystic Fibrosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569199324007859?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1569199324007859?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T07:14:35Z","timestamp":1788246875000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1569199324007859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S1569199324007859"],"URL":"https:\/\/doi.org\/10.1016\/j.jcf.2024.06.016","relation":{},"ISSN":["1569-1993"],"issn-type":[{"value":"1569-1993","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gut microbiota in adults with cystic fibrosis: Implications for the severity of the CFTR gene mutation and nutritional status","name":"articletitle","label":"Article Title"},{"value":"Journal of Cystic Fibrosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jcf.2024.06.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society.","name":"copyright","label":"Copyright"}]}}