{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:23:46Z","timestamp":1761513826383},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Chemical Neuroanatomy"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.jchemneu.2016.05.009","type":"journal-article","created":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T10:27:57Z","timestamp":1464863277000},"page":"93-99","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Comparing glutamatergic neuron population in the mediodorsal thalamic nucleus of genetic absence epilepsy rats from strasbourg (GAERS) and normal control Wistar rats"],"prefix":"10.1016","volume":"77","author":[{"given":"Safiye","family":"\u00c7avdar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merve","family":"\u00d6zg\u00fcr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zlem","family":"Kirazl\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ser\u00e7in","family":"Karah\u00fcseyino\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filiz","family":"Onat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jchemneu.2016.05.009_bib0005","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s12264-013-1402-3","article-title":"Comparison of numbers of interneurons in three thalamic nuclei of normal and epileptic rats","volume":"30","author":"\u00c7avdar","year":"2013","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0010","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1142\/S0219635214500198","article-title":"Motor afferents from the cerebellum, zona incerta and substantia nigra to the mediodorsal thalamic nucleus in the rat","volume":"13","author":"\u00c7avdar","year":"2014","journal-title":"J. Integr. Neurosci."},{"issue":"6\u20137","key":"10.1016\/j.jchemneu.2016.05.009_bib0015","first-page":"333","article-title":"The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention","volume":"51","author":"Amanda","year":"2007","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0020","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s00424-010-0809-1","article-title":"Glutamate receptors, neurotoxicity and neurodegeneration","volume":"460","author":"Anthony","year":"2010","journal-title":"Eur. J. Physiol."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0025","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0920-1211(96)00037-X","article-title":"Cortical versus thalamic mechanisms underlying spike and wave discharges in GAERS","volume":"26","author":"Avanzini","year":"1996","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0030","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/0014-4886(82)90112-1","article-title":"Interaction of cortex and thalamus in spike and wave discharges of feline generalized penicillin epilepsy","volume":"76","author":"Avoli","year":"1982","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0035","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1142\/S021963521350012X","article-title":"Regional connections of the mediodorsal thalamic nucleus in the rat","volume":"12","author":"Bay","year":"2013","journal-title":"J. Integr. Neurosci."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0040","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0920-1211(94)90050-7","article-title":"Thalamic mediodorsal and intralaminar nuclear lesions disrupt the generation of experimentally induced generalized absence-like seizures in rats","volume":"17","author":"Benerjee","year":"1994","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0045","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0028-3908(94)00134-E","article-title":"Thalamic NMDA receptors in the \u03b3-hydroxybutrate model of absence seizure: a cerebral micro injection study in rats","volume":"34","author":"Benerjee","year":"1995","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0050","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1528-1157.2000.tb01548.x","article-title":"The pathological substrate of limbic epilepsy: neuronal loss in the medial dorsal thalamic nucleus as the consistent change","volume":"6","author":"Bertram","year":"2000","journal-title":"Epilepsia Suppl."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0055","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.neuroimage.2008.12.019","article-title":"Morphometric abnormalities and hyperanxiety in genetically epileptic rats: a model of psychiatric comorbidity?","volume":"45","author":"Bouilleret","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0060","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/0166-2236(91)90178-W","article-title":"A role for GABAB receptors in excitation and inhibition of thalamocortical cells","volume":"14","author":"Crunelli","year":"1991","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0065","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0920-9964(02)00297-9","article-title":"A postmortem study of the mediodorsal nucleus of the thalamus in schizophrenia","volume":"60","author":"Cullen","year":"2003","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0070","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0301-0082(97)00091-9","article-title":"Pathophysiological mechanisms of genetic absence epilepsy in the rat","volume":"55","author":"Danober","year":"1998","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0075","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1002\/jnr.10086","article-title":"Metabolic approach of absence seizures in a genetic model of absence epilepsy, the GAERS: study of the leucine-glutamate cycle","volume":"66","author":"Dufour","year":"2001","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0080","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/1098-1136(200010)32:1<15::AID-GLIA20>3.0.CO;2-#","article-title":"Specific alteration in the expression of glial fibrillary acidic protein, glutamate dehydrogenase, and glutamine synthetase in rats with genetic absence epilepsy","volume":"32","author":"Dutuit","year":"2000","journal-title":"Glia"},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0085","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1046\/j.0022-3042.2002.00768.x","article-title":"Decreased expression of glutamate transporters in genetic absence epilepsy rats before seizure occurrence","volume":"80","author":"Dutuit","year":"2002","journal-title":"J. Neurochem."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0090","first-page":"245","article-title":"Neuropathological correlates of memory dysfunction in the Wernicke-Korsakoff syndrome","volume":"2","author":"Halliday","year":"1994","journal-title":"Alcohol Alcohol. Suppl."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0095","doi-asserted-by":"crossref","first-page":"3593","DOI":"10.1523\/JNEUROSCI.21-10-03593.2001","article-title":"Status epilepticus causes necrotic damage in the mediodorsal nucleus of the thalamus in immature rats","volume":"21","author":"Kubov\u00e1","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0100","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1136\/jnnp.2006.113654","article-title":"Thalamic chronotaraxis: isolated time disorientation","volume":"78","author":"Kumral","year":"2007","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0105","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/cne.903260106","article-title":"Neuronal and synaptic composition of the mediodorsal thalamic nucleus in the rat: a light and electron microscopic Golgi study","volume":"326","author":"Kuroda","year":"1992","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0110","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.3174\/ajnr.A2195","article-title":"White matter microstructure changes in the thalamus in Parkinson disease with depression: a diffusion tensor MR imaging study","volume":"31","author":"Li","year":"2010","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0115","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1159\/000111349","article-title":"Neurotransmitters regulate energy metabolism in astrocytes: implications for the metabolic trafficking between neural cells","volume":"15","author":"Magistretti","year":"1993","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0120","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/BF02229083","article-title":"Genetic absence epilepsy in rats from strasbourg (GAERS)","volume":"16","author":"Marescaux","year":"1995","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0125","first-page":"179","article-title":"GABAB receptor antagonists potential new anti-absence drugs","volume":"35","author":"Marescaux","year":"1992","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0130","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.neuint.2004.03.007","article-title":"Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer\u2019s disease","volume":"45","author":"Matthew","year":"2004","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0135","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0301-0082(92)90012-4","article-title":"Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity","volume":"39","author":"McCormick","year":"1992","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0140","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0006-8993(84)90481-5","article-title":"Differential participation of some \u2018specific\u2019 and \u2018non-specific\u2019 thalamic nuclei in generalized spike and wave discharges of feline generalized penicillin epilepsy","volume":"307","author":"McLachlan","year":"1984","journal-title":"Brain Res."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0145","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/ana.410290113","article-title":"Local cerebral glucose utilization in rats with petit mal-like seizures","volume":"29","author":"Nehlig","year":"1991","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0150","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1600-0447.2009.01447.x","article-title":"Schizophrenia; from structure to function with special focus on the mediodorsal thalamic prefrontal loop","volume":"120","author":"Pakkenberg","year":"2009","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0155","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/0361-9230(94)90237-2","article-title":"Interactions between NMDA and nonNMDA receptors in nonconvulsive epilepsy in the WAG\/Rij inbred strain","volume":"33","author":"Peeters","year":"1994","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0160","first-page":"291","article-title":"Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle","volume":"20","author":"Pellerin","year":"1998","journal-title":"Dev. Neurobiol."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0165","doi-asserted-by":"crossref","first-page":"6590","DOI":"10.1523\/JNEUROSCI.0753-07.2007","article-title":"Deep layer somatosensory cortical neurons initiate spike-and-wave discharges in a genetic model of absence epilepsy","volume":"27","author":"Polack","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0170","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0920-1211(96)00038-1","article-title":"No loss in total neuron number in the thalamic reticular nucleus and neocortex in the genetic absence epilepsy rats from Strasbourg","volume":"26","author":"Sabers","year":"1996","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0175","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s004010051038","article-title":"Nerve cell loss in the thalamic mediodorsal nucleus in Huntington\u2019s disease. II. Optimization of a stereological estimation procedure","volume":"97","author":"Schmitz","year":"1999","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0180","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1111\/epi.12403","article-title":"Regional thalamic neuropathology in patients with hippocampal sclerosis and epilepsy: a postmortem study","volume":"54","author":"Sinjab","year":"2013","journal-title":"Epilepsia"},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0185","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1111\/j.1528-1167.2008.01790.x","article-title":"Changes in midline thalamic recruiting responses in the prefrontal cortex of the rat during the development of chronic limbic seizures","volume":"50","author":"Sloan","year":"2009","journal-title":"Epilepsia"},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0190","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0006-8993(94)90874-5","article-title":"The ontogeny of [3H] gamma-hydroxybutyrate and [3H]GABAB binding sites: relation to the development of experimental absence seizures","volume":"659","author":"Snead","year":"1994","journal-title":"Brain Res."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0195","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/ana.410370204","article-title":"Basic mechanisms of generalized absence seizures","volume":"37","author":"Snead","year":"1995","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0200","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/0306-4522(83)90168-9","article-title":"Cortical relay neurons and interneurons in the N. ventralis posterolateralis of cats: a horseradish peroxidase electronmicroscopic, Golgi and immunocytochemical study","volume":"9","author":"Spreafico","year":"1983","journal-title":"Neuroscience"},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0205","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/1471-2202-8-69","article-title":"Glutamatergic alterations in the cortex of genetic absence epilepsy rats","volume":"8","author":"Touret","year":"2007","journal-title":"BMC Neurosci."},{"issue":"Suppl","key":"10.1016\/j.jchemneu.2016.05.009_bib0210","first-page":"71","article-title":"Cortical and thalamic lessions in the rats with genetic absence epilepsy","volume":"35","author":"Vergnes","year":"1992","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0215","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0304-3940(82)90136-7","article-title":"Spontaneous paroxysmal electroclinical patterns in rat: a model of generalized non-convulsive epilepsy","volume":"33","author":"Vergnes","year":"1982","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0220","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0006-8993(86)80011-7","article-title":"Ontogeny of spontaneous petit mal-like seizures in Wistar rats","volume":"395","author":"Vergnes","year":"1986","journal-title":"Brain Res."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0225","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0014-4886(87)90174-9","article-title":"Spontaneous spike and wave discharges in thalamus and cortex in a rat model of genetic petit mal-like seizures","volume":"96","author":"Vergnes","year":"1987","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.jchemneu.2016.05.009_bib0230","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1176\/appi.ajp.161.7.1270","article-title":"Elevated neuron number in the limbic thalamus in major depression","volume":"161","author":"Young","year":"2004","journal-title":"Am. J. Psychiatry"}],"container-title":["Journal of Chemical Neuroanatomy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0891061815300466?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0891061815300466?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,27]],"date-time":"2019-04-27T16:32:09Z","timestamp":1556382729000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0891061815300466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":46,"alternative-id":["S0891061815300466"],"URL":"https:\/\/doi.org\/10.1016\/j.jchemneu.2016.05.009","relation":{},"ISSN":["0891-0618"],"issn-type":[{"value":"0891-0618","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparing glutamatergic neuron population in the mediodorsal thalamic nucleus of genetic absence epilepsy rats from strasbourg (GAERS) and normal control Wistar rats","name":"articletitle","label":"Article Title"},{"value":"Journal of Chemical Neuroanatomy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jchemneu.2016.05.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}